Direct effects of delta opioid receptor agonists on invasion-associated activities of HCT-8/E11 colon cancer cells

Anticancer Research

Volumn 30, Issue 1, 2010, Pages 9-18

  Debruyne, Delphine ^a   Leroy, Ancy ^b   De Wever, Olivier ^a   Vakaet, Luc ^c   Mareel, Marc ^a   Bracke, Marc ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY COLLEGE GHENT   (Belgium)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Cell growth; Cell cell adhesion; Invasion; Migration

Indexed keywords

COLLAGEN; DELTA OPIATE RECEPTOR AGONIST; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE];

ARTICLE; CANCER CELL; CANCER INVASION; CELL ACTIVITY; CELL ADHESION; CELL GROWTH; CELL MIGRATION; CELL STIMULATION; COLON CANCER; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANIMALS; CELL ADHESION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL MOVEMENT; CHICK EMBRYO; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALINS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM INVASIVENESS; PHOSPHORYLATION; RECEPTORS, OPIOID, DELTA; SPHEROIDS, CELLULAR;

EID: 77649241603     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Bostwick DG, Null WE, Holmes D, Weber E, Barchas JD and Bensch KG: Expression of opioid peptides in tumors. N Engl J Med 317: 1439-1443, 1987.
2. Lundberg JM, Hamberger B, Schultzberg M, Hokfelt T, Granberg PO, Efendic S, Terenius L, Goldstein M and Luft R: Enkephalin-and somatostatin-like immunoreactivities in human adrenal medulla and pheochromocytoma. Proc Natl Acad Sci USA 76: 4079-4083, 1979.
3. Zagon IS, McLaughlin PJ, Goodman SR and Rhodes RE: Opioid receptors and endogenous opioids in diverse human and animal cancers. J Natl Cancer Inst 79: 1059-1065, 1987.
4. Cerpa-Poljak A, Lahnstein J, Mason KE, Smythe GA and Duncan MW: Mass spectrometric identification and quantification of hemorphins extracted from human adrenal and pheochromocytoma tissue. J Neurochem 68: 1712-1719, 1997.
5. Oliveira MJ, Van DJ, Lauwaet T, De C, V, De BG, Verschraegen G, Vaneechoutte M, Goethals M, Ahmadian MR, Muller O, Vandekerckhove J, Mareel M and Leroy A: Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility. EMBO J 22: 6161-6173, 2003.
6. Scholar EM, Violi L and Hexum TD: The antimetastatic activity of enkephalin-like peptides. Cancer Lett 35: 133-138, 1987.
7. Mousa SA, Shakibaei M, Sitte N, Schafer M and Stein C: Subcellular pathways of beta-endorphin synthesis, processing, and release from immunocytes in inflammatory pain. Endocrinology 145: 1331-1341, 2004.
8. Gkonos PJ, Krongrad A and Roos BA: Neuroendocrine peptides in the prostate. Urol Res 23: 81-87, 1995.
9. Page GG, Ben-Eliyahu S, Yirmiya R and Liebeskind JC: Morphine attenuates surgery-induced enhancement of metastatic colonization in rats. Pain 54: 21-28, 1993.
10. Shavit Y, Ben-Eliyahu S, Zeidel A and Beilin B: Effects of fentanyl on natural killer cell activity and on resistance to tumor metastasis in rats. Dose and timing study. Neuroimmunomodulation 11: 255-260, 2004.
11. Gupta K, Kshirsagar S, Chang L, Schwartz R, Law PY, Yee D and Hebbel RP: Morphine stimulates angiogenesis by activating proangiogenic and survival-promoting signaling and promotes breast tumor growth. Cancer Res 62: 4491-4498, 2002.
12. Harimaya Y, Koizumi K, Andoh T, Nojima H, Kuraishi Y and Saiki I: Potential ability of morphine to inhibit the adhesion, invasion and metastasis of metastatic colon 26-L5 carcinoma cells. Cancer Lett 187: 121-127, 2002.
13. Hatzoglou A, Bakogeorgou E and Castanas E: The antiproliferative effect of opioid receptor agonists on the T47D human breast cancer cell line, is partially mediated through opioid receptors. Eur J Pharmacol 296: 199-207, 1996.
14. Kallergi G, Tsapara A, Kampa M, Papakonstanti EA, Krasagakis K, Castanas E and Stournaras C: Distinct signaling pathways regulate differential opioid effects on actin cytoskeleton in malignant MCF7 and nonmalignant MCF12A human breast epithelial cells. Exp Cell Res 288: 94-109, 2003.
15. Kampa M, Bakogeorgou E, Hatzoglou A, Damianaki A, Martin PM and Castanas E: Opioid alkaloids and casomorphin peptides decrease the proliferation of prostatic cancer cell lines (LNCaP, PC3 and DU145) through a partial interaction with opioid receptors. Eur J Pharmacol 335: 255-265, 1997.
16. Ogasawara M, Murata J, Ayukawa K and Saiki I: Differential effect of intestinal neuropeptides on invasion and migration of colon carcinoma cells in vitro. Cancer Lett 119: 125-130, 1997.
17. Papakonstanti EA, Bakogeorgou E, Castanas E, Emmanouel DS, Hartig R and Stournaras C: Early alterations of actin cytoskeleton in OK cells by opioids. J Cell Biochem 70: 60-69, 1998.
18. 1 cell cycle block and apoptosis with morphine in adenocarcinoma cells: involvement of p53 phosphorylation. Cancer Res 63: 1846-1852, 2003.
19. Yin DL, Ren XH, Zheng ZL, Pu L, Jiang LZ, Ma L and Pei G: Etorphine inhibits cell growth and induces apoptosis in SK-N-SH cells: involvement of pertussis toxin-sensitive G proteins. Neurosci Res 29: 121-127, 1997.
20. Zagon IS and McLaughlin PJ: Opioids and the apoptotic pathway in human cancer cells. Neuropeptides 37: 79-88, 2003.
21. Zagon IS, Rahn KA and McLaughlin PJ: Opioids and migration, Chemotaxis, invasion, and adhesion of human cancer cells. Neuropeptides 41: 441-452, 2007.
22. Nagakawa O, Ogasawara M, Fujii H, Murakami K, Murata J, Fuse H and Saiki I: Effect of prostatic neuropeptides on invasion and migration of PC-3 prostate cancer cells. Cancer Lett 133: 27-33, 1998.
23. Vermeulen SJ, Bruyneel EA, Bracke ME, De Bruyne GK, Vennekens KM, Vleminckx KL, Berx GJ, Van Roy FM and Mareel MM: Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells. Cancer Res 55: 4722-4728, 1995.
24. Mayer P, Tischmeyer H, Jayasinghe M, Bonnekoh B, Gollnick H, Teschemacher H and Hollt V: A delta opioid receptor lacking the third cytoplasmic loop is generated by atypical mRNA processing in human malignomas. FEBS Lett 480: 156-160, 2000.
25. Marie N, Lecoq I, Jauzac P and Allouche S: Differential sorting of human delta-opioid receptors after internalization by peptide and alkaloid agonists. J Biol Chem 278: 22795-22804, 2003.
26. Bracke ME, Boterberg T and Mareel MM: Chick heart invasion assay. In: Metastasis Research Protocols. Vol. 2. Cell Behavior In Vitro and In Vivo. Brooks SA and Schumacher U (eds.). Totowa, NJ, Humana Press, pp. 91-102, 2001
27. Gutstein HB, Rubie EA, Mansour A, Akil H and Woodgett JR: Opioid effects on mitogen-activated protein kinase signaling cascades. Anesthesiology 87: 1118-1126, 1997.
28. De Wever O, Hendrix A, De Boeck A, Westbroek W, Braems G, Emami S, Sabbah M, Gespach C and Bracke M: Modeling and quantification of cancer cell invasion through collagen type I matrices. Int J Dev Biol (in press).
29. Marchal JA, Boulaiz H, Suarez I, Saniger E, Campos J, Carrillo E, Prados J, Gallo MA, Espinosa A and Aranega A: Growth inhibition, G(1)-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives. Invest New Drugs 22: 379-389, 2004.
30. Behrens J, Mareel MM, Van Roy FM and Birchmeier W: Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol 108: 2435-2447, 1989.
31. Davies G, Jiang WG and Mason MD: Matrilysin mediates extracellular cleavage of E-cadherin from prostate cancer cells: a key mechanism in hepatocyte growth factor/scatter factor-induced cell-cell dissociation and in vitro invasion. Clin Cancer Res 7: 3289-3297, 2001.
32. Ogasawara M and Suzuki H: Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells. Biol Pharm Bull 27: 578-582, 2004.
33. Nylund G, Pettersson A, Bengtsson C, Khorram-Manesh A, Nordgren S and Delbro DS: Functional expression of mu-opioid receptors in the human colon cancer cell line, HT-29, and their localization in human colon. Dig Dis Sci 53: 461-466, 2008.
34. Hytrek SD, Smith JP, McGarrity TJ, McLaughlin PJ, Lang CM and Zagon IS: Identification and characterization of zeta-opioid receptor in human colon cancer. Am J Physiol 271: R115-R121, 1996.
35. Vermeulen SJ, Debruyne PR, Marra G, Speleman FP, Boukamp P, Jiricny J, Cuthbert AP, Newbold RF, Nollet FH, Van Roy FM and Mareel MM: hMSH6 deficiency and inactivation of the alphaE-catenin invasion-suppressor gene in HCT-8 colon cancer cells. Clin Exp Metastasis 17: 663-668, 1999.
36. Pineyro G and rcher-Lahlou E: Ligand-specific receptor states: implications for opiate receptor signalling and regulation. Cell Signal 19: 8-19, 2007.
37. Connor M and Christie MD: Opioid receptor signalling mechanisms. Clin Exp Pharmacol Physiol 26: 493-499, 1999.
38. Tegeder I and Geisslinger G: Opioids as modulators of cell death and survival - unraveling mechanisms and revealing new indications. Pharmacol Rev 56: 351-369, 2004.
39. Debruyne D, Mareel M, Vanhoecke B and Bracke M: Cell aggregation on agar as an indicator for cell-matrix adhesion: effects of opioids. In Vitro Cell Dev Biol Anim 45: 473-482, 2009.