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Volumn 29, Issue 9, 2010, Pages 1303-1315

Src family tyrosine kinases-driven colon cancer cell invasion is induced by Csk membrane delocalization

Author keywords

Colorectal cancer; Csk; Invasion; Oncogenic signalling; Tyrosine kinase Src

Indexed keywords

BINDING PROTEIN; GLYCOSPHINGOLIPID; PHOSPHOPROTEIN; PROTEIN TYROSINE KINASE;

EID: 77949262987     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.450     Document Type: Article
Times cited : (51)

References (47)
  • 3
    • 7944223078 scopus 로고    scopus 로고
    • Structure and regulation of Src family kinases
    • Boggon TJ, Eck MJ. (2004). Structure and regulation of Src family kinases. Oncogene 23: 7918-7927.
    • (2004) Oncogene , vol.23 , pp. 7918-7927
    • Boggon, T.J.1    Eck, M.J.2
  • 4
    • 24944563129 scopus 로고    scopus 로고
    • C-Abl tyrosine kinase regulates a Rac/JNK and a Rac/Nox pathway for DNA synthesis and c-myc expression induced by growth factors
    • Boureux A, Furstoss O, Simon V, Roche S. (2005). c-Abl tyrosine kinase regulates a Rac/JNK and a Rac/Nox pathway for DNA synthesis and c-myc expression induced by growth factors. J Cell Sci 118: 3717-3726.
    • (2005) J Cell Sci , vol.118 , pp. 3717-3726
    • Boureux, A.1    Furstoss, O.2    Simon, V.3    Roche, S.4
  • 5
    • 0342313755 scopus 로고    scopus 로고
    • Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
    • Brdicka T, Pavlistova D, Leo A, Bruyns E, Korinek V, Angelisova P, et al. (2000). Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation. J Exp Med 191: 1591-1604.
    • (2000) J Exp Med , vol.191 , pp. 1591-1604
    • Brdicka, T.1    Pavlistova, D.2    Leo, A.3    Bruyns, E.4    Korinek, V.5    Angelisova, P.6
  • 6
    • 0035395989 scopus 로고    scopus 로고
    • Reduced C-terminal Src kinase activity is correlated inversely with pp60(c-src) activity in colorectal carcinoma
    • Cam WR, Masaki T, Shiratori Y, Kato N, Ikenoue T, Okamoto M, et al. (2001). Reduced C-terminal Src kinase activity is correlated inversely with pp60(c-src) activity in colorectal carcinoma. Cancer 92: 61-70.
    • (2001) Cancer , vol.92 , pp. 61-70
    • Cam, W.R.1    Masaki, T.2    Shiratori, Y.3    Kato, N.4    Ikenoue, T.5    Okamoto, M.6
  • 7
    • 18244377636 scopus 로고    scopus 로고
    • N-cadherin association with lipid rafts regulates its dynamic assembly at cell-cell junctions in C2C12 myoblasts
    • Causeret M, Taulet N, Comunale F, Favard C, Gauthier-Rouviere C. (2005). N-cadherin association with lipid rafts regulates its dynamic assembly at cell-cell junctions in C2C12 myoblasts. Mol Biol Cell 16: 2168-2180.
    • (2005) Mol Biol Cell , vol.16 , pp. 2168-2180
    • Causeret, M.1    Taulet, N.2    Comunale, F.3    Favard, C.4    Gauthier-Rouviere, C.5
  • 8
    • 35648989974 scopus 로고    scopus 로고
    • The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities
    • Collin G, Franco M, Simon V, Benistant C, Roche S. (2007). The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities. Mol Cell Biol 27: 7631-7640.
    • (2007) Mol Cell Biol , vol.27 , pp. 7631-7640
    • Collin, G.1    Franco, M.2    Simon, V.3    Benistant, C.4    Roche, S.5
  • 9
    • 40649125574 scopus 로고    scopus 로고
    • Cell growth, global phosphotyrosine elevation, and c-Met phosphoryla-tion through Src family kinases in colorectal cancer cells
    • Emaduddin M, Bicknell DC, Bodmer WF, Feller SM. (2008). Cell growth, global phosphotyrosine elevation, and c-Met phosphoryla-tion through Src family kinases in colorectal cancer cells. Proc Natl Acad Sci USA 105: 2358-2362.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2358-2362
    • Emaduddin, M.1    Bicknell, D.C.2    Bodmer, W.F.3    Feller, S.M.4
  • 10
    • 1842584776 scopus 로고    scopus 로고
    • Newest findings on the oldest oncogene; How activated src does it
    • Frame MC. (2004). Newest findings on the oldest oncogene; how activated src does it. J Cell Sci 117: 989-998.
    • (2004) J Cell Sci , vol.117 , pp. 989-998
    • Frame, M.C.1
  • 11
    • 3543071011 scopus 로고    scopus 로고
    • Transmembrane adaptor proteins: Organizers of immunoreceptor signalling
    • Horejsi V, Zhang W, Schraven B. (2004). Transmembrane adaptor proteins: organizers of immunoreceptor signalling. Nat Rev Immunol 4: 603-616.
    • (2004) Nat Rev Immunol , vol.4 , pp. 603-616
    • Horejsi, V.1    Zhang, W.2    Schraven, B.3
  • 12
    • 0027289232 scopus 로고
    • Disruption of the Csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice
    • Imamoto A, Soriano P. (1993). Disruption of the Csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell 73: 1117-1124.
    • (1993) Cell , vol.73 , pp. 1117-1124
    • Imamoto, A.1    Soriano, P.2
  • 13
    • 33846015045 scopus 로고    scopus 로고
    • Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimu-lated cells
    • Ingley E, Schneider JR, Payne CJ, McCarthy DJ, Harder KW, Hibbs ML, et al. (2006). Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimu-lated cells. J Biol Chem 281: 31920-31929.
    • (2006) J Biol Chem , vol.281 , pp. 31920-31929
    • Ingley, E.1    Schneider, J.R.2    Payne, C.J.3    McCarthy, D.J.4    Harder, K.W.5    Hibbs, M.L.6
  • 14
    • 0032932248 scopus 로고    scopus 로고
    • Activating SRC mutation in a subset of advanced human colon cancers
    • Irby RB, Mao W, Coppola D, Kang J, Loubeau JM, Trudeau W, et al. (1999). Activating SRC mutation in a subset of advanced human colon cancers. Nat Genet 21: 187-190.
    • (1999) Nat Genet , vol.21 , pp. 187-190
    • Irby, R.B.1    Mao, W.2    Coppola, D.3    Kang, J.4    Loubeau, J.M.5    Trudeau, W.6
  • 15
    • 2542423863 scopus 로고    scopus 로고
    • The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism
    • Ishizawar RC, Tice DA, Karaoli T, Parsons SJ. (2004). The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism. J Biol Chem 279: 23773-23781.
    • (2004) J Biol Chem , vol.279 , pp. 23773-23781
    • Ishizawar, R.C.1    Tice, D.A.2    Karaoli, T.3    Parsons, S.J.4
  • 16
    • 0034720166 scopus 로고    scopus 로고
    • Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
    • Kawabuchi M, Satomi Y, Takao T, Shimonishi Y, Nada S, Nagai K, et al. (2000). Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature 404: 999-1003.
    • (2000) Nature , vol.404 , pp. 999-1003
    • Kawabuchi, M.1    Satomi, Y.2    Takao, T.3    Shimonishi, Y.4    Nada, S.5    Nagai, K.6
  • 17
    • 0027958978 scopus 로고
    • Rapid and efficient purification of Src homology 2 domain-containing proteins: Fyn, Csk and phosphatidylinositol 3-kinase p85
    • Koegl M, Kypta RM, Bergman M, Alitalo K, Courtneidge SA. (1994). Rapid and efficient purification of Src homology 2 domain-containing proteins: Fyn, Csk and phosphatidylinositol 3-kinase p85. Biochem J 302: 737-744.
    • (1994) Biochem J , vol.302 , pp. 737-744
    • Koegl, M.1    Kypta, R.M.2    Bergman, M.3    Alitalo, K.4    Courtneidge, S.A.5
  • 18
    • 21244439543 scopus 로고    scopus 로고
    • Down-regulation of the tumor suppressor gene C-terminal Src kinase: An early event during premalignant colonic epithelial hyperproliferation
    • Kunte DP, Wali RK, Koetsier JL, Hart J, Kostjukova MN, Kilimnik AY, et al. (2005). Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation. FEBS Lett 579: 3497-3502.
    • (2005) FEBS Lett , vol.579 , pp. 3497-3502
    • Kunte, D.P.1    Wali, R.K.2    Koetsier, J.L.3    Hart, J.4    Kostjukova, M.N.5    Kilimnik, A.Y.6
  • 19
    • 0033659710 scopus 로고    scopus 로고
    • Constitutive and growth factor-regulated phosphor-ylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: Identification of a c-Src/Cav-1/Grb7 signaling cassette
    • Lee H, Volonte D, Galbiati F, Iyengar P, Lublin DM, Bregman DB, et al. (2000). Constitutive and growth factor-regulated phosphor-ylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette. Mol Endocrinol 14: 1750-1775.
    • (2000) Mol Endocrinol , vol.14 , pp. 1750-1775
    • Lee, H.1    Volonte, D.2    Galbiati, F.3    Iyengar, P.4    Lublin, D.M.5    Bregman, D.B.6
  • 20
    • 65549140324 scopus 로고    scopus 로고
    • Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates Src invasive activity in advanced colon carcinoma cells
    • Leroy C, Fialin C, Sirvent A, Simon V, Urbach S, Poncet J, et al. (2009). Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates Src invasive activity in advanced colon carcinoma cells. Cancer Res 69: 2279-2286.
    • (2009) Cancer Res , vol.69 , pp. 2279-2286
    • Leroy, C.1    Fialin, C.2    Sirvent, A.3    Simon, V.4    Urbach, S.5    Poncet, J.6
  • 21
    • 34247119239 scopus 로고    scopus 로고
    • PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation
    • Liang F, Liang J, Wang WQ, Sun JP, Udho E, Zhang ZY. (2007). PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation. J Biol Chem 282: 5413-5419.
    • (2007) J Biol Chem , vol.282 , pp. 5413-5419
    • Liang, F.1    Liang, J.2    Wang, W.Q.3    Sun, J.P.4    Udho, E.5    Zhang, Z.Y.6
  • 22
    • 6844259884 scopus 로고    scopus 로고
    • Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential
    • Mao W, Irby R, Coppola D, Fu L, Wloch M, Turner J, et al. (1997). Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential. Oncogene 15: 3083-3090. (Pubitemid 28043487)
    • (1997) Oncogene , vol.15 , Issue.25 , pp. 3083-3090
    • Mao, W.1    Irby, R.2    Coppola, D.3    Fu, L.4    Wloch, M.5    Turner, J.6    Yu, H.7    Garcia, R.8    Jove, R.9    Yeatman, T.J.10
  • 23
    • 40849088147 scopus 로고    scopus 로고
    • Roles of plasma membrane-associated sialidase NEU3 in human cancers
    • Miyagi T, Wada T, Yamaguchi K. (2008). Roles of plasma membrane-associated sialidase NEU3 in human cancers. Biochim Biophys Acta 1780: 532-537.
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 532-537
    • Miyagi, T.1    Wada, T.2    Yamaguchi, K.3
  • 24
    • 0027176228 scopus 로고
    • Constitutive activation of Src family kinases in mouse embryos that lack Csk
    • Nada S, Yagi T, Takeda H, Tokunaga T, Nakagawa H, Ikawa Y, et al. (1993). Constitutive activation of Src family kinases in mouse embryos that lack Csk. Cell 73: 1125-1135.
    • (1993) Cell , vol.73 , pp. 1125-1135
    • Nada, S.1    Yagi, T.2    Takeda, H.3    Tokunaga, T.4    Nakagawa, H.5    Ikawa, Y.6
  • 26
    • 43449088823 scopus 로고    scopus 로고
    • The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src
    • Oneyama C, Hikita T, Enya K, Dobenecker MW, Saito K, Nada S, et al. (2008). The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src. Mol Cell 30: 426-436.
    • (2008) Mol Cell , vol.30 , pp. 426-436
    • Oneyama, C.1    Hikita, T.2    Enya, K.3    Dobenecker, M.W.4    Saito, K.5    Nada, S.6
  • 27
    • 35748959029 scopus 로고    scopus 로고
    • Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors
    • Pannequin J, Delaunay N, Buchert M, Surrel F, Bourgaux JF, Ryan J, et al. (2007). Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors. Gastroenterology 133: 1554-1568.
    • (2007) Gastroenterology , vol.133 , pp. 1554-1568
    • Pannequin, J.1    Delaunay, N.2    Buchert, M.3    Surrel, F.4    Bourgaux, J.F.5    Ryan, J.6
  • 28
    • 3242700398 scopus 로고    scopus 로고
    • Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways
    • Read RD, Bach EA, Cagan RL. (2004). Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways. Mol Cell Biol 24: 6676-6689.
    • (2004) Mol Cell Biol , vol.24 , pp. 6676-6689
    • Read, R.D.1    Bach, E.A.2    Cagan, R.L.3
  • 29
    • 0032875098 scopus 로고    scopus 로고
    • Fatty acylation of proteins: New insights into membrane targeting of myristoylated and palmitoylated proteins
    • Resh MD. (1999). Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim Biophys Acta 1451: 1-16.
    • (1999) Biochim Biophys Acta , vol.1451 , pp. 1-16
    • Resh, M.D.1
  • 30
    • 37549052532 scopus 로고    scopus 로고
    • Proteomic identification of ZO-1/2 as a novel scaffold for Src/Csk regulatory circuit
    • Saito K, Enya K, Oneyama C, Hikita T, Okada M. (2008). Proteomic identification of ZO-1/2 as a novel scaffold for Src/Csk regulatory circuit. Biochem Biophys Res Commun 366: 969-975.
    • (2008) Biochem Biophys Res Commun , vol.366 , pp. 969-975
    • Saito, K.1    Enya, K.2    Oneyama, C.3    Hikita, T.4    Okada, M.5
  • 31
    • 0028986116 scopus 로고
    • Pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
    • Schaller MD, Parsons JT. (1995). pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol 15: 2635-2645.
    • (1995) Mol Cell Biol , vol.15 , pp. 2635-2645
    • Schaller, M.D.1    Parsons, J.T.2
  • 32
    • 36148956209 scopus 로고    scopus 로고
    • The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells
    • Sirvent A, Boureux A, Simon V, Leroy C, Roche S. (2007). The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells. Oncogene 26: 7313-7323.
    • (2007) Oncogene , vol.26 , pp. 7313-7323
    • Sirvent, A.1    Boureux, A.2    Simon, V.3    Leroy, C.4    Roche, S.5
  • 34
    • 41449099784 scopus 로고    scopus 로고
    • Regulation of FynT function by dual domain docking on PAG/Cbp
    • Solheim SA, Torgersen KM, Tasken K, Berge T. (2008). Regulation of FynT function by dual domain docking on PAG/Cbp. J Biol Chem 283: 2773-2783.
    • (2008) J Biol Chem , vol.283 , pp. 2773-2783
    • Solheim, S.A.1    Torgersen, K.M.2    Tasken, K.3    Berge, T.4
  • 35
    • 0142092607 scopus 로고    scopus 로고
    • A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila
    • Stewart RA, Li DM, Huang H, Xu T. (2003). A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila. Oncogene 22: 6436-6444.
    • (2003) Oncogene , vol.22 , pp. 6436-6444
    • Stewart, R.A.1    Li, D.M.2    Huang, H.3    Xu, T.4
  • 36
    • 0038386613 scopus 로고    scopus 로고
    • Src family kinases in tumor progression and metastasis
    • Summy JM, Gallick GE. (2003). Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev 22: 337-358.
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 337-358
    • Summy, J.M.1    Gallick, G.E.2
  • 37
    • 16444382989 scopus 로고    scopus 로고
    • ErbB2 promotes Src synthesis and stability: Novel mechanisms of Src activation that confer breast cancer metastasis
    • Tan M, Li P, Klos KS, Lu J, Lan KH, Nagata Y, et al. (2005). ErbB2 promotes Src synthesis and stability: novel mechanisms of Src activation that confer breast cancer metastasis. Cancer Res 65: 1858-1867.
    • (2005) Cancer Res , vol.65 , pp. 1858-1867
    • Tan, M.1    Li, P.2    Klos, K.S.3    Lu, J.4    Lan, K.H.5    Nagata, Y.6
  • 38
    • 41349111083 scopus 로고    scopus 로고
    • Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts
    • Tauzin S, Ding H, Khatib K, Ahmad I, Burdevet D, van Echten-Deckert G, et al. (2008). Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts. Blood 111: 2310-2320.
    • (2008) Blood , vol.111 , pp. 2310-2320
    • Tauzin, S.1    Ding, H.2    Khatib, K.3    Ahmad, I.4    Burdevet, D.5    Van Echten-Deckert, G.6
  • 39
    • 0031439247 scopus 로고    scopus 로고
    • Cellular functions regulated by Src family kinases
    • Thomas SM, Brugge JS. (1997). Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 13: 513-609.
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 513-609
    • Thomas, S.M.1    Brugge, J.S.2
  • 40
    • 33746826012 scopus 로고    scopus 로고
    • Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles
    • Veracini L, Franco M, Boureux A, Simon V, Roche S, Benistant C. (2006). Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles. J Cell Sci 20: 2921-2934.
    • (2006) J Cell Sci , vol.20 , pp. 2921-2934
    • Veracini, L.1    Franco, M.2    Boureux, A.3    Simon, V.4    Roche, S.5    Benistant, C.6
  • 41
    • 49749096806 scopus 로고    scopus 로고
    • The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1
    • Veracini L, Simon V, Richard V, Schraven B, Horejsi V, Roche S, et al. (2008). The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1. J Cell Biol 182: 603-614.
    • (2008) J Cell Biol , vol.182 , pp. 603-614
    • Veracini, L.1    Simon, V.2    Richard, V.3    Schraven, B.4    Horejsi, V.5    Roche, S.6
  • 42
    • 2942618768 scopus 로고    scopus 로고
    • A renaissance for SRC
    • Yeatman TJ. (2004). A renaissance for SRC. Nat Rev Cancer 4: 470-480.
    • (2004) Nat Rev Cancer , vol.4 , pp. 470-480
    • Yeatman, T.J.1
  • 43
    • 10744223870 scopus 로고    scopus 로고
    • Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment
    • Zhang SQ, Yang W, Kontaridis MI, Bivona TG, Wen G, Araki T, et al. (2004). Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment. Mol Cell 13: 341-355.
    • (2004) Mol Cell , vol.13 , pp. 341-355
    • Zhang, S.Q.1    Yang, W.2    Kontaridis, M.I.3    Bivona, T.G.4    Wen, G.5    Araki, T.6
  • 44
    • 33645221824 scopus 로고    scopus 로고
    • Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis
    • Zhao M, Janas JA, Niki M, Pandolfi PP, Van Aelst L. (2006). Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Mol Cell Biol 26: 2479-2489.
    • (2006) Mol Cell Biol , vol.26 , pp. 2479-2489
    • Zhao, M.1    Janas, J.A.2    Niki, M.3    Pandolfi, P.P.4    Van Aelst, L.5
  • 45
    • 40749094921 scopus 로고    scopus 로고
    • Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi
    • Zheng X, Resnick RJ, Shalloway D. (2008). Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi. Int J Cancer 122: 1999-2007.
    • (2008) Int J Cancer , vol.122 , pp. 1999-2007
    • Zheng, X.1    Resnick, R.J.2    Shalloway, D.3
  • 46
    • 41149126804 scopus 로고    scopus 로고
    • Decreased CHK protein levels are associated with Src activation in colon cancer cells
    • Zhu S, Bjorge JD, Cheng HC, Fujita DJ. (2008). Decreased CHK protein levels are associated with Src activation in colon cancer cells. Oncogene 27: 2027-2034.
    • (2008) Oncogene , vol.27 , pp. 2027-2034
    • Zhu, S.1    Bjorge, J.D.2    Cheng, H.C.3    Fujita, D.J.4
  • 47
    • 35948961912 scopus 로고    scopus 로고
    • PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation
    • Zhu S, Bjorge JD, Fujita DJ. (2007). PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation. Cancer Res 67: 10129-10137.
    • (2007) Cancer Res , vol.67 , pp. 10129-10137
    • Zhu, S.1    Bjorge, J.D.2    Fujita, D.J.3


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