Levamisole and ryanodine receptors (II): An electrophysiological study in Ascaris suum

Molecular and Biochemical Parasitology

Volumn 171, Issue 1, 2010, Pages 8-16

  Puttachary, Sreekanth ^a   Robertson, Alan P ^a   Clark, Cheryl L ^a   Martin, Richard J ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

AF2; Ascaris suum; Caffeine; Electrophysiology; Levamisole; Ryanodine

Indexed keywords

ANION CHANNEL; CALCIUM ION; CHLORIDE ION; CHOLINERGIC RECEPTOR; LEVAMISOLE; MECAMYLAMINE; NEUROPEPTIDE; PROTEIN AF2; RYANODINE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; ASCARIS SUUM; CONTROLLED STUDY; EXPERIMENTAL DESIGN; EXTRACELLULAR CALCIUM; MEMBRANE DEPOLARIZATION; MEMBRANE ELECTROPHYSIOLOGY; MUSCLE ACTION POTENTIAL; MUSCLE CONTRACTION; MUSCLE FLAP; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RESPONSE TIME; STIMULUS RESPONSE;

ANIMALS; ANTHELMINTICS; ASCARIS SUUM; CAFFEINE; CALCIUM; CHLORIDES; CHOLINERGIC AGONISTS; ELECTROPHYSIOLOGICAL PHENOMENA; FURYLFURAMIDE; LEVAMISOLE; MECAMYLAMINE; MODELS, BIOLOGICAL; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

ASCARIS SUUM;

EID: 77649340322     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2009.12.006     Document Type: Article

References (47)

1. Trailovic S.M., Clark C.L., Robertson A.P., and Martin R.J. Brief application of AF2 produces long lasting potentiation of nAChR responses in Ascaris suum. Mol Biochem Parasitol 139 (2005) 51-64
2. Albonico M., Engels D., and Savioli L. Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control. Int J Parasitol 34 (2004) 1205-1210
3. Albonico M., Wright V., Ramsan M., et al. Development of the egg hatch assay for detection of anthelmintic resistance in human hookworms. Int J Parasitol 35 (2005) 803-811
4. Jackson F. Anthelmintic resistance-the state of play. Br Vet J 149 (1993) 123-138
5. Kaplan R.M. Drug resistance in nematodes of veterinary importance: a status report. Trends Parasitol 20 (2004) 477-481
6. Jones P.M., and George A.M. Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling. Int J Parasitol 35 (2005) 555-566
7. Robertson S.J., and Martin R.J. Levamisole-activated single-channel currents from muscle of the nematode parasite Ascaris suum. Br J Pharmacol 108 (1993) 170-178
8. Dale V.M., and Martin R.J. Oxantel-activated single channel currents in the muscle membrane of Ascaris suum. Parasitology 110 (1995) 437-448
9. Evans A.M., and Martin R.J. Activation and cooperative multi-ion block of single nicotinic-acetylcholine channel currents of Ascaris muscle by the tetrahydropyrimidine anthelmintic, morantel. Br J Pharmacol 118 (1996) 1127-1140
10. Robertson A.P., Bjorn H.E., and Martin R.J. Pyrantel resistance alters nematode nicotinic acetylcholine receptor single-channel properties. Eur J Pharmacol 394 (2000) 1-8
11. Levandoski M.M., Robertson A.P., Kuiper S., Qian H., and Martin R.J. Single-channel properties of N- and L-subtypes of acetylcholine receptor in Ascaris suum. Int J Parasitol 35 (2005) 925-934
12. Martin R.J., Clark C.L., Trailovic S.M., and Robertson A.P. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. Int J Parasitol 34 (2004) 1083-1090
13. Hotez P.J., Bethony J., Bottazzi M.E., Brooker S., and Buss P. Hookworm: "the great infection of mankind". PLoS Med 2 (2005) e67
14. Qian H., Martin R.J., and Robertson A.P. Pharmacology of N-, L-, and B-subtypes of nematode nAChR resolved at the single-channel level in Ascaris suum. FASEB J 20 (2006) 2606-2608
15. Robertson A.P., Bjorn H.E., and Martin R.J. Resistance to levamisole resolved at the single-channel level. FASEB J 13 (1999) 749-760
16. Robertson S.J., Pennington A.J., Evans A.M., and Martin R.J. The action of pyrantel as an agonist and an open channel blocker at acetylcholine receptors in isolated Ascaris suum muscle vesicles. Eur J Pharmacol 271 (1994) 273-282
17. Brading A.F., and Caldwell P.C. The resting membrane potential of the somatic muscle cells of Ascaris lumbricoides. J Physiol 217 (1971) 605-624
18. Martin R.J., Verma S., Levandoski M., et al. Drug resistance and neurotransmitter receptors of nematodes: recent studies on the mode of action of levamisole. Parasitology 131 (2005) S71-84
19. Verma S., Robertson A.P., and Martin R.J. The nematode neuropeptide, AF2 (KHEYLRF-NH2), increases voltage-activated calcium currents in Ascaris suum muscle. Br J Pharmacol 151 (2007) 888-899
20. Martin R.J., Thorn P., Gration K.A., and Harrow I.D. Voltage-activated currents in somatic muscle of the nematode parasite Ascaris suum. J Exp Biol 173 (1992) 75-90
21. Thorn P., and Martin R.J. A high-conductance calcium-dependent chloride channel in Ascaris suum muscle. Q J Exp Physiol 72 (1987) 31-49
22. Aoki S., and Ito K. Time- and use-dependent inhibition by ryanodine of caffeine-induced contraction of guinea-pig aortic smooth muscle. Biochem Biophys Res Commun 154 (1988) 219-226
23. Ito K., Ikemoto T., Aoki S., and Ota M. Effects of ryanodine and 9,21-didehydroryanodine on caffeine-induced contraction of rat and guinea pig aortae. Jpn J Pharmacol 51 (1989) 531-538
24. 2+ release. Trends Pharmacol Sci 16 (1995) 386-391
25. 3H]ryanodine and form a large conductance channel. Biophys J 63 (1992) 1379-1384
26. Sakube Y., Ando H., and Kagawa H. Cloning and mapping of a ryanodine receptor homolog gene of Caenorhabditis elegans. Ann NY Acad Sci 707 (1993) 540-545
27. Maryon E.B., Coronado R., and Anderson P. unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction. J Cell Biol 134 (1996) 885-893
28. Turner R.E. A model for an Ascaris muscle cell. Exp Physiol 86 (2001) 551-559
29. Kubiak T.M., Larsen M.J., Davis J.P., Zantello M.R., and Bowman J.W. AF2 interaction with Ascaris suum body wall muscle membranes involves G-protein activation. Biochem Biophys Res Commun 301 (2003) 456-459
30. Komuniecki R., Campbell T., and Rubin N. Anaerobic metabolism in Ascaris suum: acyl CoA intermediates in isolated mitochondria synthesizing 2-methyl branched-chain fatty acids. Mol Biochem Parasitol 24 (1987) 147-154
31. Valkanov M.A., and Martin R.J. A Cl channel in Ascaris suum selectivity conducts dicarboxylic anion product of glucose fermentation and suggests a role in removal of waste organic anions. J Membr Biol 148 (1995) 41-49
32. 2+ exchange interactions: physiopathological implications. Ann NY Acad Sci 1099 (2007) 135-151
33. Reinitz C.A., Herfel H.G., Messinger L.A., and Stretton A.O. Changes in locomotory behavior and cAMP produced in Ascaris suum by neuropeptides from Ascaris suum or Caenorhabditis elegans. Mol Biochem Parasitol 111 1 (2000) 185-197
34. Bennett D.L., Cheek T.R., Berridge M.J., et al. Expression and function of ryanodine receptors in nonexcitable cells. J Biol Chem 271 (1996) 6356-6362
35. 2+ stores in cultured guinea pig myenteric neurons. Am J Physiol 270 (1996) 594-603
36. Fabiato A., and Fabiato F. Calcium release from the sarcoplasmic reticulum. Circ Res 40 (1977) 119-129
37. Rios E., and Pizarro G. Voltage sensor of excitation-contraction coupling in skeletal muscle. Physiol Rev 71 (1991) 849-908
38. 2+ release from sarcoplasmic reticulum. J Biol Chem 270 (1995) 3017-3021
39. Weisblat D.A., Byerly L., and Russell R.L. Ionic mechanisms of electrical activity in somatic muscle of the nematode Ascaris lumbricoides. J Comp Physiol 111 (1976) 93-113
40. Petrovic M.M., Vales K., Putnikovic B., Djulejic V., and Mitrovic D.M. Ryanodine receptors, voltage-gated calcium channels and their relationship with protein kinase A in the myocardium. Physiol Res 57 (2008) 141-149
41. 2+ channels. Annu Rev Cell Dev Biol 16 (2000) 521-555
42. Dunlap K. Calcium channels are models of self-control. J Gen Physiol 129 (2007) 379-383
43. 2+ selectivity in the calmodulin regulation of CaV channels. Nature 451 (2008) 830-834
44. Robertson A.P., and Martin R.J. Ion-channels on parasite muscle: pharmacology and physiology. Invert Neurosci 7 (2007) 209-217
45. Sakube Y., Ando H., and Kagawa H. An abnormal ketamine response in mutants defective in the ryanodine receptor gene ryr-1 (unc-68) of Caenorhabditis elegans. J Mol Biol 267 (1997) 849-864
46. Liu Q., Chen B., Yankova M., et al. Presynaptic ryanodine receptors are required for normal quantal size at the Caenorhabidits elegans neuromuscular junction. J Neurosci 25 (2005) 6745-6754
47. Salkoff L., Wei A.D., Baban B., et al. Potassium channels in C. elegans. WormBook (2005) 1-15