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Volumn 117, Issue 1, 2010, Pages 96-102

The effect of overweight and obesity on proliferation and activation of AKT and ERK in human endometria

Author keywords

AKT; Endometrial cancer; ERK1,2; Obesity; Proliferation

Indexed keywords

ESTROGEN; HISTONE H3; INSULIN; KI 67 ANTIGEN; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; STEROID;

EID: 77949335473     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2009.12.022     Document Type: Article
Times cited : (23)

References (62)
  • 1
    • 0021279023 scopus 로고
    • Serum hormones and their receptors in women with normal and inadequate corpus luteum function
    • McRae M.A., Blasco L., and Lyttle C.R. Serum hormones and their receptors in women with normal and inadequate corpus luteum function. Fertil. Steril. 42 (1984) 58-63
    • (1984) Fertil. Steril. , vol.42 , pp. 58-63
    • McRae, M.A.1    Blasco, L.2    Lyttle, C.R.3
  • 2
    • 9644303358 scopus 로고    scopus 로고
    • Estrogen-induced proliferation of normal endometrial glandular cells is initiated by transcriptional activation of cyclin D1 via binding of c-Jun to an AP-1 sequence
    • Shiozawa T., Miyamoto T., Kashima H., Nakayama K., Nikaido T., and Konishi I. Estrogen-induced proliferation of normal endometrial glandular cells is initiated by transcriptional activation of cyclin D1 via binding of c-Jun to an AP-1 sequence. Oncogene 23 (2004) 8603-8610
    • (2004) Oncogene , vol.23 , pp. 8603-8610
    • Shiozawa, T.1    Miyamoto, T.2    Kashima, H.3    Nakayama, K.4    Nikaido, T.5    Konishi, I.6
  • 3
    • 27744485639 scopus 로고    scopus 로고
    • Cytokines, chemokines and growth factors in endometrium related to implantation
    • Dimitriadis E., White C.A., Jones R.L., and Salamonsen L.A. Cytokines, chemokines and growth factors in endometrium related to implantation. Hum. Reprod. Update 11 (2005) 613-630
    • (2005) Hum. Reprod. Update , vol.11 , pp. 613-630
    • Dimitriadis, E.1    White, C.A.2    Jones, R.L.3    Salamonsen, L.A.4
  • 4
    • 0141740195 scopus 로고    scopus 로고
    • Effects of leptin on the production of cytokines by cultured human endometrial stromal and epithelial cells
    • Fukuda J., Nasu K., Sun B., Shang S., Kawano Y., and Miyakawa I. Effects of leptin on the production of cytokines by cultured human endometrial stromal and epithelial cells. Fertil. Steril. 80 (2003) 783-787
    • (2003) Fertil. Steril. , vol.80 , pp. 783-787
    • Fukuda, J.1    Nasu, K.2    Sun, B.3    Shang, S.4    Kawano, Y.5    Miyakawa, I.6
  • 5
    • 33845592201 scopus 로고    scopus 로고
    • Adipose tissue-derived factors: impact on health and disease
    • Trujillo M.E., and Scherer P.E. Adipose tissue-derived factors: impact on health and disease. Endocr. Rev. 27 (2006) 762-778
    • (2006) Endocr. Rev. , vol.27 , pp. 762-778
    • Trujillo, M.E.1    Scherer, P.E.2
  • 6
    • 0036907571 scopus 로고    scopus 로고
    • Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review
    • Kaaks R., Lukanova A., and Kurzer M.S. Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review. Cancer Epidemiol. Biomarkers Prev. 11 (2002) 1531-1543
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , pp. 1531-1543
    • Kaaks, R.1    Lukanova, A.2    Kurzer, M.S.3
  • 10
    • 1842866813 scopus 로고    scopus 로고
    • Obesity at different ages and endometrial cancer risk factors in urban Shanghai, China
    • Xu W., Dai Q., Ruan Z., Cheng J., Jin F., and Shu X. Obesity at different ages and endometrial cancer risk factors in urban Shanghai, China. Zhonghua Liu Xing Bing Xue Za Zhi 23 (2002) 347-351
    • (2002) Zhonghua Liu Xing Bing Xue Za Zhi , vol.23 , pp. 347-351
    • Xu, W.1    Dai, Q.2    Ruan, Z.3    Cheng, J.4    Jin, F.5    Shu, X.6
  • 11
    • 0034813764 scopus 로고    scopus 로고
    • Role of exogenous and endogenous hormones in endometrial cancer: review of the evidence and research perspectives
    • Akhmedkhanov A., Zeleniuch-Jacquotte A., and Toniolo P. Role of exogenous and endogenous hormones in endometrial cancer: review of the evidence and research perspectives. Ann. N. Y. Acad. Sci. 943 (2001) 296-315
    • (2001) Ann. N. Y. Acad. Sci. , vol.943 , pp. 296-315
    • Akhmedkhanov, A.1    Zeleniuch-Jacquotte, A.2    Toniolo, P.3
  • 14
    • 0036714218 scopus 로고    scopus 로고
    • Overweight, obesity, and cancer risk
    • Bianchini F., Kaaks R., and Vainio H. Overweight, obesity, and cancer risk. Lancet Oncol. 3 (2002) 565-574
    • (2002) Lancet Oncol. , vol.3 , pp. 565-574
    • Bianchini, F.1    Kaaks, R.2    Vainio, H.3
  • 15
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    • Calle E.E., Rodriguez C., Walker-Thurmond K., and Thun M.J. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N. Engl. J. Med. 348 (2003) 1625-1638
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3    Thun, M.J.4
  • 16
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • Hahn W.C., and Weinberg R.A. Rules for making human tumor cells. N. Engl. J. Med. 347 (2002) 1593-1603
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 17
    • 33847240933 scopus 로고    scopus 로고
    • Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium
    • Lax S.F. Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium. Pathology 39 (2007) 46-54
    • (2007) Pathology , vol.39 , pp. 46-54
    • Lax, S.F.1
  • 19
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering B.M., and Coffer P.J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376 (1995) 599-602
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 20
    • 0031913246 scopus 로고    scopus 로고
    • Mechanism of activation and function of protein kinase B
    • Alessi D.R., and Cohen P. Mechanism of activation and function of protein kinase B. Curr. Opin. Genet. Dev. 8 (1998) 55-62
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 55-62
    • Alessi, D.R.1    Cohen, P.2
  • 21
    • 0035970041 scopus 로고    scopus 로고
    • Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction
    • Negoro S., Oh H., Tone E., Kunisada K., Fujio Y., Walsh K., et al. Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction. Circulation 103 (2001) 555-561
    • (2001) Circulation , vol.103 , pp. 555-561
    • Negoro, S.1    Oh, H.2    Tone, E.3    Kunisada, K.4    Fujio, Y.5    Walsh, K.6
  • 22
    • 0036150402 scopus 로고    scopus 로고
    • Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen
    • Ivanova T., Mendez P., Garcia-Segura L.M., and Beyer C. Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen. J. Neuroendocrinol. 14 (2002) 73-79
    • (2002) J. Neuroendocrinol. , vol.14 , pp. 73-79
    • Ivanova, T.1    Mendez, P.2    Garcia-Segura, L.M.3    Beyer, C.4
  • 23
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • Schubbert S., Shannon K., and Bollag G. Hyperactive Ras in developmental disorders and cancer. Nat. Rev. Cancer 7 (2007) 295-308
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 24
    • 4243175922 scopus 로고    scopus 로고
    • In vivo and in vitro regulation of Akt activation in human endometrial cells is estrogen dependent
    • Guzeloglu Kayisli O., Kayisli U.A., Luleci G., and Arici A. In vivo and in vitro regulation of Akt activation in human endometrial cells is estrogen dependent. Biol. Reprod. 71 (2004) 714-721
    • (2004) Biol. Reprod. , vol.71 , pp. 714-721
    • Guzeloglu Kayisli, O.1    Kayisli, U.A.2    Luleci, G.3    Arici, A.4
  • 25
    • 34447334831 scopus 로고    scopus 로고
    • PI3K/Akt and ERK1/2 signalling pathways are involved in endometrial cell migration induced by 17beta-estradiol and growth factors
    • Gentilini D., Busacca M., Di Francesco S., Vignali M., Viganò P., and Di Blasio A.M. PI3K/Akt and ERK1/2 signalling pathways are involved in endometrial cell migration induced by 17beta-estradiol and growth factors. Mol. Hum. Reprod. 13 (2007) 317-322
    • (2007) Mol. Hum. Reprod. , vol.13 , pp. 317-322
    • Gentilini, D.1    Busacca, M.2    Di Francesco, S.3    Vignali, M.4    Viganò, P.5    Di Blasio, A.M.6
  • 26
    • 33745167352 scopus 로고    scopus 로고
    • 17β-Estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells
    • Guo R.X., Wei L.H., Tu Z., Sun P.M., Wang J.L., Zhao D., et al. 17β-Estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells. J. Steroid. Biochem. Mol. Biol. 99 (2006) 9-18
    • (2006) J. Steroid. Biochem. Mol. Biol. , vol.99 , pp. 9-18
    • Guo, R.X.1    Wei, L.H.2    Tu, Z.3    Sun, P.M.4    Wang, J.L.5    Zhao, D.6
  • 27
    • 77949337602 scopus 로고    scopus 로고
    • Membrane-initiated nongenomic effect on mitogen-activated protein kinase signal transduction of estrogen in endometrial carcinoma cell
    • Zhang L.L., Li X.P., Wang J.L., and Wei L.H. Membrane-initiated nongenomic effect on mitogen-activated protein kinase signal transduction of estrogen in endometrial carcinoma cell. Zhonghua Fu Chan Ke Za Zhi 43 (2008) 615-618
    • (2008) Zhonghua Fu Chan Ke Za Zhi , vol.43 , pp. 615-618
    • Zhang, L.L.1    Li, X.P.2    Wang, J.L.3    Wei, L.H.4
  • 28
    • 33745108419 scopus 로고    scopus 로고
    • Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways
    • Sharma D., Saxena N.K., Vertino P.M., and Anania F.A. Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways. Endocr. Relat. Cancer 13 (2006) 629-640
    • (2006) Endocr. Relat. Cancer , vol.13 , pp. 629-640
    • Sharma, D.1    Saxena, N.K.2    Vertino, P.M.3    Anania, F.A.4
  • 29
    • 15944403593 scopus 로고    scopus 로고
    • Dose-dependent insulin regulation of insulin-like growth factor binding protein-1 in human endometrial stromal cells is mediated by distinct signaling pathways
    • Lathi R.B., Hess A.P., Tulac S., Nayak N.R., Conti M., and Giudice L.C. Dose-dependent insulin regulation of insulin-like growth factor binding protein-1 in human endometrial stromal cells is mediated by distinct signaling pathways. J. Clin. Endocrinol. Metab. 90 (2005) 1599-1606
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 1599-1606
    • Lathi, R.B.1    Hess, A.P.2    Tulac, S.3    Nayak, N.R.4    Conti, M.5    Giudice, L.C.6
  • 31
    • 0026663895 scopus 로고
    • Tumour markers in oncology: past, present and future
    • Magdelénat H. Tumour markers in oncology: past, present and future. J. Immunol. Methods 150 (1992) 133-143
    • (1992) J. Immunol. Methods , vol.150 , pp. 133-143
    • Magdelénat, H.1
  • 32
    • 0038746603 scopus 로고    scopus 로고
    • Immunocytochemical assessment of mitotic activity with an antibody to phosphorylated histone H3 in the macaque and human endometrium
    • Brenner R.M., Slayden O.D., Rodgers W.H., Critchley H.O., Carroll R., Nie X.J., et al. Immunocytochemical assessment of mitotic activity with an antibody to phosphorylated histone H3 in the macaque and human endometrium. Hum. Reprod. 18 (2003) 1185-1193
    • (2003) Hum. Reprod. , vol.18 , pp. 1185-1193
    • Brenner, R.M.1    Slayden, O.D.2    Rodgers, W.H.3    Critchley, H.O.4    Carroll, R.5    Nie, X.J.6
  • 34
    • 0021891255 scopus 로고
    • TB Health implications of obesity: an NIH Consensus Development Conference
    • Burton B.T., Foster W.R., Hirsch J., and Van I. TB Health implications of obesity: an NIH Consensus Development Conference. Int. J. Obes. 9 (1985) 155-170
    • (1985) Int. J. Obes. , vol.9 , pp. 155-170
    • Burton, B.T.1    Foster, W.R.2    Hirsch, J.3    Van, I.4
  • 35
    • 55849096599 scopus 로고    scopus 로고
    • MicroRNA signature and regulatory functions in the endometrium during normal and disease states
    • Pan Q., and Chegini N. MicroRNA signature and regulatory functions in the endometrium during normal and disease states. Semin. Reprod. Med. 26 (2008) 479-493
    • (2008) Semin. Reprod. Med. , vol.26 , pp. 479-493
    • Pan, Q.1    Chegini, N.2
  • 36
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
    • Calle E.E., and Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat. Rev. Cancer 4 (2004) 579-591
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 37
    • 0033984235 scopus 로고    scopus 로고
    • The Ki-67 protein: from the known and the unknown
    • Scholzen T., and Gerdes J. The Ki-67 protein: from the known and the unknown. J. Cell Physiol. 182 (2000) 311-322
    • (2000) J. Cell Physiol. , vol.182 , pp. 311-322
    • Scholzen, T.1    Gerdes, J.2
  • 38
    • 0036153461 scopus 로고    scopus 로고
    • Ki67 protein: the immaculate deception?
    • Brown D.C., and Gatter K.C. Ki67 protein: the immaculate deception?. Histopathology 40 (2002) 2-11
    • (2002) Histopathology , vol.40 , pp. 2-11
    • Brown, D.C.1    Gatter, K.C.2
  • 39
    • 0030447934 scopus 로고    scopus 로고
    • Proliferative activity of the endometrium throughout the menstrual cycle in infertile women with and without endometriosis
    • Jürgensen A., Mettler L., Volkov N.I., and Parwaresch R. Proliferative activity of the endometrium throughout the menstrual cycle in infertile women with and without endometriosis. Fertil. Steril. 66 (1996) 369-375
    • (1996) Fertil. Steril. , vol.66 , pp. 369-375
    • Jürgensen, A.1    Mettler, L.2    Volkov, N.I.3    Parwaresch, R.4
  • 40
    • 0025219285 scopus 로고
    • Review: assessment of cell proliferation in histological material
    • Hall P.A., and Levison D.A. Review: assessment of cell proliferation in histological material. J. Clin. Pathol. 43 (1990) 184-192
    • (1990) J. Clin. Pathol. , vol.43 , pp. 184-192
    • Hall, P.A.1    Levison, D.A.2
  • 42
    • 0031877301 scopus 로고    scopus 로고
    • c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry
    • Prall O.W., Rogan E.M., Musgrove E.A., Watts C.K., and Sutherland R.L. c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry. Mol. Cell Biol. 18 (1998) 4499-4508
    • (1998) Mol. Cell Biol. , vol.18 , pp. 4499-4508
    • Prall, O.W.1    Rogan, E.M.2    Musgrove, E.A.3    Watts, C.K.4    Sutherland, R.L.5
  • 43
    • 0036025267 scopus 로고    scopus 로고
    • The expression of apoptosis-related proteins Bcl-2 and Ki67 in endometrium of ovulatory menstrual cycles
    • Mertens H.J., Heineman M.J., and Evers J.L. The expression of apoptosis-related proteins Bcl-2 and Ki67 in endometrium of ovulatory menstrual cycles. Gynecol. Obstet. Invest 53 (2002) 224-230
    • (2002) Gynecol. Obstet. Invest , vol.53 , pp. 224-230
    • Mertens, H.J.1    Heineman, M.J.2    Evers, J.L.3
  • 44
    • 0036786293 scopus 로고    scopus 로고
    • Apoptosis and apoptosis-related factors Bcl-2, Bax, tumor necrosis factor-alpha, and NF-kappaB in human endometrial hyperplasia and carcinoma
    • Vaskivuo T.E., Stenback F., and Tapanainen J.S. Apoptosis and apoptosis-related factors Bcl-2, Bax, tumor necrosis factor-alpha, and NF-kappaB in human endometrial hyperplasia and carcinoma. Cancer 95 (2002) 1463-1471
    • (2002) Cancer , vol.95 , pp. 1463-1471
    • Vaskivuo, T.E.1    Stenback, F.2    Tapanainen, J.S.3
  • 46
  • 47
    • 0038274803 scopus 로고    scopus 로고
    • Loss of PTEN expression followed by Akt phosphorylation is a poor prognostic factor for patients with endometrial cancer
    • Terakawa N., Kanamori Y., and Yoshida S. Loss of PTEN expression followed by Akt phosphorylation is a poor prognostic factor for patients with endometrial cancer. Endocr. Relat. Cancer 10 (2003) 203-208
    • (2003) Endocr. Relat. Cancer , vol.10 , pp. 203-208
    • Terakawa, N.1    Kanamori, Y.2    Yoshida, S.3
  • 48
    • 0034906660 scopus 로고    scopus 로고
    • Correlation between loss of PTEN expression and Akt phosphorylation in endometrial carcinoma
    • Kanamori Y., Kigawa J., Itamochi H., Shimada M., Takahashi M., Kamazawa S., et al. Correlation between loss of PTEN expression and Akt phosphorylation in endometrial carcinoma. Clin. Cancer Res. 7 (2001) 892-895
    • (2001) Clin. Cancer Res. , vol.7 , pp. 892-895
    • Kanamori, Y.1    Kigawa, J.2    Itamochi, H.3    Shimada, M.4    Takahashi, M.5    Kamazawa, S.6
  • 49
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: downstream AKTion blocks apoptosis
    • Franke T., Kaplan D., and Cantley L. PI3K: downstream AKTion blocks apoptosis. Cell 88 (1997) 435-437
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.1    Kaplan, D.2    Cantley, L.3
  • 51
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., and Hu L.S. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 (1999) 857-868
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3    Lin, M.Z.4    Juo, P.5    Hu, L.S.6
  • 52
    • 0034486885 scopus 로고    scopus 로고
    • Leptin and leptin receptor are expressed in the human endometrium and endometrial leptin secretion is regulated by the human blastocyst
    • González R.R., Caballero-Campo P., Jasper M., Mercader A., Devoto L., Pellicer A., et al. Leptin and leptin receptor are expressed in the human endometrium and endometrial leptin secretion is regulated by the human blastocyst. J. Clin. Endocrinol. Metab. 85 (2000) 4883-4888
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 4883-4888
    • González, R.R.1    Caballero-Campo, P.2    Jasper, M.3    Mercader, A.4    Devoto, L.5    Pellicer, A.6
  • 55
    • 0026355714 scopus 로고
    • Specific binding sites for insulin and insulin-like growth factor I in human endometrial cancer
    • Nagamani M., Stuart C.A., Dunhardt P.A., and Doherty M.G. Specific binding sites for insulin and insulin-like growth factor I in human endometrial cancer. Am. J. Obstet. Gynecol. 165 (1991) 1865-1871
    • (1991) Am. J. Obstet. Gynecol. , vol.165 , pp. 1865-1871
    • Nagamani, M.1    Stuart, C.A.2    Dunhardt, P.A.3    Doherty, M.G.4
  • 56
    • 0027530865 scopus 로고
    • Tyrosine kinase activity of insulin-like growth factor I and insulin receptors in human endometrium during the menstrual cycle: cyclic variation of insulin receptor expression
    • Strowitzki T., von Eye H.C., Kellerer M., and Häring H.U. Tyrosine kinase activity of insulin-like growth factor I and insulin receptors in human endometrium during the menstrual cycle: cyclic variation of insulin receptor expression. Fertil. Steril. 59 (1993) 315-322
    • (1993) Fertil. Steril. , vol.59 , pp. 315-322
    • Strowitzki, T.1    von Eye, H.C.2    Kellerer, M.3    Häring, H.U.4
  • 58
    • 0034474076 scopus 로고    scopus 로고
    • Sex steroid hormones, sex hormone-binding globulin, and obesity in men and women
    • Tchernof A., and Després J.P. Sex steroid hormones, sex hormone-binding globulin, and obesity in men and women. Horm. Metab. Res. 32 (2000) 526-536
    • (2000) Horm. Metab. Res. , vol.32 , pp. 526-536
    • Tchernof, A.1    Després, J.P.2
  • 61
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T., Hafezi-Moghadam A., Brazil D.P., Ley K., Chin W.W., and Liao J.K. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407 (2000) 538-541
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6


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