Firing probability and mean firing rates of human muscle vasoconstrictor neurones are elevated during chronic asphyxia

Journal of Physiology

Volumn 588, Issue 4, 2010, Pages 701-712

  Ashley, Cynthia ^a,b   Burton, Danielle ^a,c   Sverrisdottir, Yrsa B ^d   Sander, Mikael ^e   McKenzie, David K ^a,b   Macefield, Vaughan G ^a,c  

^a NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^b PRINCE OF WALES HOSPITAL   (Australia)

^c UNIVERSITY OF WESTERN SYDNEY   (Australia)

^d SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^e University of Copenhagen   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; ASPHYXIA; BLOOD GAS ANALYSIS; BODY MASS; BRONCHIECTASIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HYPOXEMIA; MALE; MUSCLE ACTION POTENTIAL; PRIORITY JOURNAL; SLEEP APNEA SYNDROME; SYMPATHETIC NERVE; SYSTOLIC BLOOD PRESSURE; VASOCONSTRICTION; ADRENERGIC STIMULATION; FIRING PROBABILITY; FIRING RATE; FORCED VITAL CAPACITY; HUMAN TISSUE; MUSCLE SYMPATHETIC NERVE ACTIVITY; NERVE CELL MEMBRANE POTENTIAL; PERONEUS NERVE; SLEEP DISORDERED BREATHING; SPIKE;

EID: 77949515897     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2009.185348     Document Type: Article

References (53)

1. Carlsson JT, Hedner J, Elam M, Ejnell H, Sellgren J, Wallin BG. Augmented resting sympathetic activity in awake patients with obstructive sleep apnea. Chest 1993, 103:1763-1768.
2. Carlsson JT, Hedner J, Sellgren J, Elam M, Wallin BG. Depressed baroreflex sensitivity in patients with obstructive sleep apnea. Am J Respir Crit Care Med 1996, 154:1490-1496.
3. Cremona G, Higenbottam TW, Bower EA, Wood AM, Stewart S. Hemodynamic effects of basal and stimulated release of endogenous nitric oxide in isolated human lungs. Circulation 1999, 100:1316-1321.
4. De Troyer A, Leeper JB, McKenzie DK, Gandevia SC. Neural drive to the diaphragm in patients with severe COPD. Am J Respir Crit Care Med 1997, 155:1335-1340.
5. Elam M, Macefield VG. Multiple firing of single muscle vasoconstrictor neurons during cardiac dysrhythmias in human heart failure. J Appl Physiol 2001, 91:717-724.
6. Elam M, Macefield VG, McKenzie D. The firing pattern of single muscle vasoconstrictor neurons in awake patients with the obstructive sleep apnoea syndrome. J Appl Physiol 2002, 93:297-303.
7. Falk JA, Kadiev S, Criner GJ, Scharf SM, Minai OA, Diaz P. Cardiac disease in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008, 5:543-548.
8. Fischer T, Schobel HP, Frank H, Andreae M, Schneider KY, Heusser K. Pregnancy-induced sympathetic hyperactivity: a precursor of preeclampsia. Eur J Clin Invest 2004, 34:443-448.
9. Flenley DC. Chronic obstructive pulmonary disease. Dis Mon 1988, 34:537-599.
10. Foresi A, Leone C, Olivieri D, Cremona G. Alveolar-derived exhaled nitric oxide is reduced in obstructive sleep apnea syndrome. Chest 2007, 132:860-867.
11. Gandevia SC, Leeper JB, McKenzie DK, De Troyer A. Discharge frequencies of parasternal intercostal and scalene motor units during breathing in normal and COPD subjects. Am J Respir Crit Care Med 1996, 153:622-628.
12. Gorman RB, McKenzie DK, Butler JE, Tolman JF, Gandevia SC. Diaphragm length and neural drive after lung-volume reduction surgery. Am J Respir Crit Care Med 2005, 172:1259-1266.
13. Grassi G, Colombo M, Seravalle G, Spaziani D, Mancia G. Dissociation between muscle and skin sympathetic nerve activity in essential hypertension, obesity, and congestive heart failure. Hypertension 1998, 31:64-67.
14. Grassi G, Seravalle G, Cattaneo BM, Lanfranchi A, Vailati S, Giannattasio C, Del Bo A, Sala C, Bolla GB, Pozzi M. Sympathetic activation and loss of reflex sympathetic control in mild congestive heart failure. Circulation 1995, 92:3206-3211.
15. Hansen J, Sander M. Sympathetic neural overactivity in healthy humans after prolonged exposure to hypobaric hypoxia. J Physiol 2003, 546:921-929.
16. Hart EC, Joyner MJ, Wallin BG, Johnson CP, Curry TB, Eisenach JH, Charkoudian N. Age-related changes in the sympathetic-hemodynamic balance in men. Hypertension 2009, 54:127-133.
17. Hausberg M, Kosch M, Harmelink P, Barenbrock M, Hohage H, Kisters K, Dietl KH, Rahn KH. Sympathetic nerve activity in end-stage renal disease. Circulation 2002, 106:1974-1979.
18. Hedner J, Ejnell H, Sellgren J, Hedner T, Wallin G. Is high and fluctuating muscle nerve sympathetic activity in the sleep apnoea syndrome of pathogenetic importance for the development of hypertension?. J Hypertens Suppl 1988, 6:S529-S531.
19. Heindl S, Lehnert M, Criée CP, Hasenfuss G, Andreas S. Marked sympathetic activation in patients with chronic respiratory failure. Am J Respir Crit Care Med 2001, 164:597-601.
20. Hiestand D, Phillips B. The overlap syndrome: chronic obstructive pulmonary disease and obstructive sleep apnea. Crit Care Clin 2008, 24:551-563.
21. Howard P. Natural history of obstructive airways disease and hypoxia: implications for therapy. Lung 1990, 168(Suppl.):743-750.
22. Ilowite J, Spiegler P, Chawla S. Bronchiectasis: new findings in the pathogenesis and treatment of this disease. Curr Opin Infect Dis 2008, 21:163-167.
23. Johansson M, Elam M, Rundqvist B, Eisenhofer G, Herlitz H, Lambert G, Friberg P. Increased sympathetic nerve activity in renovascular hypertension. Circulation 1999, 18:2537-2542.
24. Lahana A, Constantopulos S, Nakos G. The local component of the acute cardiovascular response to simulated apneas in brain-dead humans. Chest 2005, 128:634-639.
25. Lambert E, Straznicky N, Schlaich M, Esler M, Dawood T, Hotchkin E, Lambert G. Differing pattern of sympathoexcitation in normal-weight and obesity-related hypertension. Hypertension 2007, 50:862-868.
26. Lazarus A, Myers J, Fuhrer G. Bronchiectasis in adults: a review. Postgrad Med 2008, 120:113-121.
27. Leimbach WN, Wallin BG, Victor RG, Aylward PE. Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation 1986, 73:913-919.
28. Macefield VG. Single-minded about heart failure. J Physiol 2009, 587:2421.
29. Macefield VG, Elam M, Wallin BG. Firing properties of single postganglionic sympathetic neurones recorded in awake human subjects. Autonom Neurosci 2002, 95:146-159.
30. Macefield VG, Rundqvist B, Sverrisdottir YB, Wallin BG, Elam M. Firing properties of single muscle vasoconstrictor neurons in the sympathoexcitation associated with congestive heart failure. Circulation 1999, 100:1708-1713.
31. Macefield VG, Sverrisdottir YB, Elam E, Harris J. Firing properties of sudomotor neurones in hyperhidrosis and thermal sweating. Clin Autonom Res 2008, 18:325-330.
32. Macefield VG, Wallin BG. Firing properties of single vasoconstrictor motoneurones in subjects with high levels of muscle sympathetic activity. J Physiol 1999, 516:293-301.
33. Macefield VG, Wallin BG, Vallbo A. The discharge behaviour of single vasoconstrictor motoneurones in human muscle nerves. J Physiol 1994, 481:799-809.
34. McKenzie DK, Frith PA, Burdon JGW, Town GI. The COPDX Plan: Australian and New Zealand Guidelines for the management of Chronic Obstructive Pulmonary Disease 2003. Med J Aust 2003, 178(Suppl.):S1-S40.
35. Mannino DM, Thorn D, Swensen A, Holguin F. Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J 2008, 32:962-969.
36. Miyajima E, Yamada Y, Yoshida Y, Matsukawa T, Shionoiri H, Tochikubo O, Ishii M. Muscle sympathetic nerve activity in renovascular hypertension and primary aldosteronism. Hypertension 2001, 17:1057-1062.
37. Morgan BJ, Crabtree DC, Palta M, Skatrud JB. Combined hypoxia and hypercapnia evokes long-lasting sympathetic activation in humans. J Appl Physiol 1995, 79:205-213.
38. Murai H, Takamura M, Maruyama M, Nakano M, Ikeda T, Kobayashi D, Otowa K, Ootsuji H, Okajima M, Furusho H, Takata S, Kaneko S. Altered firing pattern of single-unit muscle sympathetic nerve activity during handgrip exercise in chronic heart failure. J Physiol 2009, 587:2613-2622.
39. Narkiewicz K, Pesek CA, Kato M, Phillips BG, Davison DE, Somers VK. Baroreflex control of sympathetic nerve activity and heart rate in obstructive sleep apnea. Hypertension 1998, 32:1039-1043.
40. Narkiewicz K, van de Borne PJH, Pesek CA, Dyken ME, Montano N, Somers VK. Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea. Circulation 1999, 99:1183-1189.
41. Raupach T, Bahr F, Herrmann P, Luethje L, Heusser K, Hasenfuss G, Bernardi L, Andreas S. Slow breathing reduces sympathoexcitation in COPD. Eur Respir J 2008, 32:387-392.
42. Ryu JH, Scanlon PD. Obstructive lung diseases: COPD, asthma, and many imitators. Mayo Clin Proc 2001, 76:1144-1153.
43. Schlaich MP, Lambert E, Kaye DM, Krozowski Z, Campbell DJ, Lambert G, Hastings J, Aggarwal A, Esler MD. Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation. Hypertension 2004, 43:169-175.
44. Schlaich MP, Socratous F, Hennebry S, Eikelis N, Lambert EA, Straznicky N, Esler MD, Lambert GW. Sympathetic activation in chronic renal failure. J Am Soc Nephrol 2009, 20:933-939.
45. Schobel HP, Fischer T, Heuszer K, Geier H, Schmeider RE. Preeclampsia - a state of sympathetic hyperactivity. N Engl J Med 1996, 335:1480-1485.
46. Sin DD, Anthoniesen NR, Soriano JB, Agusti AG. Mortality in COPD: Role of comorbidities. Eur Respir J 2006, 28:1245-1257.
47. Sin DD, Man SFP. Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary disease. Circulation 2003, 107:1514-1519.
48. Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995, 96:1897-1904.
49. Somers VK, Mark AL, Zavala DC, Abboud FM. Contrasting effects of hypoxia and hypercapnia on ventilation and sympathetic activity in humans. J Appl Physiol 1989, 67:2101-2106.
50. Sverrisdóttir YB, Johannsson G, Jungersten L, Wallin BG, Elam MJ. Is the somatotropic axis related to sympathetic nerve activity in healthy ageing men?. Hypertension 2001, 19:2019-2024.
51. Tamisier R, Anand A, Nieto LM, Cunnington D, Weiss JW. Arterial pressure and muscle sympathetic nerve activity are increased after two hours of sustained but not cyclic hypoxia in healthy humans. J Appl Physiol 2005, 98:343-349.
52. Tuncel M, Augustyniak R, Zhang W, Toto RD, Victor RG. Sympathetic nervous system function in renal hypertension. Curr Hypertens Rep 2002, 4:229-236.
53. Zamarrón C, García Paz V, Morete E, del Campo Matías F. Association of chronic obstructive pulmonary disease and obstructive sleep apnea consequences. Int J Chron Obstruct Pulmon Dis 2008, 3:671-682.