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Volumn 125, Issue SUPPL. 1, 2010, Pages

Future directions in hemostasis: Normalizing the lives of patients with hemophilia

Author keywords

Drug delivery systems; Engineered altered activity clotting factors; Prolonged half life proteins; Recombinant clotting factors; Targeting of activated platelets

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; BLOOD CLOTTING FACTOR; GLUTAMIC ACID; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 9;

EID: 77949267125     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.01.044     Document Type: Review
Times cited : (13)

References (38)
  • 1
    • 0035822038 scopus 로고    scopus 로고
    • The hemophilias-from royal genes to gene therapy
    • Mannucci P.M., and Tuddenham E.G. The hemophilias-from royal genes to gene therapy. N Engl J Med 344 (2001) 1773-1779
    • (2001) N Engl J Med , vol.344 , pp. 1773-1779
    • Mannucci, P.M.1    Tuddenham, E.G.2
  • 2
    • 63149161694 scopus 로고    scopus 로고
    • Gene therapy for hemophilia: clinical trials and technical tribulations
    • Viiala N.O., Larsen S.R., and Rasko J.E. Gene therapy for hemophilia: clinical trials and technical tribulations. Semin Thromb Hemost 35 (2009) 81-92
    • (2009) Semin Thromb Hemost , vol.35 , pp. 81-92
    • Viiala, N.O.1    Larsen, S.R.2    Rasko, J.E.3
  • 6
    • 33646147385 scopus 로고    scopus 로고
    • Strategies towards a longer acting factor VIII
    • Saenko E.L., and Pipe S.W. Strategies towards a longer acting factor VIII. Haemophilia 12 Suppl 3 (2006) 42-51
    • (2006) Haemophilia , vol.12 , Issue.SUPPL. 3 , pp. 42-51
    • Saenko, E.L.1    Pipe, S.W.2
  • 7
    • 33749121585 scopus 로고    scopus 로고
    • Pharmacokinetic consequences of pegylation
    • Hamidi M., Azadi A., and Rafiei P. Pharmacokinetic consequences of pegylation. Drug Deliv 13 (2006) 399-409
    • (2006) Drug Deliv , vol.13 , pp. 399-409
    • Hamidi, M.1    Azadi, A.2    Rafiei, P.3
  • 8
    • 33748689917 scopus 로고    scopus 로고
    • GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli
    • DeFrees S., Wang Z.G., Xing R., Scott A.E., Wang J., Zopf D., et al. GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli. Glycobiology 16 (2006) 833-843
    • (2006) Glycobiology , vol.16 , pp. 833-843
    • DeFrees, S.1    Wang, Z.G.2    Xing, R.3    Scott, A.E.4    Wang, J.5    Zopf, D.6
  • 9
    • 70449461639 scopus 로고    scopus 로고
    • Genetic fusion to albumin improves the pharmacokinetic properties of factor IX
    • Metzner H.J., Weimer T., Kronthaler U., Lang W., and Schulte S. Genetic fusion to albumin improves the pharmacokinetic properties of factor IX. Thromb Haemost 102 (2009) 634-644
    • (2009) Thromb Haemost , vol.102 , pp. 634-644
    • Metzner, H.J.1    Weimer, T.2    Kronthaler, U.3    Lang, W.4    Schulte, S.5
  • 10
    • 33744937065 scopus 로고    scopus 로고
    • Monomeric Fc fusions: impact on pharmacokinetic and biological activity of protein therapeutics
    • Dumont J.A., Low S.C., Peters R.T., and Bitonti A.J. Monomeric Fc fusions: impact on pharmacokinetic and biological activity of protein therapeutics. BioDrugs 20 (2006) 151-160
    • (2006) BioDrugs , vol.20 , pp. 151-160
    • Dumont, J.A.1    Low, S.C.2    Peters, R.T.3    Bitonti, A.J.4
  • 11
    • 38349083504 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A
    • Powell J.S., Nugent D.J., Harrison J.A., Soni A., Luk A., Stass H., et al. Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A. J Thromb Haemost 6 (2008) 277-283
    • (2008) J Thromb Haemost , vol.6 , pp. 277-283
    • Powell, J.S.1    Nugent, D.J.2    Harrison, J.A.3    Soni, A.4    Luk, A.5    Stass, H.6
  • 12
    • 33845241302 scopus 로고    scopus 로고
    • Prolonged bleeding-free period following prophylactic infusion of recombinant factor VIII reconstituted with pegylated liposomes
    • Spira J., Plyushch O.P., Andreeva T.A., and Andreev Y. Prolonged bleeding-free period following prophylactic infusion of recombinant factor VIII reconstituted with pegylated liposomes. Blood 108 (2006) 3668-3673
    • (2006) Blood , vol.108 , pp. 3668-3673
    • Spira, J.1    Plyushch, O.P.2    Andreeva, T.A.3    Andreev, Y.4
  • 13
    • 0034490003 scopus 로고    scopus 로고
    • Polysialic acids: potential in improving the stability and pharmacokinetics of proteins and other therapeutics
    • Gregoriadis G., Fernandes A., Mital M., and McCormack B. Polysialic acids: potential in improving the stability and pharmacokinetics of proteins and other therapeutics. Cell Mol Life Sci 57 (2000) 1964-1969
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1964-1969
    • Gregoriadis, G.1    Fernandes, A.2    Mital, M.3    McCormack, B.4
  • 14
    • 0036256925 scopus 로고    scopus 로고
    • Pharmacokinetics of recombinant factor IX after intravenous and subcutaneous administration in dogs and cynomolgus monkeys
    • McCarthy K., Stewart P., Sigman J., Read M., Keith Jr. J.C., Brinkhous K.M., et al. Pharmacokinetics of recombinant factor IX after intravenous and subcutaneous administration in dogs and cynomolgus monkeys. Thromb Haemost 87 (2002) 824-830
    • (2002) Thromb Haemost , vol.87 , pp. 824-830
    • McCarthy, K.1    Stewart, P.2    Sigman, J.3    Read, M.4    Keith Jr., J.C.5    Brinkhous, K.M.6
  • 15
    • 10744223774 scopus 로고    scopus 로고
    • Reduced bleeding events with subcutaneous administration of recombinant human factor IX in immune-tolerant hemophilia B dogs
    • Russell K.E., Olsen E.H., Raymer R.A., Merricks E.P., Bellinger D.A., Read M.S., et al. Reduced bleeding events with subcutaneous administration of recombinant human factor IX in immune-tolerant hemophilia B dogs. Blood 102 (2003) 4393-4398
    • (2003) Blood , vol.102 , pp. 4393-4398
    • Russell, K.E.1    Olsen, E.H.2    Raymer, R.A.3    Merricks, E.P.4    Bellinger, D.A.5    Read, M.S.6
  • 16
    • 37149029665 scopus 로고    scopus 로고
    • Inhibitors in haemophilia A: current management and open issues
    • Haya S., Moret A., Cid A.R., Cortina V., Casana P., Cabrera N., et al. Inhibitors in haemophilia A: current management and open issues. Haemophilia 13 Suppl 5 (2007) 52-60
    • (2007) Haemophilia , vol.13 , Issue.SUPPL. 5 , pp. 52-60
    • Haya, S.1    Moret, A.2    Cid, A.R.3    Cortina, V.4    Casana, P.5    Cabrera, N.6
  • 17
    • 0025180213 scopus 로고
    • Efficacy and safety of vapor-heated anti-inhibitor coagulant complex in hemophilia patients. FEIBA Study Group
    • Hilgartner M., Aledort L., Andes A., and Gill J. Efficacy and safety of vapor-heated anti-inhibitor coagulant complex in hemophilia patients. FEIBA Study Group. Transfusion 30 (1990) 626-630
    • (1990) Transfusion , vol.30 , pp. 626-630
    • Hilgartner, M.1    Aledort, L.2    Andes, A.3    Gill, J.4
  • 18
    • 34248562674 scopus 로고    scopus 로고
    • Prophylactic treatment with activated prothrombin complex concentrate (FEIBA) reduces the frequency of bleeding episodes in paediatric patients with haemophilia A and inhibitors
    • Leissinger C.A., Becton D.L., Ewing N.P., and Valentino L.A. Prophylactic treatment with activated prothrombin complex concentrate (FEIBA) reduces the frequency of bleeding episodes in paediatric patients with haemophilia A and inhibitors. Haemophilia 13 (2007) 249-255
    • (2007) Haemophilia , vol.13 , pp. 249-255
    • Leissinger, C.A.1    Becton, D.L.2    Ewing, N.P.3    Valentino, L.A.4
  • 19
    • 0030837755 scopus 로고    scopus 로고
    • Multicenter retrospective study on the utilization of FEIBA in France in patients with factor VIII and factor IX inhibitors. French FEIBA Study Group. Factor Eight Bypassing Activity
    • Negrier C., Goudemand J., Sultan Y., Bertrand M., Rothschild C., and Lauroua P. Multicenter retrospective study on the utilization of FEIBA in France in patients with factor VIII and factor IX inhibitors. French FEIBA Study Group. Factor Eight Bypassing Activity. Thromb Haemost 77 (1997) 1113-1119
    • (1997) Thromb Haemost , vol.77 , pp. 1113-1119
    • Negrier, C.1    Goudemand, J.2    Sultan, Y.3    Bertrand, M.4    Rothschild, C.5    Lauroua, P.6
  • 20
    • 27744439015 scopus 로고    scopus 로고
    • Prophylactic treatment with FEIBA of a haemophilia A patient with inhibitor: what are the costs, what are the benefits?
    • Siegmund B., Richter H., and Pollmann H. Prophylactic treatment with FEIBA of a haemophilia A patient with inhibitor: what are the costs, what are the benefits?. Haemophilia 11 (2005) 638-641
    • (2005) Haemophilia , vol.11 , pp. 638-641
    • Siegmund, B.1    Richter, H.2    Pollmann, H.3
  • 21
    • 43149116111 scopus 로고    scopus 로고
    • Secondary prophylaxis with recombinant activated factor VII improves health-related quality of life of haemophilia patients with inhibitors
    • Hoots W.K., Ebbesen L.S., Konkle B.A., Auerswald G.K., Roberts H.R., Weatherall J., et al. Secondary prophylaxis with recombinant activated factor VII improves health-related quality of life of haemophilia patients with inhibitors. Haemophilia 14 (2008) 466-475
    • (2008) Haemophilia , vol.14 , pp. 466-475
    • Hoots, W.K.1    Ebbesen, L.S.2    Konkle, B.A.3    Auerswald, G.K.4    Roberts, H.R.5    Weatherall, J.6
  • 23
    • 34548096392 scopus 로고    scopus 로고
    • Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors
    • Konkle B.A., Ebbesen L.S., Erhardtsen E., Bianco R.P., Lissitchkov T., Rusen L., et al. Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors. J Thromb Haemost 5 (2007) 1904-1913
    • (2007) J Thromb Haemost , vol.5 , pp. 1904-1913
    • Konkle, B.A.1    Ebbesen, L.S.2    Erhardtsen, E.3    Bianco, R.P.4    Lissitchkov, T.5    Rusen, L.6
  • 24
    • 34548301664 scopus 로고    scopus 로고
    • Prophylactic treatment of haemophilia patients with inhibitors: clinical experience with recombinant factor VIIa in European Haemophilia Centres
    • Morfini M., Auerswald G., Kobelt R.A., Rivolta G.F., Rodriguez-Martorell J., Scaraggi F.A., et al. Prophylactic treatment of haemophilia patients with inhibitors: clinical experience with recombinant factor VIIa in European Haemophilia Centres. Haemophilia 13 (2007) 502-507
    • (2007) Haemophilia , vol.13 , pp. 502-507
    • Morfini, M.1    Auerswald, G.2    Kobelt, R.A.3    Rivolta, G.F.4    Rodriguez-Martorell, J.5    Scaraggi, F.A.6
  • 25
    • 0034758420 scopus 로고    scopus 로고
    • Effective prophylaxis with daily recombinant factor VIIa (rFVIIa-Novoseven) in a child with high titre inhibitors and a target joint
    • Saxon B.R., Shanks D., Jory C.B., and Williams V. Effective prophylaxis with daily recombinant factor VIIa (rFVIIa-Novoseven) in a child with high titre inhibitors and a target joint. Thromb Haemost 86 (2001) 1126-1127
    • (2001) Thromb Haemost , vol.86 , pp. 1126-1127
    • Saxon, B.R.1    Shanks, D.2    Jory, C.B.3    Williams, V.4
  • 26
    • 19444375983 scopus 로고    scopus 로고
    • Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors
    • Young G., McDaniel M., and Nugent D.J. Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors. Haemophilia 11 (2005) 203-207
    • (2005) Haemophilia , vol.11 , pp. 203-207
    • Young, G.1    McDaniel, M.2    Nugent, D.J.3
  • 27
    • 33750342991 scopus 로고    scopus 로고
    • A retrospective postlicensure survey of FEIBA efficacy and safety
    • DiMichele D., and Negrier C. A retrospective postlicensure survey of FEIBA efficacy and safety. Haemophilia 12 (2006) 352-362
    • (2006) Haemophilia , vol.12 , pp. 352-362
    • DiMichele, D.1    Negrier, C.2
  • 28
    • 0029554996 scopus 로고
    • Clinical update on the use of recombinant factor VII
    • Glazer S., Hedner U., and Falch J.F. Clinical update on the use of recombinant factor VII. Adv Exp Med Biol 386 (1995) 163-174
    • (1995) Adv Exp Med Biol , vol.386 , pp. 163-174
    • Glazer, S.1    Hedner, U.2    Falch, J.F.3
  • 29
    • 17144437423 scopus 로고    scopus 로고
    • Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors
    • Key N.S., Aledort L.M., Beardsley D., Cooper H.A., Davignon G., Ewenstein B.M., et al. Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors. Thromb Haemost 80 (1998) 912-918
    • (1998) Thromb Haemost , vol.80 , pp. 912-918
    • Key, N.S.1    Aledort, L.M.2    Beardsley, D.3    Cooper, H.A.4    Davignon, G.5    Ewenstein, B.M.6
  • 32
    • 34548321383 scopus 로고    scopus 로고
    • A randomized, double-blind trial demonstrating bioequivalence of the current recombinant activated factor VII formulation and a new robust 25 degrees C stable formulation
    • Bysted B.V., Scharling B., Moller T., and Hansen B.L. A randomized, double-blind trial demonstrating bioequivalence of the current recombinant activated factor VII formulation and a new robust 25 degrees C stable formulation. Haemophilia 13 (2007) 527-532
    • (2007) Haemophilia , vol.13 , pp. 527-532
    • Bysted, B.V.1    Scharling, B.2    Moller, T.3    Hansen, B.L.4
  • 33
    • 33947494621 scopus 로고    scopus 로고
    • Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A
    • Sorensen B., Persson E., and Ingerslev J. Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A. Br J Haematol 137 (2007) 158-165
    • (2007) Br J Haematol , vol.137 , pp. 158-165
    • Sorensen, B.1    Persson, E.2    Ingerslev, J.3
  • 34
    • 76149100844 scopus 로고    scopus 로고
    • Enhanced and prolonged efficacy of a novel recombinant FVIIa variant (BAY86-6150) for acute and prophylactic treatments in hemophilia A (HemA) mice
    • Abstract OC-WE-057
    • Liu T., Zhang X., Pan J., Sim D., McLean K., Cui Z., et al. Enhanced and prolonged efficacy of a novel recombinant FVIIa variant (BAY86-6150) for acute and prophylactic treatments in hemophilia A (HemA) mice. J Thromb Haemost 7 Suppl 2 (2009) Abstract OC-WE-057
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 2
    • Liu, T.1    Zhang, X.2    Pan, J.3    Sim, D.4    McLean, K.5    Cui, Z.6
  • 35
    • 76149140821 scopus 로고    scopus 로고
    • Binding to activated platelets and enhanced clotting properties of the recombinant FVIIa analogue Bay7
    • Abstract OC-WE-059
    • Pan J., Kim J., Zhu D., Blank E., Zhang X., Liu T., et al. Binding to activated platelets and enhanced clotting properties of the recombinant FVIIa analogue Bay7. J Thromb Haemost 7 Suppl 2 (2009) Abstract OC-WE-059
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 2
    • Pan, J.1    Kim, J.2    Zhu, D.3    Blank, E.4    Zhang, X.5    Liu, T.6
  • 36
    • 0035923721 scopus 로고    scopus 로고
    • Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity
    • Persson E., Kjalke M., and Olsen O.H. Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity. Proc Natl Acad Sci U S A 98 (2001) 13583-13588
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13583-13588
    • Persson, E.1    Kjalke, M.2    Olsen, O.H.3
  • 38
    • 38349145384 scopus 로고    scopus 로고
    • Efficacy and safety of a new-class hemostatic drug candidate, AV513, in dogs with hemophilia A
    • Prasad S., Lillicrap D., Labelle A., Knappe S., Keller T., Burnett E., et al. Efficacy and safety of a new-class hemostatic drug candidate, AV513, in dogs with hemophilia A. Blood 111 (2008) 672-679
    • (2008) Blood , vol.111 , pp. 672-679
    • Prasad, S.1    Lillicrap, D.2    Labelle, A.3    Knappe, S.4    Keller, T.5    Burnett, E.6


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