Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 381, Issue 2, 2010, Pages 161-169

  Venner, Monica ^a   Peters, Jette ^b   Höhensteiger, Nina ^a   Schock, Birthe ^a   Bornhorst, Alexa ^b   Grube, Markus ^b   Adam, Ulrike ^b   Scheuch, Eberhard ^b   Weitschies, Werner ^b   Rosskopf, Dieter ^b   Kroemer, Heyo K ^b   Siegmund, Werner ^b  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Alveolar macrophage; Foals; P glycoprotein; Pulmonary pharmacokinetics; Rifampicin; Tulathromycin

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; DRAXXIN; MACROLIDE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER 1; RIFAMPICIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; TULATHROMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CELL STRAIN; CLINICAL EXAMINATION; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG SCREENING; ECHOGRAPHY; EPITHELIAL LINING FLUID; EPITHELIUM; FEMALE; FOAL; GENE EXPRESSION; GENETIC TRANSFECTION; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MAXIMUM PLASMA CONCENTRATION; MEMBRANE VESICLE; MONOTHERAPY; NONHUMAN; NUCLEOTIDE SEQUENCE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEADY STATE; TREATMENT DURATION;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTITUBERCULAR; AREA UNDER CURVE; BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; DISACCHARIDES; DOGS; DRUG INTERACTIONS; FEMALE; HETEROCYCLIC COMPOUNDS; HORSES; MALE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PULMONARY ALVEOLI; RIFAMPIN; RNA, MESSENGER;

EID: 77949264196     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-009-0481-1     Document Type: Article

References (36)

1. N Albermann FH Schmitz-Winnenthal K Z'graggen, et al. 2005 Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver Biochem Pharmacol 70 949 958 10.1016/j.bcp.2005.06.018 1:CAS:528:DC%2BD2MXnslOqurk%3D 16054595 (Pubitemid 41138860)
2. DR Baldwin R Wise JM Andrews JP Ashby D Honeybourne 1990 Azithromycin concentrations at the sites of pulmonary infection Eur Respir J 3 886 890 1:STN:280:DyaK3M7ltlCktA%3D%3D 1963411
3. HA Benchaoui M Nowakowski J Sherington TG Rowan SJ Sunderland 2004 Pharmacokinetics and lung tissue concentrations of tulathromycin in swine J Vet Pharmacol Ther 27 203 210 10.1111/j.1365-2885.2004.00586.x 1:CAS:528: DC%2BD2cXotVCgtrk%3D 15305848 (Pubitemid 39141605)
4. P Beringer KM Huynh J Kriengkauykiat, et al. 2005 Absolute bioavailability and intracellular pharmacokinetics of azithromycin in patients with cystic fibrosis Antimicrob Agents Chemother 49 5013 5017 10.1128/AAC.49.12.5013-5017.2005 1:CAS:528:DC%2BD2MXhtlSqsrzO 16304166 (Pubitemid 41778914)
5. M Bosnar Z Kelneric V Munic V Erakovic MJ Parnham 2005 Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin Antimicrob Agents Chemother 49 2372 2377 10.1128/AAC.49.6.2372-2377. 2005 1:CAS:528:DC%2BD2MXkvFCgs7o%3D 15917536 (Pubitemid 40734469)
6. JE Conte Jr JA Golden S Duncan E McKenna E Zurlinden 1995 Intrapulmonary pharmacokinetics of clarithromycin and of erythromycin Antimicrob Agents Chemother 39 334 338 1:CAS:528:DyaK2MXjsFCisbY%3D 7726492
7. D Damiani M Michieli A Michelutti, et al. 1993 Expression of multidrug resistance gene (MDR-1) in human normal leukocytes Haematologica 78 12 17 1:STN:280:DyaK3s3lvFGisQ%3D%3D 8098310 (Pubitemid 23144714)
8. European Medicines Agency (EMEA), Committee For Veterinary Medicinal Products (2004) Tulathromycin Summary Report (2)
9. NA Evans 2005 Tulathromycin: an overview of a new triamilide antibiotic for livestock respiratory disease Vet Ther 6 83 95 16094557
10. O Fardel V Lecureur P Loyer A Guillouzo 1995 Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells Biochem Pharmacol 49 1255 1260 10.1016/0006-2952(95)00045-2 1:CAS:528:DyaK2MXlvVGhtr0%3D 7763306
11. B Farr GL Mandell 1982 Rifampin Med Clin North Am 66 157 168 1:CAS:528:DyaL38Xps12nsQ%3D%3D 7038325
12. D Galer S Hessong B Beato, et al. 2004 An analytical method for the analysis of tulathromycin, an equilibrating triamilide, in bovine and porcine plasma and lung J Agric Food Chem 52 2179 2191 10.1021/jf0351624 1:CAS:528:DC%2BD2cXisFaqtrw%3D 15080618
13. CJ Hillidge 1987 Use of erythromycin-rifampin combination in treatment of Rhodococcus equi pneumonia Vet Microbiol 14 337 342 10.1016/0378-1135(87)90121- 0 1:STN:280:DyaL1c%2FksVeqsg%3D%3D 3314109 (Pubitemid 18016066)
14. St Jacks St Gíguère RR Grouwall, et al. 2001 Pharmacokinetics of azithromycin and concentration in body fluids and bronchoalveolar cells in foals Am J Vet Res 62 1870 1875 10.2460/ajvr.2001.62. 1870 1:CAS:528:DC%2BD38XosFA%3D 11763173
15. WT Klimecki BW Futscher TM Grogan WS Dalton 1994 P-glycoprotein expression and function in circulating blood cells from normal volunteers Blood 83 2451 2458 1:CAS:528:DyaK2cXksFCmsb8%3D 7513198
16. GA Kullak-Ublick MG Ismair B Stieger, et al. 2001 Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver Gastroenterology 120 525 533 10.1053/gast.2001.21176 1:CAS:528:DC%2BD3MXhtlKltbo%3D 11159893
17. MT Labro H Abdelghaffar C Babin-Chevaye 2004 Interaction of the new ketolide ABT-773 (cethromycin) with human polymorphonuclear neutrophils and the phagocytic cell line PLB-985 in vitro Antimicrob Agents Chemother 48 1096 1104 10.1128/AAC.48.4.1096-1104.2004 1:CAS:528:DC%2BD2cXjtVKruro%3D 15047507 (Pubitemid 38405460)
18. MT Labro C Babin-Chevaye M Mergey 2005 Accumulation of azithromycin and roxithromycin in tracheal epithelial fetal cell lines expressing wild type or mutated cystic fibrosis transmembrane conductance regulator protein (CFTR) J Chemother 17 385 392 1:CAS:528:DC%2BD2MXhtVyktLzI 16167517
19. YY Lau H Okochi Y Huang LZ Benet 2006 Multiple transporters affect the disposition of atorvastatin and its two active hydroxy metabolites: application of in vitro and ex situ systems J Pharmacol Exp Ther 316 762 771 10.1124/jpet.105.093088 1:CAS:528:DC%2BD28XhtlWqtrg%3D 16258024 (Pubitemid 43131004)
20. B Laupeze L Amiot L Payen, et al. 2001 Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral blood Life Sci 68 1323 1331 10.1016/S0024-3205(00)01026-2 1:CAS:528:DC%2BD3MXhs12gsr4%3D 11233999 (Pubitemid 32168035)
21. WG Meijer JF Prescott 2004 Rhodococcus equi Vet Res 35 383 396 10.1051/vetres:2004024 1:CAS:528:DC%2BD2cXotFKhsL8%3D 15236672 (Pubitemid 39161929)
22. T Nichterlein M Kretschmar A Schadt, et al. 1998 Reduced intracellular activity of antibiotics against Listeria monocytogenes in multidrug resistant cells Int J Antimicrob Agents 10 119 125 10.1016/S0924-8579(98)00030-2 1:CAS:528:DyaK1cXltFyltrg%3D 9716288 (Pubitemid 28334193)
23. MA Nowakowski PB Inskeep JE Risk, et al. 2004 Pharmacokinetics and lung tissue concentrations of tulathromycin, a new triamilide antibiotic, in cattle Vet Ther 5 60 74 15150731
24. KM Olsen G San Pedro LP Gann PO Gubbins DM Halinski GD Campbell Jr 1996 Intrapulmonary pharmacokinetics of azithromycin in healthy volunteers given five oral doses Antimicrob Agents Chemother 40 2582 2585 1:CAS:528: DyaK28Xms1Smsbs%3D 8913469
25. S Oswald S Haenisch C Fricke, et al. 2006 Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans Clin Pharmacol Ther 79 206 217 10.1016/j.clpt.2005.11.004 1:CAS:528:DC%2BD28XitVKhur0%3D 16513445 (Pubitemid 43297013)
26. KA Rodvold LH Danziger MH Gotfried 2003 Steady-state plasma and bronchopulmonary concentrations of intravenous levofloxacin and azithromycin in healthy adults Antimicrob Agents Chemother 47 2450 2457 10.1128/AAC.47.8.2450- 2457.2003 1:CAS:528:DC%2BD3sXlvFCmu74%3D 12878504 (Pubitemid 36919444)
27. E Scheuch J Spieker M Venner W Siegmund 2007 Quantitative determination of the macrolide antibiotic tulathromycin in plasma and broncho-alveolar cells of foals using tandem mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci 850 464 470 10.1016/j.jchromb.2006.12.034 1:CAS:528: DC%2BD2sXkslOjsr8%3D 17267304 (Pubitemid 46618190)
28. A Seithel S Eberl K Singer, et al. 2007 The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3 Drug Metab Dispos 35 779 786 10.1124/dmd.106.014407 1:CAS:528: DC%2BD2sXlsVWmtbY%3D 17296622 (Pubitemid 46641549)
29. C Seral S Carryn PM Tulkens F Van Bambeke 2003 Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus J Antimicrob Chemother 51 1167 1173 10.1093/jac/dkg223 1:CAS:528:DC%2BD3sXjsVKltr4%3D 12697643 (Pubitemid 36622073)
30. C Seral JM Michot H Chanteux MP Mingeot-Leclercq PM Tulkens F Van Bambeke 2003 Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages Antimicrob Agents Chemother 47 1047 1051 10.1128/AAC.47.3.1047-1051.2003 1:CAS:528:DC%2BD3sXhslWitLw%3D 12604540 (Pubitemid 36254233)
31. M Sugie E Asakura YL Zhao, et al. 2004 Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin Antimicrob Agents Chemother 48 809 814 10.1128/AAC.48.3.809-814.2004 1:CAS:528:DC%2BD2cXitVGhtrw%3D 14982769 (Pubitemid 38280329)
32. RG Tirona BF Leake AW Wolkoff RB Kim 2003 Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation J Pharmacol Exp Ther 304 223 228 10.1124/jpet.102.043026 1:CAS:528:DC%2BD3sXht1Shtg%3D%3D 12490595 (Pubitemid 36008932)
33. M van der Deen EG de Vries W Timens RJ Scheper H Timmer-Bosscha DS Postma 2005 ATP-binding cassette (ABC) transporters in normal and pathological lung Respir Res 6 59 10.1186/1465-9921-6-59 15967026 (Pubitemid 41410176)
34. SR Vavricka J Van Montfoort HR Ha PJ Meier K Fattinger 2002 Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver Hepatology 36 164 172 10.1053/jhep.2002.34133 1:CAS:528:DC%2BD38Xlslyru7c%3D 12085361 (Pubitemid 34700774)
35. C Xu CY Li AN Kong 2005 Induction of phase I, II and III drug metabolism/transport by xenobiotics Arch Pharm Res 28 249 268 10.1007/BF02977789 1:CAS:528:DC%2BD2MXjt1Krtb0%3D 15832810
36. HM Ziglam DR Baldwin I Daniels JM Andrew RG Finch 2002 Rifampicin concentrations in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum following a single 600 mg oral dose in patients undergoing fibre-optic bronchoscopy J Antimicrob Chemother 50 1011 1015 10.1093/jac/dkf214 1:CAS:528:DC%2BD38XptlOis7c%3D 12461025 (Pubitemid 36032825)