Gallic acid induces apoptosis of lung fibroblasts via a reactive oxygen species-dependent ataxia telangiectasia mutated-p53 activation pathway

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 5, 2010, Pages 2943-2951

  Chuang, Cheng Yen ^a,b   Liu, Hsiang Chun ^b   Wu, Li Chen ^c   Chen, Chiu Yuan ^d   Chang, Jinghua Tsai ^a,e   Hsu, Shih Lan ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL CHI NAN UNIVERSITY   (Taiwan)

^d NANHUA UNIVERSITY   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Ataxia telangiectasia mutated; Gallic acid; Idiopathic pulmonary fibrosis; P53; Reactive oxygen species

Indexed keywords

ATM PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; GALLIC ACID; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CYTOLOGY; DNA DAMAGE; DRUG EFFECT; FLOW CYTOMETRY; LUNG; METABOLISM; MOUSE;

ANIMALS; APOPTOSIS; CELL CYCLE PROTEINS; CELLS, CULTURED; DNA DAMAGE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; GALLIC ACID; LUNG; MICE; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 77949347669     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf9043265     Document Type: Article

References (35)

1. Bjoraker, J. A.; Ryu, J. H.; Edwin, M. K.; Myers, J. L.; Tazelaar, H. D.; Schroeder, D. R.; Offord, K. P. Prognostic significance of histopathologic subsets in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 1998, 157 (1), 199-203.
2. Meltzer, E. B.; Noble, P. W. Idiopathic pulmonary fibrosis. Orphanet J. Rare Dis. 2008, 3, 8.
3. Selman, M.; King, T. E.; Pardo, A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann. Intern. Med. 2001, 134 (2), 136-151.
4. Wynn, T. A. Cellular and molecular mechanisms of fibrosis. J Pathol 2008, 214 (2), 199-210.
5. Hinz, B. Formation and function of the myofibroblast during tissue repair. J. Invest. Dermatol. 2007, 127 (3), 526-537.
6. Uhal, B. D.; Joshi, I.; Hughes, W. F.; Ramos, C.; Pardo, A.; Selman, M. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am. J. Physiol. 1998, 275 (6 Pt 1), L1192-L1199.
7. Gharaee-Kermani, M.; Gyetko, M. R.; Hu, B.; Phan, S. H. New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis: a potential role for stem cells in the lung parenchyma and implications for therapy. Pharm. Res. 2007, 24 (5), 819-841.
8. Sohi, K. K.; Mittal, N.; Hundal, M. K.; Khanduja, K. L. Gallic acid, an antioxidant, exhibits antiapoptotic potential in normal human lymphocytes: A Bcl-2 independent mechanism. J. Nutr. SCi. Vitaminol. (Tokyo) 2003, 49 (4), 221-227.
9. Kim, Y. J. Antimelanogenic and antioxidant properties of gallic acid. Biol. Pharm. Bull. 2007, 30 (6), 1052-1055.
10. Hsu, C. L.; Yen, G. C. Effect of gallic acid on high fat diet-induced dyslipidaemia, hepatosteatosis and oxidative stress in rats. Br. J. Nutr. 2007, 98 (4), 727-735.
11. Nakano, N.; Shirasaka, N.; Koyama, H.; Hino, M.; Murakami, T.; Shimizu, S.; Yoshizumi, H. C19 odd-chain polyunsaturated fatty acids (PUfas) are metabolized to C21-PUfas in a rat liver cell line, and curcumin, gallic acid, and their related compounds inhibit their desaturation. Biosci. Biotechnol. Biochem. 2000, 64 (8), 16411650.
12. Liu, Z.; Schwimer, J.; Liu, D.; Lewis, J.; Greenway, F. L.; York, D. A.; Woltering, E. A. Gallic acid is partially responsible for the antiangiogenic activities of Rubus leaf extract. Phytother. Res. 2006, 20 (9), 806-813.
13. Boyd, I.; Beveridge, E. G. Relationship between the antibacterial activity towards Escherichia coli NCTC 5933 and the physicochemical properties of some esters of 3,4,5-trihydroxybenzoic acid (Gallic acid). Microbios. 1979, 24 (97-98), 173-184.
14. Kim, S. H.; Jun, C. D.; Suk, K.; Choi, B. J.; Lim, H.; Park, S.; Lee, S. H.; Shin, H. Y.; Kim, D. K.; Shin, T. Y. Gallic acid inhibits histamine release and pro-inflammatory cytokine production in mast cells. Toxicol. Sci. 2006, 91 (1), 123-131.
15. Sanae, F.; Miyaichi, Y.; Hayashi, H. Potentiation of vasoconstrictor response and inhibition of endothelium-dependent vasorelaxation by gallic acid in rat aorta. Planta Med. 2002, 68 (8), 690-693.
16. Appeldoorn, C. C.; Bonnefoy, A.; Lutters, B. C.; Daenens, K.; van Berkel, T. J.; Hoylaerts, M. F.; Biessen, E. A. Gallic acid antagonizes P-selectin-mediated platelet-leukocyte interactions: implications for the French paradox. Circulation 2005, 111 (1), 106-112.
17. Ban, J. Y.; Nguyen, H. T.; Lee, H. J.; Cho, S. O.; Ju, H. S.; Kim, J. Y.; Bae, K.; Song, K. S.; Seong, Y. H. Neuroprotective properties of gallic acid from Sanguisorbae radix on amyloid beta protein (25-35)induced toxicity in cultured rat cortical neurons. Biol. Pharm. Bull. 2008, 31(1), 149-153.
18. Jadon, A.; Bhadauria, M.; Shukla, S. Protective effect of Terminalia belerica Roxb. and gallic acid against carbon tetrachloride induced damage in albino rats. J. Ethnopharmacol. 2007, 109 (2), 214-218.
19. Abdelwahed, A.; Bouhlel, I.; Skandrani, I.; Valenti, K.; Kadri, M.; Guiraud, P.; Steiman, R.; Mariotte, A. M.; Ghedira, K.; Laporte, F.; Dijoux-Franca, M. G.; Chekir-Ghedira, L. Study of antimutagenic and antioxidant activities of gallic acid and 1,2,3,4, 6-pentagalloylglucose from Pistacia lentiscus. Confirmation by microarray expression profiling. Chem.-Biol. Interact. 2007, 165 (1), 1-13.
20. Inoue, M.; Suzuki, R.; Sakaguchi, N.; Li, Z.; Takeda, T.; Ogihara, Y.; Jiang, B. Y.; Chen, Y. Selective induction of cell death in cancer cells by gallic acid. Biol. Pharm. Bull. 1995, 18 (11), 1526-1530.
21. Madlener, S.; Illmer, C.; Horvath, Z.; Saiko, P.; Losert, A.; Herbacek, I.; Grusch, M.; Elford, H. L.; Krupitza, G.; Bernhaus, A.; FritzerSzekeres, M.; Szekeres, T. Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells. Cancer Lett. 2007, 245 (1-2), 156-162.
22. Hsu, C. L.; Lo, W. H.; Yen, G. C. Gallic acid induces apoptosis in 3T3-L1 pre-adipocytes via a Fas- and mitochondrial-mediated pathway. J. Agric. Food Chem. 2007, 55 (18), 7359-7365.
23. Inoue, M.; Sakaguchi, N.; Isuzugawa, K.; Tani, H.; Ogihara, Y. Role of reactive oxygen species in gallic acid-induced apoptosis. Biol. Pharm. Bull. 2000, 23 (10), 1153-1157.
24. Azmi, A. S.; Bhat, S. H.; Hanif, S.; Hadi, S. M. Plant polyphenols mobilize endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for anticancer properties. FEBS Lett. 2006, 580 (2), 533-538.
25. Yoshioka, K.; Kataoka, T.; Hayashi, T.; Hasegawa, M.; Ishi, Y.; Hibasami, H. Induction of apoptosis by gallic acid in human stomach cancer KATO III and colon adenocarcinoma COLO 205 cell lines. Oncol. Rep. 2000, 7 (6), 1221-1223.
26. Gomes, C. A.; da Cruz, T. G.; Andrade, J. L.; Milhazes, N.; Borges, F.; Marques, M. P. Anticancer activity of phenolic acids of natural or synthetic origin: a structure-activity study. J. Med. Chem. 2003, 46 (25), 5395-5401.
27. Jacobi, H.; Eicke, B.; Witte, I. DNA strand break induction and enhanced cytotoxicity of propyl gallate in the presence of copper(II). Free Radical Biol. Med. 1998, 24 (6), 972-978.
28. Sakaguchi, N.; Inoue, M.; Ogihara, Y. Reactive oxygen species and intracellular Ca2+, common signals for apoptosis induced by gallic acid. Biochem. Pharmacol. 1998, 55 (12), 1973-1981.
29. Inoue, M.; Suzuki, R.; Koide, T.; Sakaguchi, N.; Ogihara, Y.; Yabu, Y. Antioxidant, gallic acid, induces apoptosis in HL-60RG cells. Biochem. Biophys. Res. Commun. 1994, 204 (2), 898-904.
30. Yoshino, M.; Haneda, M.; Naruse, M.; Htay, H. H.; Iwata, S.; Tsubouchi, R.; Murakami, K. Prooxidant action of gallic acid compounds: copper-dependent strand breaks and the formation of 8-hydroxy-2'-deoxyguanosine in DNA. Toxicol. In Vitro 2002, 16 (6), 705-709.
31. Agarwal, C.; Tyagi, A.; Agarwal, R. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells. Mol. Cancer Ther. 2006, 5 (12), 32943302.
32. Lavin, M. F. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat. Rev. Mol. Cell Biol. 2008, 9 (10), 759-769.
33. Coutts, A. S.; La Thangue, N. The p53 response during DNA damage: impact of transcriptional cofactors. Biochem. Soc. Symp. 2006, 73, 181-189.
34. Yu, J.; Zhang, L.; Hwang, P. M.; Kinzler, K. W.; Vogelstein, B. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol. Cell 2001, 7(3), 673-682.
35. Yu, J.; Wang, Z.; Kinzler, K. W.; Vogelstein, B.; Zhang, L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc. Natl. Acad. Sci. U.S.A. 2003, 100 (4), 1931-1936.