DNA modifications by the ù-3 lipid peroxidation-derived mutagen 4-Oxo-2-hexenal in vitro and their analysis in mouse and human DNA

Chemical Research in Toxicology

Volumn 23, Issue 3, 2010, Pages 630-636

  Kawai, Kazuaki ^a   Chou, Pei Hsin ^b   Matsuda, Tomonari ^b   Inoue, Masaaki ^c   Aaltonen, Kaisa ^d   Savela, Kirsti ^d   Takahashi, Yoshikazu ^e   Nakamura, Hikaru ^e   Kimura, Tomoyuki ^e   Watanabe, Takumi ^e   Sawa, Ryuichi ^e   Dobashi, Kazuyuki ^f   Li, Yun Shan ^a   Kasai, Hiroshi ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c Japan Organization of Occupational Health and Safety   (Japan)

^d NATL VET AND FOOD RES INSTITUTE   (Finland)

^e INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^f Japan Bioindustry Association   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 OXO 2 HEXENAL; 5 METHYLDEOXYCYTIDINE; DEOXYADENOSINE; DEOXYCYTIDINE; OMEGA 3 FATTY ACID; UNCLASSIFIED DRUG; 4 OXO (E) 2 HEXENAL; 4-OXO-(E)-2-HEXENAL; ALDEHYDE; CALF THYMUS DNA; DNA; MUTAGENIC AGENT;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DETERMINATION; DNA MODIFICATION; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INTESTINE; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY; LUNG; MALE; MOUSE; NONHUMAN; REFERENCE VALUE; SMOKING; STOMACH; TANDEM MASS SPECTROMETRY; ANIMAL; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

BRASSICA NAPUS; GLYCINE MAX; MUS; PERILLA;

ALDEHYDES; ANIMALS; CATTLE; DNA; DNA ADDUCTS; FEMALE; HUMANS; LIPID PEROXIDATION; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; MUTAGENS; NUCLEIC ACID CONFORMATION;

EID: 77949402000     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx9003819     Document Type: Article

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