Altered Ca2+ handling and myofilament desensitization underlie cardiomyocyte performance in normothermic and hyperthermic heat-acclimated rat hearts

Journal of Applied Physiology

Volumn 103, Issue 1, 2007, Pages 266-275

  Cohen, Omer ^a   Kanana, Hifa ^a   Zoizner, Ronen ^a   Gross, Chaya ^a   Meiri, Uri ^a   Stern, Michael D ^b   Gerstenblith, Gary ^c   Horowitz, Michal ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium transients; Cardiomyocyte contractility; L type calcium channel; Phospholamban; Ryanodine receptors

Indexed keywords

1,4 DIHYDROPYRIDINE RECEPTOR; CALCIUM CHANNEL L TYPE; CALCIUM ION; FURA 2; INDO 1; PHOSPHOLAMBAN; RYANODINE; RYANODINE RECEPTOR; SERINE; THREONINE; ATP2A2 PROTEIN, RAT; CALCIUM; CALCIUM BINDING PROTEIN; MESSENGER RNA; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ISOLATION; CONTROLLED STUDY; CYTOSOL; DESENSITIZATION; FLUORESCENCE; HEART MUSCLE CELL; HEAT; HEAT ACCLIMATIZATION; HYPERTHERMIA; INOTROPISM; ISOLATED HEART; MALE; MYOFILAMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOPLASMIC RETICULUM; WESTERN BLOTTING; ACCLIMATIZATION; ANIMAL; CALCIUM SIGNALING; DISEASE MODEL; ENZYMOLOGY; FEVER; GENETICS; HEART CONTRACTION; HEART RATE; HEART VENTRICLE PRESSURE; HEAT INJURY; KINETICS; METABOLISM; MICROFILAMENT; PATHOPHYSIOLOGY; PHOSPHORYLATION;

ACCLIMATIZATION; ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; DISEASE MODELS, ANIMAL; FEVER; HEART RATE; HEAT; HEAT STRESS DISORDERS; KINETICS; MALE; MICROFILAMENTS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; RATS; RNA, MESSENGER; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; VENTRICULAR PRESSURE;

EID: 34447645852     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01351.2006     Document Type: Article

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