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Volumn 84, Issue 7, 2010, Pages 3270-3279

Breadth of neutralizing antibodies elicited by stable, homogeneous Clade A and Clade C HIV-1 gp140 envelope trimers in guinea pigs

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; IMMUNOGLOBULIN G; NEUTRALIZING ANTIBODY; PRIMER DNA;

EID: 77949370078     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02252-09     Document Type: Article
Times cited : (82)

References (41)
  • 2
    • 53349160053 scopus 로고    scopus 로고
    • Challenges in the development of an HIV-1 vaccine
    • Barouch, D. H. 2008. Challenges in the development of an HIV-1 vaccine. Nature 455:613-619.
    • (2008) Nature , vol.455 , pp. 613-619
    • Barouch, D.H.1
  • 3
    • 33947590277 scopus 로고    scopus 로고
    • A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120
    • Beddows, S., M. Franti, A. K. Dey, M. Kirschner, S. P. Iyer, D. C. Fisch, T. Ketas, E. Yuste, R. C. Desrosiers, P. J. Klasse, P. J. Maddon, W. C. Olson, and J. P. Moore. 2007. A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120. Virology 360:329-340.
    • (2007) Virology , vol.360 , pp. 329-340
    • Beddows, S.1    Franti, M.2    Dey, A.K.3    Kirschner, M.4    Iyer, S.P.5    Fisch, D.C.6    Ketas, T.7    Yuste, E.8    Desrosiers, R.C.9    Klasse, P.J.10    Maddon, P.J.11    Olson, W.C.12    Moore, J.P.13
  • 4
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
    • Berger, E. A., P. M. Murphy, and J. M. Farber. 1999. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17:657-700.
    • (1999) Annu. Rev. Immunol , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 6
    • 0033985999 scopus 로고    scopus 로고
    • A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure
    • Binley, J. M., R. W. Sanders, B. Clas, N. Schuelke, A. Master, Y. Guo, F. Kajumo, D. J. Anselma, P. J. Maddon, W. C. Olson, and J. P. Moore. 2000. A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure. J. Virol. 74:627-643.
    • (2000) J. Virol , vol.74 , pp. 627-643
    • Binley, J.M.1    Sanders, R.W.2    Clas, B.3    Schuelke, N.4    Master, A.5    Guo, Y.6    Kajumo, F.7    Anselma, D.J.8    Maddon, P.J.9    Olson, W.C.10    Moore, J.P.11
  • 7
    • 33744923672 scopus 로고    scopus 로고
    • HIV-1 Envgp140 trimers elicit neutralizing antibodies without efficient induction of conformational antibodies
    • Bower, J. F., Y. Li, R. Wyatt, and T. M. Ross. 2006. HIV-1 Envgp140 trimers elicit neutralizing antibodies without efficient induction of conformational antibodies. Vaccine 24:5442-5451.
    • (2006) Vaccine , vol.24 , pp. 5442-5451
    • Bower, J.F.1    Li, Y.2    Wyatt, R.3    Ross, T.M.4
  • 8
    • 4444342579 scopus 로고    scopus 로고
    • Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d
    • Bower, J. F., X. Yang, J. Sodroski, and T. M. Ross. 2004. Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d. J. Virol. 78:4710-4719.
    • (2004) J. Virol , vol.78 , pp. 4710-4719
    • Bower, J.F.1    Yang, X.2    Sodroski, J.3    Ross, T.M.4
  • 9
    • 63549137349 scopus 로고    scopus 로고
    • Neutralizing antibody responses to subtype B and C adjuvanted HIV envelope protein vaccination in rabbits
    • Burke, B., V. R. Gomez-Roman, Y. Lian, Y. Sun, E. Kan, J. Ulmer, I. K. Srivastava, and S. W. Barnett. 2009. Neutralizing antibody responses to subtype B and C adjuvanted HIV envelope protein vaccination in rabbits. Virology 387:147-156.
    • (2009) Virology , vol.387 , pp. 147-156
    • Burke, B.1    Gomez-Roman, V.R.2    Lian, Y.3    Sun, Y.4    Kan, E.5    Ulmer, J.6    Srivastava, I.K.7    Barnett, S.W.8
  • 11
    • 0025932101 scopus 로고    scopus 로고
    • Carrow, E. W., L. K. Vujcic, W. L. Glass, K. B. Seamon, S. C. Rastogi, R. M. Hendry, R. Boulos, N. Nzila, and G. V. Quinnan, Jr. 1991. High prevalence of antibodies to the gp120 V3 region principal neutralizing determinant of HIV-1MN in sera from Africa and the Americas. AIDS Res. Hum. Retroviruses 7:831-838.
    • Carrow, E. W., L. K. Vujcic, W. L. Glass, K. B. Seamon, S. C. Rastogi, R. M. Hendry, R. Boulos, N. Nzila, and G. V. Quinnan, Jr. 1991. High prevalence of antibodies to the gp120 V3 region principal neutralizing determinant of HIV-1MN in sera from Africa and the Americas. AIDS Res. Hum. Retroviruses 7:831-838.
  • 12
    • 0034634548 scopus 로고    scopus 로고
    • Expression, purification, and characterization of gp160e, the soluble, trimeric ectodomain of the simian immunodeficiency virus envelope glycoprotein, gp160
    • Chen, B., G. Zhou, M. Kim, Y. Chishti, R. E. Hussey, B. Ely, J. J. Skehel, E. L. Reinherz, S. C. Harrison, and D. C. Wiley. 2000. Expression, purification, and characterization of gp160e, the soluble, trimeric ectodomain of the simian immunodeficiency virus envelope glycoprotein, gp160. J. Biol. Chem. 275:34946-34953.
    • (2000) J. Biol. Chem , vol.275 , pp. 34946-34953
    • Chen, B.1    Zhou, G.2    Kim, M.3    Chishti, Y.4    Hussey, R.E.5    Ely, B.6    Skehel, J.J.7    Reinherz, E.L.8    Harrison, S.C.9    Wiley, D.C.10
  • 15
    • 34249827906 scopus 로고    scopus 로고
    • Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: Antigenicity, biophysics, and immunogenicity
    • Dey, B., M. Pancera, K. Svehla, Y. Shu, S. H. Xiang, J. Vainshtein, Y. Li, J. Sodroski, P. D. Kwong, J. R. Mascola, and R. Wyatt. 2007. Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity. J. Virol. 81:5579-5593.
    • (2007) J. Virol , vol.81 , pp. 5579-5593
    • Dey, B.1    Pancera, M.2    Svehla, K.3    Shu, Y.4    Xiang, S.H.5    Vainshtein, J.6    Li, Y.7    Sodroski, J.8    Kwong, P.D.9    Mascola, J.R.10    Wyatt, R.11
  • 16
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn, N. M., D. N. Forthal, C. D. Harro, F. N. Judson, K. H. Mayer, and M. F. Para. 2005. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J. Infect. Dis. 191:654-665.
    • (2005) J. Infect. Dis , vol.191 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3    Judson, F.N.4    Mayer, K.H.5    Para, M.F.6
  • 20
    • 13144302861 scopus 로고    scopus 로고
    • Comparison of HIV type 1 ADA gp120 monomers versus gp140 trimers as immunogens for the induction of neutralizing antibodies
    • Kim, M., Z. S. Qiao, D. C. Montefiori, B. F. Haynes, E. L. Reinherz, and H. X. Liao. 2005. Comparison of HIV type 1 ADA gp120 monomers versus gp140 trimers as immunogens for the induction of neutralizing antibodies. AIDS Res. Hum. Retroviruses 21:58-67.
    • (2005) AIDS Res. Hum. Retroviruses , vol.21 , pp. 58-67
    • Kim, M.1    Qiao, Z.S.2    Montefiori, D.C.3    Haynes, B.F.4    Reinherz, E.L.5    Liao, H.X.6
  • 22
    • 31144451337 scopus 로고    scopus 로고
    • Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants
    • Li, Y., K. Svehla, N. L. Mathy, G. Voss, J. R. Mascola, and R. Wyatt. 2006. Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants. J. Virol. 80:1414-1426.
    • (2006) J. Virol , vol.80 , pp. 1414-1426
    • Li, Y.1    Svehla, K.2    Mathy, N.L.3    Voss, G.4    Mascola, J.R.5    Wyatt, R.6
  • 24
    • 23244467373 scopus 로고    scopus 로고
    • Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines
    • Mascola, J. R., P. D'Souza, P. Gilbert, B. H. Hahn, N. L. Haigwood, L. Morris, C. J. Petropoulos, V. R. Polonis, M. Sarzotti, and D. C. Montefiori. 2005. Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines. J. Virol. 79:10103-10107.
    • (2005) J. Virol , vol.79 , pp. 10103-10107
    • Mascola, J.R.1    D'Souza, P.2    Gilbert, P.3    Hahn, B.H.4    Haigwood, N.L.5    Morris, L.6    Petropoulos, C.J.7    Polonis, V.R.8    Sarzotti, M.9    Montefiori, D.C.10
  • 25
    • 38049094546 scopus 로고    scopus 로고
    • Antibody-based HIV-1 vaccines: Recent developments and future directions
    • Montefiori, D., Q. Sattentau, J. Flores, J. Esparza, and J. Mascola. 2007. Antibody-based HIV-1 vaccines: recent developments and future directions. PLoS Med. 4:e348.
    • (2007) PLoS Med , vol.4
    • Montefiori, D.1    Sattentau, Q.2    Flores, J.3    Esparza, J.4    Mascola, J.5
  • 26
    • 60349089294 scopus 로고    scopus 로고
    • Measuring HIV neutralization in a luciferase reporter gene assay
    • Montefiori, D. C. 2009. Measuring HIV neutralization in a luciferase reporter gene assay. Methods Mol. Biol. 485:395-405.
    • (2009) Methods Mol. Biol , vol.485 , pp. 395-405
    • Montefiori, D.C.1
  • 28
    • 0023770970 scopus 로고
    • Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies
    • Nara, P. L., W. G. Robey, S. W. Pyle, W. C. Hatch, N. M. Dunlop, J. W. Bess, Jr., J. C. Kelliher, L. O. Arthur, and P. J. Fischinger. 1988. Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies. J. Virol. 62:2622-2628.
    • (1988) J. Virol , vol.62 , pp. 2622-2628
    • Nara, P.L.1    Robey, W.G.2    Pyle, S.W.3    Hatch, W.C.4    Dunlop, N.M.5    Bess Jr., J.W.6    Kelliher, J.C.7    Arthur, L.O.8    Fischinger, P.J.9
  • 30
    • 33646146379 scopus 로고    scopus 로고
    • GP120: Target for neutralizing HIV-1 antibodies
    • Pantophlet, R., and D. R. Burton. 2006. GP120: target for neutralizing HIV-1 antibodies. Annu. Rev. Immunol. 24:739-769.
    • (2006) Annu. Rev. Immunol , vol.24 , pp. 739-769
    • Pantophlet, R.1    Burton, D.R.2
  • 31
    • 33845433434 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    • Pitisuttithum, P., P. Gilbert, M. Gurwith, W. Heyward, M. Martin, F. van Griensven, D. Hu, J. W. Tappero, and K. Choopanya. 2006. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J. Infect. Dis. 194:1661-1671.
    • (2006) J. Infect. Dis , vol.194 , pp. 1661-1671
    • Pitisuttithum, P.1    Gilbert, P.2    Gurwith, M.3    Heyward, W.4    Martin, M.5    van Griensven, F.6    Hu, D.7    Tappero, J.W.8    Choopanya, K.9
  • 35
    • 47749129289 scopus 로고    scopus 로고
    • Improved induction of antibodies against key neutralizing epitopes by human immunodeficiency virus type 1 gp120 DNA prime-protein boost vaccination compared to gp120 protein-only vaccination
    • Vaine, M., S. Wang, E. T. Crooks, P. Jiang, D. C. Montefiori, J. Binley, and S. Lu. 2008. Improved induction of antibodies against key neutralizing epitopes by human immunodeficiency virus type 1 gp120 DNA prime-protein boost vaccination compared to gp120 protein-only vaccination. J. Virol. 82:7369-7378.
    • (2008) J. Virol , vol.82 , pp. 7369-7378
    • Vaine, M.1    Wang, S.2    Crooks, E.T.3    Jiang, P.4    Montefiori, D.C.5    Binley, J.6    Lu, S.7
  • 36
    • 0027991518 scopus 로고
    • The majority of neutralizing Abs in HIV-1-infected patients recognize linear V3 loop sequences. Studies using HIV-1MN multiple antigenic peptides
    • Vogel, T., R. Kurth, and S. Norley. 1994. The majority of neutralizing Abs in HIV-1-infected patients recognize linear V3 loop sequences. Studies using HIV-1MN multiple antigenic peptides. J. Immunol. 153:1895-1904.
    • (1994) J. Immunol , vol.153 , pp. 1895-1904
    • Vogel, T.1    Kurth, R.2    Norley, S.3
  • 37
    • 70349887757 scopus 로고    scopus 로고
    • Walker, L. M., S. K. Phogat, P. Y. Chan-Hui, D. Wagner, P. Phung, J. L. Goss, T. Wrin, M. D. Simek, S. Fling, J. L. Mitcham, J. K. Lehrman, F. H. Priddy, O. A. Olsen, S. M. Frey, P. W. Hammond, G. Miiro, J. Serwanga, A. Pozniak, D. McPhee, O. Manigart, L. Mwananyanda, E. Karita, A. Inwoley, W. Jaoko, J. Dehovitz, L. G. Bekker, P. Pitisuttithum, R. Paris, S. Allen, S. Kaminsky, T. Zamb, M. Moyle, W. C. Koff, P. Poignard, and D. R. Burton. 2009. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326:285-289.
    • Walker, L. M., S. K. Phogat, P. Y. Chan-Hui, D. Wagner, P. Phung, J. L. Goss, T. Wrin, M. D. Simek, S. Fling, J. L. Mitcham, J. K. Lehrman, F. H. Priddy, O. A. Olsen, S. M. Frey, P. W. Hammond, G. Miiro, J. Serwanga, A. Pozniak, D. McPhee, O. Manigart, L. Mwananyanda, E. Karita, A. Inwoley, W. Jaoko, J. Dehovitz, L. G. Bekker, P. Pitisuttithum, R. Paris, S. Allen, S. Kaminsky, T. Zamb, M. Moyle, W. C. Koff, P. Poignard, and D. R. Burton. 2009. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326:285-289.
  • 38
    • 33746651142 scopus 로고    scopus 로고
    • Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E
    • Wang, S., R. Pal, J. R. Mascola, T. H. Chou, I. Mboudjeka, S. Shen, Q. Liu, S. Whitney, T. Keen, B. C. Nair, V. S. Kalyanaraman, P. Markham, and S. Lu. 2006. Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E. Virology 350:34-47.
    • (2006) Virology , vol.350 , pp. 34-47
    • Wang, S.1    Pal, R.2    Mascola, J.R.3    Chou, T.H.4    Mboudjeka, I.5    Shen, S.6    Liu, Q.7    Whitney, S.8    Keen, T.9    Nair, B.C.10    Kalyanaraman, V.S.11    Markham, P.12    Lu, S.13
  • 39
    • 0036231093 scopus 로고    scopus 로고
    • Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin
    • Yang, X., J. Lee, E. M. Mahony, P. D. Kwong, R. Wyatt, and J. Sodroski. 2002. Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin. J. Virol. 76:4634-4642.
    • (2002) J. Virol , vol.76 , pp. 4634-4642
    • Yang, X.1    Lee, J.2    Mahony, E.M.3    Kwong, P.D.4    Wyatt, R.5    Sodroski, J.6
  • 40
    • 0035955695 scopus 로고    scopus 로고
    • Expression, purification, and characterization of recombinant HIV gp140. The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer
    • Zhang, C. W., Y. Chishti, R. E. Hussey, and E. L. Reinherz. 2001. Expression, purification, and characterization of recombinant HIV gp140. The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer. J. Biol. Chem. 276: 39577-39585.
    • (2001) J. Biol. Chem , vol.276 , pp. 39577-39585
    • Zhang, C.W.1    Chishti, Y.2    Hussey, R.E.3    Reinherz, E.L.4
  • 41
    • 39449107834 scopus 로고    scopus 로고
    • Focusing the immune response on the V3 loop, a neutralizing epitope of the HIV-1 gp120 envelope
    • Zolla-Pazner, S., S. S. Cohen, C. Krachmarov, S. Wang, A. Pinter, and S. Lu. 2008. Focusing the immune response on the V3 loop, a neutralizing epitope of the HIV-1 gp120 envelope. Virology 372:233-246.
    • (2008) Virology , vol.372 , pp. 233-246
    • Zolla-Pazner, S.1    Cohen, S.S.2    Krachmarov, C.3    Wang, S.4    Pinter, A.5    Lu, S.6


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