메뉴 건너뛰기




Volumn 95, Issue 3, 2010, Pages 1060-1068

Obesity without established comorbidities of the metabolic syndrome is associated with a proinflammatory and prothrombotic state, even before the onset of puberty in children

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; FIBRINOGEN; INTERLEUKIN 6; PLASMINOGEN ACTIVATOR INHIBITOR 1;

EID: 77749240196     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-1887     Document Type: Article
Times cited : (98)

References (46)
  • 4
    • 38149016732 scopus 로고    scopus 로고
    • Metabolic syndrome in childhood predicts adult metabolic syndrome and type 2 diabetes mellitus 25 to 30 years later
    • Morrison JA, Freedman LA, Wang P, Glueck CJ 2008 Metabolic syndrome in childhood predicts adult metabolic syndrome and type 2 diabetes mellitus 25 to 30 years later. J Pediatr 152:201-206
    • (2008) J Pediatr , vol.152 , pp. 201-206
    • Morrison, J.A.1    Freedman, L.A.2    Wang, P.3    Glueck, C.J.4
  • 5
    • 0043240339 scopus 로고    scopus 로고
    • Prevalence of a metabolic syndrome phenotype in adolescents: Findings from the third National Health and Nutrition Examination Survey, 1988-1994
    • Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH 2003 Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Arch Pediatr Adolesc Med 157:821-827
    • (2003) Arch Pediatr Adolesc Med , vol.157 , pp. 821-827
    • Cook, S.1    Weitzman, M.2    Auinger, P.3    Nguyen, M.4    Dietz, W.H.5
  • 9
    • 15944390636 scopus 로고    scopus 로고
    • The metabolic syndrome and concentrations of C-reactive protein among U.S. youth
    • Ford ES, Ajani UA, Mokdad AH 2005 The metabolic syndrome and concentrations of C-reactive protein among U.S. youth. Diabetes Care 28:878-881
    • (2005) Diabetes Care , vol.28 , pp. 878-881
    • Ford, E.S.1    Ajani, U.A.2    Mokdad, A.H.3
  • 11
    • 41849141673 scopus 로고    scopus 로고
    • August GP, Caprio S, Fennoy I, Freemark M, Kaufman FR, Lustig RH, Silverstein JH, Speiser PW, Styne DM, Montori VM; Endocrine Society 2008 Prevention and treatment of pediatric obesity: an endocrine society clinical practice guideline based on expert opinion. J Clin Endocrinol Metab 93:4576-4599
    • August GP, Caprio S, Fennoy I, Freemark M, Kaufman FR, Lustig RH, Silverstein JH, Speiser PW, Styne DM, Montori VM; Endocrine Society 2008 Prevention and treatment of pediatric obesity: an endocrine society clinical practice guideline based on expert opinion. J Clin Endocrinol Metab 93:4576-4599
  • 12
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and international association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith Jr SC 2009 Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and international association for the Study of Obesity. Circulation 120:1640-1645.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3    Zimmet, P.Z.4    Cleeman, J.I.5    Donato, K.A.6    Fruchart, J.C.7    James, W.P.8    Loria, C.M.9    Smith Jr, S.C.10
  • 13
    • 0030681320 scopus 로고    scopus 로고
    • Relation of fasting insulin to blood pressure and lipids in adolescents and parents
    • Sinaiko AR, Gomez-Marin O, Prineas RJ 1997 Relation of fasting insulin to blood pressure and lipids in adolescents and parents. Hypertension 30:1554-1559
    • (1997) Hypertension , vol.30 , pp. 1554-1559
    • Sinaiko, A.R.1    Gomez-Marin, O.2    Prineas, R.J.3
  • 15
    • 0033214107 scopus 로고    scopus 로고
    • Cardiovascular risk factors clustering features of insulin resistance syndrome (syndrome X) in a biracial (black-white) population of children, adolescents, and young adults: The Bogalusa Heart Study
    • Chen W, Srinivasan SR, Elkasabany A, Berenson GS 1999 Cardiovascular risk factors clustering features of insulin resistance syndrome (syndrome X) in a biracial (black-white) population of children, adolescents, and young adults: the Bogalusa Heart Study. Am J Epidemiol 150:667-674
    • (1999) Am J Epidemiol , vol.150 , pp. 667-674
    • Chen, W.1    Srinivasan, S.R.2    Elkasabany, A.3    Berenson, G.S.4
  • 16
    • 0030027671 scopus 로고    scopus 로고
    • Persistent elevation of plasma insulin levels is associated with increased cardiovascular risk in children and young adults. The Bogalusa Heart Study
    • Bao W, Srinivasan SR, Berenson GS 1996 Persistent elevation of plasma insulin levels is associated with increased cardiovascular risk in children and young adults. The Bogalusa Heart Study. Circulation 93:54-59
    • (1996) Circulation , vol.93 , pp. 54-59
    • Bao, W.1    Srinivasan, S.R.2    Berenson, G.S.3
  • 17
    • 33845586264 scopus 로고    scopus 로고
    • Freedman DS, Mei Z, Srinivasan SR, Berenson GS, Dietz WH 2007 Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr 150: 12-17.e2
    • Freedman DS, Mei Z, Srinivasan SR, Berenson GS, Dietz WH 2007 Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr 150: 12-17.e2
  • 18
    • 0032482329 scopus 로고    scopus 로고
    • Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults.NEngl
    • Berenson GS, Sirinivasan SR, Bao W, Newman WP, Tracy 3rd RE, Wattigney WA 1998 Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults.NEngl J Med 338:1650-1656
    • (1998) J Med , vol.338 , pp. 1650-1656
    • Berenson, G.S.1    Sirinivasan, S.R.2    Bao, W.3    Newman, W.P.4    Tracy 3rd, R.E.5    Wattigney, W.A.6
  • 19
    • 0036094537 scopus 로고    scopus 로고
    • Predictability of childhood adiposity and insulin for developing insulin resistance syndrome (syndrome X) in young adulthood: The Bogalusa Heart Study
    • Srinivasan SR, Myers L, Berenson GS 2002 Predictability of childhood adiposity and insulin for developing insulin resistance syndrome (syndrome X) in young adulthood: the Bogalusa Heart Study. Diabetes 51:204-209
    • (2002) Diabetes , vol.51 , pp. 204-209
    • Srinivasan, S.R.1    Myers, L.2    Berenson, G.S.3
  • 20
    • 61349168366 scopus 로고    scopus 로고
    • Progress and challenges in metabolic syndrome in children and adolescents: A scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular Nursing; and Council on Nutrition, Physical Activity, and Metabolism
    • Steinberger J, Daniels SR, Eckel RH, Hayman L, Lustig RH, McCrindle B, Mietus-Snyder ML 2009 Progress and challenges in metabolic syndrome in children and adolescents: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular Nursing; and Council on Nutrition, Physical Activity, and Metabolism. Circulation. 119:628-647
    • (2009) Circulation , vol.119 , pp. 628-647
    • Steinberger, J.1    Daniels, S.R.2    Eckel, R.H.3    Hayman, L.4    Lustig, R.H.5    McCrindle, B.6    Mietus-Snyder, M.L.7
  • 21
    • 69649097826 scopus 로고    scopus 로고
    • Obesity dynamics and cardiovascular risk factor stability in obese adolescents
    • Weiss R, Shaw M, Savoye M, Caprio S 2009 Obesity dynamics and cardiovascular risk factor stability in obese adolescents. Pediatr Diabetes 10:360-367
    • (2009) Pediatr Diabetes , vol.10 , pp. 360-367
    • Weiss, R.1    Shaw, M.2    Savoye, M.3    Caprio, S.4
  • 22
    • 0023644095 scopus 로고
    • Fibrinogen and risk of cardiovascular disease. The Framingham Study
    • Kannel WB, Wolf PA, Castelli WP, D'Agostino RB1987 Fibrinogen and risk of cardiovascular disease. The Framingham Study. JAMA 258:1183-1186
    • (1987) JAMA , vol.258 , pp. 1183-1186
    • Kannel, W.B.1    Wolf, P.A.2    Castelli, W.P.3    D'Agostino, R.B.4
  • 24
    • 0036675410 scopus 로고    scopus 로고
    • Prevalence of insulin resistance syndrome in southwestern France and its relationship with inflammatory and hemostatic markers
    • Marquez-Vidal P, Mazoyer E, Bongard V, Gourdy P, Ruidavets JB, Drouet L, Ferrières J 2002 Prevalence of insulin resistance syndrome in southwestern France and its relationship with inflammatory and hemostatic markers. Diabetes Care 25:1371-1377
    • (2002) Diabetes Care , vol.25 , pp. 1371-1377
    • Marquez-Vidal, P.1    Mazoyer, E.2    Bongard, V.3    Gourdy, P.4    Ruidavets, J.B.5    Drouet, L.6    Ferrières, J.7
  • 25
    • 0027478048 scopus 로고
    • Plasma fibrinogen and its correlates in children from a biracial community: The Bogalusa Heart Study
    • Bao W, Srinivasan SR, Berenson GS 1993 Plasma fibrinogen and its correlates in children from a biracial community: the Bogalusa Heart Study. Pediatr Res 33:323-326
    • (1993) Pediatr Res , vol.33 , pp. 323-326
    • Bao, W.1    Srinivasan, S.R.2    Berenson, G.S.3
  • 27
    • 0033609088 scopus 로고    scopus 로고
    • Evidence for a link between adipose tissue interleukin-6 content and serum C-reactive protein concentrations in obese subjects
    • Bastard JP, Jardel C, Delattre J, Hainque B, Bruckert E, Oberlin F 1999 Evidence for a link between adipose tissue interleukin-6 content and serum C-reactive protein concentrations in obese subjects. Circulation 99:2221-2222
    • (1999) Circulation , vol.99 , pp. 2221-2222
    • Bastard, J.P.1    Jardel, C.2    Delattre, J.3    Hainque, B.4    Bruckert, E.5    Oberlin, F.6
  • 28
    • 0032513756 scopus 로고    scopus 로고
    • Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: Meta-analyses of prospective studies
    • Danesh J, Collins R, Appleby P, Peto R 1998 Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. JAMA 279:1477-1482
    • (1998) JAMA , vol.279 , pp. 1477-1482
    • Danesh, J.1    Collins, R.2    Appleby, P.3    Peto, R.4
  • 29
    • 0033537013 scopus 로고    scopus 로고
    • Elevated C-reactive protein levels in overweight and obese adults
    • Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB 1999 Elevated C-reactive protein levels in overweight and obese adults. JAMA 282:2131-2135
    • (1999) JAMA , vol.282 , pp. 2131-2135
    • Visser, M.1    Bouter, L.M.2    McQuillan, G.M.3    Wener, M.H.4    Harris, T.B.5
  • 30
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?
    • Yudkin JS, Stehouwer CD, Emeis JJ, Coppack SW 1999 C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 19: 972-978
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 972-978
    • Yudkin, J.S.1    Stehouwer, C.D.2    Emeis, J.J.3    Coppack, S.W.4
  • 32
    • 0034511442 scopus 로고    scopus 로고
    • Hypofibrinolysis and increased PAI-1 are linked to atherothrombosis via insulin resistance and obesity
    • Juhan-Vague I, Alessi MC, Morange PE 2000 Hypofibrinolysis and increased PAI-1 are linked to atherothrombosis via insulin resistance and obesity. Ann Med 32(Suppl 1):78-84
    • (2000) Ann Med , vol.32 , Issue.SUPPL. 1 , pp. 78-84
    • Juhan-Vague, I.1    Alessi, M.C.2    Morange, P.E.3
  • 33
    • 0035988198 scopus 로고    scopus 로고
    • The common -675 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is strongly associated with obesity
    • Hoffstedt J, Andersson IL, Persson L, Isaksson B, Arner P 2002 The common -675 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is strongly associated with obesity. Diabetologia 45:584-587
    • (2002) Diabetologia , vol.45 , pp. 584-587
    • Hoffstedt, J.1    Andersson, I.L.2    Persson, L.3    Isaksson, B.4    Arner, P.5
  • 34
    • 0034974761 scopus 로고    scopus 로고
    • Association of angiotensin converting enzyme and plasminogen activator inhibitor-1 promoter gene polymorphisms with features of the insulin resistance syndrome in patients with premature coronary heart disease
    • Viitanen L, Pihlajamäki J, Halonen P, Lehtonen M, Kareinen A, Lehto S, Laakso M 2001 Association of angiotensin converting enzyme and plasminogen activator inhibitor-1 promoter gene polymorphisms with features of the insulin resistance syndrome in patients with premature coronary heart disease. Atherosclerosis 157:57-64
    • (2001) Atherosclerosis , vol.157 , pp. 57-64
    • Viitanen, L.1    Pihlajamäki, J.2    Halonen, P.3    Lehtonen, M.4    Kareinen, A.5    Lehto, S.6    Laakso, M.7
  • 35
    • 14844320865 scopus 로고    scopus 로고
    • Lifestyle-only intervention attenuates the inflammatory state associated with obesity: A randomized controlled study in adolescents
    • Balagopal P, George D, Patton N, Yarandi H, Roberts WL, Bayne E, Gidding S 2005 Lifestyle-only intervention attenuates the inflammatory state associated with obesity: a randomized controlled study in adolescents. J Pediatr 146:342-348
    • (2005) J Pediatr , vol.146 , pp. 342-348
    • Balagopal, P.1    George, D.2    Patton, N.3    Yarandi, H.4    Roberts, W.L.5    Bayne, E.6    Gidding, S.7
  • 37
    • 56749106312 scopus 로고    scopus 로고
    • Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto Jr AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group 2008 Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 359: 2195-2207
    • Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto Jr AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group 2008 Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 359: 2195-2207
  • 38
    • 59649099505 scopus 로고    scopus 로고
    • The clinical utility of high-sensitivity C-reactive protein in cardiovascular disease and the potential implication of JUPITER on current practice guidelines
    • Mora S, Musunuru K, Blumenthal RS 2009 The clinical utility of high-sensitivity C-reactive protein in cardiovascular disease and the potential implication of JUPITER on current practice guidelines. Clin Chem 55:219-228
    • (2009) Clin Chem , vol.55 , pp. 219-228
    • Mora, S.1    Musunuru, K.2    Blumenthal, R.S.3
  • 39
    • 0036087332 scopus 로고    scopus 로고
    • Increased synthesis rate of fibrinogen as a basis for its elevated plasma levels in obese female adolescents
    • Balagopal P, Sweeten S, Mauras N 2002 Increased synthesis rate of fibrinogen as a basis for its elevated plasma levels in obese female adolescents. Am J Physiol Endocrinol Metab 282:E899-E904
    • (2002) Am J Physiol Endocrinol Metab , vol.282
    • Balagopal, P.1    Sweeten, S.2    Mauras, N.3
  • 40
    • 47749097975 scopus 로고    scopus 로고
    • Response of fractional synthesis rate (FSR) of fibrinogen, concentration of D-dimer and fibrinolytic balance to physical activity-based intervention in obese children
    • Balagopal P, George D, Sweeten S, Mann KJ, Yarandi H, Mauras N, Vaughan DE 2008 Response of fractional synthesis rate (FSR) of fibrinogen, concentration of D-dimer and fibrinolytic balance to physical activity-based intervention in obese children. J Thromb Haemost 6:1296-1303
    • (2008) J Thromb Haemost , vol.6 , pp. 1296-1303
    • Balagopal, P.1    George, D.2    Sweeten, S.3    Mann, K.J.4    Yarandi, H.5    Mauras, N.6    Vaughan, D.E.7
  • 42
    • 0031667721 scopus 로고    scopus 로고
    • Risk factors in the progression of atherosclerosis in youth
    • Wissler RW, Strong JP 1998 Risk factors in the progression of atherosclerosis in youth. Am J Path 153:1023-1033
    • (1998) Am J Path , vol.153 , pp. 1023-1033
    • Wissler, R.W.1    Strong, J.P.2
  • 43
    • 36849015926 scopus 로고    scopus 로고
    • Childhood body-mass index and the risk of coronary heart disease in adulthood
    • Baker JL, Olsen LW, Sorensen TI 2007 Childhood body-mass index and the risk of coronary heart disease in adulthood. N Engl J Med 357:2329-2337
    • (2007) N Engl J Med , vol.357 , pp. 2329-2337
    • Baker, J.L.1    Olsen, L.W.2    Sorensen, T.I.3
  • 45
    • 41149151710 scopus 로고    scopus 로고
    • Impaired endothelial and smooth muscle functions and arterial stiffness appear before puberty in obese children and are associated with elevated ambulatory blood pressure
    • Aggoun Y, Farpour-Lambert NJ, Marchand LM, Golay E, Maggio AB, Beghetti M 2008 Impaired endothelial and smooth muscle functions and arterial stiffness appear before puberty in obese children and are associated with elevated ambulatory blood pressure. Eur Heart J 29:792-799
    • (2008) Eur Heart J , vol.29 , pp. 792-799
    • Aggoun, Y.1    Farpour-Lambert, N.J.2    Marchand, L.M.3    Golay, E.4    Maggio, A.B.5    Beghetti, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.