Role of probiotics in pediatric patients with helicobacter pylori infection: A comprehensive review of the literature

Helicobacter

Volumn 15, Issue 2, 2010, Pages 79-87

  Lionetti, Elena ^a   Indrio, Flavia ^b   Pavone, Lorenzo ^a   Borrelli, Giorgia ^b   Cavallo, Luciano ^b   Francavilla, Ruggiero ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

Children; Helicobacter pylori; Probiotics; Therapy

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; MALTODEXTRIN; OMEPRAZOLE; PLACEBO; PROBIOTIC AGENT; TINIDAZOLE;

ANTIBIOTIC RESISTANCE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL STRAIN; CELL ADHESION; CHILD; DYSPEPSIA; EPITHELIUM CELL; ERADICATION THERAPY; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTESTINE FLORA; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS JOHNSONII; LACTOBACILLUS REUTERI; LACTOBACILLUS RHAMNOSUS; LACTOBACILLUS SALIVARIUS; MEDLINE; NONHUMAN; PEDIATRICS; PRIORITY JOURNAL; REINFECTION; REVIEW; STOMACH EPITHELIUM; TREATMENT DURATION; UREA BREATH TEST;

ANTIBIOSIS; BACTERIAL ADHESION; COLONY COUNT, MICROBIAL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; PROBIOTICS; TREATMENT OUTCOME;

HELICOBACTER PYLORI;

EID: 77749233899     PISSN: 10834389     EISSN: 15235378     Source Type: Journal    
DOI: 10.1111/j.1523-5378.2009.00743.x     Document Type: Review

References (82)

1. Daugule I, Rowland M. Helicobacter pylori infection in children. Helicobacter 2008 1 : 41 6.
2. Kivi M, Tindberg Y, Sörberg M, et al. Concordance of Helicobacter pylori strains within families. J Clin Microbiol 2003 41 : 5604 5608.
3. Elitsur Y, Yahav J. Helicobacter pylori infection in pediatrics. Helicobacter 2005 10 (Suppl 1 47 53.
4. Uemura N, Okamoto S, Yamamoto S, et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001 345 : 784 789.
5. Ierardi E, Di Leo A, Barone M, et al. Tumor necrosis factor alpha and apoptosis in Helicobacter pylori related progressive gastric damage: a possible mechanism of immune system involvement in epithelial turnover regulation. Immunopharmacol Immunotoxicol 2003 25 : 203 211.
6. Linsalata M, Russo F, Notarnicola M, Berlocco P, Di Leo A. Polyamine profile in human gastric mucasa infected by Helicobacter pylori. Ital J Gastroenterol Hepatol 1998 30 : 484 489.
7. Oderda G, Shcherbakov P, Bontems P, et al. European Pediatric Task Force on Helicobacter pylori. Results from the pediatric European register for treatment of Helicobacter pylori (PERTH). Helicobacter 2007 12 : 150 156.
8. Malfertheiner P, Megraud F, O'Morain C, et al. Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut 2007 56 : 772 781. (Pubitemid 46854190)
9. Deltenre M, Ntounda R, Jonas C, De Koster E. Eradication of Helicobacter pylori: why does it fail? Ital J Gastroenterol Hepatol 1998 30 (Suppl 3 326 328.
10. Kato S, Konno M, Maisawa S, et al. Results of triple eradication therapy in Japanese children: a retrospective multicenter study. J Gastroenterol 2004 39 : 838 843.
11. Francavilla R, Lionetti E, Castellaneta SP, et al. Improved efficacy of 10-Day sequential treatment for Helicobacter pylori eradication in children: a randomized trial. Gastroenterology 2005 129 : 1414 1419.
12. Hamilton-Miller JM. The role of probiotics in the treatment and prevention of Helicobacter pylori infection. Int J Antimicrob Agents 2003 22 : 360 366.
13. Malfertheiner P, Mégraud F, O'Morain C, et al. European Helicobacter Pylori Study Group (EHPSG). Current concepts in the management of Helicobacter pylori infection - the Maastricht 2-2000 Consensus Report. Aliment Pharmacol Ther 2002 16 : 167 180.
14. FAO/WHO. Report on Joint FAO/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria. 2001 ftp://ftp.fao.org/es/esn/food/probio- report-en.pdf.
15. Gill HS, Guarner F. Probiotics and human health: a clinical perspective. Postgrad Med J 2004 80 : 516 526.
16. Sullivan A, Nord CE. Probiotics and gastrointestinal diseases. J Intern Med 2005 257 : 78 92.
17. Indrio F, Riezzo G, Raimondi F, Bisceglia M, Cavallo L, Francavilla R. The effects of probiotics on feeding tolerance, bowel habits, and gastrointestinal motility in preterm newborns. J Pediatr 2008 152 : 801 806.
18. Fuller R. Probiotics in human medicine. Gut 1991 32 : 439 442.
19. Franceschi F, Cazzato A, Nista EC, et al. Role of probiotics in patients with Helicobacter pylori infection. Helicobacter 2007 12 : 59 63.
20. Lorca GL, Wadström T, Valdez GF, Ljungh A. Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro. Curr Microbiol 2001 42 : 39 44.
21. Bhatia SJ, Kochar N, Abraham P, Nair NG, Mehta AP. Lactobacillus acidophilus inhibits growth of Campylobacter pylori in vitro. J Clin Microbiol 1989 27 : 2328 2330.
22. Coconnier MH, Lievin V, Hemery E, Servin AL. Antagonistic activity against Helicobacter infection in vitro and in vivo by the human Lactobacillus acidophilus strain LB. Appl Environ Microbiol 1998 64 : 4573 4580.
23. Rasic J, Klem I, Jovanic D, Ac M. Antimicrobial effect of Lactobacillus acidophilus and Lactobacillus delbrueckii subsp. bulgaricus against Helicobacter pylori in vitro. Arch Gastroenterohepatol 1995 14 : 158 160.
24. Midolo PD, Lambert JR, Hull R, Luo F, Grayson ML. In vitro inhibition of Helicobacter pylori NCTC 11637 by organic acids and lactic acid bacteria. J Appl Bacteriol 1995 79 : 475 479.
25. Michetti P, Dorta G, Wiesel PH, et al. Effect of whey-based culture supernatant of Lactobacillus acidophilus (johnsonii) La1 on Helicobacter pylori infection in humans. Digestion 1999 60 : 203 209.
26. Aiba Y, Suzuki N, Kabir AM, Takagi A, Koga Y. Lactic acid-mediated suppression of Helicobacter pylori by the oral administration of Lactobacillus salivarius as a probiotic in a gnotobiotic murine model. Am J Gastroenterol 1998 93 : 2097 2101.
27. Borruel N, Casellas F, Antolín M, et al. Effects of nonpathogenic bacteria on cytokine secretion by human intestinal mucosa. Am J Gastroenterol 2003 98 : 865 870.
28. Lesbros-Pantoflickova D, Corthésy-Theulaz I, Blum AL. Helicobacter pylori and probiotics. J Nutr 2007 137 (Suppl 2 812 818.
29. Takahashi T, Matsumoto T, Nakamura M, Matsui H, Tsuchimoto K, Yamada H. L-lactic acid secreted from gastric mucosal cells enhances growth of Helicobacter pylori. Helicobacter 2007 12 : 532 540.
30. Johnson C, Dicksved J, Jonsson H, Roos S. Anti Helicobacter pylori activity among lactic acid bacteria isolated from gastric biopsies and strains of Lactobacillus reuteri (abstract). Helicobacter 2003 8 : 473.
31. Pinchuk IV, Bressollier P, Verneuil B, et al. In vitro anti-Helicobacter pylori activity of the probiotic strain Bacillus subtilis 3 is due to secretion of antibiotics. Antimicrob Agents Chemother 2001 45 : 3156 3161.
32. Cats A, Kuipers EJ, Bosschaert MA, Pot RG, Vandenbroucke-Grauls CM, Kusters JG. Effect of frequent consumption of a Lactobacillus casei-containing milk drink in Helicobacter pylori-colonized subjects. Aliment Pharmacol Ther 2003 17 : 429 435.
33. Mukai T, Asasaka T, Sato E, Mori K, Matsumoto M, Ohori H. Inhibition of binding of Helicobacter pylori to the glycolipid receptors by probiotic Lactobacillus reuteri. FEMS Immunol Med Microbiol 2002 32 : 105 110.
34. Nam H, Ha M, Bae O, Lee Y. Effect of Weissella confusa strain PL9001 on the adherence and growth of Helicobacter pylori. Appl Environ Microbiol 2002 68 : 4642 4645. (Pubitemid 34988151)
35. Gerhard M, Hirmo S, Wadstrom T. Helicobacter pylori, an adherent pain in the stomach. In Achtman M, Suerbaum S, eds. Helicobacter pylori: Molecular and Cellular Biology 2001 Wymondham. United Kingdom : Horizon Scientific Press, 2001 185 206.
36. Guruge JL, Falk PG, Lorenz RG, et al. Epithelial attachment alters the outcome of Helicobacter pylori infection. Proc Natl Acad Sci U S A 1998 95 : 3925 3930.
37. Felley C, Michetti P. Probiotics and Helicobacter pylori. Best Pract Res Clin Gastroenterol 2003 17 : 785 791.
38. Magistà AM, Ierardi E, Castellaneta S, et al. Helicobacter pylori status and symptom assessment two years after eradication in pediatric patients from a high prevalence area. J Pediatr Gastroenterol Nutr 2005 40 : 312 318.
39. Byrd JC, Yunker CK, Xu QS, Sternberg LR, Bresalier RS. Inhibition of gastric mucin synthesis by Helicobacter pylori. Gastroenterology 2000 118 : 1072 1079.
40. Mack DR, Michail S, Wei S, McDougall L, Hollingsworth MA. Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression. Am J Physiol 1999 276 : 941 950.
41. Mack DR, Ahrne S, Hyde L, Wei S, Hollingsworth MA. Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro. Gut 2003 52 : 827 833.
42. Pantoflickova D, Corthesy-Theulaz I, Dorta G, et al. Favorable effect of long-term intake of fermented milk containing Lactobacillus johnsonii on Helicobacter pylori associated gastritis. Aliment Pharmacol Ther 2003 18 : 805 813.
43. Noach LA, Bosma NB, Jansen J, Hoek FJ, van Deventer SJ, Tytgat GN. Mucosal tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 production in patients with Helicobacter pylori infection. Scand J Gastroenterol 1994 29 : 425 429.
44. Vitini E, Alvarez S, Medina M, Medici M, de Budeguer MV, Perdigon G. Gut mucosal immunostimulation by lactic acid bacteria. Biocell 2000 24 : 223 232.
45. Myllyluoma E, Kajander K, Mikkola H, et al. Probiotic intervention decreases serum gastrin-17 in Helicobacter pylori infection. Dig Liver Dis 2007 39 : 516 523.
46. Lin YP, Thibodeaux CH, Penã JA, Ferry GD, Versalovic J. Probiotic Lactobacillus reuteri suppress proinflammatory cytokines via c-Jun. Inflamm Bowel Dis 2008 14 : 1068 1083.
47. Iyer C, Kosters A, Sethi G, Kunnumakkara AB, Aggarwal BB, Versalovic J. Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-kappaB and MAPK signalling. Cell Microbiol 2008 10 : 1442 1452.
48. Jones SE, Versalovic J. Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors. BMC Microbiol 2009 9 : 35.
49. Felley CP, Corthésy-Theulaz I, Rivero JL, et al. Favourable effect of an acidified milk (LC-1) on Helicobacter pylori gastritis in man. Eur J Gastroenterol Hepatol 2001 13 : 25 9.
50. Wang KY, Li SN, Liu CS, et al. Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori. Am J Clin Nutr 2004 80 : 737 741.
51. Chang MC, Chang YT, Sun CT, Wu MS, Wang HP, Lin JT. Quantitative correlation of Helicobacter pylori stool antigen (HpSA) test with 13C-urea breath test (13C-UBT) by the updated Sydney grading system of gastritis. Hepatogastroenterology 2002 49 : 576 579.
52. Gotteland M, Cruchet S. Suppressive effect of frequent ingestion of Lactobacillus johnsonii La1 on Helicobacter pylori colonization in asymptomatic volunteers. J Antimicrob Chemother 2003 51 : 1317 1319. (Pubitemid 36622096)
53. Linsalata M, Russo F, Berloco P, et al. The influence of Lactobacillus brevis on ornithine decarboxylase activity and polyamine profiles in Helicobacter pylori-infected gastric mucosa. Helicobacter 2004 9 : 165 172.
54. Sakamoto I, Igarashi M, Kimura K, Takagi A, Miwa T, Koga Y. Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. J Antimicrob Chemother 2001 47 : 709 710.
55. Miki K, Urita Y, Ishikawa F, et al. Effect of Bifidobacterium bifidum fermented milk on Helicobacter pylori and serum pepsinogen levels in humans. J Dairy Sci 2007 90 : 2630 2640.
56. Francavilla R, Lionetti E, Castellaneta SP, et al. Inhibition of Helicobacter pylori infection in humans by Lactobacillus reuteri ATCC 55730 and effect on eradication therapy: a pilot study. Helicobacter 2008 13 : 127 134.
57. Cruchet S, Obregon MC, Salazar G, Diaz E, Gotteland M. Effect of the ingestion of a dietary product containing Lactobacillus johnsonii La1 on Helicobacter pylori colonization in children. Nutrition 2003 19 : 716 721. (Pubitemid 36961381)
58. Gotteland M, Poliak L, Cruchet S, Brunser O. Effect of regular ingestion of Saccharomyces boulardii plus inulin or Lactobacillus acidophilus LB in children colonized by Helicobacter pylori. Acta Paediatr 2005 94 : 1747.
59. Gotteland M, Andrews M, Toledo M, et al. Modulation of Helicobacter pylori colonization with cranberry juice and Lactobacillus johnsonii La1 in children. Nutrition 2008 24 : 421 426.
60. Canducci F, Armuzzi A, Cremonini F, et al. A lyophilized and inactivated culture of Lactobacillus acidophilus increases Helicobacter pylori eradication rates. Aliment Pharmacol Ther 2000 14 : 1625 1629.
61. Armuzzi A, Cremonini F, Bartolozzi F, et al. The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther 2001 15 : 163 169. (Pubitemid 32142492)
62. Armuzzi A, Cremonini F, Ojetti V, et al. Effect of Lactobacillus GG supplementation on antibiotic-associated gastrointestinal side effects during Helicobacter pylori eradication therapy: a pilot study. Digestion 2001 63 : 1 7. (Pubitemid 32098452)
63. Cremonini F, Di Caro S, Covino M, et al. Effect of different probiotic preparations on anti-Helicobacter pylori therapyrelated side effects: a parallel group, triple blind, placebo-controlled study. Am J Gastroenterol 2002 97 : 2744 2749.
64. Sheu B, Wu J, Lo C, et al. Impact of supplement with Lactobacillus- and Bifidobacterium-containing yogurt on triple therapy for Helicobacter pylori eradication. Aliment Pharmacol Ther 2002 16 : 1669 1675. (Pubitemid 35052744)
65. Guo JB, Yang PF, Wang MT. The application of clostridium to the eradication of Helicobacter pylori. Chin J Celiopathy 2004 4 : 163 165.
66. Nista EC, Candelli M, Cremonini F, et al. Bacillus clausii therapy to reduce side-effects of anti-Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial. Aliment Pharmacol Ther 2004 20 : 1181 1188.
67. Cao YJ, Qu CM, Yuan Q, et al. Control of intestinal flora alteration induced by eradication therapy of Helicobacter pylori infection in the elders. Chin J Gastroenterol Hepatol 2005 14 : 195 199.
68. Myllyluoma E, Veijola L, Ahlroos T, et al. Probiotic supplementation improves tolerance to Helicobacter pylori eradication therapy-a placebo-controlled, double-blind, randomized pilot study. Aliment Pharmacol Ther 2005 21 : 1263 1272.
69. Tursi A, Brandimarte G, Giorgetti GM, Modeo ME. Effect of Lactobacillus casei supplementation on the effectiveness and tolerability of a new second-line 10-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection. Med Sci Monit 2005 10 : 662 666.
70. Sykora J, Valeckova K, Amlerova J, et al. Effects of a specially designed fermented milk product containing probiotic Lactobacillus casei DN-114 001 and the eradication of Helicobacter pylori in children: a prospective randomized, double-blind study. J Clin Gastroenterol 2005 39 : 692 698.
71. Goldman CG, Barrado DA, Balcarce N, et al. Effect of a probiotic food as an adjuvant to triple therapy for eradication of Helicobacter pylori infection in children. Nutrition 2006 22 : 984 988.
72. Lionetti E, Miniello VL, Castellaneta SP, et al. Lactobacillus reuteri therapy to reduce side-effects during anti-Helicobacter pylori treatment in children: a randomized placebo controlled trial. Aliment Pharmacol Ther 2006 24 : 1461 1468.
73. Cindoruk M, Erkan G, Karakan T, Dursun A, Unal S. Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study. Helicobacter 2007 12 : 309 316.
74. Park SK, Park DI, Choi JS, et al. The effect of probiotics on Helicobacter pylori eradication. Hepatogastroenterology 2007 54 : 2032 2036.
75. Kim MN, Kim N, Lee SH, et al. The effects of probiotics on PPI-triple therapy for Helicobacter pylori eradication. Helicobacter 2008 13 : 261 268.
76. Hurduc V, Plesca D, Dragomir D, Sajin M, Vandenplas Y. A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children. Acta Paediatr 2009 98 : 127 131.
77. Szajewska H, Albrecht P, Topczewska-Cabanek A. Randomized, double-blind, placebo-controlled trial: effect of lactobacillus GG supplementation on Helicobacter pylori eradication rates and side effects during treatment in children. J Pediatr Gastroenterol Nutr 2009 48 : 431 436.
78. De Bortoli N, Leonardi G, Ciancia E, et al. Helicobacter pylori eradication: a randomized prospective study of triple therapy versus triple therapy plus lactoferrin and probiotics. Am J Gastroenterol 2007 102 : 951 956.
79. Duman DG, Ozdemir F, Birben E, et al. Efficacy and safety of Saccharomyces boulardii in prevention of antibioticassociated diarrhea due to Helicobacter pylori eradication. Eur J Gastroenterol Hepatol 2005 17 : 1357 1361.
80. Imase K, Takahashi M, Tanaka A, et al. Efficacy of Clostridium butyricum preparation concomitantly with Helicobacter pylori eradication therapy in relation to changes in the intestinal microbiota. Microbiol Immunol 2008 52 : 156 161.
81. Plummer SF, Garaiova I, Sarvotham T, et al. Effects of probiotics on the composition of the intestinal microbiota following antibiotic therapy. Int J Antimicrob Agents 2005 26 : 69 74.
82. Yamaoka Y, Kodama T, Kita M, Imanishi J, Kashima K, Graham DY. Relation between clinical presentation, Helicobacter pylori density, interleukin 1beta and 8 production, and cagA status. Gut 1999 45 : 804 811.