Characterization of pH-responsive hydrogels of poly(itaconic acid-g-ethylene glycol) prepared by UV-initiated free radical polymerization as biomaterials for oral delivery of bioactive agents

Journal of Biomedical Materials Research - Part A

Volumn 93, Issue 1, 2010, Pages 175-188

  Betancourt, Tania ^a   Pardo, Juan ^a   Soo, Ken ^a   Peppas, Nicholas A ^a,b  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Biocompatibility; Caco 2 cells; Hydrogels; Itaconic acid; Poly(ethylene glycol)

Indexed keywords

BIOACTIVE AGENTS; CACO-2 CELLS; CARBOXYL GROUPS; CARBOXYLIC ACID GROUPS; CHARGE REPULSION; COLORECTAL CARCINOMA; CROSS LINKING AGENTS; CROSSLINKING RATIO; CYTOCOMPATIBILITY; EQUILIBRIUM SWELLING; GASTROINTESTINAL TRACT; HYDROGEN BONDINGS; ITACONIC ACID; MONOMER RATIO; ORAL DELIVERY; ORAL DRUG DELIVERY; PH GRADIENTS; PH RANGE; PH-RESPONSIVE; PH-RESPONSIVE HYDROGELS; POLY(ITACONIC ACID); PROTEOLYTIC ENZYME; TETRAETHYLENE GLYCOLS;

ATOM TRANSFER RADICAL POLYMERIZATION; BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; CARBOXYLIC ACIDS; CROSSLINKING; DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FREE RADICAL POLYMERIZATION; FREE RADICALS; HYDROGEN BONDS; ORGANIC ACIDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PROTEINS; SWELLING;

HYDROGELS;

BIOMATERIAL; CARBOXYL GROUP; ITACONIC ACID; MACROGOL; MONOMER; POLY(ITACONIC ACID G ETHYLENE GLYCOL); POLYMER; UNCLASSIFIED DRUG;

ACIDITY; ALKALINITY; ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; CELL STRAIN CACO 2; CHEMICAL COMPOSITION; COLORECTAL CANCER; CROSS LINKING; DRUG DELIVERY SYSTEM; HYDROGEL; HYDROGEN BOND; INFRARED SPECTROSCOPY; NONHUMAN; PH; POLYMERIZATION; SURFACE PROPERTY; SWELLING; ULTRAVIOLET RADIATION;

ADMINISTRATION, ORAL; BIOCOMPATIBLE MATERIALS; CACO-2 CELLS; CELL DEATH; CELL SURVIVAL; CROSS-LINKING REAGENTS; DRUG DELIVERY SYSTEMS; FREE RADICALS; HUMANS; HYDROGELS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR WEIGHT; PARTICLE SIZE; POLYETHYLENE GLYCOLS; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUCCINATES; ULTRAVIOLET RAYS;

EID: 77649216630     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32510     Document Type: Article

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