The effect of immobilization of thrombin inhibitors onto self-assembled monolayers on the adsorption and activity of thrombin

Biomaterials

Volumn 31, Issue 14, 2010, Pages 3772-3780

  Freitas, Sidónio C ^a,b   Barbosa, Mário A ^a,b   Martins, M Cristina L ^a  

^a INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Peptide immobilization; Protein adsorption; Self assembled monolayers; Surface functionalization; Thrombin

Indexed keywords

BLOOD CLOTTING; BLOOD CONTACT; CARBONYLDIIMIDAZOLE; COAGULATION SYSTEM; CONCENTRATION-DEPENDENT; D-PHENYLALANINE; HEMOCOMPATIBILITY; INFRARED REFLECTION ABSORPTION SPECTROSCOPY; MEDICAL DEVICES; NANOSTRUCTURED SURFACE; PEPTIDE IMMOBILIZATION; PROTEIN ADSORPTION; SAMS; SERINE PROTEASE; SURFACE FUNCTIONALIZATION; THROMBIN INHIBITORS; THROMBUS FORMATION;

ABSORPTION SPECTROSCOPY; ADSORPTION; AMINO ACIDS; ANGLE MEASUREMENT; BIOMATERIALS; BLOOD; COAGULATION; CONTACT ANGLE; ETHYLENE; ETHYLENE GLYCOL; INFRARED SPECTROSCOPY; PEPTIDES; PHOSPHATASES; X RAY PHOTOELECTRON SPECTROSCOPY;

SELF ASSEMBLED MONOLAYERS;

CARBONYLDIIMIDAZOLE; ETHYLENE GLYCOL DERIVATIVE; IMIDAZOLE DERIVATIVE; PEPTIDE; PHENYLALANYLPROLYLARGINYLPROLYLGLYCINE; TETRA(ETHYLENE GLYCOL); THROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ADSORPTION KINETICS; AMINO ACID SEQUENCE; ARTICLE; CONCENTRATION (PARAMETERS); CONTACT ANGLE; ELLIPSOMETRY; INFRARED SPECTROSCOPY; ISOTOPE LABELING; MONOLAYER CULTURE; NANOANALYSIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN IMMOBILIZATION; QUANTITATIVE STUDY; X RAY PHOTOELECTRON SPECTROSCOPY;

ADSORPTION; ALBUMINS; GOLD; HUMANS; IMMOBILIZED PROTEINS; IODINE RADIOISOTOPES; PEPTIDES; SOLUBILITY; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; THROMBIN;

TETRA;

EID: 77649271932     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.01.097     Document Type: Article

References (39)

1. Gorbet M.B., and Sefton M.V. Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes. Biomaterials 25 26 (2004) 5681-5703
2. Ratner B.D., Hoffman A.F., Schoen F.J., and Lemons J.L. Biomaterials science - an introduction to materials in medicine. 2nd ed. (2004), Elsevier Academic Press, San Diego, CA, USA
3. Bode W. Structure and interaction modes of thrombin. Blood Cells Mol Dis 36 2 (2006) 122-130
4. Huntington J.A. Molecular recognition mechanisms of thrombin. J Thromb Haemost 3 8 (2005) 1861-1872
5. Schwienhorst A. Direct thrombin inhibitors - a survey of recent developments. Cell Mol Life Sci 63 23 (2006) 2773-2791
6. Tseng P.-Y., Rele S.S., Sun X.-L., and Chaikof E.L. Membrane-mimetic films containing thrombomodulin and heparin inhibit tissue factor-induced thrombin generation in a flow model. Biomaterials 27 12 (2006) 2637-2650
7. Sperling C., Salchert K., Streller U., and Werner C. Covalently immobilized thrombomodulin inhibits coagulation and complement activation of artificial surfaces in vitro. Biomaterials 25 21 (2004) 5101-5113
8. Lin J.C., and Tseng S.M. Surface characterization and platelet adhesion studies on polyethylene surface with hirudin immobilization. J Mater Sci Mater Med 12 9 (2001) 827-832
9. Wendel H.P., and Ziemer G. Coating-techniques to improve the hemocompatibility of artificial devices used for extracorporeal circulation. Eur J Cardiothorac Surg 16 3 (1999) 342-350
10. Werner C., Maitz M.F., and Sperling C. Current strategies towards hemocompatible coatings. J Mater Chem 17 32 (2007) 3376-3384
11. Weitz J.I., and Crowther M. Direct thrombin inhibitors. Thromb Res 106 3 (2002) V275-V284
12. Di Nisio M., Middeldorp S., and Büller H.R. Direct thrombin inhibitors. N Engl J Med 353 10 (2005) 1028-1040
13. Stone S.R., and Hofsteenge J. Kinetics of the inhibition of thrombin by hirudin. Biochemistry 25 16 (1986) 4622-4628
14. Grutter M.G., Priestle J., Rahuel J., Grossenbacher H., Bode W., Hofsteenge J., et al. Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition. EMBO J 9 8 (1990) 2361-2365
15. Lahann J., Plüster W., Klee D., Gattner H.G., and Höcker H. Immobilization of the thrombin inhibitor r-hirudin conserving its biological activity. J Mater Sci Mater Med 12 9 (2001) 807-810
16. Phaneuf M.D., Berceli S.A., Bide M.J., Quist W.C., and LoGerfo F.W. Covalent linkage of recombinant hirudin to poly(ethylene terephthalate) (Dacron): creation of a novel antithrombin surface. Biomaterials 18 10 (1997) 755-765
17. Wyers M.C., Phaneuf M.D., Rzucidlo E.M., Contreras M.A., Logerfo F.W., and Quist W.C. In vivo assessment of a novel Dacron surface with covalently bound recombinant hirudin. Cardiovasc Pathol 8 3 (1999) 153-159
18. Maraganore J.M., Bourdon P., Jablonski J., Ramachandran K.L., and Fenton Ii J.W. Design and characterization of hirulogs: a novel class of bivalent peptide inhibitors of thrombin. Biochemistry 29 30 (1990) 7095-7101
19. Maraganore J.M., Chao B., Joseph M.L., Jablonski J., and Ramachandran K.L. Anticoagulant activity of synthetic hirudin peptides. J Biol Chem 264 15 (1989) 8692-8698
20. Sun X., Sheardown H., Tengvall P., and Brash J.L. Peptide modified gold-coated polyurethanes as thrombin scavenging surfaces. J Biomed Mater Res 49 1 (2000) 66-78
21. Bain C.D., Troughton E.B., Tao Y.T., Evall J., Whitesides G.M., and Nuzzo R.G. Formation of monolayer films by the spontaneous assembly of organic thiols from solution onto gold. J Am Chem Soc 111 1 (1989) 321-335
22. Herrwerth S., Eck W., Reinhardt S., and Grunze M. Factors that determine the protein resistance of oligoether self-assembled monolayers - internal hydrophilicity, terminal hydrophilicity, and lateral packing density. J Am Chem Soc 125 31 (2003) 9359-9366
23. Lottenberg R., Christensen U., Jackson C.M., and Coleman P.L. Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates. Meth Enzymol 80 Pt C (1981) 341-361
24. Martins M.C.L., Ratner B.D., and Barbosa M.A. Protein adsorption on mixtures of hydroxyl- and methyl-terminated alkanethiols self-assembled monolayers. J Biomed Mater Res A 67A 1 (2003) 158-171
25. Martins M.C.L., Curtin S.A., Freitas S.C., Salgueiro P., Ratner B.D., and Barbosa M.A. Molecularly designed surfaces for blood deheparinization using an immobilized heparin-binding peptide. J Biomed Mater Res A 88 1 (2009) 162-173
26. Iodine-125. A guide to radioiodination techniques (1993), Amersham Life Science, Little Chalfort
27. Rahmelow K., Hubner W., and Ackermann T. Infrared absorbances of protein side chains. Anal Biochem 257 1 (1998) 1-11
28. Barth A. The infrared absorption of amino acid side chains. Prog Biophys Mol Biol 74 3-5 (2000) 141-173
29. Li L., Chen S., Zheng J., Ratner B.D., and Jiang S. Protein adsorption on oligo(ethylene glycol)-terminated alkanethiolate self-assembled monolayers: the molecular basis for nonfouling behavior. J Phys Chem B 109 7 (2005) 2934-2941
30. Beamson G., and Briggs D. High resolution XPS of organic polymers (1992), John Wiley and Sons, Ltd;, New York
31. Adden N., Gamble L.J., Castner D.G., Hoffmann A., Gross G., and Menzel H. Phosphonic acid monolayers for binding of bioactive molecules to titanium surfaces. Langmuir 22 19 (2006) 8197-8204
32. 2 from single protein solutions and from plasma. Langmuir 20 22 (2004) 9745-9754
33. Di Cera E. Thrombin interactions. Chest 124 Suppl. 3 (2003) 11S-17S
34. Markwardt F. Historical perspective of the development of thrombin inhibitors. Pathophysiol Haemost Thromb 32 Suppl. 3 (2002) 15-22
35. Hearn M.T. 1,1′-Carbonyldiimidazole-mediated immobilization of enzymes and affinity ligands. Methods Enzymol 135 (1987) 102-117
36. Stöllner D., Scheller F.W., and Warsinke A. Activation of cellulose membranes with 1,1′-carbonyldiimidazole or 1-cyano-4-dimethylaminopyridinium tetrafluoroborate as a basis for the development of immunosensors. Anal Biochem 304 2 (2002) 157-165
37. Martins M.C.L., Naeemi E., Ratner B.D., and Barbosa M.A. Albumin adsorption on Cibacron Blue F3G-A immobilized onto oligo(ethylene glycol)- terminated self-assembled monolayers. J Mater Sci Mater Med 14 11 (2003) 945-954
38. Dee K.C., Puleo D.A., and Bizios R. An introduction to tissue-biomaterial interactions (2002), Wiley-Liss, Inc.
39. Malmsten M., and Lassen B. Competitive adsorption at hydrophobic surfaces from binary protein systems. J Colloid Interface Sci 166 2 (1994) 490-498