P2Y4-mediated regulation of Na+ absorption in the Reissner's membrane of the cochlea

Journal of Neuroscience

Volumn 30, Issue 10, 2010, Pages 3762-3769

  Kim, Chang Hee ^a   Kim, Hye Young ^a   Lee, Ho Sun ^a   Chang, Sun O ^a   Oh, Seung Ha ^a   Lee, Jun Ho ^a  

^a Seoul National University Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 [6[[(17BETA) 3 METHOXYESTRA 1,3,59(10) TRIEN 17 YL]AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 O OCTADECYL 2 O METHYL RAC GLYCERO 3 2 AMINOEHOXYDIPHENYL BORATE; 4' DISULFONIC ACID; BLUE 2 AND 2',3' O (4 BENZOYLBENZOYL)ADENOSINE 5' TRIPHOSPHATE; EPITHELIAL SODIUM CHANNEL; PHOSPHATE; PHOSPHOLIPASE C INHIBITOR; PURINERGIC P2Y4 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SULFONIC ACID DERIVATIVE; SURAMIN; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE; PURINERGIC P2 RECEPTOR; SODIUM;

ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CELL MEMBRANE; COCHLEA; CORTI ORGAN; ENDOLYMPH; EPITHELIUM CELL; HAIR CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REISSNER MEMBRANE; SODIUM ABSORPTION; STRIA VASCULARIS; VESTIBULE; ABSORPTION; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; GERBIL; METABOLISM; PHYSIOLOGY;

ABSORPTION; ANIMALS; COCHLEA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOLYMPH; EPITHELIAL CELLS; EPITHELIAL SODIUM CHANNEL; GERBILLINAE; RECEPTORS, PURINERGIC P2; SODIUM; URIDINE TRIPHOSPHATE;

EID: 77949403654     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3300-09.2010     Document Type: Article

References (55)

1. Bogdanov YD, Wildman SS, Clements MP, King BF, Burnstock G (1998) Molecular cloning and characterization of rat P2Y4 nucleotide receptor. Br J Pharmacol 124:428-430.
2. Booth RE, Stockand JD (2003) Targeted degradation of ENaC in response to PKC activation of the ERK1/2 cascade. Am J Physiol Renal Physiol 284:F938 -F947.
3. + release. FASEB J 16:1145-1150.
4. Couloigner V, Fay M, Djelidi S, Farman N, Escoubet B, Runembert I, Sterkers O, Friedlander G, Ferrary E (2001) Location and function of the epithelial Na channel in the cochlea. Am J Physiol Renal Physiol 280:F214 -F222.
5. + absorption in M-1 mouse cortical collecting duct cells. J Physiol 524:77-90.
6. + absorption in wild-type and DeltaF508 CFTR-expressing human bronchial epithelia. Am J Physiol 276:C827-C837.
7. Garty H, Palmer LG (1997) Epithelial sodium channels: function, structure, and regulation. Physiol Rev 77:359 -396.
8. Hilgemann DW, Feng S, Nasuhoglu C (2001) The complex and intriguing lives of PIP2 with ion channels and transporters. Sci STKE 2001:re19.
9. Homolya L, Steinberg TH, Boucher RC (2000) Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia. J Cell Biol 150:1349 -1360.
10. Housley GD (1998) Extracellular nucleotide signaling in the inner ear. Mol Neurobiol 16:21- 48.
11. Housley GD, Luo L, Ryan AF (1998) Localization of mRNA encoding the P2X2 receptor subunit of the adenosine 5′-triphosphate-gated ion channel in the adult and developing rat inner ear by in situ hybridization. J Comp Neurol 393:403- 414.
12. Housley GD, Jagger DJ, Greenwood D, Raybould NP, Salih SG, Järlebark LE, Vlajkovic SM, Kanjhan R, Nikolic P, Muñoz DJ, Thorne PR (2002) Purinergic regulation of sound transduction and auditory neurotransmission. Audiol Neurootol 7:55- 61.
13. + absorption in distal bronchi. Pflugers Arch 438:621- 627.
14. +-ATPase alpha-subunit in the lateral wall of rat cochlear duct. J Histochem Cytochem 37:353-363.
15. Kim CH, Kim HY, Chang SO, Oh SH, Lee JH (2009a) P2Y4 receptor-mediated regulation of amiloride-sensitive sodium transport in the Reissner's membrane of gerbil cochlea. Presented at the 32nd Midwinter Meeting of the Association for Research in Otolaryngology, Baltimore, February 14-19.
16. +-absorptive function in Reissner's membrane epithelia. Neuroreport 20:1275-1278.
17. Kim SH, Kim KX, Raveendran NN,WuT, Pondugula SR, MarcusDC (2009) Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium. Am J Physiol Cell Physiol 296:C544-C557.
18. King M, Housley GD, Raybould NP, Greenwood D, Salih SG (1998) Expression of ATP-gated ion channels by Reissner's membrane epithelial cells. Neuroreport 9:2467-2474.
19. + transport via hydrolysis of PIP2. FASEB J 19:142-143.
20. Lazarowski ER, Homolya L, Boucher RC, Harden TK (1997) Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. J Biol Chem 272:24348 -24354.
21. Lee JH, Marcus DC (2003) Endolymphatic sodium homeostasis by Reissner's membrane. Neuroscience 119:3- 8.
22. Lee JH, Marcus DC (2008) Purinergic signaling in the inner ear. Hear Res 235:1-7.
23. 2 receptor mediates stimulation of parasensory cation absorption by cochlear outer sulcus cells and vestibular transitional cells. J Neurosci 21:9168 -9174.
24. + absorption in isolated perfused mouse CCD. J Am Soc Nephrol 13:10 -18.
25. Leipziger J (2003) Control of epithelial transport via luminal P2 receptors. Am J Physiol Renal Physiol 284:F419 -F432.
26. + channels. EMBO J 22:5412-5421.
27. Ma HP, Chou CF, Wei SP, Eaton DC (2007) Regulation of the epithelial sodium channel by phosphatidylinositides: experiments, implications, and speculations. Pflugers Arch 455:169 -180.
28. + absorption by extracellular nucleotides in human normal and cystic fibrosis airways.AmJ Respir Cell Mol Biol 23:755-761.
29. Marcus DC (1996) Vibrating probes: new technology for investigation of endolymph homeostasis. Keio J Med 45:301-305.
30. + absorption by outer sulcus epithelial cells. Hear Res 134:48 -56.
31. + secretion by vestibular dark cell epithelium.AmJ Physiol Cell Physiol 281:C282-C289.
32. Marcus DC, Shipley AM (1994) Potassium secretion by vestibular dark cell epithelium demonstrated by vibrating probe. Biophys J 66:1939 -1942.
33. Marcus DC, Sunose H, Liu J, Bennett T, Shen Z, Scofield MA, Ryan AF (1998) Protein kinase C mediates P2U purinergic receptor inhibition of K+ channel in apical membrane of strial marginal cells. Hear Res 115:82-92.
34. + secretion by strial marginal cell epithelium. Cell Commun Signal 3:13.
35. 2 receptors. Pflugers Arch 454:977-987.
36. + channel-like immunoreactivity in the luminal membrane of some non-sensory epithelia of the inner ear. Hear Res 88:199 -205.
37. Muñoz DJ, Kendrick IS, Rassam M, Thorne PR (2001) Vesicular storage of adenosine triphosphate in the guinea-pig cochlear lateral wall and concentrations of ATP in the endolymph during sound exposure and hypoxia. Acta Otolaryngol 121:10 -15.
38. Parker MS, Onyenekwu NN, Bobbin RP (2003) Localization of the P2Y4 receptor in the guinea pig organ of Corti. J Am Acad Audiol 14:286 -295.
39. Pochynyuk O, Bugaj V, Vandewalle A, Stockand JD (2008) Purinergic control of apical plasma membrane PI(4,5)P2 levels sets ENaC activity in principal cells. Am J Physiol Renal Physiol 294:F38 -F46.
40. Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413- 492.
41. Robaye B, Boeynaems JM, Communi D (1997) Slow desensitization of the human P2Y6 receptor. Eur J Pharmacol 329:231-236.
42. Sage CL, Marcus DC (2002) Immunolocalization of P2Y4 and P2Y2 purinergic receptors in strial marginal cells and vestibular dark cells. J Membr Biol 185:103-115.
43. + channel subunit proteins. J Biol Chem 275:25760 -25765.
44. Szücs A, Szappanos H, Tóth A, Farkas Z, Panyi G, Csernoch L, Sziklai I (2004) Differential expression of purinergic receptor subtypes in the outer hair cells of the guinea pig. Hear Res 196:2-7.
45. Tao L, Harris AL (2007) 2-aminoethoxydiphenyl borate directly inhibits channels composed of connexin26 and/or connexin32. Mol Pharmacol 71:570 -579.
46. 2 receptormediated inhibition of amiloride-sensitive short circuit current in M-1 mouse cortical collecting duct cells. J Membr Biol 183:115-124.
47. von Kügelgen I (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol Ther 110:415- 432.
48. + cycling and its regulation in the cochlea and the vestibular labyrinth. Audiol Neurootol 7:199 -205.
49. 2+ ions. Br J Pharmacol 140:1177-1186.
50. Xu SZ, Zeng F, Boulay G, Grimm C, Harteneck C, Beech DJ (2005) Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect. Br J Pharmacol 145:405- 414.
51. Yamamoto T, Suzuki Y (2002) Role of luminal ATP in regulating electrogenic Na+ absorption in guinea pig distal colon. Am J Physiol Gastrointest Liver Physiol 283:G300-G308.
52. + channels in apical membrane of epithelial cells of Reissner's membrane. Hear Res 109:1-10.
53. Yeh TH, Herman P, Tsai MC, Tran Ba Huy P, Van den Abbeele T (1998) A cationic nonselective stretch-activated channel in the Reissner's membrane of the guinea pig cochlea. Am J Physiol 274:C566 -C576.
54. Zdebik AA, Wangemann P, Jentsch TJ (2009) Potassium ion movement in the inner ear: insights from genetic disease and mouse models. Physiology (Bethesda) 24:307-316.
55. Zhong SX, Liu ZH (2004) Immunohistochemical localization of the epithelial sodium channel in the rat inner ear. Hear Res 193:1- 8.