Danggui-Shaoyao-San and its active fraction JD-30 improve Aβ-induced spatial recognition deficits in mice

Journal of Ethnopharmacology

Volumn 128, Issue 2, 2010, Pages 365-372

  Hu, Zeng Yao ^a   Liu, Gang ^a   Yuan, Hui ^a   Yang, Sheng ^a   Zhou, Wen Xia ^a   Zhang, Yong Xiang ^a   Qiao, Shan Yi ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Amyloid; Danggui Shaoyao San; Fibril formation; JD 30; Long term potentiation; Spatial learning and memory

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[25-35]; JD 30; PLANT EXTRACT; TOKISHAKUYAKU SAN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG ISOLATION; ELECTRON MICROSCOPY; FIBER; HIPPOCAMPUS; LEARNING; LONG TERM POTENTIATION; MALE; MAZE TEST; MEMORY DISORDER; MICROELECTRODE; MOUSE; NONHUMAN; PROTEIN AGGREGATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; COGNITION; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; HIPPOCAMPUS; HUMANS; LEARNING; LONG-TERM POTENTIATION; MALE; MEMORY; MICE; MICE, INBRED STRAINS; RANDOM ALLOCATION; RECEPTORS, CELL SURFACE;

DANGGUI; MUS;

EID: 77649193490     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.01.046     Document Type: Article

References (29)

1. Aisen P.S. The development of anti-amyloid therapy for Alzheimer's disease from secretase modulators to polymerisation inhibitors. CNS Drugs 19 (2005) 989-996
2. Bliss T.V., and Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361 (1993) 31-39
3. Bliss T.V., and Lomo T. Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. The Journal of Physiology 232 (1973) 331-356
4. Chen L.L., Qi J., Chang Y.X., Zhu D.N., and Yu B.Y. Identification and determination of the major constituents in traditional Chinese medicinal formula Danggui-shaoyao-san by HPLC-DAD-ESI-MS/MS. Journal of Pharmaceutical and Biomedical Analysis 77 (2009) 127-137
5. Cummings J.L. Alzheimer's disease. The New England Journal of Medicine 351 (2004) 56-67
6. Dall'Igna O.P., Fett P., Gomes M.W., Souza D.O., Cunha R.A., and Lara D.R. Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice. Experimental Neurology 203 (2007) 241-245
7. Delobette S., Privat A., and Maurice T. In vitro aggregation facilities beta-amyloid peptide-(25-35)-induced amnesia in the rat. European Journal of Pharmacology 319 (1997) 1-4
8. D'Hooge R., and De Deyn P.P. Applications of the Morris water maze in the study of learning and memory. Brain Research. Brain Research Reviews 36 (2001) 60-90
9. Egashira N., Iwasaki K., Akiyoshi Y., Takagaki Y., Hatip-Al-Khatib I., Mishima K., Kurauchi K., Ikeda T., and Fujiwara M. Protective effect of Toki-shakuyaku-san on amyloid beta25-35-induced neuronal damage in cultured rat cortical neurons. Phytotherapy Research: PTR 19 (2005) 450-453
10. Fu A.L., Dong Z.H., and Sun M.J. Protective effect of N-acetyl-l-cysteine on amyloid beta-peptide-induced learning and memory deficits in mice. Brain Research 1109 (2006) 201-206
11. Fujii T. Herbal factors in the treatment of autoimmunity-related habitual abortion. Vitamins and Hormones 65 (2002) 333-344
12. Hagino N. An overview of Kampo Medicine: Toki-Shakuyaku-San (TJ-23). Phytotherapy Research: PTR 7 (1994) 391-394
13. Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 (2002) 353-356
14. Hatip-Al-Khatib I., Egashira N., Mishima K., Iwasaki K., Iwasaki K., Kurauchi K., Imui K., Ikeda T., and Fujiwara M. Determination of the effectiveness of components of the herbal medicine Toki-Shakuyaku-San and fractions of Angelica acutiloba in improving the scopolamine-induced impairment of rat's spatial cognition in eight-armed radial maze test. Journal of Pharmacological Sciences 96 (2004) 33-41
15. Higaki S., Toyomoto T., and Morohashi M. Seijo-bofu-to, Jumi-haidoku-to and Toki-shakuyaku-san suppress rashes and incidental symptoms in acne patients. Drugs under Experimental and Clinical Research 28 (2002) 193-196
16. Howes M.J., and Houghton P.J. Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function. Pharmacology, Biochemistry, and Behavior 75 (2003) 513-527
17. Hu Z.Y., Yang Y., Zhou W.X., Zhang Y.X., Shang W.W., and Qiao S.Y. JD-30, an active constituent extracted from Danggui Shaoyao San, ameliorates amyloid beta-protein fragment 25-35 induced inhibition of long-term potentiation of CA1 area in rat hippocampal slices. Chinese Journal of Pharmacology and Toxicology 21 (2007) 185-189
18. Inanaga K. Aging in brain and mind-drug therapy for patients with behavioral and psychological symptoms of dementia (BPSD). Seishin Shinkeigaku Zasshi 109 (2007) 703-708
19. Itoh T., Michijiri S., Murai S., Saito H., Nakamura K., Itsukaichi O., Fujiwara H., Ookubo N., and Saito H. Regulatory effect of danggui-shaoyao-san on central cholinergic nervous system dysfunction in mice. The American Journal of Chinese Medicine 24 (1996) 205-217
20. Kitabayashi Y., Shibata K., Nakamae T., Narumoto J., and Fukui K. Effect of traditional Japanese herbal medicine toki-shakuyaku-san for mild cognitive impairment: SPECT study. Psychiatry and Clinical Neurosciences 61 (2007) 447-448
21. Kotani N., Oyama T., Sakai I., Hashimoto H., Muraoka M., Ogawa Y., and Matsuki A. Analgesic effect of a herbal medicine for treatment of primary dysmenorrhea-a double-blind study. The American Journal of Chinese Medicine 25 (1997) 205-212
22. Li Z.L., Xie Y., Xu X.W., Zhang Y.Y., and He H.W. Danggui Shaoyao San inhibits amyloid-β 1-42 from aggregation and fibril formation in vitro. Anatomy Research 27 (2005) 263-267
23. Liao M.Q., Tzeng Y.J., Chang L.Y., Huang H.B., Lin T.H., Chyan C.L., and Chen Y.C. The correlation between neurotoxicity, aggregative ability and secondary structure studied by sequence truncated Abeta peptides. FEBS Letters 581 (2007) 1161-1165
24. Mizushima N. Effects of TJ-23 (Toki-shakuyaku-san) on senile dementia. Journal of Medical and Pharmaceutical Society for Wakan-Yaku 6 (1989) 456-457
25. Mizushima Y., Kan S., Yoshida S., Irie Y., and Urata Y. Effect of Choto-san, a Kampo medicine, on impairment of passive avoidance performance in senescence accelerated mouse (SAM). Phytotherapy Research: PTR 17 (2003) 542-545
26. Morris R.G. Elements of a neurobiological theory of hippocampal function: the role of synaptic plasticity, synaptic tagging and schemas. The European Journal of Neuroscience 23 (2006) 2829-2846
27. Pu F., Mishima K., Egashira N., Akiyoshi Y., Liu A.X., Sano K., Irie K., Ishibashi D., Hatip-Al-Khatib I., Iwasaki K., Kurauchi K., Iwasaki K., and Fujiwara M. Post-ischemic treatment with toki-shakuyaku-san (tang-gui-shao-yao-san) prevents the impairment of spatial memory induced by repeated cerebral ischemia in rats. The American Journal of Chinese Medicine 33 (2005) 475-489
28. Qiao H.F., Yang S., Zhou W.X., and Zhang Y.X. NT-1, an active constituent extracted from Tiaoxin Recipe, enhances long-term potentiation of CA1 subfield in rat hippocampal slices. Life Sciences 79 (2006) 8-15
29. Ueda Y., Komatsu M., and Hiramatsu M. Free radical scavenging activity of the Japanese herbal medicine toki-shakuyaku-san (TJ-23) and its effect on superoxide dismutase activity, lipid peroxides, glutamate, and monoamine metabolites in aged rat brain. Neurochemical Research 21 (1996) 909-914