-
1
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 2002;346:92-98.
-
(2002)
N Engl J Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
-
2
-
-
0032547380
-
Progress in understanding the molecular pathogenesis of human lung cancer
-
Sekido Y, Fong KM, Minna JD. Progress in understanding the molecular pathogenesis of human lung cancer. Biochim Biophys Acta. 1998;1378:F21-F59.
-
(1998)
Biochim Biophys Acta
, vol.1378
-
-
Sekido, Y.1
Fong, K.M.2
Minna, J.D.3
-
3
-
-
0031841384
-
IARC database of p53 gene mutations in human tumors and cell lines: Updated compilation, revised formats and new visualisation tools
-
Hainaut P, Hernandez T, Robinson A, et al. IARC database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools. Nucleic Acids Res. 1998;26:205-213.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 205-213
-
-
Hainaut, P.1
Hernandez, T.2
Robinson, A.3
-
4
-
-
0032803467
-
Meta-analyses of p53 tumor suppressor gene alterations and clinicopathological features in resected lung cancers
-
Tammemagi MC, McLaughlin JR, Bull SB. Meta-analyses of p53 tumor suppressor gene alterations and clinicopathological features in resected lung cancers. Cancer Epidemiol Biomarkers Prev. 1999;8:625-634.
-
(1999)
Cancer Epidemiol Biomarkers Prev
, vol.8
, pp. 625-634
-
-
Tammemagi, M.C.1
McLaughlin, J.R.2
Bull, S.B.3
-
5
-
-
0033765491
-
Prognostic significance of p53 alterations in patients with non-small cell lung cancer: A meta-analysis
-
Mitsudomi T, Hamajima N, Ogawa M, Takahashi T. Prognostic significance of p53 alterations in patients with non-small cell lung cancer: a meta-analysis. Clin Cancer Res. 2000;6:4055-4063.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4055-4063
-
-
Mitsudomi, T.1
Hamajima, N.2
Ogawa, M.3
Takahashi, T.4
-
7
-
-
0032148385
-
The human p19ARF protein encoded by the beta transcript of the p16INK4a is frequently lost in small cell lung cancer
-
Gazzeri S, Della Valle V, Chaussade L, Brambilla C, Larsen CJ, Brambilla E. The human p19ARF protein encoded by the beta transcript of the p16INK4a is frequently lost in small cell lung cancer. Cancer Res. 1998;58:3926-3931.
-
(1998)
Cancer Res
, vol.58
, pp. 3926-3931
-
-
Gazzeri, S.1
Della Valle, V.2
Chaussade, L.3
Brambilla, C.4
Larsen, C.J.5
Brambilla, E.6
-
8
-
-
0032569736
-
Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression
-
Vonlanthen S, Heighway J, Tschan MP, et al. Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression. Oncogene. 1998;17:2779-2785.
-
(1998)
Oncogene
, vol.17
, pp. 2779-2785
-
-
Vonlanthen, S.1
Heighway, J.2
Tschan, M.P.3
-
9
-
-
0030932632
-
MDM2 gene amplification and expression in non-small-cell lung cancer: Immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation
-
Higashiyama M, Doi O, Kodama K, et al. MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation. Br J Cancer. 1997;75:1302-1308.
-
(1997)
Br J Cancer
, vol.75
, pp. 1302-1308
-
-
Higashiyama, M.1
Doi, O.2
Kodama, K.3
-
10
-
-
14444269227
-
Effects of p53 mutants derived from lung carcinomas on the p53-responsive element (p53RE) of the MDM2 gene
-
Gorgoulis VG, Zacharatos PV, Manolis E, et al. Effects of p53 mutants derived from lung carcinomas on the p53-responsive element (p53RE) of the MDM2 gene. Br J Cancer. 1998;77:374-384.
-
(1998)
Br J Cancer
, vol.77
, pp. 374-384
-
-
Gorgoulis, V.G.1
Zacharatos, P.V.2
Manolis, E.3
-
11
-
-
0037129342
-
ARF inactivation are two mutually exclusive events in primary human lung tumors
-
ARF inactivation are two mutually exclusive events in primary human lung tumors. Oncogene. 2002; 21:2750-2761.
-
(2002)
Oncogene
, vol.21
, pp. 2750-2761
-
-
Eymin, B.1
Gazzeri, S.2
Brambilla, C.3
Brambilla, E.4
-
12
-
-
0036710512
-
The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network
-
Mayo LD, Donner DB. The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network. Trends Biochem Sci. 2002;27:462-467.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 462-467
-
-
Mayo, L.D.1
Donner, D.B.2
-
13
-
-
7844247587
-
Mutation analysis of the PTEN/MMAC1 gene in lung cancer
-
Forgacs E, Biesterveld EJ, Sekido Y, et al. Mutation analysis of the PTEN/MMAC1 gene in lung cancer. Oncogene. 1998;17:1557-1565.
-
(1998)
Oncogene
, vol.17
, pp. 1557-1565
-
-
Forgacs, E.1
Biesterveld, E.J.2
Sekido, Y.3
-
14
-
-
0032581519
-
PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers
-
Yokomizo A, Tindall DJ, Drabkin H, et al. PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers. Oncogene. 1998;17:475-479.
-
(1998)
Oncogene
, vol.17
, pp. 475-479
-
-
Yokomizo, A.1
Tindall, D.J.2
Drabkin, H.3
-
15
-
-
0033971901
-
Bcl-2 family: Life-or-death switch
-
Tsujimoto Y, Shimizu S. Bcl-2 family: life-or-death switch. FEBS Lett. 2000;466:6-10.
-
(2000)
FEBS Lett
, vol.466
, pp. 6-10
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
16
-
-
0029826614
-
Apoptosis-related factors p53, Bcl2, and Bax in neuroendocrine lung tumors
-
Brambilla E, Negoescu A, Gazzeri S, et al. Apoptosis-related factors p53, Bcl2, and Bax in neuroendocrine lung tumors. Am J Pathol. 1996;149:1941-1952.
-
(1996)
Am J Pathol
, vol.149
, pp. 1941-1952
-
-
Brambilla, E.1
Negoescu, A.2
Gazzeri, S.3
-
17
-
-
0031964567
-
Bcl-2 immunohistochemistry in a surgical series of non-small cell lung cancer patients
-
Fleming MV, Guinee DG Jr., Chu WS, et al. Bcl-2 immunohistochemistry in a surgical series of non-small cell lung cancer patients. Hum Pathol. 1998;29:60-64.
-
(1998)
Hum Pathol
, vol.29
, pp. 60-64
-
-
Fleming, M.V.1
Guinee Jr., D.G.2
Chu, W.S.3
-
18
-
-
0033031921
-
Expression of apoptosis regulatory proteins of the Bcl-2 family and p53 in primary resected non-small-cell lung cancer
-
Borner MM, Brousset P, Pfanner-Meyer B, et al. Expression of apoptosis regulatory proteins of the Bcl-2 family and p53 in primary resected non-small-cell lung cancer. Br J Cancer. 1999;79:952-958.
-
(1999)
Br J Cancer
, vol.79
, pp. 952-958
-
-
Borner, M.M.1
Brousset, P.2
Pfanner-Meyer, B.3
-
19
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li M, Chen D, Shiloh A, et al. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature. 2002;416:648-653.
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
-
20
-
-
17944379798
-
ASPP proteins specifically stimulate the apoptotic function of p53
-
Samuels-Lev Y, O'Connor DJ, Bergamaschi D, et al. ASPP proteins specifically stimulate the apoptotic function of p53. Mol Cell. 2001;8:781-794.
-
(2001)
Mol Cell
, vol.8
, pp. 781-794
-
-
Samuels-Lev, Y.1
O'Connor, D.J.2
Bergamaschi, D.3
-
22
-
-
0003425741
-
-
Berlin: Springer-Verlag
-
Travis WD, Colby TV, Corrin B, Shimosato Y, Brambilla E. Histological typing of lung and pleural tumours. 3rd edition. Berlin: Springer-Verlag, 1999.
-
(1999)
Histological Typing of Lung and Pleural Tumours. 3rd Edition
-
-
Travis, W.D.1
Colby, T.V.2
Corrin, B.3
Shimosato, Y.4
Brambilla, E.5
-
23
-
-
17944377840
-
Genetic alteration of the β-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion
-
Shigemitsu K, Sekido Y, Usami N, et al. Genetic alteration of the β-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion. Oncogene. 2001;20:4249-4257.
-
(2001)
Oncogene
, vol.20
, pp. 4249-4257
-
-
Shigemitsu, K.1
Sekido, Y.2
Usami, N.3
-
24
-
-
0025765399
-
Preferential expression of c-kit protooncogene transcripts in small cell lung cancer
-
Sekido Y, Obata Y, Ueda R, et al. Preferential expression of c-kit protooncogene transcripts in small cell lung cancer. Cancer Res. 1991;51:2416-2419.
-
(1991)
Cancer Res
, vol.51
, pp. 2416-2419
-
-
Sekido, Y.1
Obata, Y.2
Ueda, R.3
-
25
-
-
0036697802
-
Establishment of a large cell lung cancer cell line (Y-ML-1B) producing granulocyte colony-stimulating factor
-
Sekido Y, Sato M, Usami N, et al. Establishment of a large cell lung cancer cell line (Y-ML-1B) producing granulocyte colony-stimulating factor. Cancer Genet Cytogenet. 2002;137:33-42.
-
(2002)
Cancer Genet Cytogenet
, vol.137
, pp. 33-42
-
-
Sekido, Y.1
Sato, M.2
Usami, N.3
-
26
-
-
0030940210
-
Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer
-
Apolinario RM, van der Valk P, de Jong JS, et al. Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer. J Clin Oncol. 1997;15:2456-2466.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2456-2466
-
-
Apolinario, R.M.1
Van Der Valk, P.2
De Jong, J.S.3
-
27
-
-
0022504347
-
Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors
-
McCarty KS Jr., Szabo E, Flowers JL, et al. Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors. Cancer Res. 1986;46:4244s-4248s.
-
(1986)
Cancer Res
, vol.46
-
-
McCarty Jr., K.S.1
Szabo, E.2
Flowers, J.L.3
-
30
-
-
0029857892
-
DNA sequence analysis of exons 2 through 11 and immunohistochemical staining are required to detect all known p53 alterations in human malignancies
-
Casey G, Lopez ME, Ramos JC, et al. DNA sequence analysis of exons 2 through 11 and immunohistochemical staining are required to detect all known p53 alterations in human malignancies. Oncogene. 1996;13:1971-1981.
-
(1996)
Oncogene
, vol.13
, pp. 1971-1981
-
-
Casey, G.1
Lopez, M.E.2
Ramos, J.C.3
-
31
-
-
0033227089
-
Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes
-
Fujita T, Kiyama M, Tomizawa Y, Kohno T, Yokota J. Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes. Int J Oncol. 1999;15:927-934.
-
(1999)
Int J Oncol
, vol.15
, pp. 927-934
-
-
Fujita, T.1
Kiyama, M.2
Tomizawa, Y.3
Kohno, T.4
Yokota, J.5
-
32
-
-
0033595018
-
Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array
-
Ahrendt SA, Halachmi S, Chow JT, et al. Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array. Proc Natl Acad Sci USA. 1999;96:7382-7387.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7382-7387
-
-
Ahrendt, S.A.1
Halachmi, S.2
Chow, J.T.3
-
33
-
-
0037311184
-
Pathogenetic and biologic significance of TP14ARF alterations in nonsmall cell lung carcinoma
-
Park MJ, Shimizu K, Nakano T, et al. Pathogenetic and biologic significance of TP14ARF alterations in nonsmall cell lung carcinoma. Cancer Genet Cytogenet. 2003;141:5-13.
-
(2003)
Cancer Genet Cytogenet
, vol.141
, pp. 5-13
-
-
Park, M.J.1
Shimizu, K.2
Nakano, T.3
-
34
-
-
0029891010
-
Immunohistochemical and molecular evaluation of the mdm-2 gene product in bronchogenic carcinoma
-
Gorgoulis VG, Rassidakis GZ, Karameris AM, et al. Immunohistochemical and molecular evaluation of the mdm-2 gene product in bronchogenic carcinoma. Mod Pathol. 1996;9:544-554.
-
(1996)
Mod Pathol
, vol.9
, pp. 544-554
-
-
Gorgoulis, V.G.1
Rassidakis, G.Z.2
Karameris, A.M.3
-
35
-
-
0033536063
-
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
-
Tao W, Levine AJ. P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Proc Natl Acad Sci USA. 1999;96:6937-6941.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6937-6941
-
-
Tao, W.1
Levine, A.J.2
-
36
-
-
0035949588
-
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
-
Mayo LD, Donner DB. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc Natl Acad Sci USA. 2001;98:11598-11603.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11598-11603
-
-
Mayo, L.D.1
Donner, D.B.2
-
37
-
-
0036094196
-
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation
-
Soria JC, Lee HY, Lee JI, et al. Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. Clin Cancer Res. 2002;8:1178-1184.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1178-1184
-
-
Soria, J.C.1
Lee, H.Y.2
Lee, J.I.3
-
38
-
-
0035872199
-
Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
-
Brognard J, Clark AS, Ni Y, Dennis PA. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res. 2001;61:3986-3997.
-
(2001)
Cancer Res
, vol.61
, pp. 3986-3997
-
-
Brognard, J.1
Clark, A.S.2
Ni, Y.3
Dennis, P.A.4
|