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Volumn 10, Issue I, 2008, Pages

Advances in antiplatelet therapy: Overview of new P2Y12 receptor antagonists in development

Author keywords

Acute coronary syndrome; Antithrombotic drugs; AZD6140; Cangrelor; Clopidogrel; Prasugrel

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; AR C 69931 MX; CANGRELOR; CLOPIDOGREL; DRUG METABOLITE; HEPARIN; PLACEBO; PRASUGREL; PURINERGIC P2Y12 RECEPTOR; R 138727; R 95913; TICAGRELOR; TICLOPIDINE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

EID: 77949499925     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1093/eurheartj/sun037     Document Type: Conference Paper
Times cited : (10)

References (21)
  • 1
    • 0032858002 scopus 로고    scopus 로고
    • ADP receptors and clinical bleeding disorders
    • Cattaneo M, Gachet C. ADP receptors and clinical bleeding disorders. Arterioscler Thromb Vasc Biol 1999;19:2281-2285.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2281-2285
    • Cattaneo, M.1    Gachet, C.2
  • 2
    • 0141609789 scopus 로고    scopus 로고
    • Inherited platelet-based bleeding disorders
    • Cattaneo M. Inherited platelet-based bleeding disorders. J Thromb Haemost 2003;1:1628-1636.
    • (2003) J Thromb Haemost , vol.1 , pp. 1628-1636
    • Cattaneo, M.1
  • 3
    • 84884782925 scopus 로고    scopus 로고
    • ADP receptors antagonists
    • Michelson AD ed., San Diego, CA: Academic Press
    • Cattaneo M. ADP receptors antagonists. In: Michelson AD, ed. Platelets. San Diego, CA: Academic Press; 2006. p.1127-1144.
    • (2006) Platelets , pp. 1127-1144
    • Cattaneo, M.1
  • 5
    • 9144270451 scopus 로고    scopus 로고
    • European Society of Cardiology. Expert consensus document on the use of antiplatelet agents: The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European Society of Cardiology
    • Patrono C, Bachmann F, Baigent C, Bode C, De Caterina R, Charbonnier B, Fitzgerald D, Hirsh J, Husted S, Kvasnicka J, European Society of Cardiology. Expert consensus document on the use of antiplatelet agents: the task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European Society of Cardiology. Eur Heart J 2004;25:166-181.
    • (2004) Eur Heart J , vol.25 , pp. 166-181
    • Patrono, C.1    Bachmann, F.2    Baigent, C.3    Bode, C.4    De Caterina, R.5    Charbonnier, B.6    Fitzgerald, D.7    Hirsh, J.8    Husted, S.9    Kvasnicka, J.10
  • 6
    • 0035671531 scopus 로고    scopus 로고
    • Effect of clopidogrel on bleeding after coronary artery bypass surgery
    • Yende S, Wunderink RG. Effect of clopidogrel on bleeding after coronary artery bypass surgery. Crit Care Med 2001;29:2271-2275.
    • (2001) Crit Care Med , vol.29 , pp. 2271-2275
    • Yende, S.1    Wunderink, R.G.2
  • 7
    • 0037125390 scopus 로고    scopus 로고
    • The effect of clopidogrel in combination with aspirin when given before coronary artery bypass grafting
    • Hongo RH, Ley J, Dick SE, Yee RR. The effect of clopidogrel in combination with aspirin when given before coronary artery bypass grafting. J Am Coll Cardiol 2002;40:231-237.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 231-237
    • Hongo, R.H.1    Ley, J.2    Dick, S.E.3    Yee, R.R.4
  • 9
    • 8344231455 scopus 로고    scopus 로고
    • Aspirin and clopidogrel. Efficacy safety and the issue of drug resistance
    • Cattaneo M. Aspirin and clopidogrel. Efficacy, safety and the issue of drug resistance. Arterioscler Thromb Vasc Biol 2004;24:1980-1987.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1980-1987
    • Cattaneo, M.1
  • 11
    • 33845451677 scopus 로고    scopus 로고
    • A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation
    • Brandt JT, Payne CD, Wiviott SD, Weerakkody G, Farid NA, Small DS, Jakubowski JA, Naganuma H, Winters KJ. A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation. Am Heart J 2007;153:66.e9-66.e16.
    • (2007) Am Heart J , vol.153 , Issue.66
    • Brandt, J.T.1    Payne, C.D.2    Wiviott, S.D.3    Weerakkody, G.4    Farid, N.A.5    Small, D.S.6    Jakubowski, J.A.7    Naganuma, H.8    Winters, K.J.9
  • 13
    • 34250714831 scopus 로고    scopus 로고
    • The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite
    • Sugidachi A, Ogawa T, Kurihara A, Hagihara K, Jakubowski JA, Hashimoto M, Niitsu Y, Asai F. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost 2007; 5:1545-1551.
    • (2007) J Thromb Haemost , vol.5 , pp. 1545-1551
    • Sugidachi, A.1    Ogawa, T.2    Kurihara, A.3    Hagihara, K.4    Jakubowski, J.A.5    Hashimoto, M.6    Niitsu, Y.7    Asai, F.8
  • 16
    • 37349111065 scopus 로고    scopus 로고
    • Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: The Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial
    • PRINCIPLE-TIMI 44 Investigators
    • Wiviott SD, Trenk D, Frelinger AL, O'Donoghue M, Neumann FJ, Michelson AD, Angiolillo DJ, Hod H, Montalescot G, Miller DL, Jakubowski JA, Cairns R, Murphy SA, McCabe CH, Antman EM, Braunwald E, PRINCIPLE-TIMI 44 Investigators. Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation 2007;116:2923-2932.
    • (2007) Circulation , vol.116 , pp. 2923-2932
    • Wiviott, S.D.1    Trenk, D.2    Frelinger, A.L.3    O'Donoghue, M.4    Neumann, F.J.5    Michelson, A.D.6    Angiolillo, D.J.7    Hod, H.8    Montalescot, G.9    Miller, D.L.10    Jakubowski, J.A.11    Cairns, R.12    Murphy, S.A.13    McCabe, C.H.14    Antman, E.M.15    Braunwald, E.16
  • 19
    • 34548849756 scopus 로고    scopus 로고
    • 12 platelet receptor inhibition as an adjunct to reduced-dose alteplase during acute myocardial infarction: Results of the Safety Tolerability and Effect on Patency in Acute Myocardial Infarction STEP-AMI) angiographic trial
    • 12 platelet receptor inhibition as an adjunct to reduced-dose alteplase during acute myocardial infarction: results of the Safety, Tolerability and Effect on Patency in Acute Myocardial Infarction STEP-AMI) angiographic trial. Am Heart J 2007; 154:702-709.
    • (2007) Am Heart J , vol.154 , pp. 702-709
    • Greenbaum, A.B.1    Ohman, E.M.2    Gibson, C.M.3    Borzak, S.4    Stebbins, A.L.5    Lu, M.6    Le May, M.R.7    Stankowski, J.E.8    Emanuelsson, H.9    Weaver, W.D.10
  • 21
    • 35548995394 scopus 로고    scopus 로고
    • Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: Primary results of the DISPERSE-2 trial
    • DISPERSE-2 Investigators
    • Cannon CP, Husted S, Harrington RA, Scirica BM, Emanuelsson H, Peters G, Storey RF, DISPERSE-2 Investigators. Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE-2 trial. J Am Coll Cardiol 2007;50: 1844-1851.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1844-1851
    • Cannon, C.P.1    Husted, S.2    Harrington, R.A.3    Scirica, B.M.4    Emanuelsson, H.5    Peters, G.6    Storey, R.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.