Toll like receptor agonists augment HPV 11 E7-specific T cell responses by modulating monocyte-derived dendritic cells

Archives of Dermatological Research

Volumn 302, Issue 1, 2010, Pages 57-65

  Chen, Xian Zhen ^a   Mao, Xiao Hong ^b   Zhu, Ke Jian ^a   Jin, Na ^a   Ye, Jun ^a   Cen, Jian Ping ^a   Zhou, Qiang ^a   Cheng, Hao ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Agonist; Condyloma acuminatum; Dendritic cells; Human papillomavirus; Toll like receptor

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; HLA DR ANTIGEN; IMIQUIMOD; INTERLEUKIN 10; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN E7; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST;

ANTIGEN EXPRESSION; ARTICLE; CELL MATURATION; CONDYLOMA ACUMINATUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG EFFECT; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 11; MONOCYTE DERIVED DENDRITIC CELL; NORMAL HUMAN; PRIORITY JOURNAL; TH1 CELL;

AMINOQUINOLINES; ANTIGEN PRESENTATION; CELL DIFFERENTIATION; CELLS, CULTURED; COLONIC NEOPLASMS; CONDYLOMATA ACUMINATA; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; EPITOPES, T-LYMPHOCYTE; FEMALE; HLA-A ANTIGENS; HUMAN PAPILLOMAVIRUS 11; HUMANS; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MONOCYTES; OLIGONUCLEOTIDES; ONCOGENE PROTEINS, VIRAL; POLY I-C; TH1 CELLS; TOLL-LIKE RECEPTORS; TUMOR VIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS; VIRAL VACCINES;

EID: 77949261625     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-009-0976-0     Document Type: Article

References (41)

1. M Adams L Borysiewicz A Fiander, et al. 2001 Clinical studies of human papilloma vaccines in pre-invasive and invasive cancer Vaccine 19 2549 2556 10.1016/S0264-410X(00)00488-6 1:CAS:528:DC%2BD3MXitVOisbw%3D 11257391 (Pubitemid 32234271)
2. I Arany SK Tyring 1996 Status of local cellular immunity in interferon-responsive and -nonresponsive human papillomavirus-associated lesions Sex Transm Dis 23 475 480 1:STN:280:DyaK2s7gt1Wiug%3D%3D 8946632
3. V Athie-Morales HH Smits DA Cantrell, et al. 2004 Sustained IL-12 signaling is required for Th1 development J Immunol 172 61 69 1:CAS:528:DC%2BD3sXpvFegs7g%3D 14688310
4. SM Barratt-Boyes H Kao OJ Finn 1998 Chimpanzee dendritic cells derived in vitro from blood monocytes and pulsed with antigen elicit specific immune responses in vivo J Immunolther 21 142 148 1:CAS:528:DyaK1cXisFGqs70%3D
5. HJ Bontkes TD de Gruijl AJ van den Muysenberg, et al. 2000 Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes in women with cervical neoplasia Int J Cancer 88 92 98 10.1002/1097-0215(20001001)88:1<92:: AID-IJC15>3.0.CO;2-E 1:STN:280:DC%2BD3cvlvVaktA%3D%3D 10962445 (Pubitemid 30677425)
6. AC Boullart EH Aarntzen P Verdijk, et al. 2008 Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration Cancer Immunol Immunother 57 1589 1597 10.1007/s00262-008-0489-2 1:CAS:528:DC%2BD1cXhtVejsbvE 18322684
7. AG Bowie IR Haga 2005 The role of Toll-like receptors in the host response to viruses Mol Immunol 42 859 867 10.1016/j.molimm.2004.11.007 1:CAS:528:DC%2BD2MXjtFOmsbg%3D 15829275 (Pubitemid 40489009)
8. C Buelens V Verhasselt D De Groote, et al. 1997 Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin-10 Eur J Immunol 27 1848 1852 10.1002/eji.1830270805 1:CAS:528:DyaK2sXltlCisrg%3D 9295017 (Pubitemid 27345996)
9. WF Cheng CF Hung CY Chai, et al. 2001 Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen J Clin Invest 108 669 678 1:CAS:528:DC%2BD3MXmsFKrtLw%3D 11544272
10. EM Coccia M Severa E Giacomini, et al. 2004 Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells Eur J Immunol 34 796 805 10.1002/eji.200324610 1:CAS:528:DC%2BD2cXitlGgt7k%3D 14991609 (Pubitemid 39255927)
11. JP Connor K Ferrer JP Kane, et al. 1999 Evaluation of Langerhans cells in the cervical epithelium of women with cervical intraepithelial neoplasia Gynecol Oncol 75 130 135 10.1006/gyno.1999.5559 1:CAS:528:DyaK1MXmt1WqtLY%3D 10502439 (Pubitemid 29477815)
12. JR Daling NS Weiss TG Hislop, et al. 1987 Sexual practices, sexually transmitted diseases, and the incidence of anal cancer N Engl J Med 317 973 977 1:STN:280:DyaL1c%2FhsVSgtg%3D%3D 2821396
13. M Dauer V Lam H Arnold, et al. 2008 Combined use of toll-like receptor agonists and prostaglandin E (2) in the FastDC model: rapid generation of human monocyte-derived dendritic cells capable of migration and IL-12p70 production J Immunol Methods 337 97 105 10.1016/j.jim.2008.07.003 1:CAS:528: DC%2BD1cXhtVagsL3N 18657542
14. TD De Gruijl HJ Bontkes JMM Walboomers, et al. 1998 Differential T helper cell responses to human papillomavirus type 16 E7 related to viral clearance or persistence in patients with cervical neoplasia: a longitudinal study Cancer Res 58 1700 1706 9563486
15. A Ferrara M Nonn P Sehr, et al. 2003 Dendritic cell-based tumor vaccine for cervical cancer II: results of a clinical pilot study in 15 individual patients J Cancer Res Clin Oncol 129 9 521 530 10.1007/s00432-003-0463-5 1:CAS:528:DC%2BD3sXmvVajsrY%3D 12898233 (Pubitemid 37211193)
16. Frazer IH, Tindle RW, Fernando GJP (1999) Safety and immunogenicity of HPV16 E7/Algammulin. In: Tindle RW et al (eds) Vaccines for human papillomavirus infection and anogenital Disease. RG Landes Company, Austin, pp 91-104
17. M Frisch B Glimelius AJ van den Brule, et al. 1997 Sexually transmitted infection as a cause of anal cancer N Engl J Med 337 1350 1358 10.1056/NEJM199711063371904 1:STN:280:DyaK1c%2FgtVSjtg%3D%3D 9358129 (Pubitemid 27467769)
18. SE Goldstone JM Palefsky MT Winnett, et al. 2002 Activity of HspE7, a novel immunotherapy, in patients with anogenital warts Dis Colon Rectum 45 502 527 10.1007/s10350-004-6229-6 12006932 (Pubitemid 34407728)
19. T Haas F Schmitz A Heit, et al. 2009 Sequence independent interferon-alpha induction by multimerized phosphodiester DNA depends on spatial regulation of Toll-like receptor-9 activation in plasmacytoid dendritic cells Immunology 126 290 298 10.1111/j.1365-2567.2008.02897.x 1:CAS:528: DC%2BD1MXhsVCit74%3D 19019086
20. C Haase TN Jorgensen BK Michelsen 2002 Both exogenous and endogenous interleukin-10 affects the maturation of bone-marrow-derived dendritic cells in vitro and strongly influences T-cell priming in vivo Immunology 107 489 499 10.1046/j.1365-2567.2002.01529.x 1:CAS:528:DC%2BD38Xps1yqtLc%3D 12460194 (Pubitemid 36693654)
21. EA Holly AS Whittemore DA Aston, et al. 1989 Anal cancer incidence: genital warts, anal fissure or fistula, hemorrhoids, and smoking J Natl Cancer Inst 81 1726 1731 10.1093/jnci/81.22.1726 1:STN:280:DyaK3c%2FktVOluw%3D%3D 2810388
22. CF Hung B Ma A Monie, et al. 2008 Therapeutic human papillomavirus vaccines: current clinical trials and future directions Expert Opin Biol Ther 8 421 439 10.1517/14712598.8.4.421 1:CAS:528:DC%2BD1cXjsFWkuro%3D 18352847 (Pubitemid 351570408)
23. K Lore MR Betts JM Brenchley, et al. 2003 Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses J Immunol 171 4320 4328 1:CAS:528:DC%2BD3sXnvVOktL4%3D 14530357
24. M Matsumoto K Funami M Tanabe, et al. 2003 Subcellular localization of Toll-like receptor 3 in human dendritic cells J Immunol 171 3154 3162 1:CAS:528:DC%2BD3sXmvFGqurg%3D 12960343
25. K McKenna AS Beignon N Bhardwaj 2005 Plasmacytoid dendritic cells: linking innate and adaptive immunity J Virol 79 17 27 10.1128/JVI.79.1.17-27. 2005 1:CAS:528:DC%2BD2MXhslensg%3D%3D 15596797 (Pubitemid 39648359)
26. M Melbye TR Cote L Kessler, et al. 1994 High incidence of anal cancer among AIDS patients. The AIDS/Cancer Working Group Lancet 343 636 639 10.1016/S0140-6736(94)92636-0 1:STN:280:DyaK2c7lvVGhsw%3D%3D 7906812 (Pubitemid 24087808)
27. OM Memar I Arany SK Tyring 1995 Skin-associated lymphoid tissue in human immunodeficiency virus-1, human papillomavirus, and herpes simplex virus infections J Invest Dermatol 105 99S 104S 10.1111/1523-1747.ep12316241 1:STN:280:DyaK2MzktFSlsg%3D%3D 7616007
28. AS Morel S Quaratino DC Douek 1997 Split activity of interleukin-10 on antigen capture and antigen presentation by human dendritic cells: definition of a maturative step Eur J Immunol 27 26 34 10.1002/eji.1830270105 1:CAS:528:DyaK2sXptVSmsQ%3D%3D 9021994 (Pubitemid 27046054)
29. F Mota N Rayment S Chong, et al. 1999 The antigen-presenting environment in normal and human papillomavirus (HPV)-related premalignant cervical epithelium Clin Exp Immunol 116 33 40 10.1046/j.1365-2249.1999.00826.x 1:CAS:528:DyaK1MXis1Cnsbc%3D 10209502 (Pubitemid 29170001)
30. F Niedergang A Didierlaurent JP Kraehenbuhl, et al. 2004 Dendritic cells: the host Achille's heel for mucosal pathogens? Trends Microbiol 12 79 88 10.1016/j.tim.2003.12.011 1:CAS:528:DC%2BD2cXpsVOisg%3D%3D 15036324 (Pubitemid 38167342)
31. CN Renn DJ Sanchez MT Ochoa, et al. 2006 TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response J Immunol 177 298 305 1:CAS:528:DC%2BD28XlvV2ntr4%3D 16785525
32. AD Santin S Bellone M Gokden, et al. 2002 Vaccination with HPV-18 E7-pulsed dendritic cells in a patient with metastatic cervical cancer N Engl J Med 346 1752 1753 10.1056/NEJM200205303462219 12037163 (Pubitemid 34547498)
33. AD Santin S Bellone M Palmieri, et al. 2006 HPV16/18 E7-pulsed dendritic cell vaccination in cervical cancer patients with recurrent disease refractory to standard treatment modalities Gynecol Oncol 100 3 469 478 10.1016/j.ygyno.2005.09.040 1:CAS:528:DC%2BD28XhsFKrtrg%3D 16249018 (Pubitemid 43246861)
34. SM Santini C Lapenta L Santodonato 2009 IFN-alpha in the generation of dendritic cells for cancer immunotherapy Handb Exp Pharmacol 188 295 317 10.1007/978-3-540-71029-5-14 1:CAS:528:DC%2BD1MXnvF2ntr8%3D 19031032
35. B Schuler-Thurner ES Schultz TG Berger, et al. 2002 Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells J Exp Med 195 1279 1288 10.1084/jem.20012100 1:CAS:528:DC%2BD38XjvFegt7Y%3D 12021308 (Pubitemid 34564330)
36. M Stanley 2008 HPV vaccines: are they the answer? Br Med Bull 88 59 74 10.1093/bmb/ldn037 18940889
37. MA Tomai SC Gibson LM Imbertson, et al. 1995 Immunomodulating and antiviral activities of the imidazoquinoline S-28463 Antiviral Res 28 253 264 10.1016/0166-3542(95)00054-P 1:CAS:528:DyaK2MXpt1amtL8%3D 8629817
38. SH van der Burg ME Ressing KM Kwappenberg, et al. 2001 Natural T-helper immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: identification of 3 human leukocyte antigen class II-restricted epitopes Int J Cancer 91 612 618 10.1002/1097-0215(200002)9999:9999<::AID-IJC1119>3.0.CO;2-C 11267969 (Pubitemid 32115253)
39. Y Xu KJ Zhu XZ Chen, et al. 2008 Mapping of cytotoxic T lymphocytes epitopes in E7 antigen of human papillomavirus type 11 Arch Dermatol Res 300 235 242 10.1007/s00403-008-0837-2 1:CAS:528:DC%2BD1cXls1Kms70%3D 18299861
40. SJ Youde PR Dunbar EM Evans, et al. 2000 Use of fluorogenic histocompatibility leukocyte antigen-A 0201/HPV 16 E7 peptide complexes to isolate rare human cytotoxic T-lymphocyte-recognizing endogenous human papillomavirus antigens Cancer Res 60 365 371 1:CAS:528:DC%2BD3cXhtVahsLs%3D 10667589
41. KJ Zhao H Cheng KJ Zhu, et al. 2006 Recombined DNA vaccines encoding calreticulin linked to HPV6bE7 enhance immune response and inhibit angiogenic activity in B16 melanoma mouse model expressing HPV 6bE7 antigen Arch Dermatol Res 198 64 72 10.1007/s00403-006-0659-z (Pubitemid 43780145)