Promotion of β-cell differentiation by the alkaloid conophylline in porcine pancreatic endocrine cells

Biomedicine and Pharmacotherapy

Volumn 64, Issue 3, 2010, Pages 226-231

  Kawakami, M ^a   Hirayama, A ^a   Tsuchiya, K ^b   Ohgawara, H ^b   Nakamura, M ^c   Umezawa, K ^a  

^a KEIO UNIVERSITY   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Conophylline; Diabetes mellitus; Insulin; Islet like cell clusters; Nicotinamide; Porcine pancreas

Indexed keywords

CONOPHYLLINE; GLUCOSE; INSULIN; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; NICOTINAMIDE; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; VINCA ALKALOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL REGENERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG SENSITIVITY; DRUG STRUCTURE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MONOLAYER CULTURE; NEWBORN; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ANALYSIS; SWINE;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; GENE EXPRESSION REGULATION; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; MOLECULAR STRUCTURE; NIACINAMIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUS SCROFA; SWINE; VINCA ALKALOIDS;

EID: 77649238968     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2009.09.025     Document Type: Article

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