DNA repair mutant pso2 of Saccharomyces cerevisiae is sensitive to intracellular acetaldehyde accumulated by disulfiram-mediated inhibition of acetaldehyde dehydrogenase

Genetics and Molecular Research

Volumn 9, Issue 1, 2010, Pages 48-57

  Brendel, M ^a   Marisco, G ^a   Ganda, I ^a   Wolter, R ^b   Pungartnik, C ^a  

^a DEPARTAMENTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

^b MEDA Pharma GmbH and Co KG   (Germany)

Author keywords

Acetaldehyde; Aldehyde dehydrogenase; Disulfiram; DNA repair; Interstrand cross links; Mutation induction

Indexed keywords

ALDEHYDE DEHYDROGENASE; BETA GALACTOSIDASE; CHLORMETHINE; DISULFIRAM; GLUCOSE; PSORALEN;

ARTICLE; CELL VIABILITY; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; ENZYME INHIBITION; EXPOSURE; FUNGAL GENE; FUNGUS MUTANT; GENE EXPRESSION; NONHUMAN; PSO2 GENE; REPORTER GENE; SACCHAROMYCES CEREVISIAE; SPONTANEOUS MUTATION; WILD TYPE;

ACETALDEHYDE; ALCOHOL DETERRENTS; ALDEHYDE OXIDOREDUCTASES; AMINO ACID TRANSPORT SYSTEMS, BASIC; DISULFIRAM; DNA DAMAGE; DNA REPAIR; DNA, FUNGAL; DNA-BINDING PROTEINS; HUMANS; MUTAGENESIS; MUTATION; NUCLEAR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 77649260038     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/vol9-1gmr695     Document Type: Article

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