Effects of Cytochrome P450 Inhibition by Cimetidine on the Warm Hepatic Ischemia-Reperfusion Injury in Rats

Journal of Surgical Research

Volumn 159, Issue 2, 2010, Pages 680-688

  Shaik, Imam H ^a   Mehvar, Reza ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

cimetidine; CYP2C11; cytochrome P450; ischemia reperfusion injury; isolated rat liver perfusion; P450 inhibition; ranitidine; reactive oxygen species

Indexed keywords

BIOCHEMICAL MARKER; BUFFER; CIMETIDINE; CYTOCHROME P450; CYTOCHROME P450 2C11; GLUTATHIONE; LIPID HYDROPEROXIDE; LIVER ENZYME; RANITIDINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; BILIARY EXCRETION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; EX VIVO STUDY; IN VIVO STUDY; LIVER; LIVER ISCHEMIA; LIVER PERFUSION; LIVER PROTECTION; MALE; MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; REPERFUSION INJURY; SHAM PROCEDURE; SINGLE DRUG DOSE; WARM HEPATIC ISCHEMIA REPERFUSION INJURY;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CATALASE; CIMETIDINE; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; L-LACTATE DEHYDROGENASE; LIPID PEROXIDES; LIVER; MALONDIALDEHYDE; MICROSOMES, LIVER; RABBITS; RANITIDINE; RATS; REPERFUSION INJURY; SUPEROXIDE DISMUTASE;

EID: 77949485627     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.09.016     Document Type: Article

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