Midkine gene transfer after myocardial infarction in rats prevents remodelling and ameliorates cardiac dysfunction

Cardiovascular Research

Volumn 86, Issue 1, 2010, Pages 113-121

  Sumida, Arihiro ^a   Horiba, Mitsuru ^a   Ishiguro, Hisaaki ^a,b   Takenaka, Hiroharu ^a,b   Ueda, Norihiro ^a   Ooboshi, Hiroaki ^c   Opthof, Tobias ^d,e   Kadomatsu, Kenji ^b   Kodama, Itsuo ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Coronary disease; Gene transfer; Haemodynamics; Infarction; Remodelling

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; MIDKINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DOWN REGULATION; ECHOCARDIOGRAPHY; EXPERIMENTAL RAT; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; HEART FAILURE; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE FIBROSIS; HEART MUSCLE ISCHEMIA; HEART VENTRICLE REMODELING; HEART WEIGHT; HEMODYNAMICS; HISTOLOGY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REPERFUSION; SHAM PROCEDURE; UPREGULATION; VIRUS GENE; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOVIRIDAE; ANIMALS; APOPTOSIS; COLLAGEN TYPE I; COLLAGEN TYPE III; CYTOKINES; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEMODYNAMICS; INJECTIONS, INTRALESIONAL; LAC OPERON; MALE; MICE; MYOCARDIAL INFARCTION; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 77949419010     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp386     Document Type: Article

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