Virulence factor-activity relationships (VFAR) with specific emphasis on Aeromonas species (spp.)

Journal of Water and Health

Volumn 7, Issue SUPPL. 1, 2009, Pages

  Chopra, Ashok K ^a   Graf, Joerg ^b   Horneman, Amy J ^c   Johnson, Judith A ^d,e  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MARYLAND   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

Aeromonas species; Animal models; Epidemiology; Gastroenteritis; Septicemia; Virulence factors

Indexed keywords

AEROLYSIN; ARACHIDONIC ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENTEROTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; VIRULENCE FACTOR;

BACTERIUM; DIARRHEAL DISEASE; EPIDEMIOLOGY; FOOD CONSUMPTION; GASTROENTERITIS; HURRICANE KATRINA 2005; HYBRIDIZATION; IMMUNE SYSTEM; PATHOGEN; PUBLIC HEALTH; VIRULENCE; WATER USE;

AEROMONAS; AEROMONAS HYDROPHILA; BACTERIUM ADHERENCE; BACTERIUM ISOLATE; DIARRHEA; GASTROENTERITIS; GENE CONTROL; HUMAN; HURRICANE; NONHUMAN; PATHOGENESIS; REVIEW; SECRETION; STRUCTURE ACTIVITY RELATION; TSUNAMI;

AEROMONAS; BIOLOGICAL MARKERS; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; VIRULENCE; VIRULENCE FACTORS; WATER MICROBIOLOGY;

LOUISIANA; NEW ORLEANS; THAILAND; UNITED STATES;

AEROMONAS; AEROMONAS HYDROPHILA; AEROMONAS VERONII; ANIMALIA;

EID: 77949374878     PISSN: 14778920     EISSN: None     Source Type: Journal    
DOI: 10.2166/wh.2009.053     Document Type: Review

References (213)

1. Abbot, S. L., Seli, L. S., Catino, M. J., Hartley, M. A. & Janda, J. M. 1998 Misidentification of unusual Aeromonas species as members of the genus Vibrio: a continuing problem. J. Clin. Microbiol. 36, 1103-1104.
2. Agger, W. A. 1986 Diarrhea associated with Aeromonas hydrophila. Pediatr. Infect. Dis. 5, 5106-5108.
3. Aguillar, A., Marino, S., Nogueras, M. M., Regue, M. & Tomas, J. M. 1999 Two genes from the capsule of Aeromonas hydrophila (serogroup O:34) confer serum resistance to Escherichia coli strains. Res. Microbiol. 150, 395-402.
4. Ahmed, A., Hafiz, S., Zafar, A., Shamsi, T., Rizvi, J. & Syed, S. 1997 Isolation and identification of Aeromonas species from human stools. J. Pak. Med. Assoc. 47, 305-308.
5. Alavandi, S. V., Subashmi, M. S. & Ananthan, S. 1999 Occurence of haemolytic and cytotoxic Aeromonas species in domestic water supplies in Chennai. Ind. J. Med. Res. 110, 50-55.
6. Albert, M. J., Ansaruzzaman, M., Talukder, K. A., Chopra, A. K., Kuhn, I., Rahman, M., Faruque, A. S. G., Islam, M. S., Sack, R. B. & Mollby, R. 2000 Prevalence of enterotoxin genes in Aeromonas spp. isolated from children with diarrhea, healthy controls, and the environment. J. Clin. Microbiol. 38, 3785-3790.
7. Altwegg, M. 1985 Aeromonas caviae: an enteric pathogen? Infection 13, 228-230.
8. Altwegg, M., Lucchini, G. M., Luthy-Hottenstein, J. & Rohrbach, M. 1991 Aeromonas-associated gastroenteritis after consumption of contaminated shrimp. Eur. J. Clin. Microbiol. Infect. Dis. 10, 44-45.
9. Annapurna, E. & Sanyal, S. C. 1977 Enterotoxicity of Aeromonas hydrophila. J. Med. Microbiol. 10, 317-323.
10. Asao, T. A., Kinoshita, Y., Kozaki, S., Vemura, T. & Sakaguchi, G. 1984 Purification and some properties of Aeromonas hydrophila hemolysin. Infect. Immun. 46, 122-127.
11. Ascencio, F., Martinez-Arias, W., Romero, M. J. & Wadstrom, T. 1998 Analysis of the interaction of Aeromonas caviae, A. hydrophila and A. sobria with mucins. FEMS Immun. Med. Microbiol. 20, 219-229.
12. Atkinson, H. M. & Trust, T. J. 1980 Hemagglutination properties and adherence ability of Aeromonas hydrophila. Infect. Immun. 27, 938-946.
13. Barnett, T. C., Kirov, S. M., Strom, M. S. & Sanderson, K. 1997 Aeromonas spp. possess at least two distinct type IV pilus families. Microb. Pathog. 23, 241-247.
14. Bartlett, D. H., Frantz, B. B. & Matsumura, P. 1988 Flagellar transcriptional activators F1bB and F1aI: gene sequence and 5′ consensus sequence of operons under F1bB and F1aI control. J. Bacteriol. 170, 1575-1581.
15. Bernheimer, A. W., Avigad, L. S. & Avigad, G. 1975 Interactions between aerolysin, erythrocytes, and erythrocyte membranes. Infect. Immun. 11, 1312-1319.
16. Borczyk, A., McLeod, S., Riley, G. & Lior, H. 1993 Isolation of Aeromonas species from diarrheal cases in Ontario, Canada. In: 4th International Symposium on Aeromonas and Plesiomonas. Atlanta, GA.
17. Borrell, N., Figueras, M. J. & Guarro, J. 1998 Phenotypic identification of Aeromonas genomospecies from clinical and environmental sources. Can. J. Microbiol. 44, 103-108.
18. Boyd, J. M., Dacanay, A., Knickle, L. C., Touhami, A., Brown, L. L., Jericho, M. H., Johnson, S. C. & Reith, M. 2008 Contribution of type IV pili to the virulence of Aeromonas salmonicida subsp. salmonicida in Atlantic salmon (Salmo salar L.). Infect. Immun. 76, 1445-1455.
19. Brandi, G., Sisti, M., Giardini, F., Schiavano, G. F. & Albano, A. 1999 Survival ability of cytotoxic strains of motile Aeromonas spp. in different types of water. Lett. Appl. Microbiol. 29, 211-215.
20. Braschler, T. R., Merino, S., Tomas, J. M. & Graf, J. 2003 Complement resistance is essential for colonization of the digestive tract of Hirudo medicinalis by Aeromonas strains. Appl. Environ. Microbiol. 69, 4268-4271.
21. Buchanan, R. L. & Palumbo, S. A. 1985 Aeromonas hydrophila and Aeromonas sobria as potential food poisoning species: a review. J. Food Saf. 7, 15-29.
22. Burke, V., Gracey, M., Robinson, J., Peck, D., Beaman, J. & Bundell, C. 1983 The microbiology of childhood gastroenteritis: Aeromonas species and other infective agents. J. Infect. Dis. 148, 68-74.
23. Burr, S. E., Stuber, K., Wahli, T. & Frey, J. 2002 Evidence for a type III secretion system in Aeromonas salmonicida subsp. salmonicida. J. Bacteriol. 184, 5966-5970.
24. Burr, S. E., Stuber, K. & Frey, J. 2003 The ADP-ribosylating toxin, AexT, from Aeromonas salmonicida subsp. salmonicida is translocated via a type III secretion pathway. J. Bacteriol. 185, 6583-6591.
25. Byers, B. R., Massad, G., Barghouthi, S. & Arceneaux, J. E. L. 1991 Iron acquisition and virulence in the motile aeromonads: siderophore-dependent and-independent systems. Experientia 47, 416-418.
26. Callister, S. M. & Agger, W. A. 1987 Enumeration and characterization of Aeromonas hydrophila and Aeromonas caviae isolated from grocery store produce. Appl. Environ. Microbiol. 53, 249-253.
27. Carlos, G. -R., Concha, C. & Krovacek, K. 2002 Bovine mastitis caused by Aeromonas hydrophila in Sweden. In: Seventh International Symposium on Aeromonas and Plesiomonas, Orihuela (Alicante), Spain. Blackwell Publishing Ltd., Oxford, England, p. 52.
28. Carnahan, A. M. 1993 Aeromonas taxonomy: a sea of change. Med. Microbiol. Lett. 2, 206-211.
29. Carnahan, A. M. & Altwegg, M. 1996 Taxonomy. In The Genus Aeromonas (ed. B. Austin, M. Altwegg, P. J. Gosling & S. Joseph), pp. 1-38. John Wiley & Sons, New York, NY.
30. Carnahan, A. M. & Joseph, S. W. 1991 Aeromonas update: new species and global distribution. Experientia 47, 402-403.
31. Carnahan, A. M., Marii, M. A., Fanning, G. R., Verma, D., Ali, A., Janda, J. M. & Joseph, S. W. 1989 Characterization of Aeromonas schubertii strains recently isolated from traumatic wound infections. J. Clin. Microbiol. 27, 1826-1830.
32. Carnahan-Martin, A. & Joseph, S. W. 2005 Aeromonadaceae. In The Proteobacteria, Part B, Bergey's Manual of Systematic Bacteriology, (ed. D. J. Brenner, N. R. Kreig, J. T. Staley & G. M. Garrity), 2nd edition. Vol. 2, pp. 581-586. Springer-Verlag, New York.
33. Chacon, M. R., Solar, L., Groisman, E. A., Guarro, J. & Figueras, M. J. 2004 Type III secretion system genes in clinical Aeromonas isolates. J. Clin. Microbiol. 42, 1285-1287.
34. Chakraborty, T., Montenegro, M. A., Sanyal, S. C., Helmuth, R., Bulling, E. & Timmis, K. N. 1984 Cloning of enterotoxin gene from Aeromonas hydrophila provides conclusive evidence of production of a cytotonic enterotoxin. Infect. Immun. 46, 435-441.
35. Chakraborty, T., Huhle, B., Bergbauer, H. & Goebel, W. 1986 Cloning, expression, and mapping of the Aeromonas hydrophila aerolysin gene determinant in Escherichia coli K-12. J. Bacteriol. 167, 368-374.
36. Chakraborty, T., Huhle, B., Hof, H., Bergbauer, H. & Goebel, W. 1987 Marker exchange mutagenesis of the aerolysin determinant in Aeromonas hydrophila demonstrates the role of aerolysin in A. hydrophila associated systemic infections. Infect. Immun. 55, 2274-2280.
37. Chakraborty, T., Husslein, V., Huhle, B., Bergbauer, H., Jarchau, T. & Hof, H. 1988 Bacterial protein toxins. Zbl. Bakt. Suppl. 17, 215-222.
38. Challapalli, M., Tess, B. R., Cunningham, D. G., Chopra, A. K. & Houston, C. W. 1988 Aeromonas-associated diarrhea in children. Pediatr. Infect. Dis. J. 7, 693-698.
39. Chatterjee, B. D. & Neogy, K. N. 1972 Studies on Aeromonas and Plesiomomas species isolated from cases of choleric diarrhea. Ind. J. Med. Res. 60, 520-524.
40. Chauret, C., Volk, C., Creason, R., Jarosh, J., Robinson, J. & Warnes, C. 2001 Detection of Aeromonas hydrophila in a drinking-water distribution system: a field and pilot study. Can. J. Microbiol. 47, 782-786.
41. Cheng, N. C., Horng, S. Y., Chang, S. C. & Tang, Y. B. 2004 Nosocomial infection of Aeromonas hydrophila presenting as necrotizing fasciitis. J. Formos. Med. Assoc. 103, 53-57.
42. Chopra, A. K. & Houston, C. W. 1989 Purification and partial characterization of a cytotonic enterotoxin produced by Aeromonas hydrophila. Can. J. Microbiol. 35, 719-727.
43. Chopra, A. K. & Houston, C. W. 1999 Enterotoxins in Aeromonas-associated gastroenteritis. Microbes Infect. 1, 1129-1137.
44. Chopra, A. K., Houston, C. W., Genaux, C. T., Dixon, J. D. & Kurosky, A. 1986 Evidence for production of an enterotoxin and cholera toxin cross-reactive factor by Aeromonas hydrophila. J. Clin. Microbiol. 24, 661-664.
45. Chopra, A. K., Vo, T. N. & Houston, C. W. 1992 Mechanism of action of a cytotonic enterotoxin produced by Aeromonas hydrophila. FEMS Microbiol. Lett. 91, 15-19.
46. Chopra, A. K., Houston, C. W., Peterson, J. W. & Jin, G. F. 1993 Cloning, expression, and sequence analysis of a cytolytic enterotoxin gene from Aeromonas hydrophila. Can. J. Microbiol. 39, 513-523.
47. Chopra, A. K., Pham, R. & Houston, C. W. 1994 Cloning and expression of putative cytotonic enterotoxin-coding genes from Aeromonas hydrophila. Gene 139, 87-91.
48. Chopra, A. K., Peterson, J. W., Xu, X. -J., Coppenhaver, D. H. & Houston, C. W. 1996 Molecular and biochemical characterization of a heat-labile enterotoxin from Aeromonas hydrophila. Microb. Pathog. 21, 357-377.
49. Chopra, A. K., Xu, X. -J., Ribardo, D., Kuhl, K., Gonzalez, M., Peterson, J. W. & Houston, C. W. 2000 The cytotoxic enterotoxin of Aeromonas hydrophila induces proinflammatory cytokine production and activates arachidonic acid metabolism in macrophages. Infect. Immun. 68, 2808-2818.
50. Christman, J. W., Blackwell, T. S. & Juurlink, B. H. 2000 Redox regulation of nuclear factor kappa B: therapeutic potential for attenuating inflammatory responses. Brain Pathol. 10, 153-162.
51. Crivelli, C., Demarta, A. & Peduzzi, R. 2001 Intestinal secretory immunoglobulin A (sIgA) response to Aeromonas exoproteins in patients with naturally acquired Aeromonas diarrhea. FEMS Immun. Med. Microbiol. 30, 31-35.
52. Dacanay, A., Johnson, S. C., Bjornsdottir, R., Ebanks, R. O., Ross, N. W., Reith, M., Singh, R. K., Hiu, J. & Brown, L. L. 2003 Molecular characterization and quantitative analysis of superoxide dismutases in virulent and avirulent strains of Aeromonas salmonicida subsp. salmonicida. J. Bacteriol. 185, 4336-4344.
53. Davis, W. A., Kane, J. G. & Garagusi, V. F. 1978 Human Aeromonas infections: a review of the literature and a case report of endocarditis. Medicine 57, 267-277.
54. Deodhar, L. P., Saraswathi, K. & Varudkar, A. 1991 Aeromonas spp. and their association with human diarrheal disease. J. Clin. Microbiol. 29, 853-856.
55. Deutsch, S. F. & Wedzina, W. 1997 Aeromonas sobria-associated left-sided segmental colitis [review]. Am. J. Gastroenterol. 92, 2104-2106.
56. Dixon, B. 1987 Commentary: an apostrophe to Aeromonads. Biotechnology 5.
57. Ebanks, R. O., Dacanay, A., Goguen, M., Pinto, D. M. & Ross, N. W. 2004 Differential proteomic analysis of Aeromonas salmonicida outer membrane proteins in response to low iron and in vivo growth conditions. Proteomics 4, 1074-1085.
58. Eko, F. O. & Utsalo, S. J. 1989 Characterization and significance of Aeromonas spp. isolated from diarrhoeic stools in Nigeria. J. Trop. Med. Hyg. 92, 97-101.
59. Epple, H. J., Mankertz, J., Ignatius, R., Liesenfeld, O., Fromm, M., Zeitz, M., Chakraborty, T. & Schulzke, J. D. 2004 Aeromonas hydrophila beta-hemolysin induces active chloride secretion in colon epithelial cells (HT-29/B6). Infect. Immun. 72, 4848-4858.
60. Erova, T. E., Fadl, A. A., Sha, J., Khajanchi, B. K., Pillai, L. L., Kozlova, E. V. & Chopra, A. K. 2006 Mutations within the catalytic motif of DNA adenine methyltransferase (Dam) of Aeromonas hydrophila reverts the virulence of the Dam-overproducing strain to that of the wild-type phenotype. Infect. Immun. 74, 5763-5772.
61. Erova, T. E., Pillai, L., Fadl, A. A., Sha, J., Wang, S., Galindo, C. L. & Chopra, A. K. 2006 DNA adenine methyltransferase influences virulence of Aeromonas hydrophila. Infect. Immun. 74, 410-424.
62. Erova, T. E., Sha, J., Horneman, A. J, Borchardt, M. A., Khajanchi, B. K., Fadl, A. A. & Chopra, A. K. 2007 Identification of a new hemolysin from diarrheal isolate SSU of Aeromonas hydrophila. FEMS Microbiol. Lett. 275, 301-311.
63. Erova, T. E., Kosykh, V. G., Fadl, A. A., Sha, J., Horneman, A. J. & Chopra, A. K. 2008 Cold shock exoribonuclease R (VacB) is involved in Aeromonas hydrophila pathogenesis. J. Bacteriol. 190, 3467-3474.
64. Escolar, L., Perez-Martin, J. & de Lorenzo, V. 1998 Binding of the Fur (ferric uptake regulator) repressor of Escherichia coli to arrays of the GATAAT sequence. J. Mol. Biol. 283, 537-547.
65. Esteve, C., Alcaide, E., Canals, R., Merino, S., Blasco, D., Figueras, M. J. & Tomas, J. M. 2004 Pathogenic Aeromonas hydrophila serogroup O:14 and O:81 strains with an S-layer. Appl. Environ. Microbiol. 70, 5898-5904.
66. Fadl, A. A., Galindo, C. L., Sha, J., Erova, T. E., Houston, C. W., Olano, J. P. & Chopra, A. K. 2006 Deletion of the genes encoding the type III secretion system and cytotoxic enterotoxin alters host responses to Aeromonas hydrophila infection. Microb. Pathog. 40, 198-210.
67. Fadl, A. A., Galindo, C. L., Sha, J., Zhang, F., Garner, H. R., Wang, H. -Q. & Chopra, A. K. 2007 Global transcriptional responses of wild-type Aeromonas hydrophila and its virulence-deficient mutant in a murine model of infection. Microb. Pathog. 42, 193-203.
68. Falcon, R. M., Carvalho, H. F., Joazeiro, P. P., Gatti, M. S. V. & Yano, T. 2001 Induction of apoptosis in HT29 human intestinal epithelial cells by the cytotoxic enterotoxin of Aeromonas hydrophila. Biochem. Cell Biol. 79, 525-531.
69. Ferguson, M. R., Xu, X. -J., Houston, C. W., Peterson, J. W. & Chopra, A. K. 1995 Amino-acid residues involved in biological functions of the cytolytic enterotoxin from Aeromonas hydrophila. Gene 156, 79-83.
70. Ferguson, M. R., Xu, X. -J., Houston, C. W., Peterson, J. W., Coppenhaver, D. H., Popov, V. L. & Chopra, A. K. 1997 Hyperproduction, purification, and mechanism of action of the cytotoxic enterotoxin produced by Aeromonas hydrophila. Infect. Immun. 65, 4299-4308.
71. Figueras, M. J. 2005 Clinical relevance of Aeromonas sM503. Rev. Med. Microbiol. 16, 145-153. Filler, G., Ehrich, J. H. H. & Beutim, E. S. L. 2000 Acute renal failure in an infant associated with cytotoxic Aeromonas sobria isolated from patient's stool and from aquarium water as suspected source of infecton. J. Clin. Microbiol. 38, 469-470.
72. Fivaz, M., Abrami, L., Tsitrin, Y. & Gisou van der Goot, F. 2001 Not as simple as just punching a hole. Toxicon 39, 1637-1645.
73. Freij, B. J. 1984 Aeromonas: biology of the organism and diseases in children. Pediat. Infect. Dis. 3, 164-175.
74. Fujii, Y., Nomura, T., Yokoyama, R., Shinoda, S. & Okamoto, K. 2003 Studies of the mechanism of action of the aerolysin-like hemolysin of Aeromonas sobria in stimulating T84 cells to produce cyclic AMP. Infect. Immun. 71, 1557-1560.
75. Fulghum, D. D., Linton, W. R. Jr. & Taplin, D. 1978 Fatal Aeromonas hydrophila infection of the skin. Southern Med. J. 71, 739-741.
76. Funada, H. & Matsuda, T. 1997 Aeromonas bacteremia in patients with hematologic diseases. Int. Med. 36, 171-174.
77. Galindo, C. L., Sha, J., Ribardo, D. A., Fadl, A. A., Pillai, L. & Chopra, A. K. 2003 Identification of Aeromonas hydrophila cytotoxic enterotoxin-induced genes in macrophages using microarrays. J. Biol. Chem. 278, 40198-40212.
78. Galindo, C. L., Fadl, A. A., Sha, J. & Chopra, A. K. 2004 Microarray analysis of Aeromonas hydrophila cytotoxic enterotoxintreated murine primary macrophages. Infect. Immun. 72, 5439-5445.
79. Galindo, C. L., Fadl, A. A., Sha, J., Gutierrez, C., Jr., Popov, V. L., Boldogh, I., Aggarwal, B. B. & Chopra, A. K. 2004 Aeromonas hydrophila cytotoxic enterotoxin activates mitogen-activated protein kinases and induces apoptosis in murine macrophages and human intestinal epithelial cells. J. Biol. Chem. 279, 37597-37612.
80. Galindo, C. L., Fadl, A. A., Sha, J., Pillai, L., Gutierrez, C., Jr. & Chopra, A. K. 2005 Microarray and proteomics analyses of human intestinal epithelial cells treated with the Aeromonas hydrophila cytotoxic enterotoxin. Infect. Immun. 73, 2628-2643.
81. Galindo, C. L., Gutierrez, C., Jr. & Chopra, A. K. 2006 Potential involvement of galactin-3 and SNAP23 in Aeromonas hydrophila cytotoxic enterotoxin-induced host cell apoptosis. Microb. Pathog. 40, 56-68.
82. Gavin, R., Rabaan, A. A., Marino, S., Tomas, J. M., Gryllos, I. & Shaw, J. G. 2002 Lateral flagella of Aeromonas species are essential for epithelial cell adherence and biofilm formation. Mol. Microbiol. 43, 383-397.
83. Gilardi, G. L., Bottone, E. & Birnbaum, M. 1970 Unusual fermentative, gram-negative bacilli isolated from clinical specimens. II. Characterization of Aeromonas species. Appl. Microbiol. 20, 156-159.
84. Gracey, M. 1988 Gastroenteritis in Australian children. Studies on the etiology of acute diarrhea. Ann. Trop. Pediatr. 8, 68-75.
85. Gracey, M., Robinson, J. & Burke, V. 1982 Aeromonas-associated gastroenteritis. Lancet 11, 1304-1306.
86. von Graevenitz, A. 1987 Research on Aeromonas and Plesiomonas. Experientia 43, 348-349.
87. Graf, J. 1999 Symbiosis of Aeromonas veronii biovar sobria and Hirudo medicinalis, the medicinal leech: a novel model for digestive tract associations. Infect. Immun. 67, 1-7.
88. Granum, P. E., O'Sullivan, K., Tomás, J. M. & Ørmen, Ø. 1998 Possible virulence factors of Aeromonas spp. from food and water. FEMS Immun. Med. Microbiol. 21, 131-137.
89. Grey, P. A. & Kirov, S. M. 1993 Adherence to HEp-2 cells and enteropathogenic potential of Aeromonas spp. Epidemiol. Infect. 110, 279-287.
90. Gromez, C. J., Munoz, P., Prieto, F. L., Fernandez, R. R., Robles, M., Creixems, M. R. & Santiago, E. B. 1996 Gastroenteritis due to Aeromonas in pediatrics (in Spanish). Anal. Espan. Pediatr. 44, 548-552.
91. Guimaraes, M. S., Andrade, J. R. C., Freitas-Almeida, A. C. & Ferreira, M. C. S. 2002 Aeromonas hydrophila vaculating activity in the Caco-2 human enterocyte cell line as a putative virulence factor. FEMS Microbiol. Lett. 207, 127-131.
92. Gyles, C. L. 1992 Escherichia coli cytotoxins and enterotoxins. Can. J. Microbiol. 38, 734-746.
93. Hanninen, M. L., Salmi, S., Mattila, L., Taipalinen, R. & Siitonen, A. 1995 Association of Aeromonas spp. with travellers' diarrhoea in Finland. J. Med. Microbiol. 42, 26-31.
94. Hanninen, M. L., Oivanen, P. & Hirvela-Koski, V. 1997 Aeromonas species in fish, fish-eggs, shrimp and freshwater. Int. J. Food Microbiol. 34, 17-26.
95. Harf-Monteil, C., Fleche, A. L., Riegel, P., Prevost, G., Bermond, D., Grimont, P. A. D. & Monteil, H. 2004 Aeromonas simiae sp. nov. isolated from monkey faeces. Int. J. Syst. Evol. Microbiol. 54, 481-485.
96. Hichman-Brenner, F. W., Fanning, G. R., Arduino, M. J., Brenner, D. J. & Farmer, J. J., III 1988 Aeromonas schubertii, a new mannitol-negative species found in human clinical specimens. J. Clin. Microbiol. 26, 1561-1564.
97. Hofer, E., Reis, C. M., Theophilo, G. N., Cavalcanti, V. O., Lima, N. V. & Henriques, M. deF. 2006 Aeromonas associated with an acute diarrhea outbreak in Sao Bento de Una, Pernambuco. Rev. Soc. Bras. Med. Trop. 39, 217-220.
98. Holmberg, S. D. 1988 Vibrios and Aeromonas. Infect. Diarrhea 2, 656-676.
99. Holmes, P., Niccolls, L. M. & Sartory, D. P. 1996 The ecology of mesophilic Aeromonas. In The Genus Aeromonas (ed. B. Austin, M. Altwegg, P. J. Golling & S. W. Joseph), pp. 127-150. John Wiley & Sons, Chichester.
100. Holston, K. V. I., Zandvliet, S. E., Rodriguez, S., Nguyen, H. T. & Bodey, G. P. 1991 Spectrum of Aeromonas and Plesiomonas infections in patients with cancer and AIDS. Experientia 47, 437-439.
101. Hossain, M. A., Rahman, K. M., Asna, S. M., Rahim, Z., Hussain, T. & Miah, M. R. 1992 Incidence of Aeromonas isolated from diarrhoeal children and study of some virulence factors in the isolates, Bangladesh. Med. Res. Council Bull. 18, 61-67.
102. Howard, S. P. & Buckley, J. T. 1986 Molecular cloning and expression in Escherichia coli of the structural gene for the hemolytic toxin aerolysin from Aeromonas hydrophila. Mol. Gen. Genet. 204, 289-295.
103. Howard, S. P., Meiklejohn, H. G., Shivak, D. & Jahagirdar, R. 1996 A TonB-like protein and a novel membrane protein containing an ATP-binding cassettee function together in exotoxin secretion. Mol. Microbiol. 22, 595-604.
104. Hunter, P. R. & Burke, S. H. 1987 Isolation of Aeromonas caviae from ice-cream. Lett. Appl. Microbiol. 4, 45.
105. Indergand, S. & Graf, J. 2000 Ingested blood contributes to the specificity of the symbiosis of Aeromonas veronii biovar sobria and Hirudo medicinalis, the medicinal leech. Appl. Environ. Microbiol. 66, 4735-4741.
106. Itoh, H., Kuwata, G., Tateyama, S., Yamashita, K., Inoue, T., Kataoka, H., Ido, A., Ogata, K., Takasaki, M., Inoue, S., Tsubouchi, H. & Koono, M. 1999 Aeromonas sobria infection with severe soft tissue damage and segmental necrotizing gastroenteritis in a patient with alcoholic liver cirrhosis. Pathol. Inter. 49, 541-546.
107. Ivanova, E. P., Zhukova, N. V., Gorshkova, N. M. & Chaikina, E. L. 2001 Characterization of Aeromonas and Vibrio species isolated from a drinking water reservoir. J. Appl. Microbiol. 90, 919-927.
108. Janda, J. M. & Abbott, S. L. 1998 Evolving concepts regarding the genus Aeromonas: an expanding panorama of species, disease presentations, and unanswered questions. Clin. Infect. Dis. 27, 332-344.
109. Janda, J. M. & Brenden, R. 1987 Importance of Aeromonas sobria in Aeromonas bacteremia. J. Infect. Dis. 155, 589-591.
110. Janda, J. M. & Duffey, P. S. 1988 Mesophilic aeromonads in human disease: current taxonomy, laboratory identification, and infectious disease spectrum. Rev. Infect. Dis. 10, 980-997.
111. Jimenez, N., Canals, R., Lacaster, A., Kondakova, A. N., Lindner, B., Knirel, Y. A., Merino, S., Regue, M. & Tomas, J. M. 2008 Molecular analysis of three Aeromonas hydrophila AH-3 (serotype O34) lipopolysaccharide core biosynthesis gene clusters. J. Bacteriol. 190, 3176-3184.
112. Jin, G. -F. & Houston, C. W. 1992 Effect of Aeromonas hydrophila enterotoxins on function of mouse phagocytes. Digest. Dis. Sci. 11, 1697-1703.
113. Jin, G. F., Chopra, A. K. & Houston, C. W. 1992 Stimulation of neutrophil leukocyte chemotaxis by a cloned cytolytic enterotoxin of Aeromonas hydrophila. FEMS Microbiol. Lett. 77, 285-290.
114. Joseph, S. W., Daily, O. P., Hunt, W. S., Seidler, R. J., Allen, D. A. & Colwell, R. R. 1979 Aeromonas primary wound infection of a diver in polluted waters. J. Clin. Microbiol. 10, 46-49.
115. Kay, W. W. & Trust, T. J. 1991 Form and functions of the regular surface array (S-layer) of Aeromonas salmonicida. Experientia 47, 412-414.
116. Keusch, G. T. & Donta, S. T. 1975 Classification of enterotoxins on the basis of activity in cell culture. J. Infect. Dis. 131, 58-63.
117. Khanolkar-Gaitondo, S. S., Reubish, G. K., Lee, C. K. & Stadtlander, C. T. K. H. 2000 Isolation of bacteria other than Helicobacter pylori from stomachs of squirrel monkeys (Saimiri spp.) with gastritis. Digest. Dis. Sci. 45, 272-280.
118. Kirov, S. M., Ardestani, E. K. & Hayward, L. J. 1993 The growth and expression of virulence factors at refrigeration temperature by Aeromonas strains isolated from foods. Int. J. Food Microbiol. 20, 159-168.
119. Kirov, S. M., O'Donovan, L. A. & Sanderson, K. 1999 Functional characterization of type IV pili expressed on diarrheaassociated isolates of Aeromonas species. Infect. Immun. 67, 5447-5454.
120. Kirov, S. M., Barnett, T. C., Pepe, C. M., Strom, M. S. & Albert, M. J. 2000 Investigation of the role of type IV Aeromonas pilus (Tap) in the pathogenesis of Aeromonas gastrointestinal infection. Infect. Immun. 68, 4040-4048.
121. Kirov, S. M., Tassell, B. C., Semmler, A. B. T., O'Donovan, L. A., Rabaan, A. A. & Shaw, J. G. 2002 Lateral flagella and swarming motility in Aeromonas species. J. Bacteriol. 184, 547-555.
122. Kirov, S. M., Castrisios, M. & Shaw, J. G. 2004 Aeromonas flagella (polar and lateral) are entrocyte adhesions that contribute to biofilm formation on surfaces. Infect. Immun. 72, 1939-1945.
123. Ko, W. C., Lee, H. C., Chuang, Y. C., Liu, C. C. & Wu, J. J. 2000 Clinical features and therapeutic implications of 104 episodes of monomicrobial Aeromonas bacteraemia. J. Infect. 40, 267-273.
124. Kohashi, T., Sakai, H., Marumo, F. & Sato, C. 1995 Aeromonas sobria infection with severe muscle degeneration in a patient with alcoholic liver cirrhosis. Am. J. Gastroenterol. 90, 2234-2235.
125. 2+ release from intracellular stores in human granulocytes. J. Biol. Chem. 273, 18122-18129.
126. Krovacek, K., Pasquale, V., Baloda, S. B., Soprano, V., Conte, M. & Dumontet, S. 1994 Comparison of putative virulence factors in Aeromonas hydrophila strains isolated from the marine environment and human diarrheal cases in Southern Italy. Appl. Environ. Microbiol. 60, 1372-1382.
127. Kuhn, I., Albert, M. J., Ansaruzzaman, M., Bhuiyan, N. A., Alabi, S. A., Islam, M. S., Neogi, P. K., Huys, G., Janssen, P., Kersters, K. & Mollby, R. 1997 Characterization of Aeromonas spp. isolated from humans with diarrhea, from healthy controls, and from surface water in Bangladesh. J. Clin. Microbiol. 35, 369-373.
128. Lawson, M. A., Burke, V. & Chang, B. J. 1985 Invasion of HEp-2 cells by fecal isolates of Aeromonas hydrophila. Infect. Immun. 47, 680-683.
129. Leclere, V., Bechet, M. & Blondeau, R. 2004 Functional significance of a periplasmic Mn-superoxide dismutase from Aeromonas hydrophila. J. Appl. Microbiol. 96, 828-833.
130. Leung, K. Y. & Stevenson, R. M. W. 1988 Characteristics and distribution of extracellular proteases from Aeromonas hydrophila. J. Gen. Microbiol. 134, 151-160.
131. Lin, S. H., Shieh, S. D., Lin, Y. F., Debrauwer, E., vanLanduyt, H. W., Gordts, B. & Boelaert, J. R. 1996 Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine. Am. J. Kidney Dis. 27, 733-735.
132. Ljungh, A., Eneroth, P. & Wadstrom, T. 1982a Steroid secretion in adrenal Y1 cells exposed to Aeromonas hydrophila enterotoxin. FEMS Microbiol. Lett. 15, 141-144.
133. Ljungh, A., Eneroth, P. & Wadstrom, T. 1982b Cytotonic enterotoxin from Aeromonas hydrophila. Toxicon 20, 787-794.
134. Ljungh, A. & Kronevi, T. 1982 Aeromonas hydrophila toxins-intestinal fluid accumulation and mucosal injury in animal models. Toxicon 20, 397-407.
135. Ljungh, A. &Wadstrom, T. 1986 Aeromonas toxins. In Pharmacology of Bacterial Toxins (ed. F. Dorner & J. Drews), pp. 289-301. Pergamon, New York, NY.
136. Lye, D. J., Rogers, M. R., Stelma, G., Vesper, S. J. & Hayes, S. L. 2007 Characterization of Aeromonas virulence using an immunocompromised mouse model. Curr. Microbiol. 54, 195-198.
137. Lynch, M. J., Swift, S., Kirke, D. F., Keevil, C. W., Dodd, C. E. R. & Williams, P. 2002 The regulation of biofilm development by quorum sensing in Aeromonas hydrophila. Environ. Microbiol. 4, 18-28.
138. Majeed, K. N., Egan, A. F. & MacRae, I. C. 1990 Production of exotoxins of Aeromonas spp. at 5°C. J. Appl. Bacteriol. 69, 332-337.
139. Mani, S., Sadigh, M. & Adriole, V. T. 1995 Clinical spectrum of Aeromonas hydrophila infections: report of 11 cases in a community hospital and review. Infect. Dis. Clin. Pract. 4, 9-86.
140. Martinez-Silva, V. R., Guzman-Urrego, M. & Caselitz, F. H. 1961 On the problem of the significance of Aeromonas strain in enteritis in infants. Z. Tropenmend. Parasitol. 12, 445-451.
141. Martino, R., Santamaria, A., Pericas, R., Sureda, A. & Brunet, S. 1997 Acute rhabdomyolysis and myonecrosis complicating Aeromonas bacteremia in neutropenic patients with hematologic malignancies: report of two cases. Haematologica 82, 692-694.
142. Martino, R., Gomez, L., Pericas, R., Salazar, R., Sola, C., Sierra, J. & Garau, J. 2000 Bacteraemia caused by non-glucosefermenting gram-negative bacilli and Aeromonas species in patients with haematological malignancies and solid tumours. Eur. J. Clin. Microbiol. Infect. Dis. 19, 320-323.
143. Masada, C. L., LaPatra, S. E., Morton, A. W. & Strom, M. S. 2002 An Aeromonas salmonicida type IV pilin is required for virulence in rainbow trout Oncorhynchus mykiss. Dis. Aquat. Organ. 15, 13-25.
144. McCardell, B. A., Madden, J. M., Kothary, M. H. & Sathyamoorthy, V. 1995 Purification and characterization of CHO cellelongating toxin produced by Aeromonas hydrophila. Microb. Pathog. 19, 1-9.
145. Merino, S., Rubires, X., Knochel, S. & Tomas, J. M. 1995 Emerging pathogens: Aeromonas spp. Int. J. Food Microbiol. 28, 157-168.
146. Merino, S., Rubires, X., Aguilar, A., Alberti, S., Hernandez-Alles, S., Benedi, V. J. & Tomas, J. M. 1996 Mesophilic Aeromonas sp. Serogroup 0:11 resistance to complement-mediated killing. Infect. Immun. 64, 5302-5309.
147. Merino, S., Rubires, X., Aguillar, A., Guillot, J. F. & Tomas, J. M. 1996 The role of the O-antigen lipopolysaccharide on the colonization in vivo of the germfree chicken gut by Aeromonas hydrophila serogroup 0:34. Microb. Pathog. 20, 325-333.
148. Merino, S., Nogueras, M. M., Aguilar, A., Rubires, X., Alberti, S., Benedi, V. J. & Tomas, J. M. 1998 Activation of the complement classical pathway (C1q binding) by mesophilic Aeromonas hydrophila outer membrane protein. Infect. Immun. 66, 3825-3831.
149. Merino, S., Altarriba, M., Gavin, R., Izquierdo, L. & Tomas, J. M. 2001 The cell division genes ( ftsE and X) of Aeromonas hydrophila and their relationship with opsonopahagocytosis. FEMS Microbiol. Lett. 198, 183-188.
150. 2+ transport protein is involved in Aeromonas hydrophila adherence. FEMS Microbiol. Lett. 198, 189-195.
151. Minnaganti, V. R., Patel, P. J., Iancu, D., Schoch, P. E. & Cunha, B. A. 2000 Necrotizing fasciitis caused by Aeromonas hydrophila. Case Stud. Infect. Dis. 29, 306-308.
152. Morgan, D. R., Johnson, P. C., DuPont, H. L., Satterwhite, T. K. & Wood, L. V. 1985 Lack of correlation between known virulence properties of Aeromonas hydrophila and enteropathogenicity for humans. Infect. Immun. 50, 62-65.
153. Murakami, T., Inoue, T., Kawakami, H., Takahashi, H. & Yasunaga, T. 1995 Hypercalcemia associated with Aeromonas hydrophila gastroenteritis. Acta Paediatr. Jpn 37, 192-195.
154. Murata, H., Yoshimoto, H., Masuo, M., Tokuda, H., Kitamura, S., Otsuka, Y. & Miura, Y. 2001 Fulminant pneumonia due to Aeromonas hydrophila in a man with chronic renal failure and liver cirrhosis. Int. Med. 40, 118-123.
155. Nakasone, N., Toma, C., Song, T. & Iwanaga, M. 2004 Purification and characterization of a novel metalloprotease isolated from Aeromonas caviae. FEMS Microbiol. Lett. 237, 127-132.
156. Namdari, H. & Bottone, E. J. 1990 Microbiological and clinical evidence supporting the role of Aeromonas caviae as a pediatric enteric pathogen. J. Clin. Microbiol. 28, 837-840.
157. Nogueras, M. M., Merino, S., Aguilar, A., Benedi, V. J. & Tomas, J. M. 2000 Cloning, sequencing, and role in serum susceptibility of porin II from mesophilic Aeromonas hydrophila. Infect. Immun. 68, 1849-1854.
158. Nojimoto, I. T., Bezana, C., do Carmo, C., Valadao, L. M. & Carrijo, K. D. M. 1997 The prevelance of Aeromonas spp. in the diarrheal feces of children under the age of 5 years in the city of Goiania Goias in the 1995-1996 biennium (in Portuguese). Rev. Sociedade Brasil Med. Trop. 30, 385-388.
159. Ormen, O. & Ostensvik, O. 2001 The occurrence of aerolysinpositive Aeromonas spp. and their cytotoxicity in Norwegian water sources. J. Appl. Microbiol. 90, 797-802.
160. Ouderkirk, J. P., Bekhor, D., Turett, G. S. & Murali, R. 2004 Aeromonas meningitis complicating medicinal leech therapy. Clin. Infect. Dis. 38, e36-e37.
161. Palumbo, S. A., Maxino, F., Williams, A. C., Buchanan, R. L. & Thayer, D. W. 1985 Starch-ampicillin agar for the quantitative detection of Aeromonas hydrophila. Appl. Environ. Microbiol. 50, 1027-1030.
162. Palumbo, S. A., Bencivengo, M. M., Corral, F. D., Wiilliams, A. C. & Buchanan, R. L. 1989 Characterization of the Aeromonas hydrophila group isolated from retail foods of animal origin. J. Clin. Microbiol. 27, 854-859.
163. Pavlov, D., de Wet, C. M. E., Grabow, W. O. K. & Ehlers, M. M. 2004 Potentially pathogenic features of heterotrophic plate count bacteria isolated from treated and untreated drinking water. Int. J. Food. Microbiol. 92, 275-287.
164. Pemberton, J. M., Kidd, S. P. & Schmidt, R. 1997 Secreted enzymes of Aeromonas. FEMS Microbiol. Lett. 152, 1-10.
165. Pepe, C. M., Eklund, M. W. & Strom, M. S. 1996 Cloning of an Aeromonas hydrophila type IV pilus biogenesis gene cluster: complementation of pilus assembly functions and characterization of a type IV leader peptidase/ N-methyltransferase required for extracellular protein secretion. Mol. Microbiol. 194, 857-869.
166. Pidiyar, V., Jangid, K., Patole, M. S. & Shouche, Y. S. 2004 Studies on cultured and uncultured microbiota of wild Culex quinquefasciatus mosquito midgut based on 16S ribosomal RNA gene analysis. Am. J. Trop. Med. Hyg. 70, 597-603.
167. Pillai, L., Sha, J., Erova, T. E., Fadl, A. A. & Chopra, A. K. 2006 Molecular and functional characterization of a ToxR-regulated lipoprotein from a clinical isolate of Aeromonas hydrophila. Infect. Immun. 74, 3742-3755.
168. Potomski, J., Burk, V., Robinson, J., Fumarola, D. & Miragliotta, G. 1987 Aeromonas cytotonic enterotoxin cross-reactive with cholera toxin. J. Med. Microbiol. 23, 179-186. Quinn, J. P. 1991 IHL enteric bacterial disease surveillance. Lab. Hotline 28, 2.
169. Rabaan, A. A., Gryllos, I., Tomas, J. M. & Shaw, J. G. 2001 Motility and the polar flagellum are required for Aeromonas caviae adherence to HEp-2 cells. Infect. Immun. 69, 4257-4267.
170. Rahim, Z., Khan, S. I. & Chopra, A. K. 2004 Biological characterization of Aeromonas spp. isolated from the environment. Epidemiol. Infect. 132, 627-636.
171. Ribardo, D. A., Crowe, S. E., Kuhl, K. R., Peterson, J. W. & Chopra, A. K. 2001 Prostaglandin levels in stimulated macrophages are controlled by phospholipase A2-activating protein and by activation of phospholipase C and D. J. Biol. Chem. 276, 5467-5475.
172. Ribardo, D. A., Kuhl, K. R., Boldogh, I., Peterson, J. W., Houston, C. W. & Chopra, A. K. 2002 Early cell signaling by the cytotoxic enterotoxin of Aeromonas hydrophila in macrophages. Microb. Pathog. 32, 149-163.
173. Ribas, F., Perramon, J., Terradillos, A., Frias, F. & Lucena, F. 2000 The Pseudomonas group as an indicator of potential regrowth in water distribution systems. J. Appl. Microbiol. 88, 704-710.
174. Rigney, M. M., Zilinsky, J. W. & Rouf, M. A. 1978 Pathogenicity of Aeromonas hydrophila in red leg disease in frogs. Curr. Microbiol. 1, 175-179.
175. Riley, P. A., Parasakthi, N. & Liam, C. K. 1996 Development of Aeromonas hydrophila bacteremia in a patient recovering from cholera. Clin. Infect. Dis. 22, 867-868.
176. Rose, J. M., Houston, C. W., Coppenhaver, D. H., Dixon, J. D. & Kurosky, A. 1989a Purification and chemical characterization of a cholera toxin-cross-reactive cytolytic enterotoxin produced by a human isolate of Aeromonas hydrophila. Infect. Immun. 57, 1165-1169.
177. Rose, J. M., Houston, C. W. & Kurosky, A. 1989b Bioactivity and immunological characterization of a cholera toxin-cross-reactive cytolytic enterotoxin from Aeromonas hydrophila. Infect. Immun. 57, 1170-1176.
178. do Sola Earle, C., Montiel Quezel-Guerraz, N., Hidalgo Rojas, L., Sanchez Cantos, A. & Garcia Alegria, J. 1997 Severe acute gastroenteritis due to Aeromonas in a patient colectomized for Crohns' disease (in Spanish). Rev. Espanola Enfermedades Digestivas 89, 48-50.
179. Sanderson, K., Ghazali, F. M. & Kirov, S. M. 1996 Colonization of streptomycin-treated mice by Aeromonas species. J. Diarrhoeal Dis. Res. 14, 27-32.
180. Sanyal, S. C., Singh, S. J. & Sen, B. C. 1975 Enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides. J. Med. Microbiol. 8, 195-199.
181. Schoch, P. E. & Cunha, B. A. 1984 Aeromonas. Infect. Control 5, 542-544.
182. Scholz, D., Scharmann, W. & Blobel, H. 1974 Leucocidic substances from Aeromonas hydrophila. Zbl. Bakt. Hyg. I. Abt. Orig. A. 228, 312-316.
183. Schulz, A. J. & McCardell, B. A. 1988 DNA homology and immunological cross-reactivity between Aeromonas hydrophila cytotonic toxin and cholera toxin. J. Clin. Microbiol. 26, 57-61.
184. Sen, K. & Lye, D. 2007 Importance of flagella and enterotoxins for Aeromonas virulence in a mouse model. Can. J. Microbiol. 53, 261-269.
185. Sen, K. & Rogers, M. 2004 Distribution of six virulence factors in Aeromonas species isolated from US drinking water utilities: a PCR identification. J. Appl. Microbiol. 97, 1077-1086.
186. Seshadri, R., Joseph, S. W., Chopra, A. K., Sha, J., Shaw, J., Graf, J., Haft, D., Wu, M., Ren, Q., Rosovitz, M. J., Madupu, R., Tallon, L., Kim, M., Jin, S., Vuong, H., Stine, C., Ali, A., Horneman, A. J. & Heidelberg, J. F. 2006 Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades. J. Bacteriol. 188, 8272-8282.
187. Sha, J., Lu, M. & Chopra, A. K. 2001 Regulation of the cytotoxic enterotoxin gene in Aeromonas hydrophila: characterization of an iron uptake regulator. Infect. Immun. 69, 6370-6381.
188. Sha, J., Kozlova, E. & Chopra, A. K. 2002 Role of various enterotoxins in Aeromonas hydrophila induced gastroenteritis: generation of enterotoxin gene deficient mutants and evaluation of their enterotoxic activity. Infect. Immun. 70, 1924-1935.
189. Sha, J., Galindo, C. L., Pancholi, V., Popov, V. L. & Chopra, A. K. 2003 Differential expression of the enolase gene under in vivo versus in vitro growth conditions of Aeromonas hydrophila. Microb. Pathog. 34, 194-204.
190. Sha, J., Kozlova, E. V., Fadl, A. A., Houston, C. W., Peterson, J. W. & Chopra, A. K. 2004 Molecular characterization of a glucose-inhibited division gene (gidA) that regulates cytotoxic enterotoxin of Aeromonas hydrophila. Infect. Immun. 78, 1084-1095.
191. Sha, J., Pillai, L., Fadl, A. A., Erova, T. E., Galindo, C. L. & Chopra, A. K. 2005 The type III secretion system and cytotoxic enterotoxin alter the virulence of Aeromonas hydrophila. Infect. Immun. 73, 6446-6457.
192. Sha, J., Wang, S. F., Suarez, G., Sierra, J. C., Fadl, A. A., Erova, T. E., Foltz, S. M., Khajanchi, B. K., Silver, A. C., Graf, J., Schein, C. H. & Chopra, A. K. 2007 Further characterization of a type III secretion system (T3SS) and of a new effector protein from a clinical isolate of Aeromonas hydrophila-Part I. Microb. Pathog. 43, 127-146.
193. Sierra, J. C., Suarez, G., Sha, J., Foltz, S. M., Popov, V. L., Galindo, C. L., Garner, H. R. & Chopra, A. K. 2007 Biological characterization of a new type III secretion system effector from a clinical isolate of Aeromonas hydrophila-Part II. Microb. Pathog. 43, 147-160.
194. Silver, A. C., Kikuchi, Y., Fadl, A. A., Sha, J., Chopra, A. K. & Graf, J. 2007 Interaction between innate immune cells and a bacterial type-three secretion system in mutualistic and pathogenic associations. Proc. Natl Acad. Sci. USA 104, 9481-9486.
195. Singh, D. V. & Sanyal, S. C. 1992 Enterotoxicity of clinical and environmental isolates of Aeromonas spp. J. Med. Microbiol. 36, 269-272.
196. Snower, D. P., Ruef, C., Kuritza, A. P. & Edberg, S. C. 1989 Aeromonas hydrophila infection associated with the use of medicinal leeches. J. Clin. Microbiol. 27, 1421-1422.
197. Song, T., Toma, C., Nakasone, N. & Iwanaga, M. 2004 Aerolysin is activated by metalloprotease in Aeromonas veronii biovar sobria. J. Med. Microbiol. 53, 477-482.
198. Spangler, B. D. 1992 Structure and function of cholera toxin and related Escherichia coli heat-labile enterotoxin. Microbiol. Rev. 56, 622-647.
199. Stojiljkovic, I., Baumler, A. J. & Hantke, K. 1994 Identification and characterization of new iron regulated Escherichia coli gene by Fur titration assay. J. Mol. Biol. 236, 531-545.
200. Suarez, G., Sierra, J. C., Sha, J., Wang, S., Erova, T. E., Fadl, A. A., Foltz, S. M., Horneman, A. J. & Chopra, A. K. 2008 Molecular characterization of a functional type VI secretion system from a clinical isolate of Aeromonas hydrophila. Microb. Pathog. 44, 344-361.
201. Suthienkul, O., Aiumlaor, P., Siripanichgon, K., Eampokalap, B., Kikhanonsakul, S., Utrarachkij, F. & Rakue, Y. 2001 Bacterial causes of AIDS-associated diarrhea in Thailand. SE Asian J. Tropical Med. Pub. Health 32, 158-170.
202. Swift, S., Karlyshev, A. V., Fish, L., Durant, E. L., Winson, M. K., Chhabra, S. R., Williams, P., Macintyre, S. & Stewart, G. S. 1997 Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules. J. Bacteriol. 178, 5271-5281.
203. Swift, S., Lynch, M. J., Fish, L., Kirke, D. F., Tomas, J. M., Stewart, G. S. A. B. & Williams, P. 1999 Quorum sensingdependent regulation and blockade of exoprotease production in Aeromonas hydrophila. Infect. Immun. 67, 5192-5199.
204. Thomsen, R. N. & Kristiansen, M. M. 2001 Three cases of bacteraemia caused by Aeromonas veronii biovar sobria. Scand. J. Infect. Dis. 33, 718-719.
205. Verenkar, M., Naik, V., Rodrigues, S. & Singh, I. 1995 Aeromonas species and Plesiomonas shigelloides in diarrhoea in Goa. Ind. J. Pathol. Microbiol. 38, 169-171.
206. Vivas, J., Razquin, B. E., Lopez-Fierro, P., Naharro, G. & Villena, A. 2004 Correlation between production of acyl homoserine lactones and proteases in an Aeromonas hydrophila aroA live vaccine. Vet. Microbiol. 101, 167-176.
207. Wong, C. Y., Mayrhofer, G., Heuzenroeder, M. W., Atkinson, H. M., Quinn, D. M. & Flower, R. L. 1996 Measurement of virulence of aeromonads using a suckling mouse model of infection. FEMS Immun. Med. Microbol. 15, 233-241.
208. Wong, K. & Buckley, J. T. 1989 Proton motive force involved in protein transport across the outer membrane of Aeromonas hydrophila. Science 246, 654-656.
209. Xanthoudakis, S., Miao, G., Wang, F., Pan, Y. C. & Curran, T. 1992 Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J. 11, 3323-3335.
210. Xu, X. -J., Ferguson,M. R., Popov, V. L., Houston, C.W., Peterson, J.W. & Chopra, A. K. 1998 Role of cytotoxic enterotoxin in Aeromonas- mediated infections: development of transposon and isogenic mutants. Infect. Immun. 66, 3501-3509.
211. Yamada, S., Matsushita, S., Dejsirilet, S. & Kudoh, Y. 1997 Incidence and clinical symptoms of Aeromonas-associated travellers' diarrhoea in Toyko. Epidemiol. Infect. 119, 121-126.
212. Yu, H. B., Srinivasa Rao, P. S., Lee, H. C., Vilches, S., Merino, S., Thomas, J. M. & Leung, K. Y. 2004 A type III secretion system is required for Aeromonas hydrophila AH-1 pathogenesis. Infect. Immun. 72, 1248-1256.
213. Zhang, Y. L., Arakawa, E. & Leung, K. Y. 2002 Novel Aeromonas hydrophila PPD134/91 genes involved in O-antigen and capsule biosynthesis. Infect. Immun. 70, 2326-2335.