Role of a cytotoxic enterotoxin in aeromonas-mediated infections: Development of transposon and isogenic mutants

Infection and Immunity

Volumn 66, Issue 8, 1998, Pages 3501-3509

  Xu, Xin J ^a   Ferguson, M R ^a   Popov, V L ^a   Houston, C W ^a   Peterson, J W ^a   Chopra, A K ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AEROMONAS HYDROPHILA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; CONTROLLED STUDY; ELECTRON MICROSCOPY; INTESTINE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSPOSON;

EID: 0031820463     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.8.3501-3509.1998     Document Type: Article

References (42)

1. Altwegg, M., and H. K. Geiss. 1989. Aeromonas as a human pathogen. Crit. Rev. Microbiol. 16:253-286.
2. Altwegg, M., G. M. Lucchini, J. Luthy-Hottenstein, and M. Rohrbach. 1991. Aeromonas-associated gastroenteritis after consumption of contaminated shrimp. Eur. J. Clin. Microbiol. Infect. Dis. 10:44-45.
3. Anguita, J., L. B. Rodriguez Aparicio, and G. Naharro. 1993. Purification, gene cloning, amino acid sequence analysis, and expression of an extracellular lipase from an Aeromonas hydrophila human isolate. Appl. Environ. Microbiol. 59:2411-2417.
4. Asao, T., Y. Kinoshita, S. Kozaki, T. Uemura, and G. Sakaguchi. 1984. Purification and some properties of Aeromonas hydrophila hemolysin. Infect. Immun. 46:122-127.
5. Austin, B., M. Altwegg, P. J. Gosling, and S. Joseph (ed.). 1996. The genus Aeromonas. John Wiley and Sons, Inc., New York, N.Y.
6. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. Seidman, J. A. Smith, and K. Struhl (ed.). 1989. Current protocols in molecular biology. John Wiley and Sons, Inc., New York, N.Y.
7. Ballard, J., J. Crabtree, B. A. Roe, and R. K. Tweten. 1995. The primary structure of Clostridium septicum alpha-toxin exhibits similarity with that of Aeromonas hydrophila aerolysin. Infect. Immun. 63:340-344.
8. Buchanan, R. L., and S. A. Palumbo. 1985. Aeromonas hydrophila and Aeromonas sobria as potential food poisoning species: a review. J. Food Safety 7:15-29.
9. Chakraborty, T., B. Huhle, H. Bergbauer, and W. Goebel. 1986. Cloning, expression, and mapping of the Aeromonas hydrophila aerolysin gene determinant in Escherichia coli K-12. J. Bacteriol. 167:368-374.
10. Chakraborty, T., B. Huhle, H. Hof, H. Bergbauer, and W. Goebel. 1987. Marker exchange mutagenesis of the aerolysin determinant in Aeromonas hydrophila demonstrates the role of aerolysin in A. hydrophila-associated systemic infections. Infect. Immun. 55:2274-2280.
11. Challapalli, M., B. R. Tesss, D. G. Cunningham, A. K. Chopra, and C. W. Houston. 1988. Aeromonas-associated diarrhea in children. Pediatr. Infect. Dis. J. 7:693-698.
12. Chatterjee, B. D., and K. N. Neogy. 1972. Studies on Aeromonas and Plesiomonas species isolated from cases of choleric diarrhea. Ind. J. Med. Res. 60:520-524.
13. Chopra, A. K., C. W. Houston, and A. Kurosky. 1991. Genetic variation in related cytolytic toxins produced by different species of Aeromonas. FEMS Microbiol. Lett. 78:231-238.
14. Chopra, A. K., C. W. Houston, J. W. Peterson, and G. F. Jin. 1993. Cloning, expression, and sequence analysis of a cytolytic enterotoxin gene from Aeromonas hydrophila. Can. J. Microbiol. 39:513-523.
15. Donnenberg, M. S., and J. B. Kaper. 1991. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect. Immun. 59:4310-4317.
16. Ferguson, M. R., X.-J. Xu, C. W. Houston, J. W. Peterson, and A. K. Chopra. 1995. Amino-acid residues involved in biological functions of the cytolytic enterotoxin from Aeromonas hydrophila. Gene 156:79-83.
17. Ferguson, M. R., X.-J. Xu, C. W. Houston, J. W. Peterson, D. H. Coppenhaver, V. L. Popov, and A. K. Chopra. 1997. Hyperproduction, purification, and mechanism of action of the cytotoxic enterotoxin produced by Aeromonas hydrophila. Infect. Immun. 65:4299-4308.
18. Gracey, M., J. Robinson, and V. Burke. 1982. Aeromonas-associated gastroenteritis. Lancet ii:1304-1306.
19. Green, M. J., and J. T. Buckley. 1990. Site-directed mutagenesis of the hole-forming toxin aerolysin: studies on the roles of histidines in receptor binding and oligomerization of the monomer. Biochemistry 29:2177-2180.
20. Harayama, S., M. Tsuda, and T. Lino. 1980. High frequency mobilization of the chromosome of Escherichia coli by a mutant of plasmid RP4 temperature-sensitive for maintenance. Mol. Gen. Genet. 180:47-56.
21. Hirono, I., and T. Aoki. 1993. Cloning and characterization of three hemolysin genes from Aeromonas salmonicida. Microb. Pathog. 15:269-282.
22. Hossain, M. A., K. M. Rahman, S. M. Asna, Z. Rahim, T. Hussain, and M. R. Miah. 1992. Incidence of Aeromonas isolated from diarrhoeal children and study of some virulence factors in the isolates. Bangladesh Med. Res. Counc. Bull. 18:61-67.
23. Howard, S. P., and J. T. Buckley. 1986. Molecular cloning and expression in Escherichia coli of the structural gene for the hemolytic toxin aerolysin from Aeromonas hydrophila. Mol. Gen. Genet. 204:289-295.
24. Howard, S. P., W. J. Garland, M. J. Green, and J. T. Buckley. 1987. Nucleotide sequence of the gene for the hole-forming toxin aerolysin of Aeromonas hydrophila. J. Bacteriol. 169:2869-2871.
25. Hur, T., K. C. Cheng, and J. M. Hsieh. 1995. Aeromonas hydrophila lung abscess in a previously healthy man. Scand. J. Infect. Dis. 27:295.
26. Husslein, V., B. Huhle, T. Jarchau, R. Lurz, W. Goebel, and T. Chakraborty. 1988. Nucleotide sequence and transcriptional analysis of the AerCaerA region of Aeromonas sobria encoding aerolysin and its regulatory region. Mol. Microbiol. 2:507-517.
27. Jin, G.-F., and C. W. Houston. 1992. Effect of Aeromonas hydrophila enterotoxins on function of mouse phagocytes. Dig. Dis. Sci. 37:1697-1703.
28. Keusch, G. T., and S. T. Donta. 1975. Classification of enterotoxins on the basis of activity in cell culture. J. Infect. Dis. 131:58-63.
29. Kohashi, T., H. Sakai, F. Marumo, and C. Sato. 1995. Aeromonas sobria infection with severe muscle degeneration in a patient with alcoholic liver cirrhosis. Am. J. Gastroenterol. 90Z:2234-2235.
30. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
31. Lin, S.-H., S.-D. Shieh, Lin, Y. F. Lin, E. De Brauwer, H. W. Van Landuyt, B. Gordts, and J. R. Boelaert. 1996. Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine. Am. J. Kidney Dis. 27:733-735.
32. Ljungh, A., and T. Kronevi. 1982. Aeromonas hydrophila toxins-intestinal fluid accumulation and mucosal injury in animal models. Toxicon 20:397-407.
33. Mani, S., M. Sadigh, and V. T. Adriole. 1995. Clinical spectrum of Aeromonas hydrophila infections: report of 11 cases in a community hospital and review. Infect. Dis. Lin. Pract. 4:79-86.
34. Nelson, K. L., S. M. Raja, and J. T. Buckley. 1997. The glycosylphosphatidylinositol-anchored surface glycoprotein Thy-1 is a receptor for the channel-forming toxin aerolysin. J. Biol. Chem. 272:12170-12174.
35. 2-activating protein and idiopathic inflammatory bowel disease. Gut 39:698-704.
36. Quandt, J., and M. F. Hynes. 1993. Versatile suicide vectors which allow direct selection for gene replacement in gram-negative bacteria. Gene 127: 15-21.
37. Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
38. Rella, M., A. Mercenier, and D. Haas. 1985. Transposon insertion mutagenesis of Pseudomonas aeruginosa with a Tn5 derivative: application to physical mapping of the arc gene cluster. Gene 33:293-303.
39. Rose, J. M., C. W. Houston, and A. Kurosky. 1989. Bioactivity and immu-nological characterization of a cholera toxin-cross-reactive cytolytic enterotoxin from Aeromonas hydrophila. Infect. Immun. 57:1170-1176.
40. Rose, J. M., C. W. Houston, D. H. Coppenhaver, J. D. Dixon, and A. Kurosky. 1989. Purification and chemical characterization of a cholera toxin-cross-reactive cytolytic enterotoxin produced by a human isolate of Aeromonas hydrophila. Infect. Immun. 57:1165-1169.
41. Welch, R. A., and S. Falkow. 1984. Characterization of Escherichia coli hemolysin conferring quantitative differences in virulence. Infect. Immun. 43:156-161.
42. Wright, A. C., and J. G. Morris. 1991. The extracellular cytolysin of Vibrio vulnificus: inactivation and relationship to virulence in mice. Infect. Immun. 59:192-197.