Relation between clinical presentation, Helicobacter pylori density, interleukin 1β and 8 production, and cagA status

Gut

Volumn 45, Issue 6, 1999, Pages 804-811

  Yamaoka, Y ^a,c   Kodama, T ^b   Kita, M ^b   Imanishi, J ^b   Kashima, K ^b   Graham, D Y ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

CagA; Duodenal ulcer; Helicobacter pylori; Interleukin 1 ; Interleukin 8

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 8; OUTER MEMBRANE PROTEIN;

ADULT; ARTICLE; BACTERIAL COUNT; BACTERIAL VIRULENCE; CANCER CELL; CLINICAL FEATURE; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DUODENUM ULCER; FEMALE; GASTRITIS; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH ANTRUM; STOMACH BIOPSY;

EID: 0032730542     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.45.6.804     Document Type: Article

References (28)

1. Censini S, Lange C, Xiang Z, et al. cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci 1996;93:14648-53.
2. Sharma SA, Tummuru MK, Miller GG, et al. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect Immun 1995;63:1681-7.
3. Crabtree JE, Xiang Z, Lindley IJD, et al. Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. J Clin Pathol 1995;48:967-9.
4. Atherton JC, Tham KT, Peek RM, et al. Density of Helicobacter pylori infection in vivo as assessed by quantitative culture and histology. J Infect Dis 1996;174:552-6.
5. Yamaoka Y, Kita M, Kodama T, et al. Induction of various cytokines and development of severe mucosal inflammation by cagA gene-positive Helicobacter pylori strains. Gut 1997;41:442-51.
6. Yamaoka Y, Kita M, Kodama T, et al. Chemokines in the gastric mucosa in Helicobacter pylori infection. Gut 1998;42:609-17.
7. Yamaoka Y, Kita M, Kodama T, et al. Helicobacter pylori cagA gene and expression of cytokine messenger RNA in gastric mucosa. Gastroenterology 1996;110:1744-52.
8. Yamaoka Y, Kodama T, Kashima K, et al. Variants of the 3′ region of the cagA gene in Helicobacter pylori isolates from different H pylori associated diseases. J Clin Microbiol 1998;36:2258-63.
9. Atherton JC, Cao P, Peek RM, et al. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. J Biol Chem 1995;270:17771-7.
10. Atherton JC, Twells RJ, Hawkey CJ, et al. New, internationally applicable, polymerase chain reaction-based typing of Helicobacter pylori vacA [abstract]. Gastroenterology 1997;112:A61.
11. Yamaoka Y, Kodama T, M Kita, et al. vacA genotypes of Helicobacter pylori in relation to cagA status, cytotoxin production, or clinical outcome. Helicobacter 1998;3:241-53.
12. Tummuru MK, Sharma A, Blaser MJ. Helicobacter pylori picB, a homologue of the Bordetella pertussis toxin secretion protein, is required for induction of IL-8 in gastric epithelial cells. Mol Microbiol 1995;18:867-76.
13. El-Zimaity HMT, Graham DY, Al-Assi MT, et al. Interobserver variation in the histopathological assessment of Helicobacter pylori gastritis. Hum Pathol 1996;27:35-41.
14. Khulusi S, Mendall MA, Patel P, et al. Helicobacter pylori infection density and gastric inflammation in duodenal ulcer and non-ulcer subjects. Gut 1995;37:319-24.
15. Warburton VJ, Everett S, Mapstone NP, et al. Clinical and histological associations of cagA and vacA genotypes in Helicobacter pylori gastritis. J Clin Pathol 1998;51:55-61.
16. Uemura N, Oomoto Y, Mukui T, et al. Gastric corpus IL-8 concentration and neutrophil infiltration in duodenal ulcer patients. Alimem Pharmacol Ther 1997;11:793-800.
17. Graham DY. Campylobacter pylori and peptic ulcer disease. Gastroenterology 1989;96:615-25.
18. Graham DY. Helicobacter pylori infection in the pathogenesis of duodenal ulcer and gastric cancer: a model. Gastroenterology 1997;113:1983-91.
19. Graham DY, Yamaoka Y. H pylori and cagA: relationships with gastric cancer, duodenal ulcer, and reflux esophagitis and its complications. Helicobacter 1998;3:145-51.
20. Maeda S, Yoshida H, Ikenoue T, et al. Structure of cag pathogenicity island in Japanese Helicobacter pylori isolates. Gut 1999;44:336-41.
21. Kondo S, Shinomura Y, Kanayama S, et al. Helicobacter pylori increases gene expression of hepatocyte growth factor in human gastric mucosa. Biochem Biophys Res Commun 1995;210:960-5.
22. Tunio AM, Holton J, Hobsley M. Gastric juice epidermal growth factor concentration and Helicobacter pylori in patients with duodenal ulcer. Br J Surg 1995;82:1204-6.
23. Yasunaga Y, Shinomura Y, Kanayama S, et al. Mucosal interleukin-1 beta production and acid secretion in enlarged fold gastritis. Alimem Pharmacol Ther 1997;11:801-9.
24. Esplugues JV, Martinez-Cuesta MA, Barrachina MD, et al. Involvement of endogenous nitric oxide in the inhibition by endotoxin and interleukin-1 beta of gastric acid secretion. J Gastroenterol Hepatol 1994;9(Suppl. I):S45-9.
25. Kondo S, Shinomura Y, Kanayama S, et al. Interleukin-1 beta inhibits gastric histamine secretion and synthesis in the rat. Am J Physiol 1994;267:G966-71.
26. Yamaoka Y, Kodama T, Graham DY, et al. Search for putative virulence factors of Helicobacter pylori: The low molecular weight (33-35K) antigen. Dig Dis Sci 1998;43:1482-7.
27. Peek RM, Thompson SA, Donahue JP, et al. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc Assoc Am Physicians 1998;110:531-44.
28. Yamaoka Y, Kwon DH, Graham DY et al. Relationship between outer membrane proteins and interleukin 8 production [abstract]. Gastroenterology 1999;116:A361.