Multimodal nonlinear imaging of the human cornea

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 5, 2010, Pages 2459-2465

  Aptel, Florent ^a,b   Olivier, Nicolas ^c   Deniset Besseau, Ariane ^c   Legeais, Jean Marc ^b   Plamann, Karsten ^a   Schanne Klein, Marie Claire ^c   Beaurepaire, Emmanuel ^c  

^a CNRS   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c LABORATOIRE D OPTIQUE ET BIOSCIENCES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRILLAR COLLAGEN; COLLAGEN;

ANISOTROPY; ARTICLE; CONTROLLED STUDY; CORNEA; CORNEA EDEMA; CORNEA STROMA; HUMAN; HUMAN TISSUE; MICROSCOPY; MULTIPHOTON MICROSCOPY; NONLINEAR SYSTEM; PRIORITY JOURNAL; SECOND HARMONIC GENERATION MICROSCOPY; THIRD HARMONIC GENERATION MICROSCOPY; TRABECULAR MESHWORK; TWO PHOTON EXCITED FLUORESCENCE MICROSCOPY; CORNEA ENDOTHELIUM; CORNEA EPITHELIUM; CYTOLOGY; DONOR; EYEBANK; FLUORESCENCE POLARIZATION; METHODOLOGY; PATHOLOGY; SCLERA;

COLLAGEN; CORNEA; CORNEAL EDEMA; CORNEAL STROMA; ENDOTHELIUM, CORNEAL; EPITHELIUM, CORNEAL; EYE BANKS; FLUORESCENCE POLARIZATION; HUMANS; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; SCLERA; TISSUE DONORS; TRABECULAR MESHWORK;

EID: 77749260080     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4586     Document Type: Article

References (41)

1. Drexler W, Fujimoto JG. State-of-the-art retinal optical coherence tomography. Prog Retin Eye Res. 2008;27:45-88.
2. Jalbert I, Stapleton F, Papas E, Sweeney DF, Coroneo M. In vivo confocal microscopy of the human cornea. Br J Ophthalmol. 2003;87:225-236.
3. Zipfel WR, Williams RM, Webb WW. Nonlinear magic: multiphoton microscopy in the biosciences. Nat Biotechnol. 2003;21: 1369-1377.
4. Zipfel WR, Williams RM, Christie R, Nikitin AY, Hyman BT, Webb WW. Live tissue intrinsic emission microscopy using multiphotonexcited native fluorescence and second harmonic generation. Proc Nat Acad Sci USA. 2003;100:7075-7080.
5. Piston DW, Masters BR, Webb WW. 3-Dimensionally resolved Nad(P)H cellular metabolic redox imaging of the in-situ cornea with 2-photon excitation laser-scanning microscopy. J Microsc. 1995;178:20-27.
6. Lyubovitsky JG, Spencer JA, Krasieva TB, Andersen B, Tromberg BJ. Imaging corneal pathology in a transgenic mouse model using nonlinear microscopy. J Biomed Opt. 2006;11:014013.
7. Teng SW, Tan HY, Peng JL, et al. Multiphoton autofluorescence and second-harmonic generation imaging of the ex vivo porcine eye. Invest Ophthalmol Vis Sci. 2006;47:1216-1224.
8. Wang BG, Koenig K, Riemann I, Krieg R, Halbhuber KJ. Intraocular multiphoton microscopy with subcellular spatial resolution by infrared femtosecond lasers. Histochem Cell Biol. 2006;126:507-515.
9. Campagnola PJ, Millard AC, Terasaki M, Hoppe PE, Malone CJ, Mohler WA. Three-dimensional high-resolution second-harmonic generation imaging of endogenous structural proteins in biological tissues. Biophys J. 2002;82:493-508.
10. Williams RM, Zipfel WR, Webb WW. Interpreting second-harmonic generation images of collagen I fibrils. Biophys J. 2005;88: 1377-1386.
11. Strupler M, Pena AM, Hernest M, et al. Second harmonic imaging and scoring of collagen in fibrotic tissues. Opt Express. 2007;15: 4054-4065.
12. Han X, Burke RM, Zettel ML, Tang P, Brown EB. Second harmonic properties of tumor collagen: determining the structural relationship between reactive stroma and healthy stroma. Opt Express. 2008;16:1846-1859.
13. Yeh AT, Nassif N, Zoumi A, Tromberg BJ. Selective corneal imaging using combined second-harmonic generation and two-photon excited fluorescence. Opt Lett. 2002;27:2082-2084.
14. Han M, Giese G, Bille JF. Second harmonic generation imaging of collagen fibrils in cornea and sclera. Opt Express. 2005;13:5791-5797.
15. Morishige N, Wahlert AJ, Kenney MC, et al. Second-harmonic imaging microscopy of normal human and keratoconus cornea. Invest Ophthalmol Vis Sci. 2007;48:1087-1094.
16. Wu Q, Yeh AT. Rabbit cornea microstructure response to changes in intraocular pressure visualized by using nonlinear optical microscopy. Cornea. 2008;27:202-208.
17. Barad Y, Eisenberg H, Horowitz M, Silberberg Y. Nonlinear scanning laser microscopy by third harmonic generation. Appl Phys Lett. 1997;70:922-924.
18. Muller M, Squier J, Wilson KR, Brakenhoff GJ. 3D microscopy of transparent objects using third-harmonic generation. J Microsc. 1998;191:266-274.
19. Débarre D, Supatto W, Pena AM, et al. Imaging lipid bodies in cells and tissues using third-harmonic generation microscopy. Nat Methods. 2006;3:47-53.
20. Oron D, Yelin D, Tal E, Raz S, Fachima R, Silberberg Y. Depthresolved structural imaging by third-harmonic generation microscopy. J Struct Biol. 2004;147:3-11.
21. Tai SP, Lee WJ, Shieh DB, et al. In vivo optical biopsy of hamster oral cavity with epi-third-harmonic-generation microscopy. Opt Express. 2006;14:6178-6187.
22. Chen SY, Yu HC, Wang IJ, Sun CK. Infrared-based third and second harmonic generation imaging of cornea. J Biomed Opt. 2009;14: 044012.
23. Supatto W, Débarre D, Moulia B, et al. In vivo modulation of morphogenetic movements in Drosophila embryos with femtosecond laser pulses. Proc Nat Acad Sci USA. 2005;102:1047-1052.
24. Oron D, Tal E, Silberberg Y. Depth-resolved multiphoton polarization microscopy by third-harmonic generation. Opt Lett. 2003;28: 2315-2317.
25. Olivier N, Beaurepaire E. Third-harmonic generation microscopy with focus-engineered beams: a numerical study. Opt Express. 2008;16:14703-14715.
26. Débarre D, Beaurepaire E. Quantitative characterization of biological liquids for third-harmonic generation microscopy. Biophys J. 2007;92:603-612.
27. Débarre D, Olivier N, Beaurepaire E. Signal epidetection in thirdharmonic generation microscopy of turbid media. Opt Express. 2007;15:8913-8924.
28. Yu CH, Tai SP, Kung CT, et al. Molecular third-harmonic-generation microscopy through resonance enhancement with absorbing dye. Opt Lett. 2008;33:387-389.
29. Boulesteix T, Pena AM, Pages N, et al. Micrometer scale ex vivo multiphoton imaging of unstained arterial wall structure. Cytometry Part A. 2006;69A:20-26.
30. Meek KM, Tuft SJ, Huang YF, et al. Changes in collagen orientation and distribution in keratoconus corneas. Invest Ophthalmol Vis Sci. 2005;46:1948-1956.
31. Aitken DA, Beirouty ZA, Lee WR. Ultrastructural study of the corneal epithelium in the recurrent erosion syndrome. Br J Ophthalmol. 1995;79:282-289.
32. Moller-Pedersen T, Li HF, Petroll WM, Cavanagh HD, Jester JV. Confocal microscopic characterization of wound repair after photorefractive keratectomy. Invest Ophthalmol Vis Sci. 1998;39: 487-501.
33. Ohno K, Mitooka K, Nelson LR, Hodge DO, Bourne WM. Keratocyte activation and apoptosis in transplanted human corneas in a xenograft model. Invest Ophthalmol Vis Sci. 2002;43:1025-1031.
34. Sonigo B, Iordanidou V, Chong-Sit D, et al. In vivo corneal confocal microscopy comparison of intralase femtosecond laser and mechanical microkeratome for laser in situ keratomileusis. Invest Ophthalmol Vis Sci. 2006;47:2803-2811.
35. Akiba M, Maeda N, Yumikake K, et al. Ultrahigh-resolution imaging of human donor cornea using full-field optical coherence tomography. J Biomed Opt. 2007;12:041202.
36. Edelhauser HF. The balance between corneal transparency and edema: the Proctor Lecture. Invest Ophthalmol Vis Sci. 2006;47: 1755-1767.
37. Farrell RA, McCally RL. Corneal transparency and its loss with swelling. J Opt Soc Am. 1976;66:342-345.
38. Hennighausen H, Feldman ST, Bille JF, McCulloch AD. Anteriorposterior strain variation in normally hydrated and swollen rabbit cornea. Invest Ophthalmol Vis Sci. 1998;39:253-262.
39. Llobet A, Gasull X, Gual A. Understanding trabecular meshwork physiology: a key to the control of intraocular pressure? News Physiol Sci. 2003;18:205-209.
40. Tan JCH, Peters DM, Kaufman PL. Recent developments in understanding the pathophysiology of elevated intraocular pressure. Curr Opin Ophthalmol. 2006;17:168-174.
41. Nuzzo V, Plamann K, Savoldelli M, et al. In situ monitoring of second-harmonic generation in human corneas to compensate for femtosecond laser pulse attenuation in keratoplasty. J Biomed Opt. 2007;12:064032.