Chemical and structural investigation of lipid nanoparticles: Drug-lipid interaction and molecular distribution

Nanotechnology

Volumn 21, Issue 12, 2010, Pages

  Anantachaisilp, Suranan ^a   Smith, Siwaporn Meejoo ^a   Treetong, Alongkot ^b   Pratontep, Sirapat ^c   Puttipipatkhachorn, Satit ^a   Ruktanonchai, Uracha Rungsardthong ^b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

^c KING MONGKUT'S INSTITUTE OF TECHNOLOGY LADKRABANG   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL RETENTION; CRYSTALLINITIES; DRUG DELIVERY SYSTEM; HIGH PRESSURE HOMOGENIZATION; HIGH RESOLUTION; LIPID CONTENT; LIPID NANOPARTICLES; MEDIUM CHAIN TRIGLYCERIDES; MOLECULAR DISTRIBUTION; ORYZANOL; PHASE-SEPARATED STRUCTURES; POWDER X RAY DIFFRACTION; PROTON NUCLEAR MAGNETIC RESONANCE; RAMAN SPECTROSCOPIC; RELEASE CHARACTERISTICS; SIMPLE MODEL; STRUCTURAL INVESTIGATION;

ATOMIC FORCE MICROSCOPY; DRUG DELIVERY; DRUG INTERACTIONS; INDICATORS (CHEMICAL); NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTON CORRELATION SPECTROSCOPY; RAMAN SPECTROSCOPY; RESONANCE; X RAY DIFFRACTION;

LIQUIDS;

CETYL PALMITATE; DRUG CARRIER; GAMMA ORYZANOL; GAMMA-ORYZANOL; NANOPARTICLE; PALMITIC ACID DERIVATIVE; PHENYLPROPIONIC ACID DERIVATIVE; TRIACYLGLYCEROL;

ANALYSIS OF VARIANCE; AREA UNDER THE CURVE; ARTICLE; ATOMIC FORCE MICROSCOPY; CHEMISTRY; DRUG DELIVERY SYSTEM; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; POWDER DIFFRACTION; RAMAN SPECTROMETRY; THERMODYNAMICS;

ANALYSIS OF VARIANCE; AREA UNDER CURVE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; MICROSCOPY, ATOMIC FORCE; NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PALMITATES; PARTICLE SIZE; PHENYLPROPIONATES; POWDER DIFFRACTION; SPECTRUM ANALYSIS, RAMAN; THERMODYNAMICS; TRIGLYCERIDES;

EID: 77949367139     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/21/12/125102     Document Type: Article

References (39)

1. Hanafy A, Spahn-Langguth H, Vergnault G, Grenier P, Tubic Grozdanis M, Lenhardt T and Langguth P 2007 Pharmacokinetic evaluation of oral fenofibrate nanosuspensions and SLN in comparison to conventional suspensions of micronized drug Adv. Drug Deliv. Rev. 59 419-26
2. Souto E B, Wissing S A, Barosa C M and Müller R H 2004 Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery Int. J. Pharm. 278 71-7
3. Attama A A and Muller-Goymann C C 2007 Investigation of surface-modified solid lipid nanocontainers formulated with a heterolipid-templated homolipid Int. J. Pharm. 334 179-89
4. Attama A A, Schicke B C, Paepenmuller T and Muller-Goymann C C 2007 Solid lipid nanodispersions containing mixed lipid core and a polar heterolipid: characterization Eur. J. Pharm. Biopharm. 67 48-57
5. Castelli F, Paglia C, Sarpietro M G, Rizza L and Bonina F 2005 Characterization of indomethacin-loaded lipid nanoparticles by differential scanning calorimetry Int. J. Pharm. 304 231-8
6. Muller R H, Radtke M and Wissing S A 2002 Nanostructured lipid matrices for improved microencapsulation of drugs Int. J. Pharm. 242 121-8
7. Müller R H, Mader K and Gohla S 2000 Solid lipid nanoparticles (SLN) for controlled active delivery-a review of the state of art Eur. J. Pharm. Biopharm. 50 161-77
8. Muller R H and Ruge S A 1998 Solid lipid nanoparticles (SLN) for controlled drug delivery Submicron Emulsion in Drug Targeting and Delivery (Amsterdam: Harwood Academic) pp219-34
9. Gulati M, Grover M, Singh S and Singh M 1998 Lipophilic drug derivatives in liposomes Int. J. Pharm. 165 129-68
10. Wissing S A, Kayser O and Müller R H 2004 Solid lipid nanoparticles for parenteral drug delivery Adv. Drug Deliv. Rev. 56 1257-72
11. Yuan H, Wang L L, Du Y Z, You J, Hu F Q and Zeng S 2007 Preparation and characteristics of nanostructured lipid carriers for control-releasing progesterone by melt-emulsification Colloids Surf. B 60 174-9
12. Teeranachaideekul V, Boonme P, Souto E B, Muller R H and Junyaprasert V B 2008 Influence of oil content on physicochemical properties and skin distribution of Nile red-loaded NLC J. Control. Release 128 134-41
13. Mehnert W and Mader K 2001 Solid lipid nanoparticles: production, characterization and applications Adv. Drug Deliv. Rev. 47 165-96
14. Saupe A, Gardon K C and Rades T 2006 Structural investigations on nanoemulsion, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy Int. J. Pharm. 314 56-62
15. Attama A A and Muller-Goymann C C 2008 Effect of beeswax modification on the lipid matrix and solid lipid nanoparticle crystallinity Colloids Surf. A 315 189-95
16. Jenning V, Thunemann A F and Gohla S H 2000 Characterisation of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids Int. J. Pharm. 199 167-77
17. 10- development, physicochemical characterization and in vitro release studies Eur. J. Pharm. Biopharm. 67 141-8
18. Hu F Q, Jiang S P, Du Y Z, Yuan H, Ye Y Q and Zeng S 2005 Preparation and characterization of steric acid nanostructured lipid carriers by solvent diffusion method in an aqueous system Colloids Surf. B 45 167-73
19. Hu F Q, Jiang S P, Du Y Z, Yuan H, Ye Y Q and Zeng S 2006 Preparation and characteristics of monostearin nanostructured lipid carriers Int. J. Pharm. 314 83-9
20. Ruktanonchai U, Limpakdee S, Meejoo S, Sakulkhu U, Bunyapraphatsara N, Junyaprasert V and Puttipipatkhachorn S 2008 The effect of cetyl palmitate crystallinity on physical properties of gamma-oryzanol encapsulated in solid lipid nanoparticles Nanotechnology 19 1-10
21. Schubert M A, Harms M and Muller-Goymann C C 2006 Structural investigations on lipid nanoparticles containing high amounts of lecithin Eur. J. Pharm. Sci. 27 226-36
22. Ruktanonchai U, Sakulkhu U, Bejrapha P, Opanasopit P, Bunyapraphatsara N, Junyaprasert V and Puttipipatkhachorn S 2009 Effect of lipid types on physicochemical characteristics, stability and antioxidant activity of gamma-oryzanol-loaded lipid nanoparticles J. Microencapsul. 26 614-26
23. Freitas C and Muller R H 1999 Correlation between long-term stability of solid lipid nanoparticles (SLN) and crystallinity of the lipid phase Eur. J. Pharm. Biopharm. 47 125-32
24. Hagemann J W 1998 Thermal behaviour and polymorphism ofacylglycerides Crystallization and Polymorphism of Fats and Fatty Acids ed N Garti and K Sato (New York: Dekker) pp9-96
25. Radtke M and Muller R H 2001 NLC-nanostructured lipid carriers: the new generation of lipid drug carriers New Drugs: Nanotechnology 2 48-52
26. 1H-NMR study Int. J. Pharm. 205 15-21
27. Jores K, Mehnert W and Mader K 2003 Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: a nuclear magnetic resonance and electron spin resonance study Pharm. Res. 20 1274-83
28. Wartewig S and Neubert R H H 2005 Pharmaceutical applications of Mid-IR and Raman spectroscopy Adv. Drug Deliv. Rev. 57 1144-70
29. Faruyama N, Hasegawa S, Hamaura T, Yada S, Nakagami H, Yonemochi E and Terada K 2008 Evaluation of solid dispersions on a molecular level by the Raman mapping technique Int. J. Pharm. 361 12-8
30. Hou D Z, Xie C S, Huang K J and Zhu C H 2003 The production and characteristics of solid lipid nanoparticles (SLNs) Biomaterials 24 1781-5
31. Gowariker V R, Viswanathan N V and Sreedhar J 1986 Crystallinity in polymers Polymer Science vol 173 (New York: Wiley)
32. Jores K, Mehnert W, Drechsler M, Bunjes H, Johann C and Mader K 2004 Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy J. Control. Release 95 217-27
33. 1) Int. J. Pharm. 295 261-8
34. Souto E B and Müller R H 2005 SLN and NLC for topical delivery of Ketoconazole J. Microencapsul. 22 501-10
35. Turner Y T A, Roberts C J and Davies M C 2007 Scanning probe microscopy in the field of drug delivery Adv. Drug Deliv. Rev. 59 1453-73
36. Sun W, Mao S, Mei D and Kissel T 2008 Self-assemble polyelectrolyte nanocomplexes between chitosan derivatives and enoxaparin Eur. J. Pharmaceut. Biopharmaceut. 69 417-25
37. Ruozi B, Tosi G, Leo E and Vandelli M A 2007 Application of atomic force microscopy to characterize liposomes as drug and gene carriers Talanta 73 12-22
38. Holzgrabe U, Diehl B W K and Wawer I 1998 NMR spectroscopy in pharmacy J. Pharm. Biomed. Anal. 17 557-616
39. Jores K, Haberland A, Wartewig S, Mader K and Mehnert W 2005 Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy Pharm. Res. 22 1887-97