Identification of an unconventional E3 binding surface on the UbcH5 ∼ Ub conjugate recognized by a pathogenic bacterial E3 ligase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 7, 2010, Pages 2848-2853

  Levin, Itay ^a   Eakin, Catherine ^b   Blanc, Marie Pierre ^a   Klevit, Rachel E ^b   Miller, Samuel I ^a   Brzovic, Peter S ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

E2 ubiquitin conjugating enzyme; HECT; Salmonella SspH2 effector; Ubiquitin ligase; Ubiquitination

Indexed keywords

CELL PROTEIN; E3 LIGASE; LIGASE; POLYPEPTIDE; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME H5; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CONJUGATION; ENZYME BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN TARGETING; SALMONELLA TYPHIMURIUM; SURFACE PROPERTY; SYNTHESIS;

BACTERIAL PROTEINS; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

BACTERIA (MICROORGANISMS); EUKARYOTA; NEGIBACTERIA; SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 77649242746     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914821107     Document Type: Article

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