Tissue distribution, metabolism and excretion of PGE1 following prolonged high-dose inhalation in neonatal pigs

International Journal of Pharmacology

Volumn 6, Issue 3, 2010, Pages 224-230

  Sood, Beena G ^a   Chen, X ^a   Dawe, E J ^a   Malian, M ^b   Maddipati, K R ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

Author keywords

Aerosolized; Neonatal hypoxemic respiratory failure; Newborn; Persistent pulmonary hypertension of the newborn; Prostaglandin E 1 alprostadil; Selective pulmonary vasodilator

Indexed keywords

15 KETO PROSTAGLANDIN E1; DRUG METABOLITE; PROSTAGLANDIN E1; PROSTAGLANDIN E1 DERIVATIVE; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG MEGADOSE; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LONG TERM EXPOSURE; MASS SPECTROMETRY; MORTALITY; NEBULIZATION; NEBULIZER; NEWBORN; NONHUMAN; OUTCOME ASSESSMENT; SWINE; TISSUE DISTRIBUTION;

EID: 77949295555     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2010.224.230     Document Type: Article

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