-
1
-
-
0035206443
-
Minireview: The OPG/RANKL/RANK system
-
doi:10.1210/en.142.12.5050
-
Khosla S. Minireview: the OPG/RANKL/RANK system. Endocrinology 2001; 142:5050-5. doi:10.1210/en.142.12.5050
-
(2001)
Endocrinology
, vol.142
, pp. 5050-5055
-
-
Khosla, S.1
-
2
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
doi:10.1016/S0092-8674(00)81569-X
-
Lacey DL, Timms E, Tan HL et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998; 93:165-76. doi:10.1016/S0092-8674(00)81569-X
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
-
3
-
-
13044316551
-
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
-
doi:10.1073/pnas.96.7.3540
-
Hsu H, Lacey DL, Dunstan CR et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci USA 1999; 96:3540-5. doi:10.1073/pnas.96.7.3540
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3540-3545
-
-
Hsu, H.1
Lacey, D.L.2
Dunstan, C.R.3
-
4
-
-
0036218666
-
RANK-L and RANK: T cells, bone loss, and mammalian evolution
-
doi:10.1146/annurev.immunol.20.100301.064753
-
Theill LE, Boyle WJ, Penninger JM. RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol 2002; 20:795-823. doi:10.1146/annurev.immunol.20.100301.064753
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 795-823
-
-
Theill, L.E.1
Boyle, W.J.2
Penninger, J.M.3
-
6
-
-
0034522030
-
The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated
-
doi:10.1210/en.141.12.4768
-
Gori F, Hofbauer LC, Dunstan CR et al. The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated. Endocrinology 2000; 141:4768-76. doi:10.1210/en.141.12.4768
-
(2000)
Endocrinology
, vol.141
, pp. 4768-4776
-
-
Gori, F.1
Hofbauer, L.C.2
Dunstan, C.R.3
-
7
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
doi:10.1038/16852
-
Kong YY, Yoshida H, Sarosi I et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397:315-23. doi:10.1038/16852
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
-
8
-
-
0033568341
-
RANK is essential for osteoclast and lymph node development
-
doi:10.1101/gad.13.18.2412
-
Dougall WC, Glaccum M, Charrier K et al. RANK is essential for osteoclast and lymph node development. Genes Dev 1999; 13:2412-24. doi:10.1101/gad.13.18.2412
-
(1999)
Genes Dev
, vol.13
, pp. 2412-2424
-
-
Dougall, W.C.1
Glaccum, M.2
Charrier, K.3
-
9
-
-
56549098575
-
RANK/RANKL: Regulators of immune responses and bone physiology
-
doi:10.1196/annals.1443.016
-
Leibbrandt A, Penninger JM. RANK/RANKL: regulators of immune responses and bone physiology. Ann N Y Acad Sci 2008; 1143:123-50. doi:10.1196/annals.1443.016
-
(2008)
Ann N Y Acad Sci
, vol.1143
, pp. 123-150
-
-
Leibbrandt, A.1
Penninger, J.M.2
-
10
-
-
58149308297
-
Infantile malignant, autosomal recessive osteopetrosis: The rich and the poor
-
doi:10.1007/s00223-008-9196-4
-
Villa A, Guerrini M, Cassani B et al. Infantile malignant, autosomal recessive osteopetrosis: the rich and the poor. Calcif Tissue Int 2009; 84:1-12. doi:10.1007/s00223-008-9196-4
-
(2009)
Calcif Tissue Int
, vol.84
, pp. 1-12
-
-
Villa, A.1
Guerrini, M.2
Cassani, B.3
-
11
-
-
0037795675
-
Bone and celiac disease
-
doi:10.1007/s00223-001-2131-6
-
Bianchi ML, Bardella MT. Bone and celiac disease. Calcif Tissue Int 2002; 71:465-71. doi:10.1007/s00223-001-2131-6
-
(2002)
Calcif Tissue Int
, vol.71
, pp. 465-471
-
-
Bianchi, M.L.1
Bardella, M.T.2
-
12
-
-
39849084638
-
Low body mass not vitamin D receptor polymorphisms predict osteoporosis in patients with inflammatory bowel disease
-
Noble CL, McCullough J, Ho W et al. Low body mass not vitamin D receptor polymorphisms predict osteoporosis in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2008; 27:588-96.
-
(2008)
Aliment Pharmacol Ther
, vol.27
, pp. 588-596
-
-
Noble, C.L.1
McCullough, J.2
Ho, W.3
-
13
-
-
33750356231
-
Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis
-
doi:10.1002/art.22117
-
Van Staa TP, Geusens P, Bijlsma JW et al. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 2006; 54:3104-12. doi:10.1002/art.22117
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3104-3112
-
-
Van Staa, T.P.1
Geusens, P.2
Bijlsma, J.W.3
-
14
-
-
0034469421
-
Mechanisms of bone loss in inflammatory arthritis: Diagnosis and therapeutic implications
-
doi:10.1186/ar67
-
Goldring SR, Gravallese EM. Mechanisms of bone loss in inflammatory arthritis: diagnosis and therapeutic implications. Arthritis Res 2000; 2:33-7. doi:10.1186/ar67
-
(2000)
Arthritis Res
, vol.2
, pp. 33-37
-
-
Goldring, S.R.1
Gravallese, E.M.2
-
15
-
-
0033581952
-
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
-
doi:10.1038/46303
-
Kong YY, Feige U, Sarosi I et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999; 402:304-9. doi:10.1038/46303
-
(1999)
Nature
, vol.402
, pp. 304-309
-
-
Kong, Y.Y.1
Feige, U.2
Sarosi, I.3
-
16
-
-
43949139580
-
Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial
-
doi:10.1002/art.23417
-
Cohen SB, Dore RK, Lane NE et al. Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial. Arth Rheum 2008; 58:1299-309. doi:10.1002/art.23417
-
(2008)
Arth Rheum
, vol.58
, pp. 1299-1309
-
-
Cohen, S.B.1
Dore, R.K.2
Lane, N.E.3
-
17
-
-
0036172368
-
Involvement of receptor activator of NFκB ligand and tumor necrosis factor-α in bone destruction in rheumatoid arthritis
-
doi:10.1016/S8756-3282(01) 00682-2
-
Romas E, Gillespie MT, Martin TJ. Involvement of receptor activator of NFκB ligand and tumor necrosis factor-α in bone destruction in rheumatoid arthritis. Bone 2002; 30:340-6. doi:10.1016/S8756-3282(01) 00682-2
-
(2002)
Bone
, vol.30
, pp. 340-346
-
-
Romas, E.1
Gillespie, M.T.2
Martin, T.J.3
-
18
-
-
16544369698
-
Imbalance of osteoclastogenesis- regulating factors in patients with celiac disease
-
doi:10.1359/JBMR.040319
-
Taranta A, Fortunati D, Longo M et al. Imbalance of osteoclastogenesis- regulating factors in patients with celiac disease. J Bone Miner Res 2004; 19:1112-21. doi:10.1359/JBMR.040319
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1112-1121
-
-
Taranta, A.1
Fortunati, D.2
Longo, M.3
-
19
-
-
0033304809
-
Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
-
doi:10.1210/en.140.10.4382
-
Hofbauer LC, Gori F, Riggs BL et al. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 1999; 140:4382-9. doi:10.1210/en.140.10.4382
-
(1999)
Endocrinology
, vol.140
, pp. 4382-4389
-
-
Hofbauer, L.C.1
Gori, F.2
Riggs, B.L.3
-
20
-
-
28544444640
-
Low bone density and low serum levels of soluble RANK ligand are associated with severe arterial calcification in patients with Takayasu arteritis
-
doi:10.1093/rheumatology/kei045
-
Bezerra MC, Calomeni GD, Caparbo VF et al. Low bone density and low serum levels of soluble RANK ligand are associated with severe arterial calcification in patients with Takayasu arteritis. Rheumatology 2005; 44:1503-6. doi:10.1093/rheumatology/kei045
-
(2005)
Rheumatology
, vol.44
, pp. 1503-1506
-
-
Bezerra, M.C.1
Calomeni, G.D.2
Caparbo, V.F.3
-
21
-
-
15444378849
-
The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss
-
doi:10.1136/gut.2004.044370
-
Moschen AR, Kaser A, Enrich B et al. The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss. Gut 2005; 54:479-87. doi:10.1136/gut.2004.044370
-
(2005)
Gut
, vol.54
, pp. 479-487
-
-
Moschen, A.R.1
Kaser, A.2
Enrich, B.3
-
22
-
-
27744599521
-
Circulating osteoprotegerin and receptor activator for nuclear factor κB ligand: Clinical utility in metabolic bone disease assessment
-
doi:10.1210/jc.2005-0794
-
Rogers A, Eastell R. Circulating osteoprotegerin and receptor activator for nuclear factor κB ligand: clinical utility in metabolic bone disease assessment. J Clin Endocrinol Metab 2005; 90:6323-31. doi:10.1210/jc.2005-0794
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 6323-6331
-
-
Rogers, A.1
Eastell, R.2
-
23
-
-
44449086365
-
Circulating RANKL is inversely related to RANKL mRNA levels in bone in osteoarthritic males
-
doi:10.1186/ar2348
-
Findlay D, Chehade M, Tsangari H et al. Circulating RANKL is inversely related to RANKL mRNA levels in bone in osteoarthritic males. Arthritis Res Ther 2008; 10:R2. doi:10.1186/ar2348
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Findlay, D.1
Chehade, M.2
Tsangari, H.3
-
24
-
-
0032954603
-
The epidemiology of Paget's disease in Britain: Is the prevalence decreasing?
-
doi:10.1359/jbmr.1999.14.2.192
-
Cooper C, Schafheutle K, Dennison E et al. The epidemiology of Paget's disease in Britain: is the prevalence decreasing? J Bone Miner Res 1999; 14:192-7. doi:10.1359/jbmr.1999.14.2.192
-
(1999)
J Bone Miner Res
, vol.14
, pp. 192-197
-
-
Cooper, C.1
Schafheutle, K.2
Dennison, E.3
-
25
-
-
25144442611
-
Genetics of Paget's disease of bone
-
doi:10.1042/CS20050053
-
Daroszewska A, Ralston SH. Genetics of Paget's disease of bone. Clin Sci (Lond) 2005; 109:257-63. doi:10.1042/CS20050053
-
(2005)
Clin Sci (Lond)
, vol.109
, pp. 257-263
-
-
Daroszewska, A.1
Ralston, S.H.2
-
26
-
-
0033987358
-
Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis
-
doi:10.1038/71667
-
Hughes AE, Ralston SH, Marken J et al. Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis. Nat Genet 2000; 24:45-8. doi:10.1038/71667
-
(2000)
Nat Genet
, vol.24
, pp. 45-48
-
-
Hughes, A.E.1
Ralston, S.H.2
Marken, J.3
-
27
-
-
0038643034
-
Phenotypic characterization of early onset Paget's disease of bone caused by a 27-bp duplication in the TNFRSF11A gene
-
doi:10.1359/jbmr.2003. 18.8.1381
-
Nakatsuka K, Nishizawa Y, Ralston SH. Phenotypic characterization of early onset Paget's disease of bone caused by a 27-bp duplication in the TNFRSF11A gene. J Bone Miner Res 2003; 18:1381-5. doi:10.1359/jbmr.2003. 18.8.1381
-
(2003)
J Bone Miner Res
, vol.18
, pp. 1381-1385
-
-
Nakatsuka, K.1
Nishizawa, Y.2
Ralston, S.H.3
-
28
-
-
0036133351
-
Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis
-
doi:10.1359/jbmr.2002.17.1.26
-
Whyte MP, Hughes AE. Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis. J Bone Miner Res 2002; 17:26-9. doi:10.1359/jbmr.2002.17.1.26
-
(2002)
J Bone Miner Res
, vol.17
, pp. 26-29
-
-
Whyte, M.P.1
Hughes, A.E.2
-
29
-
-
10744230044
-
Idiopathic hyperphosphatasia and TNFRSF11B mutations: Relationships between phenotype and genotype
-
doi:10.1359/jbmr.2003.18.12.2095
-
Chong B, Hegde M, Fawkner M et al. Idiopathic hyperphosphatasia and TNFRSF11B mutations: relationships between phenotype and genotype. J Bone Miner Res 2003; 18:2095-104. doi:10.1359/jbmr.2003.18.12.2095
-
(2003)
J Bone Miner Res
, vol.18
, pp. 2095-2104
-
-
Chong, B.1
Hegde, M.2
Fawkner, M.3
-
30
-
-
46749127771
-
Pathogenesis and management of Paget's disease of bone
-
doi:10.1016/S0140-6736(08) 61035-1
-
Ralston SH, Langston AL, Reid IR. Pathogenesis and management of Paget's disease of bone. Lancet 2008; 372:155-63. doi:10.1016/S0140-6736(08) 61035-1
-
(2008)
Lancet
, vol.372
, pp. 155-163
-
-
Ralston, S.H.1
Langston, A.L.2
Reid, I.R.3
-
31
-
-
70350646912
-
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
-
doi:10.1038/ng.446
-
Rivadeneira F, Styrkársdottir U, Estrada K et al. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009; 41:1199-206. doi:10.1038/ng.446
-
(2009)
Nat Genet
, vol.41
, pp. 1199-1206
-
-
Rivadeneira, F.1
Styrkársdottir, U.2
Estrada, K.3
-
32
-
-
0037292208
-
The effects of estrogen on osteoprotegerin, RANKL, and estrogen receptor expression in human osteoblasts
-
doi:10.1016/S8756-3282(02)00953-5
-
Bord S, Ireland DC, Beavan SR et al. The effects of estrogen on osteoprotegerin, RANKL, and estrogen receptor expression in human osteoblasts. Bone 2003; 32:136-41. doi:10.1016/S8756-3282(02)00953-5
-
(2003)
Bone
, vol.32
, pp. 136-141
-
-
Bord, S.1
Ireland, D.C.2
Beavan, S.R.3
-
33
-
-
0033026628
-
Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: Increased serum concentrations in postmenopausal women with osteoporosis
-
doi:10.1359/jbmr.1999.14.4.518
-
Yano K, Tsuda E, Washida N et al. Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: increased serum concentrations in postmenopausal women with osteoporosis. J Bone Miner Res 1999; 14:518-27. doi:10.1359/jbmr.1999.14.4.518
-
(1999)
J Bone Miner Res
, vol.14
, pp. 518-527
-
-
Yano, K.1
Tsuda, E.2
Washida, N.3
-
34
-
-
70349883835
-
Osteoporosis associated with neutralizing autoantibodies against osteoprotegerin
-
doi:10.1056/NEJMoa0810925
-
Riches PL, McRorie E, Fraser WD et al. Osteoporosis associated with neutralizing autoantibodies against osteoprotegerin. N Engl J Med 2009; 361:1459-65. doi:10.1056/NEJMoa0810925
-
(2009)
N Engl J Med
, vol.361
, pp. 1459-1465
-
-
Riches, P.L.1
McRorie, E.2
Fraser, W.D.3
-
35
-
-
0035139584
-
The effect of a single dose of osteoprotegerin in postmenopausal women
-
doi:10.1359/jbmr.2001.16.2.348
-
Bekker PJ, Holloway D, Nakanishi A et al. The effect of a single dose of osteoprotegerin in postmenopausal women. J Bone Miner Res 2001; 16:348-60. doi:10.1359/jbmr.2001.16.2.348
-
(2001)
J Bone Miner Res
, vol.16
, pp. 348-360
-
-
Bekker, P.J.1
Holloway, D.2
Nakanishi, A.3
-
36
-
-
69049083492
-
Denosumab for prevention of fractures in postmenopausal women with osteoporosis
-
doi:10.1056/NEJMoa0809493
-
Cummings SR, Martin JS, McClung MR et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 2009; 361:756-65. doi:10.1056/NEJMoa0809493
-
(2009)
N Engl J Med
, vol.361
, pp. 756-765
-
-
Cummings, S.R.1
Martin, J.S.2
McClung, M.R.3
-
37
-
-
27744586067
-
Small-molecule inhibition of TNF-α
-
doi:10.1126/science.1116304
-
He MM, Smith AS, Oslob JD et al. Small-molecule inhibition of TNF-α. Science 2005; 310:1022-5. doi:10.1126/science.1116304
-
(2005)
Science
, vol.310
, pp. 1022-1025
-
-
He, M.M.1
Smith, A.S.2
Oslob, J.D.3
-
38
-
-
51349111243
-
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance
-
doi:10.1016/j.immuni.2008.06.015
-
Akiyama T, Shimo Y, Yanai H et al. The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity 2008; 29:423-37. doi:10.1016/j.immuni.2008.06.015
-
(2008)
Immunity
, vol.29
, pp. 423-437
-
-
Akiyama, T.1
Shimo, Y.2
Yanai, H.3
-
39
-
-
70849096810
-
Central control of fever and female body temperature by RANKL/RANK
-
doi:10.1038/nature08596
-
Hanada R, Leibbrandt A, Hanada T et al. Central control of fever and female body temperature by RANKL/RANK. Nature 2009; 462:505-9. doi:10.1038/nature08596
-
(2009)
Nature
, vol.462
, pp. 505-509
-
-
Hanada, R.1
Leibbrandt, A.2
Hanada, T.3
|