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Volumn 117, Issue 1, 2010, Pages 103-108

Activation of mTOR signaling pathway contributes to survival of cervical cancer cells

Author keywords

Cervical cancer; mTOR; P70S6K; Rapamycin; siRNA

Indexed keywords

CISPLATIN; DNA; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; SMALL INTERFERING RNA;

EID: 77949281423     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2009.12.020     Document Type: Article
Times cited : (70)

References (13)
  • 1
    • 37349078725 scopus 로고    scopus 로고
    • Human papillomavirus infection and the development of cervical cancer and related genital neoplasias
    • Paavonen J. Human papillomavirus infection and the development of cervical cancer and related genital neoplasias. Int. J. Infect. Dis. 11 Suppl 2 (2007) S3-S9
    • (2007) Int. J. Infect. Dis. , vol.11 , Issue.SUPPL. 2
    • Paavonen, J.1
  • 2
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • Hay N., and Sonenberg N. Upstream and downstream of mTOR. Genes Dev. 18 (2004) 1926-1945
    • (2004) Genes Dev. , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 3
    • 33746637660 scopus 로고    scopus 로고
    • Current development of mTOR inhibitors as anticancer agents
    • Faivre S., Kroemer G., and Raymond E. Current development of mTOR inhibitors as anticancer agents. Nat. Rev. Drug. Discov. 5 (2006) 671-688
    • (2006) Nat. Rev. Drug. Discov. , vol.5 , pp. 671-688
    • Faivre, S.1    Kroemer, G.2    Raymond, E.3
  • 4
    • 68949198785 scopus 로고    scopus 로고
    • mTOR Signaling Pathway Is a Target for the Treatment of Colorectal Cancer
    • Zhang Y.J., Dai Q., Sun D.F., et al. mTOR Signaling Pathway Is a Target for the Treatment of Colorectal Cancer. Ann. Surg. Oncol. 16 (2009) 2617-2628
    • (2009) Ann. Surg. Oncol. , vol.16 , pp. 2617-2628
    • Zhang, Y.J.1    Dai, Q.2    Sun, D.F.3
  • 5
    • 63149143885 scopus 로고    scopus 로고
    • AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001
    • Marinov M., Ziogas A., Pardo O.E., et al. AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001. Clin. Cancer Res. 15 (2009) 1277-1287
    • (2009) Clin. Cancer Res. , vol.15 , pp. 1277-1287
    • Marinov, M.1    Ziogas, A.2    Pardo, O.E.3
  • 6
    • 34347331090 scopus 로고    scopus 로고
    • An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR
    • Hou G., Xue L., Lu Z., Fan T., Tian F., and Xue Y. An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR. Cancer Lett. 253 (2007) 236-248
    • (2007) Cancer Lett. , vol.253 , pp. 236-248
    • Hou, G.1    Xue, L.2    Lu, Z.3    Fan, T.4    Tian, F.5    Xue, Y.6
  • 7
    • 2942735384 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer
    • Raymond E., Alexandre J., Faivre S., et al. Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer. J. Clin. Oncol. 22 (2004) 2336-2347
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2336-2347
    • Raymond, E.1    Alexandre, J.2    Faivre, S.3
  • 8
    • 51449096670 scopus 로고    scopus 로고
    • A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies
    • Rizzieri D.A., Feldman E., Dipersio J.F., et al. A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies. Clin. Cancer Res. 14 (2008) 2756-2762
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2756-2762
    • Rizzieri, D.A.1    Feldman, E.2    Dipersio, J.F.3
  • 9
    • 66649133114 scopus 로고    scopus 로고
    • A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer
    • Amato R.J., Jac J., Giessinger S., Saxena S., and Willis J.P. A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer. Cancer 115 (2009) 2438-2446
    • (2009) Cancer , vol.115 , pp. 2438-2446
    • Amato, R.J.1    Jac, J.2    Giessinger, S.3    Saxena, S.4    Willis, J.P.5
  • 10
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • Shaw R.J., and Cantley L.C. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441 (2006) 424-430
    • (2006) Nature , vol.441 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 11
    • 0035253411 scopus 로고    scopus 로고
    • Cell-cycle-dependent translational control
    • Pyronnet S., and Sonenberg N. Cell-cycle-dependent translational control. Curr. Opin. Genet. Dev. 11 (2001) 13-18
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 13-18
    • Pyronnet, S.1    Sonenberg, N.2
  • 12
    • 0035859956 scopus 로고    scopus 로고
    • p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
    • Harada H., Andersen J.S., Mann M., Terada N., and Korsmeyer S.J. p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 9666-9670
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 9666-9670
    • Harada, H.1    Andersen, J.S.2    Mann, M.3    Terada, N.4    Korsmeyer, S.J.5
  • 13
    • 12344279947 scopus 로고    scopus 로고
    • TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation
    • Findlay G.M., Harrington L.S., and Lamb R.F. TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation. Curr. Opin. Genet. Dev. 15 (2005) 69-76
    • (2005) Curr. Opin. Genet. Dev. , vol.15 , pp. 69-76
    • Findlay, G.M.1    Harrington, L.S.2    Lamb, R.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.