Evaluation of solid dispersions on a molecular level by the Raman mapping technique

International Journal of Pharmaceutics

Volumn 361, Issue 1-2, 2008, Pages 12-18

  Furuyama, Naho ^a   Hasegawa, Susumu ^a   Hamaura, Takeshi ^a   Yada, Shuichi ^a   Nakagami, Hiroaki ^a   Yonemochi, Etsuo ^b   Terada, Katsuhide ^b  

^a DAIICHI SANKYO CO   (Japan)

^b TOHO UNIVERSITY   (Japan)

Author keywords

Raman mapping technique; Raman spectroscopy; Solid dispersion; Troglitazone

Indexed keywords

POVIDONE; TROGLITAZONE;

ANALYTIC METHOD; ARTICLE; CRYSTAL; DIASTEREOISOMER; EVALUATION; ISOMER; MELTING POINT; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SOLID; X RAY POWDER DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; CHROMANS; CRYSTALLIZATION; DOSAGE FORMS; DRUG CARRIERS; SPECTRUM ANALYSIS, RAMAN; STEREOISOMERISM; THIAZOLIDINEDIONES; TRANSITION TEMPERATURE;

EID: 47949114409     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.05.009     Document Type: Article

References (26)

1. Auer M.E., Griesser U.J., and Sawatzki J. Qualitative and quantitative study of polymorphic forms in drug formulations by near infrared FT-Raman spectroscopy. J. Mol. Struct. 661-662 (2003) 307-317
2. Broman E., Khoo C., and Taylor L.S. A comparison of alternative polymer excipients and processing methods for masking solid dispersions of a poorly water soluble drug. Int. J. Pharm. 222 (2001) 139-151
3. Chiou W.L., and Riegelman S. Pharmaceutical applications of solid dispersion systems. J. Pharm. Sci. 60 (1971) 1281-1302
4. Cambell Roberts S.N., Williams A.C., Grimsey I.M., and Booth S.W. Quantitative analysis of mannitol polymorphs. FT-Raman spectroscopy. J. Pharm. Biomed. Anal. 28 (2002) 1135-1147
5. Elamin A.A., Alderborn G., and Ahlneck C. The effect of pre-compaction processing and storage conditions on powder and compaction properties of some crystalline materials. Int. J. Pharm. 108 (1994) 213-224
6. Fitzpatrick S., McCabe J.F., Petts C.R., and Booth S.W. Effects of moisture on polyvinylpyrrolidone in accelerated stability testing. Int. J. Pharm. 246 (2002) 143-151
7. Gift A.D., and Taylor L.S. Hyphenation of Raman spectroscopy with gravimetric analysis to interrogate water-solid interactions in pharmaceutical systems. J. Pharm. Biomed. Anal. 43 (2007) 14-23
8. Gohel M.C., and Patel L.D. Processing of Nimesulide-PEG 400-PG-PVP solid dispersions: preparation, characterization, and vitro dissolution. Drug. Dev. Ind. Pharm. 29 (2003) 299-310
9. Grunenberg A., Keil B., and Henck J.O. Polymorphism in binary mixtures, as exemplified by nimodipine. Int. J. Pharm. 118 (1995) 11-21
10. Hamaura T., and Newton M. Interaction between water and poly(vinylpyrrolidone) containing polyechylene glycol. J. Pharm. Sci. 88 (1999) 1228-1233
11. Hancock B.C., and Zografi G. Characteristics and significance of the amorphous state in pharmaceutical systems. J. Pharm. Sci. 86 (1997) 1-12
12. Hasegawa S., Hamaura T., Furuyama N., Horikawa S., Kusai A., Yonemochi E., and Terada K. Uniformity and physical states of troglitazone in solid dispersions determined by electron probe microanalysis and microthermal analysis. Int. J. Pharm. 280 (2004) 39-46
13. Hasegawa S., Hamaura T., Furuyama N., Kusai A., Yonemochi E., and Terada K. Effects of water content in physical mixture and heating temperature on crystallinity of troglitazone-PVP K30 solid dispersions prepared by closed melting method. Int. J. Pharm. 302 (2005) 103-112
14. Leuner C., and Dressman J. Improving drug solubility for oral delivery using solid dispersions. Eur. J. Pharm. Biopharm. 50 (2000) 47-60
15. Liu C., and Desai K.G. Characteristics of rofecoxib-polyethylene glycol 4000 solid dispersions and tablets based on solid dispersions. Pharm. Dev. Technol. 10 (2005) 467-477
16. Murphy B.M., Prescott S.W., and Larson I. Measurement of lactose crystallinity using Raman spectroscopy. J. Pharm. Biomed. Anal. 38 (2005) 186-190
17. Savolainen M., Herder J., Khoo C., Lövqvist K., Dahlqvist C., Glad H., and Juppo A.M. Evaluation of polar lipid-hydrophilic polymer microparticles. Int. J. Pharm. 262 (2003) 47-62
18. Sheikhzadeh M., Rohani S., Jutan A., Manifar T., Murthy K., and Horne S. Solid-state characterization of buspirone hydrochloride polymorphs. Pharm. Res. 23 (2006) 1043-1050
19. Suzuki N., Kasahara K., Hasegawa H., and Kawasaki T. Physical property of troglitazone, an equal mixture of four stereoisomers. Int. J. Pharm. 248 (2002) 71-80
20. Suzuki N., Kasahara K., Watanabe Y., Kinoshita S., Hasegawa H., and Kawasaki T. Solid-state variation of troglitazone drug substance by using a different recrystallization method. Drug. Dev. Ind. Pharm. 29 7 (2003) 805-812
21. Spiegeleer B.D., Seggers D., Wieme R., Schaucroeck J., Verpoort F., Slegers G., and Vooren L.V. Determination of the relative amounts of three crystaL-pairs of a benzimidazole drug in complex finished formulations by FT-Raman spectroscopy. J. Pharm. Biomed. Anal. 39 (2005) 275-280
22. Taylor L.S., and Zografi G. Spectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular dispersions. Pharm. Res. 14 (1997) 1691-1698
23. Taylor L.S., and Langkilde F.W. Evaluation of solid-state forms present in tablets by Raman spectroscopy. J. Pharm. Sci. 89 (2000) 1342-1353
24. Thybo P., Kristensen J., and Hovgaard L. Characterization and physical stability of tolfenamic acid-PVP K30 solid dispersions. Pharm. Dev. Technol. 12 (2007) 43-53
25. Ward S., Perkins M., Zhang J., Roberts C.J., Madden C.E., Luk S.Y., Patel N., and Ebbens S.J. Identifying and mapping surface amorphous domains. Pharm. Res. 22 (2005) 1195-1202
26. Wilkström H., Marsac P.J., and Taylor L.S. In-line monitoring of hydrate formulation during wet granulation using Raman spectroscopy. J. Pharm. Sci. 94 (2005) 209-219