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Volumn 33, Issue 3, 2010, Pages 658-660

Lipotoxicity and decreased islet graft survival

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CORTICOSTEROID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 77649267543     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc09-1387     Document Type: Article
Times cited : (18)

References (15)
  • 1
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    • Beta-cell lipotoxicity in the pathogenesis of non-insulindependent diabetes mellitus of obese rats: Impairment in adipocyte-beta-cell relationships
    • Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, Unger RH. Beta-cell lipotoxicity in the pathogenesis of non-insulindependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci U S A 1994; 91:10878-10882
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10878-10882
    • Lee, Y.1    Hirose, H.2    Ohneda, M.3    Johnson, J.H.4    McGarry, J.D.5    Unger, R.H.6
  • 3
    • 0028268936 scopus 로고
    • Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • Zhou YP, Grill VE. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 1994;93:870-876
    • (1994) J Clin Invest , vol.93 , pp. 870-876
    • Zhou, Y.P.1    Grill, V.E.2
  • 5
    • 0032488968 scopus 로고    scopus 로고
    • Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats
    • Shimabukuro M, Zhou YT, Lee Y, Unger RH. Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats. J Biol Chem 1998;273:3547-3550
    • (1998) J Biol Chem , vol.273 , pp. 3547-3550
    • Shimabukuro, M.1    Zhou, Y.T.2    Lee, Y.3    Unger, R.H.4
  • 6
    • 0034682474 scopus 로고    scopus 로고
    • Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets
    • Kakuma T, Lee Y, Higa M, Wang Z, Pan W, Shimomura I, Unger RH. Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets. Proc Natl Acad Sci U S A 2000;97:8536-8541
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8536-8541
    • Kakuma, T.1    Lee, Y.2    Higa, M.3    Wang, Z.4    Pan, W.5    Shimomura, I.6    Unger, R.H.7
  • 9
    • 0037678416 scopus 로고    scopus 로고
    • Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: A functional footprint of islet graft survival?
    • Markmann JF, Rosen M, Siegelman ES, Soulen MC, Deng S, Barker CF, Naji A. Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: a functional footprint of islet graft survival? Diabetes 2003;52: 1591-1594
    • (2003) Diabetes , vol.52 , pp. 1591-1594
    • Markmann, J.F.1    Rosen, M.2    Siegelman, E.S.3    Soulen, M.C.4    Deng, S.5    Barker, C.F.6    Naji, A.7
  • 11
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004;114:147-152
    • (2004) J Clin Invest , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 14
    • 34548433579 scopus 로고    scopus 로고
    • Metabolic mechanisms of failure of intraportally transplanted pancreatic β-cells in rats: Role of lipotoxicity and prevention by leptin
    • Lee Y, Ravazzola M, Park BH, Bashmakov YK, Orci L, Unger RH. Metabolic mechanisms of failure of intraportally transplanted pancreatic β-cells in rats: role of lipotoxicity and prevention by leptin. Diabetes 2007;56:2295-2301
    • (2007) Diabetes , vol.56 , pp. 2295-2301
    • Lee, Y.1    Ravazzola, M.2    Park, B.H.3    Bashmakov, Y.K.4    Orci, L.5    Unger, R.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.