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Diabetologia

Volumn 53, Issue 3, 2010, Pages 403-405

Oxidative stress and glucose metabolism-is there a need to revisit effects of insulin treatment?

(1) Humpert, P M a

a UNIVERSITY OF HEIDELBERG (Germany)

Author keywords

Diabetes; Glycaemic variability; Insulin; Oxidative stress; Vascular complications

Indexed keywords

INSULIN; 8-EPI-PROSTAGLANDIN F2ALPHA; ANTIDIABETIC AGENT; GLUCOSE; PROSTAGLANDIN F2 ALPHA;

ANTIOXIDANT ACTIVITY; CLINICAL TRIAL; DIABETIC PATIENT; GLUCOSE METABOLISM; HEART INFARCTION; HUMAN; HYPERGLYCEMIA; HYPERTENSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; NON INSULIN DEPENDENT DIABETES MELLITUS; NOTE; OXIDATIVE STRESS; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; BIOLOGICAL MODEL; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; HYPOGLYCEMIA; INFLAMMATION; METABOLISM; METHODOLOGY; PATHOLOGY;

CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; DINOPROST; GLUCOSE; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INFLAMMATION; INSULIN; MODELS, BIOLOGICAL; OXIDATIVE STRESS; RESEARCH DESIGN;

EID: 77949267109 PISSN: 0012186X EISSN: 14320428 Source Type: Journal
DOI: 10.1007/s00125-009-1652-9 Document Type: Note

Times cited : (5)

References (29)

1
- 20044376702
- The pathobiology of diabetic complications: A unifying mechanism
- DOI 10.2337/diabetes.54.6.1615
- M Brownlee 2005 The pathobiology of diabetic complications: A unifying mechanism Diabetes 54 1615 1625 10.2337/diabetes.54.6.1615 1:CAS:528: DC%2BD2MXltVaisbk%3D 15919781 (Pubitemid 40770750)
- (2005) Diabetes , vol.54 , Issue.6 , pp. 1615-1625
- Brownlee, M.¹

2
- 0036796875
- Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
- DOI 10.1210/er.2001-0039
- JL Evans ID Goldfine BA Maddux GM Grodsky 2002 Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes Endocr Rev 23 599 622 10.1210/er.2001-0039 1:CAS:528:DC%2BD38XosVejsbg%3D 12372842 (Pubitemid 35191625)
- (2002) Endocrine Reviews , vol.23 , Issue.5 , pp. 599-622
- Evans, J.L.¹ Goldfine, I.D.² Maddux, B.A.³ Grodsky, G.M.⁴

3
- 27744453362
- Understanding RAGE, the receptor for advanced glycation end products
- DOI 10.1007/s00109-005-0688-7
- A Bierhaus PM Humpert M Morcos, et al. 2005 Understanding RAGE, the receptor for advanced glycation end products J Mol Med 83 876 886 10.1007/s00109-005-0688-7 1:CAS:528:DC%2BD2MXht1SksbjP 16133426 (Pubitemid 41598688)
- (2005) Journal of Molecular Medicine , vol.83 , Issue.11 , pp. 876-886
- Bierhaus, A.¹ Humpert, P.M.² Morcos, M.³ Wendt, T.⁴ Chavakis, T.⁵ Arnold, B.⁶ Stern, D.M.⁷ Nawroth, P.P.⁸

4
- 0034455878
- Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes
- DOI 10.1210/jc.85.8.2970
- P Mohanty W Hamouda R Garg A Aljada H Ghanim P Dandona 2000 Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes J Clin Endocrinol Metab 85 2970 2973 10.1210/jc.85.8.2970 1:CAS:528: DC%2BD3cXnslahtrc%3D 10946914 (Pubitemid 32269184)
- (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.8 , pp. 2970-2973
- Mohanty, P.¹ Hamouda, W.² Garg, R.³ Aljada, A.⁴ Ghanim, H.⁵ Dandona, P.⁶

5
- 0037339603
- Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor κB in PBMCs
- DOI 10.2337/diabetes.52.3.621
- S Schiekofer M Andrassy J Chen, et al. 2003 Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs Diabetes 52 621 633 10.2337/diabetes.52.3.621 1:CAS:528:DC%2BD3sXitFajsbo%3D 12606501 (Pubitemid 36323567)
- (2003) Diabetes , vol.52 , Issue.3 , pp. 621-633
- Schiekofer, S.¹ Andrassy, M.² Chen, J.³ Rudofsky, G.⁴ Schneider, J.⁵ Wendt, T.⁶ Stefan, N.⁷ Humpert, P.⁸ Fritsche, A.⁹ Stumvoll, M.¹⁰ Schleicher, E.¹¹ Haring, H.-U.¹² Nawroth, P.P.¹³ Bierhaus, A.¹⁴

6
- 33645745733
- Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
- 10.1001/jama.295.14.1681 1:CAS:528:DC%2BD28XjsVequ7k%3D 16609090
- L Monnier E Mas C Ginet, et al. 2006 Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes Jama 295 1681 1687 10.1001/jama.295.14.1681 1:CAS:528:DC%2BD28XjsVequ7k%3D 16609090
- (2006) Jama , vol.295 , pp. 1681-1687
- Monnier, L.¹ Mas, E.² Ginet, C.³

7
- 77949263068
- Regulation of oxidative stress by glycaemic control: Evidence for an independent inhibitory effect of insulin therapy
- 10.1007/s00125-009-1574-6 19890623
- L Monnier C Colette E Mas, et al. 2009 Regulation of oxidative stress by glycaemic control: evidence for an independent inhibitory effect of insulin therapy Diabetologia 10.1007/s00125-009-1574-6 19890623
- (2009) Diabetologia
- Monnier, L.¹ Colette, C.² Mas, E.³

8
- 70349653641
- Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes
- 10.2337/dc09-0109 19549736
- ES Kilpatrick AS Rigby SL Atkin 2009 Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes Diabetes Care 32 1901 1903 10.2337/dc09-0109 19549736
- (2009) Diabetes Care , vol.32 , pp. 1901-1903
- Kilpatrick, E.S.¹ Rigby, A.S.² Atkin, S.L.³

9
- 64749114318
- Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: The HEART2D trial
- 10.2337/dc08-1671 1:CAS:528:DC%2BD1MXjvVyqsbk%3D 19246588
- I Raz PW Wilson K Strojek, et al. 2009 Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: the HEART2D trial Diabetes Care 32 381 386 10.2337/dc08-1671 1:CAS:528:DC%2BD1MXjvVyqsbk%3D 19246588
- (2009) Diabetes Care , vol.32 , pp. 381-386
- Raz, I.¹ Wilson, P.W.² Strojek, K.³

10
- 69949164144
- Glucose variability does not contribute to the development of peripheral and autonomic neuropathy in type 1 diabetes: Data from the DCCT
- 10.1007/s00125-009-1473-x 1:STN:280:DC%2BD1Mngt1Gmtw%3D%3D 19672575
- SE Siegelaar ES Kilpatrick AS Rigby SL Atkin JB Hoekstra JH Devries 2009 Glucose variability does not contribute to the development of peripheral and autonomic neuropathy in type 1 diabetes: data from the DCCT Diabetologia 52 2229 2232 10.1007/s00125-009-1473-x 1:STN:280:DC%2BD1Mngt1Gmtw%3D%3D 19672575
- (2009) Diabetologia , vol.52 , pp. 2229-2232
- Siegelaar, S.E.¹ Kilpatrick, E.S.² Rigby, A.S.³ Atkin, S.L.⁴ Hoekstra, J.B.⁵ Devries, J.H.⁶

11
- 67349251550
- Megatrials in type 2 diabetes. from excitement to frustration?
- 10.1007/s00125-009-1352-5 1:CAS:528:DC%2BD1MXms1yhsL4%3D 19373446
- S Del Prato 2009 Megatrials in type 2 diabetes. From excitement to frustration? Diabetologia 52 1219 1226 10.1007/s00125-009-1352-5 1:CAS:528:DC%2BD1MXms1yhsL4%3D 19373446
- (2009) Diabetologia , vol.52 , pp. 1219-1226
- Del Prato, S.¹

12
- 33744483414
- Insulin decreases intracellular oxidative stress in patients with type 2 diabetes mellitus
- DOI 10.1016/j.metabol.2006.01.003, PII S0026049506000412
- MC Bravi A Armiento O Laurenti, et al. 2006 Insulin decreases intracellular oxidative stress in patients with type 2 diabetes mellitus Metabolism 55 691 695 10.1016/j.metabol.2006.01.003 1:CAS:528: DC%2BD28XjvVGmu7o%3D 16631447 (Pubitemid 44316511)
- (2006) Metabolism: Clinical and Experimental , vol.55 , Issue.5 , pp. 691-695
- Bravi, M.C.¹ Armiento, A.² Laurenti, O.³ Cassone-Faldetta, M.⁴ De Luca, O.⁵ Moretti, A.⁶ De Mattia, G.⁷

13
- 70349859675
- Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications
- 10.1007/s00125-009-1458-9 1:CAS:528:DC%2BD1MXht1Cis7jE 19636529
- A Bierhaus PP Nawroth 2009 Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications Diabetologia 52 2251 2263 10.1007/s00125-009-1458-9 1:CAS:528:DC%2BD1MXht1Cis7jE 19636529
- (2009) Diabetologia , vol.52 , pp. 2251-2263
- Bierhaus, A.¹ Nawroth, P.P.²

14
- 0034746443
- Insulin inhibits NFκB and MCP-1 expression in human aortic endothelial cells
- DOI 10.1210/jc.86.1.450
- A Aljada H Ghanim R Saadeh P Dandona 2001 Insulin inhibits NFkappaB and MCP-1 expression in human aortic endothelial cells J Clin Endocrinol Metab 86 450 453 10.1210/jc.86.1.450 1:CAS:528:DC%2BD3MXhtVGntLw%3D 11232040 (Pubitemid 32109834)
- (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.1 , pp. 450-453
- Aljada, A.¹ Ghanim, H.² Saadeh, R.³ Dandona, P.⁴

15
- 0034915177
- Insulin inhibits intranuclear nuclear factor κB and stimulates IκB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
- DOI 10.1210/jc.86.7.3257
- P Dandona A Aljada P Mohanty, et al. 2001 Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 86 3257 3265 10.1210/jc.86.7.3257 1:CAS:528:DC%2BD3MXlt1GjtLk%3D 11443198 (Pubitemid 32674120)
- (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.7 , pp. 3257-3265
- Dandona, P.¹ Aljada, A.² Mohanty, P.³ Ghanim, H.⁴ Hamouda, W.⁵ Assian, E.⁶ Ahmad, S.⁷

16
- 58549095307
- Insulin as an anti-inflammatory and antiatherogenic modulator
- 10.1016/j.jacc.2008.10.038 1:CAS:528:DC%2BD1MXhtlSnsb8%3D 19179212
- P Dandona A Chaudhuri H Ghanim P Mohanty 2009 Insulin as an anti-inflammatory and antiatherogenic modulator J Am Coll Cardiol 53 S14 S20 10.1016/j.jacc.2008.10.038 1:CAS:528:DC%2BD1MXhtlSnsb8%3D 19179212
- (2009) J Am Coll Cardiol , vol.53
- Dandona, P.¹ Chaudhuri, A.² Ghanim, H.³ Mohanty, P.⁴

17
- 0028030813
- Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
- 10.1172/JCI117433 1:CAS:528:DyaK2cXlslWjsLY%3D 8083357
- HO Steinberg G Brechtel A Johnson N Fineberg AD Baron 1994 Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release J Clin Invest 94 1172 1179 10.1172/JCI117433 1:CAS:528:DyaK2cXlslWjsLY%3D 8083357
- (1994) J Clin Invest , vol.94 , pp. 1172-1179
- Steinberg, H.O.¹ Brechtel, G.² Johnson, A.³ Fineberg, N.⁴ Baron, A.D.⁵

18
- 0037637412
- Insulin-induced decreases in aortic wave reflection and central systolic pressure are impaired in type 2 diabetes
- 10.2337/diacare.25.12.2314 1:CAS:528:DC%2BD38Xps1KksLo%3D 12453979
- M Tamminen J Westerbacka S Vehkavaara H Yki-Jarvinen 2002 Insulin-induced decreases in aortic wave reflection and central systolic pressure are impaired in type 2 diabetes Diabetes Care 25 2314 2319 10.2337/diacare.25.12.2314 1:CAS:528:DC%2BD38Xps1KksLo%3D 12453979
- (2002) Diabetes Care , vol.25 , pp. 2314-2319
- Tamminen, M.¹ Westerbacka, J.² Vehkavaara, S.³ Yki-Jarvinen, H.⁴

19
- 0032895748
- Diminished wave reflection in the aorta. A novel physiological action of insulin on large blood vessels
- 1:CAS:528:DyaK1MXjslSqtbY%3D 10334797
- J Westerbacka I Wilkinson J Cockcroft T Utriainen S Vehkavaara H Yki-Jarvinen 1999 Diminished wave reflection in the aorta. A novel physiological action of insulin on large blood vessels Hypertension 33 1118 1122 1:CAS:528:DyaK1MXjslSqtbY%3D 10334797
- (1999) Hypertension , vol.33 , pp. 1118-1122
- Westerbacka, J.¹ Wilkinson, I.² Cockcroft, J.³ Utriainen, T.⁴ Vehkavaara, S.⁵ Yki-Jarvinen, H.⁶

20
- 0342615049
- Insulin therapy improves endothelial function in type 2 diabetes
- 1:CAS:528:DC%2BD3cXht1yqsLw%3D 10669655
- S Vehkavaara S Makimattila A Schlenzka J Vakkilainen J Westerbacka H Yki-Jarvinen 2000 Insulin therapy improves endothelial function in type 2 diabetes Arterioscler Thromb Vasc Biol 20 545 550 1:CAS:528:DC%2BD3cXht1yqsLw%3D 10669655
- (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 545-550
- Vehkavaara, S.¹ Makimattila, S.² Schlenzka, A.³ Vakkilainen, J.⁴ Westerbacka, J.⁵ Yki-Jarvinen, H.⁶

21
- 44649141804
- Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling
- DOI 10.2119/2007-00052.Humpert
- PM Humpert Z Djuric U Zeuge, et al. 2008 Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling Mol Med 14 301 308 10.2119/2007-00052.Humpert 1:CAS:528:DC%2BD1cXntV2gtLs%3D 18309377 (Pubitemid 351785703)
- (2008) Molecular Medicine , vol.14 , Issue.5-6 , pp. 301-308
- Humpert, P.M.¹ Djuric, Z.² Zeuge, U.³ Oikonomou, D.⁴ Seregin, Y.⁵ Laine, K.⁶ Eckstein, V.⁷ Nawroth, P.P.⁸ Bierhaus, A.⁹

22
- 20144387992
- SDF-1 genotype influences insulin-dependent mobilization of adult progenitor cells in type 2 diabetes
- DOI 10.2337/diacare.28.4.934
- PM Humpert R Neuwirth MJ Battista, et al. 2005 SDF-1 genotype influences insulin-dependent mobilization of adult progenitor cells in type 2 diabetes Diabetes Care 28 934 936 10.2337/diacare.28.4.934 15793201 (Pubitemid 40434501)
- (2005) Diabetes Care , vol.28 , Issue.4 , pp. 934-936
- Humpert, P.M.¹ Neuwirth, R.² Battista, M.J.³ Voronko, O.⁴ Von Eynatten, M.⁵ Konrade, I.⁶ Rudofsky Jr., G.⁷ Wendt, T.⁸ Hamann, A.⁹ Morcos, M.¹⁰ Nawroth, P.P.¹¹ Bierhaus, A.¹²

23
- 48649097304
- Maternal insulin therapy increases fetal endothelial progenitor cells during diabetic pregnancy
- 10.2337/dc07-1996 18162496
- GP Fadini I Baesso C Agostini, et al. 2008 Maternal insulin therapy increases fetal endothelial progenitor cells during diabetic pregnancy Diabetes Care 31 808 810 10.2337/dc07-1996 18162496
- (2008) Diabetes Care , vol.31 , pp. 808-810
- Fadini, G.P.¹ Baesso, I.² Agostini, C.³

24
- 2342625311
- Insulin Generates Free Radicals by an NAD(P)H, Phosphatidylinositol 3′-Kinase-Dependent Mechanism in Human Skin Fibroblasts Ex Vivo
- DOI 10.2337/diabetes.53.5.1344
- G Ceolotto M Bevilacqua I Papparella, et al. 2004 Insulin generates free radicals by an NAD(P)H, phosphatidylinositol 3-kinase-dependent mechanism in human skin fibroblasts ex vivo Diabetes 53 1344 1351 10.2337/diabetes.53.5.1344 1:CAS:528:DC%2BD2cXjslKhsrc%3D 15111505 (Pubitemid 38569022)
- (2004) Diabetes , vol.53 , Issue.5 , pp. 1344-1351
- Ceolotto, G.¹ Bevilacqua, M.² Papparella, I.³ Baritono, E.⁴ Franco, L.⁵ Corvaja, C.⁶ Mazzoni, M.⁷ Semplicini, A.⁸ Avogaro, A.⁹

25
- 0037097039
- Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
- DOI 10.1016/S0140-6736(02)08905-5
- JL Chiasson RG Josse R Gomis M Hanefeld A Karasik M Laakso 2002 Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial Lancet 359 2072 2077 10.1016/S0140-6736(02)08905-5 1:CAS:528: DC%2BD38XkslGhs7g%3D 12086760 (Pubitemid 34680970)
- (2002) Lancet , vol.359 , Issue.9323 , pp. 2072-2077
- Chiasson, J.-L.¹ Josse, R.G.² Gomis, R.³ Hanefeld, M.⁴ Karasik, A.⁵ Laakso, M.⁶

26
- 0038455703
- Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: The STOP-NIDDM trial
- DOI 10.1001/jama.290.4.486
- JL Chiasson RG Josse R Gomis M Hanefeld A Karasik M Laakso 2003 Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial Jama 290 486 494 10.1001/jama.290.4.486 1:CAS:528:DC%2BD3sXls1yjs7c%3D 12876091 (Pubitemid 37430502)
- (2003) Journal of the American Medical Association , vol.290 , Issue.4 , pp. 486-494
- Chiasson, J.-L.¹ Josse, R.G.² Gomis, R.³ Hanefeld, M.⁴ Karasik, A.⁵ Laakso, M.⁶

27
- 70350179649
- Is glycaemia or insulin dose the stronger risk factor for coronary artery disease in type 1 diabetes?
- 10.1177/1479164109336041
- B Conway T Costacou T Orchard 2009 Is glycaemia or insulin dose the stronger risk factor for coronary artery disease in type 1 diabetes? Diab Vasc Dis Res 6 223 230 10.1177/1479164109336041
- (2009) Diab Vasc Dis Res , vol.6 , pp. 223-230
- Conway, B.¹ Costacou, T.² Orchard, T.³

28
- 33645561623
- Isoprostanes and other markers of peroxidation in atherosclerosis
- 10.1080/13547500500215084 1:CAS:528:DC%2BD2MXht1eltb7M 16298908
- P Patrignani S Tacconelli 2005 Isoprostanes and other markers of peroxidation in atherosclerosis Biomarkers 10 Suppl 1 S24 S29 10.1080/13547500500215084 1:CAS:528:DC%2BD2MXht1eltb7M 16298908
- (2005) Biomarkers , vol.10 , Issue.SUPPL 1
- Patrignani, P.¹ Tacconelli, S.²

29
- 0034709065
- Hyperinsulinemia and the risk of cardiovascular death and acute coronary and cerebrovascular events in men: The Kuopio Ischaemic Heart Disease Risk Factor Study
- 10.1001/archinte.160.8.1160 1:STN:280:DC%2BD3c3kvVCksA%3D%3D 10789610
- HM Lakka TA Lakka J Tuomilehto J Sivenius JT Salonen 2000 Hyperinsulinemia and the risk of cardiovascular death and acute coronary and cerebrovascular events in men: the Kuopio Ischaemic Heart Disease Risk Factor Study Arch Intern Med 160 1160 1168 10.1001/archinte.160.8.1160 1:STN:280:DC%2BD3c3kvVCksA%3D%3D 10789610
- (2000) Arch Intern Med , vol.160 , pp. 1160-1168
- Lakka, H.M.¹ Lakka, T.A.² Tuomilehto, J.³ Sivenius, J.⁴ Salonen, J.T.⁵

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