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Volumn 7, Issue , 2010, Pages

Moderate doses of conjugated linoleic acid reduce fat gain, maintain insulin sensitivity without impairing inflammatory adipose tissue status in mice fed a high-fat diet

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CONJUGATED LINOLEIC ACID; CYTOKINE; FATTY ACID; GLUCOSE; INSULIN; LEPTIN; TRIACYLGLYCEROL;

EID: 77649296864     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-7-5     Document Type: Article
Times cited : (28)

References (38)
  • 1
    • 33750935990 scopus 로고    scopus 로고
    • Biological effects of conjugated linoleic acids in health and disease
    • 10.1016/j.jnutbio.2006.02.009. 16650752
    • Biological effects of conjugated linoleic acids in health and disease. A Bhattacharya J Banu M Rahman J Causey G Fernandes, J Nutr Biochem 2006 17 789 810 10.1016/j.jnutbio.2006.02.009 16650752
    • (2006) J Nutr Biochem , vol.17 , pp. 789-810
    • Bhattacharya, A.1    Banu, J.2    Rahman, M.3    Causey, J.4    Fernandes, G.5
  • 2
    • 7444271915 scopus 로고    scopus 로고
    • Conjugated linoleic acids: Are they beneficial or detrimental to health?
    • 10.1016/j.plipres.2004.08.002. 15522764
    • Conjugated linoleic acids: are they beneficial or detrimental to health? KW Wahle SD Heys D Rotondo, Prog Lipid Res 2004 43 553 587 10.1016/j.plipres. 2004.08.002 15522764
    • (2004) Prog Lipid Res , vol.43 , pp. 553-587
    • Wahle, K.W.1    Heys, S.D.2    Rotondo, D.3
  • 3
    • 0347355025 scopus 로고    scopus 로고
    • Contribution of conjugated linoleic acid to the suppression of inflammatory responses through the regulation of the NF-kappaB pathway
    • 10.1021/jf0348626. 14709015
    • Contribution of conjugated linoleic acid to the suppression of inflammatory responses through the regulation of the NF-kappaB pathway. WL Cheng CK Lii HW Chen TH Lin KL Liu, J Agric Food Chem 2004 52 71 78 10.1021/jf0348626 14709015
    • (2004) J Agric Food Chem , vol.52 , pp. 71-78
    • Cheng, W.L.1    Lii, C.K.2    Chen, H.W.3    Lin, T.H.4    Liu, K.L.5
  • 6
    • 3242884783 scopus 로고    scopus 로고
    • Conjugated linoleic acid and obesity control: Efficacy and mechanisms
    • 10.1038/sj.ijo.0802641. 15254484
    • Conjugated linoleic acid and obesity control: efficacy and mechanisms. YW Wang PJ Jones, Int J Obes Relat Metab Disord 2004 28 941 955 10.1038/sj.ijo.0802641 15254484
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 941-955
    • Wang, Y.W.1    Jones, P.J.2
  • 7
    • 14544287769 scopus 로고    scopus 로고
    • Development of conjugated linoleic acid (CLA)-mediated lipoatrophic syndrome in the mouse
    • 10.1016/j.biochi.2004.11.006. 15733740
    • Development of conjugated linoleic acid (CLA)-mediated lipoatrophic syndrome in the mouse. H Poirier I Niot L Clement M Guerre-Millo P Besnard, Biochimie 2005 87 73 79 10.1016/j.biochi.2004.11.006 15733740
    • (2005) Biochimie , vol.87 , pp. 73-79
    • Poirier, H.1    Niot, I.2    Clement, L.3    Guerre-Millo, M.4    Besnard, P.5
  • 8
    • 0033861304 scopus 로고    scopus 로고
    • Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice
    • 10.2337/diabetes.49.9.1534. 10969838
    • Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. N Tsuboyama-Kasaoka M Takahashi K Tanemura HJ Kim T Tange H Okuyama M Kasai S Ikemoto O Ezaki, Diabetes 2000 49 1534 1542 10.2337/diabetes.49.9.1534 10969838
    • (2000) Diabetes , vol.49 , pp. 1534-1542
    • Tsuboyama-Kasaoka, N.1    Takahashi, M.2    Tanemura, K.3    Kim, H.J.4    Tange, T.5    Okuyama, H.6    Kasai, M.7    Ikemoto, S.8    Ezaki, O.9
  • 9
    • 0036739536 scopus 로고    scopus 로고
    • Dietary trans-10, cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse
    • 10.1194/jlr.M20008-JLR200. 12235171
    • Dietary trans-10, cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. L Clement H Poirier I Niot V Bocher M Guerre-Millo S Krief B Staels P Besnard, J Lipid Res 2002 43 1400 1409 10.1194/jlr.M20008-JLR200 12235171
    • (2002) J Lipid Res , vol.43 , pp. 1400-1409
    • Clement, L.1    Poirier, H.2    Niot, I.3    Bocher, V.4    Guerre-Millo, M.5    Krief, S.6    Staels, B.7    Besnard, P.8
  • 10
    • 34447499065 scopus 로고    scopus 로고
    • Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice
    • 10.1152/ajpgi.00523.2006. 17322064
    • Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice. LF Liu A Purushotham AA Wendel MA Belury, Am J Physiol Gastrointest Liver Physiol 2007 292 1671 1682 10.1152/ajpgi.00523.2006 17322064
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292 , pp. 71671-1682
    • Liu, L.F.1    Purushotham, A.2    Wendel, A.A.3    Belury, M.A.4
  • 11
    • 21344469235 scopus 로고    scopus 로고
    • Hyperinsulinaemia triggered by dietary conjugated linoleic acid is associated with a decrease in leptin and adiponectin plasma levels and pancreatic beta cell hyperplasia in the mouse
    • 10.1007/s00125-005-1765-8. 15868135
    • Hyperinsulinaemia triggered by dietary conjugated linoleic acid is associated with a decrease in leptin and adiponectin plasma levels and pancreatic beta cell hyperplasia in the mouse. H Poirier C Rouault L Clement I Niot MC Monnot M Guerre-Millo P Besnard, Diabetologia 2005 48 1059 1065 10.1007/s00125-005-1765-8 15868135
    • (2005) Diabetologia , vol.48 , pp. 1059-1065
    • Poirier, H.1    Rouault, C.2    Clement, L.3    Niot, I.4    Monnot, M.C.5    Guerre-Millo, M.6    Besnard, P.7
  • 12
    • 34248370966 scopus 로고    scopus 로고
    • Efficacy of conjugated linoleic acid for reducing fat mass: A meta-analysis in humans
    • 17490954
    • Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. LD Whigham AC Watras DA Schoeller, Am J Clin Nutr 2007 85 1203 1211 17490954
    • (2007) Am J Clin Nutr , vol.85 , pp. 1203-1211
    • Whigham, L.D.1    Watras, A.C.2    Schoeller, D.A.3
  • 13
    • 33644680390 scopus 로고    scopus 로고
    • Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production
    • 10.1074/jbc.M508159200. 16155293
    • Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production. S Chung JM Brown JN Provo R Hopkins MK McIntosh, J Biol Chem 2005 280 38445 38456 10.1074/jbc.M508159200 16155293
    • (2005) J Biol Chem , vol.280 , pp. 38445-38456
    • Chung, S.1    Brown, J.M.2    Provo, J.N.3    Hopkins, R.4    McIntosh, M.K.5
  • 14
    • 33748291462 scopus 로고    scopus 로고
    • Nutritional Supplementation with trans-10, cis-12-Conjugated Linoleic Acid Induces Inflammation of White Adipose Tissue
    • 10.2337/db06-0036. 16731825
    • Nutritional Supplementation With trans-10, cis-12-Conjugated Linoleic Acid Induces Inflammation of White Adipose Tissue. H Poirier JS Shapiro RJ Kim MA Lazar, Diabetes 2006 55 1634 1641 10.2337/db06-0036 16731825
    • (2006) Diabetes , vol.55 , pp. 1634-1641
    • Poirier, H.1    Shapiro, J.S.2    Kim, R.J.3    Lazar, M.A.4
  • 15
    • 33847399236 scopus 로고    scopus 로고
    • Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue
    • 10.2337/db06-0384. 17327424
    • Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue. F Moloney S Toomey E Noone A Nugent B Allan CE Loscher HM Roche, Diabetes 2007 56 574 582 10.2337/db06-0384 17327424
    • (2007) Diabetes , vol.56 , pp. 574-582
    • Moloney, F.1    Toomey, S.2    Noone, E.3    Nugent, A.4    Allan, B.5    Loscher, C.E.6    Roche, H.M.7
  • 16
    • 77949265771 scopus 로고    scopus 로고
    • Moderate doses of conjugated linoleic acid isomers mix contribute to lowering body fat content maintaining insulin sensitivity and a noninflammatory pattern in adipose tissue in mice
    • 19195867
    • Moderate doses of conjugated linoleic acid isomers mix contribute to lowering body fat content maintaining insulin sensitivity and a noninflammatory pattern in adipose tissue in mice. P Parra F Serra A Palou, J Nutr Biochem 2009 19195867
    • (2009) J Nutr Biochem
    • Parra, P.1    Serra, F.2    Palou, A.3
  • 17
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • 10.1093/nar/29.9.e45. 11328886
    • A new mathematical model for relative quantification in real-time RT-PCR. MW Pfaffl, Nucleic Acids Res 2001 29 45 10.1093/nar/29.9.e45 11328886
    • (2001) Nucleic Acids Res , vol.29 , pp. 545
    • Pfaffl, M.W.1
  • 18
    • 0037977719 scopus 로고    scopus 로고
    • Increasing the amount of fat in a conjugated linoleic acid-supplemented diet reduces lipodystrophy in mice
    • 12771319
    • Increasing the amount of fat in a conjugated linoleic acid-supplemented diet reduces lipodystrophy in mice. N Tsuboyama-Kasaoka H Miyazaki S Kasaoka O Ezaki, J Nutr 2003 133 1793 1799 12771319
    • (2003) J Nutr , vol.133 , pp. 1793-1799
    • Tsuboyama-Kasaoka, N.1    Miyazaki, H.2    Kasaoka, S.3    Ezaki, O.4
  • 19
    • 22744451979 scopus 로고    scopus 로고
    • Conjugated linoleic acid evokes de-lipidation through the regulation of genes controlling lipid metabolism in adipose and liver tissue
    • 10.1111/j.1467-789X.2005.00198.x. 16045640
    • Conjugated linoleic acid evokes de-lipidation through the regulation of genes controlling lipid metabolism in adipose and liver tissue. RL House JP Cassady EJ Eisen MK McIntosh J Odle, Obes Rev 2005 6 247 258 10.1111/j.1467-789X.2005.00198.x 16045640
    • (2005) Obes Rev , vol.6 , pp. 247-258
    • House, R.L.1    Cassady, J.P.2    Eisen, E.J.3    McIntosh, M.K.4    Odle, J.5
  • 20
    • 0036875066 scopus 로고    scopus 로고
    • Clinical trial results support a preference for using CLA preparations enriched with two isomers rather than four isomers in human studies
    • 10.1007/s11745-002-0995-y. 12558050
    • Clinical trial results support a preference for using CLA preparations enriched with two isomers rather than four isomers in human studies. JM Gaullier G Berven H Blankson O Gudmundsen, Lipids 2002 37 1019 1025 10.1007/s11745-002- 0995-y 12558050
    • (2002) Lipids , vol.37 , pp. 1019-1025
    • Gaullier, J.M.1    Berven, G.2    Blankson, H.3    Gudmundsen, O.4
  • 21
    • 0033808266 scopus 로고    scopus 로고
    • Conjugated linoleic acid persistently increases total energy expenditure in AKR/J mice without increasing uncoupling protein gene expression
    • 11015475
    • Conjugated linoleic acid persistently increases total energy expenditure in AKR/J mice without increasing uncoupling protein gene expression. DB West FY Blohm AA Truett JP DeLany, J Nutr 2000 130 2471 2477 11015475
    • (2000) J Nutr , vol.130 , pp. 2471-2477
    • West, D.B.1    Blohm, F.Y.2    Truett, A.A.3    Delany, J.P.4
  • 22
    • 0031708155 scopus 로고    scopus 로고
    • Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse
    • 9728060
    • Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. DB West JP Delany PM Camet F Blohm AA Truett J Scimeca, Am J Physiol 1998 275 667 672 9728060
    • (1998) Am J Physiol , vol.275 , pp. 18667-672
    • West, D.B.1    Delany, J.P.2    Camet, P.M.3    Blohm, F.4    Truett, A.A.5    Scimeca, J.6
  • 23
  • 24
    • 0141793762 scopus 로고    scopus 로고
    • Conjugated linoleic acid enhances plasma adiponectin level and alleviates hyperinsulinemia and hypertension in Zucker diabetic fatty (fa/fa) rats
    • 10.1016/j.bbrc.2003.09.044. 14521947
    • Conjugated linoleic acid enhances plasma adiponectin level and alleviates hyperinsulinemia and hypertension in Zucker diabetic fatty (fa/fa) rats. K Nagao N Inoue YM Wang T Yanagita, Biochem Biophys Res Commun 2003 310 562 566 10.1016/j.bbrc.2003.09.044 14521947
    • (2003) Biochem Biophys Res Commun , vol.310 , pp. 562-566
    • Nagao, K.1    Inoue, N.2    Wang, Y.M.3    Yanagita, T.4
  • 25
    • 20044395616 scopus 로고    scopus 로고
    • Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: Possible involvement of PPAR activation
    • 10.1186/1476-511X-4-3. 15642120
    • Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation. E Wargent MV Sennitt C Stocker AE Mayes L Brown J O'Dowd S Wang AW Einerhand I Mohede JR Arch MA Cawthorne, Lipids Health Dis 2005 4 3 10.1186/1476-511X-4-3 15642120
    • (2005) Lipids Health Dis , vol.4 , pp. 3
    • Wargent, E.1    Sennitt, M.V.2    Stocker, C.3    Mayes, A.E.4    Brown, L.5    O'Dowd, J.6    Wang, S.7    Einerhand, A.W.8    Mohede, I.9    Arch, J.R.10    Cawthorne, M.A.11
  • 27
    • 33846877211 scopus 로고    scopus 로고
    • Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice
    • 10.1194/jlr.M600393-JLR200. 17050906
    • Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. A Purushotham AA Wendel LF Liu MA Belury, J Lipid Res 2007 48 444 452 10.1194/jlr.M600393-JLR200 17050906
    • (2007) J Lipid Res , vol.48 , pp. 444-452
    • Purushotham, A.1    Wendel, A.A.2    Liu, L.F.3    Belury, M.A.4
  • 29
    • 17044375113 scopus 로고    scopus 로고
    • Conjugated linoleic acid deteriorates insulin resistance in obese/diabetic mice in association with decreased production of adiponectin and leptin
    • 15895517
    • Conjugated linoleic acid deteriorates insulin resistance in obese/diabetic mice in association with decreased production of adiponectin and leptin. A Ohashi Y Matsushita K Kimura K Miyashita M Saito, J Nutr Sci Vitaminol (Tokyo) 2004 50 416 421 15895517
    • (2004) J Nutr Sci Vitaminol (Tokyo) , vol.50 , pp. 416-421
    • Ohashi, A.1    Matsushita, Y.2    Kimura, K.3    Miyashita, K.4    Saito, M.5
  • 30
    • 41549125848 scopus 로고    scopus 로고
    • Effect of leptin infusion on insulin sensitivity and lipid metabolism in diet-induced lipodystrophy model mice
    • 10.1186/1476-511X-7-8. 18348717
    • Effect of leptin infusion on insulin sensitivity and lipid metabolism in diet-induced lipodystrophy model mice. K Nagao N Inoue Y Ujino K Higa B Shirouchi YM Wang T Yanagita, Lipids Health Dis 2008 7 8 10.1186/1476-511X-7-8 18348717
    • (2008) Lipids Health Dis , vol.7 , pp. 8
    • Nagao, K.1    Inoue, N.2    Ujino, Y.3    Higa, K.4    Shirouchi, B.5    Wang, Y.M.6    Yanagita, T.7
  • 31
    • 12744262842 scopus 로고    scopus 로고
    • Interaction of fish oil and conjugated linoleic acid in affecting hepatic activity of lipogenic enzymes and gene expression in liver and adipose tissue
    • 10.2337/diabetes.54.2.412. 15677499
    • Interaction of fish oil and conjugated linoleic acid in affecting hepatic activity of lipogenic enzymes and gene expression in liver and adipose tissue. T Ide, Diabetes 2005 54 412 423 10.2337/diabetes.54.2.412 15677499
    • (2005) Diabetes , vol.54 , pp. 412-423
    • Ide, T.1
  • 32
    • 34548043306 scopus 로고    scopus 로고
    • The biochemical assessment of insulin resistance
    • 10.1258/000456307780945778. 17594780
    • The biochemical assessment of insulin resistance. A Borai C Livingstone GA Ferns, Ann Clin Biochem 2007 44 324 342 10.1258/000456307780945778 17594780
    • (2007) Ann Clin Biochem , vol.44 , pp. 324-342
    • Borai, A.1    Livingstone, C.2    Ferns, G.A.3
  • 33
    • 0034751604 scopus 로고    scopus 로고
    • Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals
    • 10.1210/jc.86.10.4776. 11600540
    • Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals. G Perseghin A Caumo M Caloni G Testolin L Luzi, J Clin Endocrinol Metab 2001 86 4776 4781 10.1210/jc.86.10.4776 11600540
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4776-4781
    • Perseghin, G.1    Caumo, A.2    Caloni, M.3    Testolin, G.4    Luzi, L.5
  • 34
    • 33947405131 scopus 로고    scopus 로고
    • Trans-10, cis-12 conjugated linoleic acid causes inflammation and delipidation of white adipose tissue in mice: A microarray and histological analysis
    • 10.1152/physiolgenomics.00076.2006. 16868072
    • Trans-10, cis-12 conjugated linoleic acid causes inflammation and delipidation of white adipose tissue in mice: a microarray and histological analysis. PC LaRosa J Miner Y Xia Y Zhou S Kachman ME Fromm, Physiol Genomics 2006 27 282 294 10.1152/physiolgenomics.00076.2006 16868072
    • (2006) Physiol Genomics , vol.27 , pp. 282-294
    • Larosa, P.C.1    Miner, J.2    Xia, Y.3    Zhou, Y.4    Kachman, S.5    Fromm, M.E.6
  • 35
    • 2942755860 scopus 로고    scopus 로고
    • Conjugated linoleic acid induces human adipocyte delipidation: Autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines
    • 10.1074/jbc.M401766200. 15067015
    • Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines. JM Brown MS Boysen S Chung O Fabiyi RF Morrison S Mandrup MK McIntosh, J Biol Chem 2004 279 26735 26747 10.1074/jbc.M401766200 15067015
    • (2004) J Biol Chem , vol.279 , pp. 26735-26747
    • Brown, J.M.1    Boysen, M.S.2    Chung, S.3    Fabiyi, O.4    Morrison, R.F.5    Mandrup, S.6    McIntosh, M.K.7
  • 36
    • 33750602672 scopus 로고    scopus 로고
    • Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice
    • 10.1038/oby.2006.153. 16988077
    • Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice. R Yu CS Kim BS Kwon T Kawada, Obesity (Silver Spring) 2006 14 1353 1362 10.1038/oby.2006.153 16988077
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 1353-1362
    • Yu, R.1    Kim, C.S.2    Kwon, B.S.3    Kawada, T.4
  • 37
    • 0242580711 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
    • 10.1074/jbc.M301977200. 12952969
    • Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. V Rotter I Nagaev U Smith, J Biol Chem 2003 278 45777 45784 10.1074/jbc.M301977200 12952969
    • (2003) J Biol Chem , vol.278 , pp. 45777-45784
    • Rotter, V.1    Nagaev, I.2    Smith, U.3
  • 38
    • 0038809142 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 in obesity and insulin resistance
    • 10.1073/pnas.1133870100. 12756299
    • Monocyte chemoattractant protein 1 in obesity and insulin resistance. P Sartipy DJ Loskutoff, Proc Natl Acad Sci USA 2003 100 7265 7270 10.1073/pnas.1133870100 12756299
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7265-7270
    • Sartipy, P.1    Loskutoff, D.J.2


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