Platelet monoamine oxidase activity predicts alcohol sensitivity and voluntary alcohol intake in rhesus monkeys

Upsala Journal of Medical Sciences

Volumn 115, Issue 1, 2010, Pages 49-55

  Wargelius, Hanna Linn ^a   Fahlke, Claudia ^b   Suomi, Stephen J ^c   Oreland, Lars ^a   Higley, James Dee ^d  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c National Institutes   (United States)

^d BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Aggressiveness; Alcohol sensitivity; MAO B; Platelet; Rhesus macaque

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; ALCOHOL; AMINE OXIDASE (FLAVIN CONTAINING);

AGGRESSION; ALCOHOLISM; ANIMAL; ANIMAL BEHAVIOR; ARTICLE; BLOOD; CEREBROSPINAL FLUID; DRINKING BEHAVIOR; FEMALE; MACACA; MALE; RISK FACTOR; STATISTICAL MODEL;

AGGRESSION; ALCOHOL DRINKING; ALCOHOLISM; ANIMALS; BEHAVIOR, ANIMAL; ETHANOL; FEMALE; HYDROXYINDOLEACETIC ACID; MACACA MULATTA; MALE; MODELS, STATISTICAL; MONOAMINE OXIDASE; RISK FACTORS;

EID: 77749280675     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/03009731003605813     Document Type: Article

References (57)

1. Shih JC, Thompson RF. Monoamine oxidase in neuropsychiatry and behavior. Am J Hum Genet. 1999;65:593-598
2. Chen K, Wu HF, Shih JC. The deduced amino acid sequences of human platelet and frontal cortex monoamine oxidase B are identical. J Neurochem. 1993;61:187-190
3. Gottfries CG, Oreland L, Wiberg A, Winblad B. Lowered monoamine oxidase activity in brains from alcoholic suicides. J Neurochem. 1975;25:667-673
4. Buchsbaum MS, Coursey RD, Murphy DL. The biochemical high-risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity. Science. 1976; 194:339-341
5. Wiberg A, Gottfries CG, Oreland L. Low platelet monoamine oxidase activity in human alcoholics.Med Biol. 1977;55:181-186
6. Major LF, Murphy DL. Platelet and plasma amine oxidase activity in alcoholic individuals. Br J Psychiatry. 1978;132: 548-554
7. Cloninger CR, Bohman M, Sigvardsson S. Inheritance of alcohol abuse. Cross-fostering analysis of adopted men. Arch Gen Psychiatry. 1981;38:861-868 (Pubitemid 11040130)
8. Wiberg A, Wahlstroom G, Oreland L. Brain monoamine oxidase activity after chronic ethanol treatment of rats. Psychopharmacology. 1977;52:111-113
9. Oreland L, Wiberg A, Asberg M, Traskman L, Sjostrand L, Thoren P, et al. Platelet MAO activity and monoamine metabolites in cerebrospinal fluid in depressed and suicidal patients and in healthy controls. Psychiatry Res. 1981; 4:21-29
10. von Knorring AL, Oreland L, Häggendal J, Magnusson T, Almay B, Johansson F. Relationship between platelet MAO activity and concentrations of 5-HIAA and HVA in cerebrospinal fluid in chronic pain patients. J Neural Transm. 1986;66:37-46.
11. Fahlke C, Garpenstrand H, Oreland L, Suomi SJ, Higley JD. Platelet monoamine oxidase activity in a nonhuman primate model of type 2 excessive alcohol consumption. Am J Psychiatry. 2002;159:2107.
12. Hariri AR, Holmes A. Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogn Sci. 2006;10:182-191
13. Oreland L. Platelet monoamine oxidase, personality and alcoholism: the rise, fall and resurrection. Neurotoxicology. 2004;25:79-89.
14. Schuckit MA. Low level of response to alcohol as a predictor of future alcoholism. Am J Psychiatry. 1994;151:184-189
15. Schuckit MA. An overview of genetic influences in alcoholism. J Subst Abuse Treat. 2009;36:S5-14.
16. Baldwin HA, Wall TL, Schuckit MA, Koob GF. Differential effects of ethanol on punished responding in the P and NP rats. Alcohol Clin Exp Res. 1991;15:700-704
17. Crabbe JC, Gallaher ES, Phillips TJ, Belknap JK. Genetic determinants of sensitivity to ethanol in inbred mice. Behav Neurosci. 1994;108:186-195
18. Kurtz DL, Stewart RB, Zweifel M, Li TK, Froehlich JC. Genetic differences in tolerance and sensitization to the sedative/hypnotic effects of alcohol. Pharmacol Biochem Behav. 1996;53:585-591
19. Schuckit MA. Biological, psychological and environmental predictors of the alcoholism risk: a longitudinal study. J Stud Alcohol. 1998;59:485-494
20. Heinz A, Higley JD, Gorey JG, Saunders RC, Jones DW, Hommer D, et al. In vivo association between alcohol intoxication, aggression, and serotonin transporter availability in nonhuman primates. Am J Psychiatry. 1998; 155:1023-1028
21. Turker T, Sodmann R, Goebel U, Jatzke S, Knapp M, Lesch KP, et al. High ethanol tolerance in young adults is associated with the low-activity variant of the promoter of the human serotonin transporter gene. Neurosci Lett. 1998; 248:147-150
22. Higley JD, Bennett AJ. Central nervous system serotonin and personality as variables contributing to excessive alcohol consumption in non-human primates. Alcohol Alcohol. 1999;34:402-418
23. Yu PH, Boulton AA. Irreversible inhibition of monoamine oxidase by some components of cigarette smoke. Life Sci. 1987;41:675-682
24. Khalil AA, Davies B, Castagnoli N Jr. Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke. Bioorg Med Chem. 2006; 14:3392-3398
25. Gulliver SB, Rohsenow DJ, Colby SM, Dey AN, Abrams DB, Niaura RS, et al. Interrelationship of smoking and alcohol dependence, use and urges to use. J Stud Alcohol. 1995; 56:202-206
26. Miller NS, Gold MS. Comorbid cigarette and alcohol addiction: epidemiology and treatment. J Addict Dis. 1998; 17:55-66.
27. Daeppen JB, Smith TL, Danko GP, Gordon L, Landi NA, Nurnberger JI Jr, et al. Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women. The Collaborative Study Group on the Genetics of Alcoholism. Alcohol Alcohol. 2000;35:171-175
28. Anthenelli RM, Tipp J, Li TK, Magnes L, Schuckit MA, Rice J, et al. Platelet monoamine oxidase activity in subgroups of alcoholics and controls: results from the Collaborative Study on the Genetics of Alcoholism. Alcohol Clin Exp Res. 1998;22:598-604.
29. Farren CK, Clare AW, Tipton KF, Dinan TG. Platelet MAO activity in subtypes of alcoholics and controls in a homogenous population. J Psychiatr Res. 1998;32:49-54.
30. Garpenstrand H, Longato-Stadler E, af Klinteberg B, Grigorenko E, Damberg M, Oreland L, et al. Low platelet monoamine oxidase activity in Swedish imprisoned criminal offenders. Eur Neuropsychopharmacol. 2002; 12:135-140 (Pubitemid 34168478)
31. Schwandt ML, Higley JD, Suomi SJ, Heilig M, Barr CS. Rapid tolerance and locomotor sensitization in ethanol-naive adolescent rhesus macaques. Alcohol Clin Exp Res. 2008; 32:1217-1228
32. Higley JD, Hasert MF, Suomi SJ, Linnoila M. Nonhuman primate model of alcohol abuse: effects of early experience, personality, and stress on alcohol consumption. Proc Natl Acad Sci U S A. 1991;88:7261-7265
33. Malmberg K, Wargelius HL, Lichtenstein P, Oreland L, Larsson JO. ADHD and Disruptive Behavior scores-associations with MAO-A and 5-HTT genes and with platelet MAO-B activity in adolescents. BMC Psychiatry. 2008; 8:28.
34. Virkkunen M, Linnoila M. Brain serotonin, type II alcoholism and impulsive violence. J Stud Alcohol Suppl. 1993;11:163-169
35. Higley JD, King ST Jr, Hasert MF, Champoux M, Suomi SJ, Linnoila M. Stability of interindividual differences in serotonin function and its relationship to severe aggression and competent social behavior in rhesus macaque females. Neuropsychopharmacology. 1996;14:67-76.
36. Schuckit MA, Smith TL, Kalmijn J. The search for genes contributing to the low level of response to alcohol: patterns of findings across studies. Alcohol Clin Exp Res. 2004;28:1449-1458
37. Limson R, Goldman D, Roy A, Lamparski D, Ravitz B, Adinoff B, et al. Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. Arch Gen Psychiatry. 1991;48:437-441
38. Berman ME, Coccaro EF. Neurobiologic correlates of violence: relevance to criminal responsibility. Behav Sci Law. 1998;16:303-318
39. Pihl RO, LeMarquand D. Serotonin and aggression and the alcohol-aggression relationship. Alcohol Alcohol. 1998;33: 55-65.
40. Bushman BJ, Cooper HM. Effects of alcohol on human aggression: an integrative research review. Psychol Bull. 1990;107:341-354
41. Ito TA, Miller N, Pollock VE. Alcohol and aggression: ametaanalysis on the moderating effects of inhibitory cues, triggering events, and self-focused attention. Psychol Bull. 1996; 120:60-82.
42. Giancola PR, Helton EL, Osborne AB, Terry MK, Fuss AM, Westerfield JA. The effects of alcohol and provocation on aggressive behavior in men and women. J Stud Alcohol. 2002;63:64-73.
43. Miczek KA, DeBold JF, van Erp AM. Neuropharmacological characteristics of individual differences in alcohol effects on aggression in rodents and primates. Behav Pharmacol. 1994;5:407-421
44. Nilsson KW, Sjoberg RL, Wargelius HL, Leppert J, Lindstrom L, Oreland L. The monoamine oxidase A (MAO-A) gene, family function and maltreatment as predictors of destructive behaviour during male adolescent alcohol consumption. Addiction. 2007;102:389-398
45. Saudou F, Amara DA, Dierich A, LeMeur M, Ramboz S, Segu L, et al. Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science. 1994;265:1875-1878
46. Cases O, Seif I, Grimsby J, Gaspar P, Chen K, Pournin S, et al. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science. 1995;268:1763-1766
47. Pihl RO, Young SN, Harden P, Plotnick S, Chamberlain B, Ervin FR. Acute effect of altered tryptophan levels and alcohol on aggression in normal human males. Psychopharmacology (Berl). 1995;119:353-360
48. Popova NK, Naumenko VS, Plyusnina IZ, Kulikov AV. Reduction in 5-HT1A receptor density, 5-HT1A mRNA expression, and functional correlates for 5-HT1A receptors in genetically defined aggressive rats. J Neurosci Res. 2005;80:286-292
49. von Knorring AL, Oreland L, Perris C. Neurophysiological measures and visual averaged evoked responses in psychiatric patients. Relationship to monoamine oxidase activity in platelets. Neuropsychobiology. 1977;3:65-74.
50. Hegerl U, Juckel G. Intensity dependence of auditory evoked potentials as an indicator of central serotonergic neurotransmission: a new hypothesis. Biol Psychiatry. 1993;33:173-187
51. Oxenstierna G, Edman G, Iselius L, Oreland L, Ross SB, Sedvall G. Concentrations of monoamine metabolites in the cerebrospinal fluid of twins and unrelated individuals-a genetic study. J Psychiatr Res. 1986;20:19-29.
52. Pedersen NL, Oreland L, Reynolds C,McClearn GE. Importance of genetic effects for monoamine oxidase activity in thrombocytes in twins reared apart and twins reared together. Psychiatry Res. 1993;46:239-251
53. Winblad B, Gottfries CG, Oreland L, Wiberg A. Monoamine oxidase in platelets and brains of non-psychiatric and non-neurological geriatric patients. Med Biol. 1979;57: 129-132
54. Young WF Jr, Laws ER Jr, Sharbrough FW, Weinshilboum RM. Human monoamine oxidase. Lack of brain and platelet correlation. Arch Gen Psychiatry. 1986;43:604-609
55. Damberg M, Garpenstrand H, Hallman J, Oreland L. Genetic mechanisms of behavior-don't forget about the transcription factors. Mol Psychiatry. 2001;6:503-510
56. Gaspar P, Cases O, Maroteaux L. The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci. 2003;4:1002-1012
57. Eensoo D, Harro M, Pullmann H, Allik J, Harro J. Association of traffic behavior with personality and platelet monoamine oxidase activity in schoolchildren. J Adolesc Health. 2007;40:311-317