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Volumn 37, Issue 5, 2009, Pages 1396-1410

Conversion from cyclosporin A to sirolimus retards the progression of chronic allograft nephropathy in the long term in a rat kidney transplantation model

Author keywords

Calcineurin inhibitors; Chronic allograft nephropathy; Cyclosporin A; Rapamycin; Rat kidney transplantation model; Sirolimus

Indexed keywords

CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; MESSENGER RNA; RAPAMYCIN;

EID: 77649222583     PISSN: 03000605     EISSN: 14732300     Source Type: Journal    
DOI: 10.1177/147323000903700514     Document Type: Article
Times cited : (1)

References (42)
  • 1
    • 33748286715 scopus 로고    scopus 로고
    • Longitudinal analysis of chronic allograft nephropathy: Clinicopathologic correlations
    • Chapman JR: Longitudinal analysis of chronic allograft nephropathy: clinicopathologic correlations. Kidney Int Suppl 2005; 68: S108-S112.
    • (2005) Kidney Int Suppl , vol.68
    • Chapman, J.R.1
  • 2
    • 0032946290 scopus 로고    scopus 로고
    • Rethinking chronic allograft nephropathy: The concept of accelerated senescence
    • Halloran PF, Melk A, Barth C: Rethinking chronic allograft nephropathy: the concept of accelerated senescence. J Am Soc Nephrol 1999; 10: 167-181.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 167-181
    • Halloran, P.F.1    Melk, A.2    Barth, C.3
  • 3
    • 0037979128 scopus 로고    scopus 로고
    • Pathogenesis of chronic allograft rejection
    • Joosten SA, van Kooten C, Paul LC: Pathogenesis of chronic allograft rejection. Transpl Int 2003; 16: 137-145.
    • (2003) Transpl Int , vol.16 , pp. 137-145
    • Joosten, S.A.1    van Kooten, C.2    Paul, L.C.3
  • 4
    • 0344666767 scopus 로고    scopus 로고
    • The natural history of chronic allograftnephropathy
    • Nankivell BJ, Borrows RJ, Fung CL, et al: The natural history of chronic allograftnephropathy. N Engl J Med 2003; 349: 2326-2333.
    • (2003) N Engl J Med , vol.349 , pp. 2326-2333
    • Nankivell, B.J.1    Borrows, R.J.2    Fung, C.L.3
  • 5
    • 0034671108 scopus 로고    scopus 로고
    • Impact of immunosuppressive therapy on hypertension
    • MacDonald AS: Impact of immunosuppressive therapy on hypertension. Transplantation 2000; 70 (11 suppl): S70-S76.
    • (2000) Transplantation , vol.70 , Issue.11 SUPPL.
    • Macdonald, A.S.1
  • 6
    • 0037297155 scopus 로고    scopus 로고
    • Diabetes mellitus after kidney transplantation in the United States
    • Kasiske BL, Snyder JJ, Gilbertson D, et al: Diabetes mellitus after kidney transplantation in the United States. Am J Transplant 2003; 3: 178-185.
    • (2003) Am J Transplant , vol.3 , pp. 178-185
    • Kasiske, B.L.1    Snyder, J.J.2    Gilbertson, D.3
  • 7
    • 1942502227 scopus 로고    scopus 로고
    • Withdrawal of cyclosporine or tacrolimus after addition of mycophenolate mofetil in patients with chronic allograft nephropathy
    • Suwelack B, Gerhardt U, Hohage H: Withdrawal of cyclosporine or tacrolimus after addition of mycophenolate mofetil in patients with chronic allograft nephropathy. Am J Transplant 2004; 4: 655-662.
    • (2004) Am J Transplant , vol.4 , pp. 655-662
    • Suwelack, B.1    Gerhardt, U.2    Hohage, H.3
  • 8
    • 4644277373 scopus 로고    scopus 로고
    • Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function
    • Weir MR, Blahut S, Drachenburg C, et al: Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. Am J Nephrol 2004; 24: 379-386.
    • (2004) Am J Nephrol , vol.24 , pp. 379-386
    • Weir, M.R.1    Blahut, S.2    Drachenburg, C.3
  • 9
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
    • Chung J, Kuo CJ, Crabtree GR, et al: Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 1992; 69: 1227-1236.
    • (1992) Cell , vol.69
    • Chung, J.1    Kuo, C.J.2    Crabtree, G.R.3
  • 10
    • 0026759874 scopus 로고
    • Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
    • Price DJ, Grove JR, Calvo V, et al: Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science 1992; 257: 973-977.
    • (1992) Science , vol.257 , pp. 973-977
    • Price, D.J.1    Grove, J.R.2    Calvo, V.3
  • 11
    • 0028172867 scopus 로고
    • Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin
    • Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature 1994; 372: 570-573.
    • (1994) Nature , vol.372 , pp. 570-573
    • Nourse, J.1    Firpo, E.2    Flanagan, W.M.3
  • 12
    • 0034721757 scopus 로고    scopus 로고
    • Conversion to rapamycin immunosuppression in renal transplant recipients: Report of an initial experience
    • Dominguez J, Mahalati K, Kiberd B, et al: Conversion to rapamycin immunosuppression in renal transplant recipients: report of an initial experience. Transplantation 2000; 70: 1244-1247.
    • (2000) Transplantation , vol.70 , pp. 1244-1247
    • Dominguez, J.1    Mahalati, K.2    Kiberd, B.3
  • 13
    • 0038298952 scopus 로고    scopus 로고
    • Conversion to sirolimus in solid organ transplantation: A single-center experience
    • Egidi MF, Cowan PA, Naseer A, et al: Conversion to sirolimus in solid organ transplantation: a single-center experience. Transplant Proc 2003; 35(3 suppl): 131S-137S.
    • (2003) Transplant Proc , vol.35 , Issue.3 SUPPL.
    • Egidi, M.F.1    Cowan, P.A.2    Naseer, A.3
  • 14
    • 27644439969 scopus 로고    scopus 로고
    • Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus
    • Bumbea V, Kamar N, Ribes D, et al: Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus. Nephrol Dial Transplant 2005; 20: 2517-2523.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 2517-2523
    • Bumbea, V.1    Kamar, N.2    Ribes, D.3
  • 15
    • 33644694497 scopus 로고    scopus 로고
    • A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation
    • Watson CJ, Firth J, Williams PF, et al: A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation. Am J Transplant 2005; 5: 2496-2503.
    • (2005) Am J Transplant , vol.5 , pp. 2496-2503
    • Watson, C.J.1    Firth, J.2    Williams, P.F.3
  • 16
    • 0026660308 scopus 로고
    • Progressive albuminuria and glomerulosclerosis in a rat model of chronic renal allograft rejection
    • Diamond JR, Tilney NL, Frye J, et al: Progressive albuminuria and glomerulosclerosis in a rat model of chronic renal allograft rejection. Transplantation 1992; 54: 710-716.
    • (1992) Transplantation , vol.54 , pp. 710-716
    • Diamond, J.R.1    Tilney, N.L.2    Frye, J.3
  • 17
    • 0027428113 scopus 로고
    • Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts
    • Hancock WH, Whitley WD, Tullius SG, et al: Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts. Transplantation 1993; 56: 643-650.
    • (1993) Transplantation , vol.56 , pp. 643-650
    • Hancock, W.H.1    Whitley, W.D.2    Tullius, S.G.3
  • 18
    • 0029907183 scopus 로고    scopus 로고
    • Therapeutic blood levels of sirolimus (rapamycin) in the allografted rat
    • DiJoseph JF, Fluhler E, Armstrong J, et al: Therapeutic blood levels of sirolimus (rapamycin) in the allografted rat. Transplantation 1996; 62: 1109-1112.
    • (1996) Transplantation , vol.62 , pp. 1109-1112
    • Dijoseph, J.F.1    Fluhler, E.2    Armstrong, J.3
  • 19
    • 0037096660 scopus 로고    scopus 로고
    • Tacrolimus and cyclosporine differ in their capacity to overcome ongoing allograft rejection as a result of their differential abilities to inhibit interleukin-10 production
    • Jiang H, Wynn C, Pan F, et al: Tacrolimus and cyclosporine differ in their capacity to overcome ongoing allograft rejection as a result of their differential abilities to inhibit interleukin-10 production. Transplantation 2002; 73: 1808-1817.
    • (2002) Transplantation , vol.73 , pp. 1808-1817
    • Jiang, H.1    Wynn, C.2    Pan, F.3
  • 20
    • 34147139494 scopus 로고    scopus 로고
    • The effect of FK778 on the progression of chronic allograft nephropathy in a rat model
    • Lutz J, Huang H, Deng M, et al: The effect of FK778 on the progression of chronic allograft nephropathy in a rat model. Transplantation 2007; 83: 741-746.
    • (2007) Transplantation , vol.83 , pp. 741-746
    • Lutz, J.1    Huang, H.2    Deng, M.3
  • 21
    • 0032910625 scopus 로고    scopus 로고
    • The Banff 97 working classification of renal allograft pathology
    • Racusen LC, Solez K, Colvin RB, et al: The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713-723.
    • (1999) Kidney Int , vol.55 , pp. 713-723
    • Racusen, L.C.1    Solez, K.2    Colvin, R.B.3
  • 22
    • 4143078169 scopus 로고    scopus 로고
    • Acute nephrotoxicity of tacrolimus and sirolimus in renal isografts: Differential intragraft expression of transforming growth factor-β1 and α-smooth muscle actin
    • Ninova D, Covarrubias M, Rea DJ, et al: Acute nephrotoxicity of tacrolimus and sirolimus in renal isografts: differential intragraft expression of transforming growth factor-β1 and α-smooth muscle actin. Transplantation 2004; 78: 338-344.
    • (2004) Transplantation , vol.78 , pp. 338-344
    • Ninova, D.1    Covarrubias, M.2    Rea, D.J.3
  • 23
    • 0015584206 scopus 로고
    • Arterial intimal thickening produced by alloantibody and xenoantibody
    • O'Connell TX, Mowbray JF: Arterial intimal thickening produced by alloantibody and xenoantibody. Transplantation 1973; 15: 262-263.
    • (1973) Transplantation , vol.15 , pp. 262-263
    • O'Connell, T.X.1    Mowbray, J.F.2
  • 24
    • 0036941129 scopus 로고    scopus 로고
    • The involvement of activated T cells and growth-factor production in the early and late phase of chronic kidney allograft nephropathy in rats
    • Hamar P, Szab A, Müller V, et al: The involvement of activated T cells and growth-factor production in the early and late phase of chronic kidney allograft nephropathy in rats. Transpl Int 2002; 15: 446-454.
    • (2002) Transpl Int , vol.15 , pp. 446-454
    • Hamar, P.1    Szab, A.2    Müller, V.3
  • 25
    • 0034863150 scopus 로고    scopus 로고
    • Combined treatment with mycophenolate mofetil and an angiotensin II receptor antagonist fully protects from chronic rejection in a rat model of renal allograft
    • Noris M, Azzollini N, Pezzotta A, et al: Combined treatment with mycophenolate mofetil and an angiotensin II receptor antagonist fully protects from chronic rejection in a rat model of renal allograft. J Am Soc Nephrol 2001; 12: 1937-1946.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1937-1946
    • Noris, M.1    Azzollini, N.2    Pezzotta, A.3
  • 26
    • 0034055332 scopus 로고    scopus 로고
    • SDZ-RAD prevents manifestation of chronic rejection in rat renal allografts
    • Viklický O, Zou H, Müller V, et al: SDZ-RAD prevents manifestation of chronic rejection in rat renal allografts. Transplantation 2000; 69: 497-502.
    • (2000) Transplantation , vol.69 , pp. 497-502
    • Viklický, O.1    Zou, H.2    Müller, V.3
  • 27
    • 0028841260 scopus 로고
    • Rapamycin inhibits transplant vasculopathy in long-surviving rat heart allografts
    • Schmid C, Heemann U, Azuma H, et al: Rapamycin inhibits transplant vasculopathy in long-surviving rat heart allografts. Transplantation 1995; 60: 729-733.
    • (1995) Transplantation , vol.60 , pp. 729-733
    • Schmid, C.1    Heemann, U.2    Azuma, H.3
  • 28
    • 0026328030 scopus 로고
    • Rapamycin inhibits spontaneous and fibroblast growth factor B-stimulated proliferation of endothelial cells and fibroblasts
    • Akselband Y, Harding MW, Nelson PA: Rapamycin inhibits spontaneous and fibroblast growth factor B-stimulated proliferation of endothelial cells and fibroblasts. Transplant Proc 1991; 23: 2833-2836.
    • (1991) Transplant Proc , vol.23 , pp. 2833-2836
    • Akselband, Y.1    Harding, M.W.2    Nelson, P.A.3
  • 29
    • 0028876806 scopus 로고
    • Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells
    • Marx SO, Jayaraman T, Go L, et al: Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells. Circ Res 1995; 76: 412-417.
    • (1995) Circ Res , vol.76 , pp. 412-417
    • Marx, S.O.1    Jayaraman, T.2    Go, L.3
  • 30
    • 0030756152 scopus 로고    scopus 로고
    • Different inhibitory effects of immunosuppressive drugs on human and rat aortic smooth muscle and endothelial cell proliferation stimulated by platelet-derived growth factor or endothelial cell growth factor
    • Mohacsi PJ, Tuller D, Hullinger B, et al: Different inhibitory effects of immunosuppressive drugs on human and rat aortic smooth muscle and endothelial cell proliferation stimulated by platelet-derived growth factor or endothelial cell growth factor. J Heart Lung Transplant 1997; 16: 484-492.
    • (1997) J Heart Lung Transplant , vol.16 , pp. 484-492
    • Mohacsi, P.J.1    Tuller, D.2    Hullinger, B.3
  • 31
    • 0033057120 scopus 로고    scopus 로고
    • SDZ RAD inhibits cold ischemia-induced vascular remodeling
    • Schuurman HJ, Pally C, Weckbecker G, et al: SDZ RAD inhibits cold ischemia-induced vascular remodeling. Transplant Proc 1999; 31: 1024-1025.
    • (1999) Transplant Proc , vol.31 , pp. 1024-1025
    • Schuurman, H.J.1    Pally, C.2    Weckbecker, G.3
  • 32
    • 0029909655 scopus 로고    scopus 로고
    • Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB)
    • Somasundaram R, Schuppan D: Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB). J Biol Chem 1996; 271: 26884-26891.
    • (1996) J Biol Chem , vol.271 , pp. 26884-26891
    • Somasundaram, R.1    Schuppan, D.2
  • 33
    • 0029853712 scopus 로고    scopus 로고
    • Expression of TGF-β1 and matrix proteins is elevated in rats with chronic rejection
    • Shihab FS, Tanner AM, Shao Y, et al: Expression of TGF-β1 and matrix proteins is elevated in rats with chronic rejection. Kidney Int 1996; 50: 1904-1913.
    • (1996) Kidney Int , vol.50 , pp. 1904-1913
    • Shihab, F.S.1    Tanner, A.M.2    Shao, Y.3
  • 34
    • 0032894729 scopus 로고    scopus 로고
    • Chronic rejection of mouse kidney allografts
    • Mannon RB, Kopp JB, Ruiz P, et al: Chronic rejection of mouse kidney allografts. Kidney Int 1999; 55: 1935-1944.
    • (1999) Kidney Int , vol.55 , pp. 1935-1944
    • Mannon, R.B.1    Kopp, J.B.2    Ruiz, P.3
  • 35
    • 0031011375 scopus 로고    scopus 로고
    • Myofibroblast phenotypes expression in experimental renal scarring
    • Muchaneta-Kubara EC, el Nahas AM: Myofibroblast phenotypes expression in experimental renal scarring. Nephrol Dial Transplant 1997; 12: 904-915.
    • (1997) Nephrol Dial Transplant , vol.12 , pp. 904-915
    • Muchaneta-Kubara, E.C.1    el Nahas, A.M.2
  • 36
    • 0028787493 scopus 로고
    • Regulation of transforming growth factor-β1 and its receptor by cyclosporine in human T lymphocytes
    • Ahuja SS, Shrivastav S, Danielpour D, et al: Regulation of transforming growth factor-β1 and its receptor by cyclosporine in human T lymphocytes. Transplantation 1995; 60: 718-723.
    • (1995) Transplantation , vol.60 , pp. 718-723
    • Ahuja, S.S.1    Shrivastav, S.2    Danielpour, D.3
  • 37
    • 0029145672 scopus 로고
    • Cyclosporine stimulates expression of transforming growth factor-β in renal cells. Possible mechanism of cyclosporines antiproliferative effects
    • Wolf G, Thaiss F, Stahl RA: Cyclosporine stimulates expression of transforming growth factor-β in renal cells. Possible mechanism of cyclosporines antiproliferative effects. Transplantation 1995; 60: 237-241.
    • (1995) Transplantation , vol.60 , pp. 237-241
    • Wolf, G.1    Thaiss, F.2    Stahl, R.A.3
  • 38
    • 0347382381 scopus 로고    scopus 로고
    • Mycophenolate mofetil ameliorates arteriolopathy and decreases transforming growth factor-β1 in chronic cyclosporine nephrotoxicity
    • Shihab FS, Bennett WM, Yi H, et al: Mycophenolate mofetil ameliorates arteriolopathy and decreases transforming growth factor-β1 in chronic cyclosporine nephrotoxicity. Am J Transplant 2003; 3: 1550-1559.
    • (2003) Am J Transplant , vol.3 , pp. 1550-1559
    • Shihab, F.S.1    Bennett, W.M.2    Yi, H.3
  • 39
    • 0034667761 scopus 로고    scopus 로고
    • Rapamycin induces transforming growth factor-β production by lymphocytes
    • Dodge IL, Demirci G, Strom TB, et al: Rapamycin induces transforming growth factor-β production by lymphocytes. Transplantation 2000; 70: 1104-1106.
    • (2000) Transplantation , vol.70 , pp. 1104-1106
    • Dodge, I.L.1    Demirci, G.2    Strom, T.B.3
  • 40
    • 1642356729 scopus 로고    scopus 로고
    • Combination therapy with sirolimus and mycophenolate mofetil: Effects on the kidney and on transforming growth factor-β1
    • Shihab FS, Bennett WM, Yi H, et al: Combination therapy with sirolimus and mycophenolate mofetil: effects on the kidney and on transforming growth factor-β1. Transplantation 2004; 77: 683-686.
    • (2004) Transplantation , vol.77 , pp. 683-686
    • Shihab, F.S.1    Bennett, W.M.2    Yi, H.3
  • 41
    • 0034594881 scopus 로고    scopus 로고
    • Improved graft survival after renal transplantation in the United States, 1988 to 1996
    • Hariharan S, Johnson CP, Bresnahan BA, et al: Improved graft survival after renal transplantation in the United States, 1988 to 1996. N Engl J Med 2000; 342: 605-612.
    • (2000) N Engl J Med , vol.342 , pp. 605-612
    • Hariharan, S.1    Johnson, C.P.2    Bresnahan, B.A.3
  • 42
    • 33645945017 scopus 로고    scopus 로고
    • Rapamycin for treatment of chronic allograft nephropathy in renal transplant patiens
    • Stallone G, Infante B, Schena A, et al: Rapamycin for treatment of chronic allograft nephropathy in renal transplant patiens. J Am Soc Nephrol 2005; 16: 3755-3762.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3755-3762
    • Stallone, G.1    Infante, B.2    Schena, A.3


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