Preoxygenated hemoglobin-based oxygen carrier HBOC-201 annihilates myocardial ischemia during brief coronary artery occlusion in pigs

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 3, 2010, Pages

  Hekkert, Maaike Te Lintel ^a   Dubé, Gregory P ^b   Regar, Evelyn ^a   De Boer, Martine ^a   Vranckx, Pascal ^a,c   Van Der Giessen, Wim J ^a   Serruys, Patrick W ^a   Duncker D, Dirk J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Biopure Corporation   (United States)

^c Department of Cardiac Intensive Care and Interventional Cardiology ^*  (Belgium)

Author keywords

Coronary blood flow; Intracoronary infusion; Left ventricular function; Myocardial metabolism

Indexed keywords

ADENOSINE; INOSINE; OXYGEN; POLYMERIZED HEMOGLOBIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BALLOON CATHETER; BLOOD SAMPLING; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG EFFECT; EX VIVO STUDY; FEMALE; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART STROKE VOLUME; HEART VENTRICLE ARRHYTHMIA; HYPEREMIA; INTRACORONARY INFUSION; MALE; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SWINE; TEMPERATURE;

ANIMALS; BLOOD SUBSTITUTES; CORONARY STENOSIS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMODYNAMICS; HEMOGLOBINS; INFUSIONS, INTRAVENOUS; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; OXYGEN; SWINE; TEMPERATURE; VENTRICULAR FUNCTION, LEFT;

EID: 77749237150     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00667.2009     Document Type: Article

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