Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 7, 2010, Pages 2200-2203

  Bruyère, Hélène ^a   Westwell, Andrew D ^a   Jones, Arwyn T ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Drug delivery; Orthoester; pH sensitive linkers

Indexed keywords

ESTER DERIVATIVE;

ACIDIFICATION; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; ENDOCYTOSIS; HYDROLYSIS; PH; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE;

DRUG CARRIERS; ESTERS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS;

EID: 77949492875     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.02.035     Document Type: Article

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