In vitro verification of a 3-d regenerative neural interface design: Examination of neurite growth and electrical properties within a bifurcating microchannel structure

Proceedings of the IEEE

Volumn 98, Issue 3, 2010, Pages 389-397

  Wieringa, P A ^a   Wiertz, R W F ^a   De Weerd, E L ^a   Rutten, W L C ^a  

^a UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Biomedical engineering; Cellular engineering; Guidance scaffold; Neurite guiding; Peripheral neuroprosthesis; Regenerative neural interface; Selectivity; Tissue engineering

Indexed keywords

BIFURCATION (MATHEMATICS); BIOMEDICAL ENGINEERING; CATALYST SELECTIVITY; ELECTRODES; INTERFACES (COMPUTER); NEURAL PROSTHESES; NEURONS; NEUROSURGERY; SCAFFOLDS (BIOLOGY); SEPARATION; SIGNAL TO NOISE RATIO; TISSUE ENGINEERING;

ACTION POTENTIAL PROPAGATION; CELLULAR ENGINEERING; EXTRACELLULAR SIGNALS; NEURAL INTERFACES; NEURITES; NEURO-PROSTHESIS; PERIPHERAL NERVOUS SYSTEM; SEPARATION CHARACTERISTICS;

MICROCHANNELS;

EID: 77949424991     PISSN: 00189219     EISSN: None     Source Type: Journal    
DOI: 10.1109/JPROC.2009.2038950     Document Type: Article

References (20)

1. C. Ide, "Peripheral nerve regeneration," Neurosci. Res., vol.25, no.2, pp. 101-121, Jun. 1996.
2. X. Navarro, T. B. Krueger, N. Lago, S. Micera, T. Stieglitz, and P. Dario, "A critical review of interfaces with the peripheral nervous system for the control of neuroprostheses and hybrid bionic systems," J. Peripheral Nervous Syst., vol.10, pp. 229-258, 2005.
3. W. L. C. Rutten, "Selective electrical interfaces with the nervous system.," Annu. Rev. Biomed. Eng., vol.4, pp. 407-452, 2002.
4. D. J. Edell, V. Van Toi, V. M. McNeil, and L. D. Clark, "Factors influencing the biocompatibility of insertable silicon microshafts," IEEE Trans. Biomed. Eng., vol.39, no.6, pp. 635-643, Jun. 1992.
5. N. Lago, E. Udina, A. Ramachandran, and X. Navarro, "Neurobiological assessment of regenerative electrodes for bidirectional interfacing injured peripheral nerves," IEEE Trans. Biomed. Eng., vol.54, no.6, pp. 1129-1137, Jun. 2007.
6. J. J. Fitzgerald, S. P. Lacour, S. B. McMahon, and J. W. Fawcett, "Microchannels as axonal amplifiers," IEEE Trans. Biomed. Eng., vol.55, no.3, pp. 1136-1146, Mar. 2008.
7. R. Morales, M. Riss, L. Wang, R. Gav́in, J. A. Del Ŕio, R. Alcubilla, and E. Claverol-Tintuŕe, "Integrating multi-unit electrophysiology and plastic culture dishes for network neuroscience.," Lab on a Chip, vol.8, pp. 1896-1905, 2008.
8. B. J. Dworak and B. C. Wheeler, "Novel MEA platform with PDMS microtunnels enables the detection of action potential propagation from isolated axons in culture," Lab on a Chip, vol.9, p. 404, 2009.
9. J. W. Park, B. Vahidi, A. M. Taylor, S. W. Rhee, and N. L. Jeon, "Microfluidic culture platform for neuroscience research," Nat. Protocols, vol.1, pp. 2128-2136, Dec. 2006.
10. E. Claverol-Tintuŕe, J. Cabestany, and X. Rosell, "Multisite recording of extracellular potentials produced by microchannel-confined neurons in-vitro," IEEE Trans. Biomed. Eng., vol.54, no.2, pp. 331-335, Feb. 2007.
11. F. Morin, N. Nishimura, L. Griscom, B. Lepioufle, H. Fujita, Y. Takamura, and E. Tamiya, "Constraining the connectivity of neuronal networks cultured on microelectrode arrays with microfluidic techniques: A step towards neuron-based functional chips," Biosens. Bioelectron., vol.21, pp. 1093-1100, 2006.
12. A. R. Vancha, S. Govindaraju, K. V. L. Parsa, M. Jasti, M. Gonźalez-Garćia, and R. P. Ballestero, "Use of polyethyleneimine polymer in cell culture as attachment factor and lipofection enhancer," BMC Biotechnol., vol.4, p. 23, Oct. 2004.
13. J. C. McDonald, D. C. Duffy, J. R. Anderson, D. T. Chiu, H. Wu, O. J. Schueller, and G. M. Whitesides, "Fabrication of microfluidic systems in poly(dimethylsiloxane)," ElectrophoResis, vol.21, no.1, pp. 27-40, Jan. 2000.
14. M. P. Maher, J. Pine, J. Wright, and Y. C. Tai, "The neurochip: A new multielectrode device for stimulating and recording from cultured neurons," J Neurosci. Methods, vol.87, no.1, pp. 45-56, Feb. 1999.
15. H. J. Romijn, F. Van Huizen, and P. S. Wolters, "Towards an improved serum-free, chemically defined medium for long-term culturing of cerebral cortex tissue," Neurosci. Biobehav. Rev., vol.8, no.3, pp. 301-334, 1984.
16. W. S. Rasband. (2009). ImageJ, NIH, "ethesda, MD. [Online]. Available: http://rsb.info.nih.gov/ij/
17. A. Cardona and R. Douglas. (2008). TrakEm2, Institute of Neuroinformatics, Zurich. [Online]. Available: http://www.ini.uzh.ch/~acardona/ trakem2.html
18. E. Meijerink. (2008). MTrackJ, Erasmus MC, Rotterdam. [Online]. Available: http://www.imagescience.org/meijering/software/
19. A. Lee. (2008). VirtualDub. [Online]. Available: http://www.virtualdub. org/
20. J. B. Colombe and P. S. Ulinski, "Temporal dispersion windows in cortical neurons,[J. Comput. Neurosci., vol. 7, pp. 71-87,1999.