Point mutations (Q19P and N23K) increase the operational solubility of a 2α-o-benzoyltransferase that conveys various acyl groups from CoA to a taxane acceptor

Journal of Natural Products

Volumn 73, Issue 2, 2010, Pages 151-159

  Nawarathne, Irosha N ^a   Walker, Kevin D ^b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Michigan State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2ALPHA O BENZOYLTRANSFERASE; BACCATIN III; CARBONYL DERIVATIVE; COENZYME A; COMPLEMENTARY DNA; ESTER DERIVATIVE; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; GENE LOCUS; GENE OVEREXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT GENE; POINT MUTATION; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; SOLUBILITY; TAXUS; TAXUS CUSPIDATA; TRANSPORT KINETICS; WILD TYPE;

ACYLTRANSFERASES; BIOCATALYSIS; BRIDGED COMPOUNDS; MOLECULAR STRUCTURE; POINT MUTATION; TAXOIDS; TAXUS;

TAXUS CUSPIDATA;

EID: 77749271279     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np900524d     Document Type: Article

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