MicroRNA expression in ileal carcinoid tumors: Downregulation of microRNA-133a with tumor progression

Modern Pathology

Volumn 23, Issue 3, 2010, Pages 367-375

  Ruebel, Katharina ^a   Leontovich, Alexey A ^a   Stilling, Gail A ^a   Zhang, Shuya ^a   Righi, Alberto ^a   Jin, Long ^a   Lloyd, Ricardo V ^a  

^a MAYO CLINIC   (United States)

Author keywords

Carcinoids; Enterochromaffin cells; In situ hybridization; PCR array; RT PCR

Indexed keywords

MICRORNA;

ADULT; APOPTOSIS; ARTICLE; CARCINOID; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CLINICAL ARTICLE; ENTEROCHROMAFFIN CELL; FEMALE; HUMAN; ILEUM TUMOR; IN SITU HYBRIDIZATION; LASER CAPTURE MICRODISSECTION; MALE; NEUROENDOCRINE TUMOR; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ADULT; BLOTTING, NORTHERN; CARCINOID TUMOR; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; HUMANS; ILEAL NEOPLASMS; MALE; MICROARRAY ANALYSIS; MICRODISSECTION; MICRORNAS; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; TUMOR MARKERS, BIOLOGICAL;

EID: 77649273009     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2009.161     Document Type: Article

References (42)

1. Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6:857-866, review.
2. Esquela-Kerscher A, Slack FJ. Oncomirs: microRNAs with a role in cancer. Nat Rev Cancer 2006;6:259-269.
3. Barbarotto E, Schmittgen TD, Calin GA. MicroRNAs and cancer: profile, profile, profile. Int J Cancer 2008; 122:969-977.
4. Kent OA, Mendell JT. A small piece in the cancer puzzle; microRNAs as tumor suppressors and onco-genes. Oncogene 2006;25:6188-6196.
5. Valencia-Sanchez MA, Liu J, Hannon GJ, et al. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev 2006;20:515-524.
6. Garson R, Fabbri M, Cimmino A, et al. MicroRNA expression and function in cancer. Trends Mol Med 2006;12:580-587.
7. Zhang W, Dahlberg JE, Tam W. MicroRNAs in tumor-igenesis: a primer. Am J Pathol 2007;177:728-738.
8. Modin IM, Oberg K, Chung DC, et al. Gastroentero-pancreatic neuroendocrine tumours. Lancet Oncol 2008;9:61-72.
9. Oberg K. Genetics and molecular pathology of neu-roendocrine gastrointestinal and pancreatic tumors (gastroenteropancreatic neuroendocrine tumors. Curr Opin Endocrinol Diabetes Obes 2009;16:72-78.
10. Nilsson O, Wangberg B, McRae A, et al. Growth factors and carcinoid tumours. Acta Oncol 1993;32:115-124.
11. Oberg K. Expression of growth factors and their receptors in neuroendocrine gut and pancreatic tumors, and prognostic factors for survival. Ann N Y Acad Sci 2005;733:46-55.
12. Papouchado B, Erickson LA, Rohlinger AL, et al. Epidermal growth factor receptor and activated epidermal growth factor receptor expression in gastrointestinal carcinoids and pancreatic endocrine carcinomas. Mod Pathol 2005;18:1329-1335.
13. Stilling GA, Zhang H, Ruebel KH, et al. Characterization of the functional and growth properties of cell lines established from ileal and rectal carcinoid tumors. Endocr Pathol 2007;18:223-232.
14. Zhang HY, Rumilla KM, Jin L, et al. Association of DNA methylation and epigenetic inactivation of RASSF1A and beta catenin with metastasis in small bowel carcinoid tumors. Endocrine 2006;30:299-306.
15. Modlin IM, Kidd M, Pfragner R, et al. The functional characterization of normal and neoplastic human enterochromaffin cells. J Clin Endocrinol Metab 2006;91:2340-2348. (Pubitemid 43855026)
16. Modlin IM, Kidd M, Drozdov I, et al. Pharmacotherapy of neuroendocrine cancers. Expert Opin Pharmacother 2008;9:2617-2626.
17. Hobday TJ, Mahoney M, Erlichman C, et al. Preliminary results of a phase II trial of gefitinib in progressive metastatic neuroendocrine tumors (NET); A phase II consortium (P2C) study (Abstract 4083). J Clin Oncol 2005;23(part 1):328s.
18. Nakamura N, Ruebel K, Jin L, et al. Laser capture microdissection for analysis of single cells. Methods Mol Med 2007;132:11-18.
19. Leja J, Essaghir A, Essand M, et al. Novel markers for enterochromaffin cells and gastrointestinal neuroen-docrine carcinomas. Mod Pathol 2009;22:261-272.
20. Riss D, Jin L, Qian X, et al. Differential expression of galectin-3 in pituitary tumors. Cancer Res 2003; 63:2251-2255.
21. Nelson PT, Baldwin DA, Kloosteman WP, et al. Rake and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA 2006; 12:187-191.
22. Thomsen R, Nielsen PS, Jensen TH. Dramatically improved RNA in situ hybridization signals using LNA-modified probes. RNA 2005;11:1745-1748.
23. Nuovo GJ. In situ detection of precursor and mature microRNAs in paraffin embedded, formalin-fixed tissues and cell preparations. Methods 2008;44:39-46, review.
24. Chen JF, Mandel EM, Thomson JM, et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006;38:228-233.
25. Care A, Catalucci D, Felicetti F, et al. MicroRNA-133 controls cardiac hypertrophy. Nat Med 2007;13:613-618.
26. Luo X, Lin H, Pan Z, et al. Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. J Biol Chem 2008;283:20045-20052.
27. McCarthy JJ, Esser KA. MicroRNA-1 and microRNA-133a expression are decreased during skeletal muscle hypertrophy. J Appl Physiol 2007;102:306-313.
28. Wong TS, Liu XB, Chung-Wai HA, et al. Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling. Int J Cancer 2008;123:251-257.
29. Datta J, Kutay H, Nasser MW, et al. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res 2008; 68:5049-5058.
30. Nasser MW, Datta J, Nuovo G, et al. Down-regulation of micro-RNa-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J Biol Chem 2008;283:33394-33405.
31. Sempere LF, Freemantle S, Pitha-Rowe I, et al. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 2004;5:R13-R13.11.
32. Slezak S, Jin P, Caruccio L, et al. Gene and microRNa analysis of neutrophils from patients with polycythe-mia vera and essential thrombocytosis: down-regulation of micro RNA-1 and-133a. J Transl Med 2009;7:39, PubMed, in process.
33. Xu C, Lu Y, Pan Z, et al. The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 2007;120:3045-3052.
34. Cho WC, Chow AS, Au JS. Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur J Cancer 2009;45: 2197-2206.
35. Takagi T, Ilio A, Nakagawa Y, et al. Decreased expression of MicroRNA-143 and-145 in human gastric cancers. Oncology 2009;77:12-21.
36. Hurst DR, Edmonds MD, Scott GK, et al. Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res 2009;69:1279-1283.
37. Zhang C, Kang C, You Y, et al. Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. Int J Oncol 2009;34:1653-1660.
38. Schwertheim S, Sheu SY, Worm K, et al. Analysis of deregulated miRNAs is helpful to distinguish poorly differentiated thyroid carcinoma from papillary thyroid carcinoma. Horm Metab Res 2009;41:475-481.
39. Sun T, Wang Q, Balk S, et al. The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines. Cacner Res 2009;69: 3356-3363.
40. Sasayama T, Nishihara M, Kondoh T, et al. MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC. Int J Cancer 2009;125:1407-1413.
41. Ma L, Teruya-Feldstein J, Weinberg RA. Tumor invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007;449:682-688.
42. Motoyama K, Inoue H, Takatsuno Y, et al. Over-and under-expressed microRNAs in human colorectal cancer. Int J Oncol 2009;34:1069-1075.