The effect of food consumption on lumefantrine bioavailability in African children receiving artemether-lumefantrine crushed or dispersible tablets (Coartem®) for acute uncomplicated Plasmodium falciparum malaria

Tropical Medicine and International Health

Volumn 15, Issue 4, 2010, Pages 434-441

  Borrmann, Steffen ^a,b   Sallas, William M ^c   Machevo, Sonia ^d   González, Raquel ^d,e   Björkman, Anders ^f   Mårtensson, Andreas ^f,g   Hamel, Mary ^b   Juma, Elizabeth ^b   Peshu, Judy ^b   Ogutu, Bernhards ^b   Djimdé, Abdoulaye ^h   D'Alessandro, Umberto ⁱ   Marrast, Anne Claire ^c   Lefèvre, Gilbert ^c   Kern, Steven E ^c,j  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c NOVARTIS PHARMA AG   (Switzerland)

^d Ministérioda Saúde   (Mozambique)

^e CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^g KAROLINSKA INSTITUTE   (Sweden)

^h UNIVERSITY OF BAMAKO   (Mali)

ⁱ INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^j UNIVERSITY OF UTAH   (United States)

more..

Author keywords

Artemether; Bioavailability; Coartem; Food; Lumefantrine; Pharmacokinetics

Indexed keywords

ARTEMETHER PLUS BENFLUMETOL; BENFLUMETOL;

ABSORPTION; BIOAVAILABILITY; BLOOD; CHILD HEALTH; FOOD CONSUMPTION; FOOD INTAKE; MALARIA; PLASMA; POLYMERASE CHAIN REACTION; PROTIST;

ACUTE DISEASE; AFRICA; ARTICLE; BLOOD SAMPLING; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISPERSIBLE TABLET; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFICACY; FEMALE; FOOD; FOOD DRUG INTERACTION; FOOD INTAKE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MILK; MULTICENTER STUDY; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SINGLE BLIND PROCEDURE;

ACUTE DISEASE; AFRICA; ANTIMALARIALS; ARTEMISININS; BIOLOGICAL AVAILABILITY; CHILD; CHILD, PRESCHOOL; DIET; DRUG COMBINATIONS; ETHANOLAMINES; FEMALE; FLUORENES; FOOD-DRUG INTERACTIONS; HUMANS; MALARIA, FALCIPARUM; MALE; TIME FACTORS;

AFRICA;

PLASMODIUM FALCIPARUM;

EID: 77949421403     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/j.1365-3156.2010.02477.x     Document Type: Article

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