메뉴 건너뛰기




Volumn 290, Issue 2, 2010, Pages 238-247

Upregulated fascin1 in non-small cell lung cancer promotes the migration and invasiveness, but not proliferation

Author keywords

Fascin1; Invasiveness; Migration; Non small cell lung cancer; Proliferation

Indexed keywords

ACTIN BINDING PROTEIN; FASCIN1; UNCLASSIFIED DRUG;

EID: 77649193089     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.09.013     Document Type: Article
Times cited : (45)

References (59)
  • 2
    • 0036893858 scopus 로고    scopus 로고
    • Consensus development conference on the medical treatment of non-small cell lung cancer: treatment of the early stages
    • Scagliotti G. Consensus development conference on the medical treatment of non-small cell lung cancer: treatment of the early stages. Lung Cancer 38 suppl. 3 (2002) S23-S29
    • (2002) Lung Cancer , vol.38 , Issue.SUPPL. 3
    • Scagliotti, G.1
  • 3
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: building a framework
    • Gupta G.P., and Massague J. Cancer metastasis: building a framework. Cell 127 (2006) 679-695
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 4
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion, migration: diversity and escape mechanisms
    • Friedl P., and Wolf K. Tumour-cell invasion, migration: diversity and escape mechanisms. Nat. Rev. Cancer 3 (2003) 362-374
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 5
    • 0037459075 scopus 로고    scopus 로고
    • Cellular motility driven by assembly and disassembly of actin filaments
    • Pollard T.D., and Borisy G.G. Cellular motility driven by assembly and disassembly of actin filaments. Cell 112 (2003) 453-465
    • (2003) Cell , vol.112 , pp. 453-465
    • Pollard, T.D.1    Borisy, G.G.2
  • 6
    • 4644346321 scopus 로고    scopus 로고
    • Fascin protrusions in cell interactions
    • Adams J.C. Fascin protrusions in cell interactions. Trends Cardiovas. Med. 14 (2004) 221-226
    • (2004) Trends Cardiovas. Med. , vol.14 , pp. 221-226
    • Adams, J.C.1
  • 7
    • 4444285120 scopus 로고    scopus 로고
    • Roles of fascin in cell adhesion and motility
    • Adams J.C. Roles of fascin in cell adhesion and motility. Curr. Opin. Cell Biol. 16 (2004) 590-596
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 590-596
    • Adams, J.C.1
  • 8
    • 0016537752 scopus 로고
    • Preparation and purification of polymerized actin from sea urchin egg extracts
    • Kane R.E. Preparation and purification of polymerized actin from sea urchin egg extracts. J. Cell Biol. 66 (1975) 305-315
    • (1975) J. Cell Biol. , vol.66 , pp. 305-315
    • Kane, R.E.1
  • 9
    • 21844439742 scopus 로고    scopus 로고
    • Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?
    • Hashimoto Y., Skacel M., and Adams J.C. Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?. Int. J. Biochem. Cell Biol. 37 (2005) 1787-1804
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 1787-1804
    • Hashimoto, Y.1    Skacel, M.2    Adams, J.C.3
  • 12
    • 67949106668 scopus 로고    scopus 로고
    • Cortactin, fascin, and survivin expression associated with clinicopathological parameters in esophageal squamous cell carcinoma
    • Hsu K.F., Lin C.K., Yu C.P., Tzao C., Lee S.C., Lee Y.Y., Tsai W.C., and Jin J.S. Cortactin, fascin, and survivin expression associated with clinicopathological parameters in esophageal squamous cell carcinoma. Dis. Esophagus. 22 (2009) 402-408
    • (2009) Dis. Esophagus. , vol.22 , pp. 402-408
    • Hsu, K.F.1    Lin, C.K.2    Yu, C.P.3    Tzao, C.4    Lee, S.C.5    Lee, Y.Y.6    Tsai, W.C.7    Jin, J.S.8
  • 13
    • 4444249228 scopus 로고    scopus 로고
    • The prognostic relevance of fascin expression in human gastric carcinoma
    • Hashimoto Y., Shimada Y., Kawamura J., Yamasaki S., and Imamura M. The prognostic relevance of fascin expression in human gastric carcinoma. Oncology 67 (2004) 262-270
    • (2004) Oncology , vol.67 , pp. 262-270
    • Hashimoto, Y.1    Shimada, Y.2    Kawamura, J.3    Yamasaki, S.4    Imamura, M.5
  • 15
    • 51049117743 scopus 로고    scopus 로고
    • Aberrant expression of cortactin and fascin are effective markers for pathogenesis, invasion, metastasis and prognosis of gastric carcinomas
    • Li X., Zheng H., Hara T., Takahashi H., Masuda S., Wang Z., Yang X., Guan Y., and Takano Y. Aberrant expression of cortactin and fascin are effective markers for pathogenesis, invasion, metastasis and prognosis of gastric carcinomas. Int. J. Oncol. 33 (2008) 69-79
    • (2008) Int. J. Oncol. , vol.33 , pp. 69-79
    • Li, X.1    Zheng, H.2    Hara, T.3    Takahashi, H.4    Masuda, S.5    Wang, Z.6    Yang, X.7    Guan, Y.8    Takano, Y.9
  • 18
    • 18444403112 scopus 로고    scopus 로고
    • Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47
    • Maitra A., Iacobuzio-Donahue C., Rahman A., Sohn T.A., Argani P., Meyer R., Yeo C.J., Cameron J.L., Goggins M., Kern S.E., Ashfaq R., Hruban R.H., and Wilentz R.E. Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47. Am. J. Clin. Pathol. 118 (2002) 52-59
    • (2002) Am. J. Clin. Pathol. , vol.118 , pp. 52-59
    • Maitra, A.1    Iacobuzio-Donahue, C.2    Rahman, A.3    Sohn, T.A.4    Argani, P.5    Meyer, R.6    Yeo, C.J.7    Cameron, J.L.8    Goggins, M.9    Kern, S.E.10    Ashfaq, R.11    Hruban, R.H.12    Wilentz, R.E.13
  • 19
    • 34247328661 scopus 로고    scopus 로고
    • Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade
    • Yamaguchi H., Inoue T., Eguchi T., Miyasaka Y., Ohuchida K., Mizumoto K., Yamada T., Yamaguchi K., Tanaka M., and Tsuneyoshi M. Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade. Mod. Pathol. 20 (2007) 552-561
    • (2007) Mod. Pathol. , vol.20 , pp. 552-561
    • Yamaguchi, H.1    Inoue, T.2    Eguchi, T.3    Miyasaka, Y.4    Ohuchida, K.5    Mizumoto, K.6    Yamada, T.7    Yamaguchi, K.8    Tanaka, M.9    Tsuneyoshi, M.10
  • 20
    • 11344285907 scopus 로고    scopus 로고
    • The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course
    • Yoder B.J., Tso E., Skacel M., Pettay J., Tarr S., Budd T., Tubbs R.R., Adams J.C., and Hicks D.G. The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course. Clin. Cancer Res. 11 (2005) 186-192
    • (2005) Clin. Cancer Res. , vol.11 , pp. 186-192
    • Yoder, B.J.1    Tso, E.2    Skacel, M.3    Pettay, J.4    Tarr, S.5    Budd, T.6    Tubbs, R.R.7    Adams, J.C.8    Hicks, D.G.9
  • 22
    • 45949084988 scopus 로고    scopus 로고
    • Prognostic significance of fascin expression in advanced poorly differentiated serous ovarian cancer
    • Daponte A., Kostopoulou E., Minas M., Koukoulis G., and Messinis I.E. Prognostic significance of fascin expression in advanced poorly differentiated serous ovarian cancer. Anticancer Res. 28 (2008) 1905-1910
    • (2008) Anticancer Res. , vol.28 , pp. 1905-1910
    • Daponte, A.1    Kostopoulou, E.2    Minas, M.3    Koukoulis, G.4    Messinis, I.E.5
  • 23
    • 68949199565 scopus 로고    scopus 로고
    • Fascin expression in serous tumors of ovary correlates with aggressiveness of malignancy
    • Wen Y.H., Yee H., Goswami S., and Shukla P.S. Fascin expression in serous tumors of ovary correlates with aggressiveness of malignancy. Int. J. Gynecol. Pathol. 28 (2009) 187-192
    • (2009) Int. J. Gynecol. Pathol. , vol.28 , pp. 187-192
    • Wen, Y.H.1    Yee, H.2    Goswami, S.3    Shukla, P.S.4
  • 24
    • 0035990482 scopus 로고    scopus 로고
    • Actin-binding protein fascin expression in skin neoplasia
    • Goncharuk V.N., Ross J.S., and Carlson J.A. Actin-binding protein fascin expression in skin neoplasia. J. Cutan. Pathol. 29 (2002) 430-438
    • (2002) J. Cutan. Pathol. , vol.29 , pp. 430-438
    • Goncharuk, V.N.1    Ross, J.S.2    Carlson, J.A.3
  • 29
    • 44849109087 scopus 로고    scopus 로고
    • Fascin expression [corrected] in glial tumors and its prognostic significance in glioblastomas
    • Gunal A., Onguru O., Safali M., and Beyzadeoglu M. Fascin expression [corrected] in glial tumors and its prognostic significance in glioblastomas. Neuropathology 28 (2008) 382-386
    • (2008) Neuropathology , vol.28 , pp. 382-386
    • Gunal, A.1    Onguru, O.2    Safali, M.3    Beyzadeoglu, M.4
  • 30
    • 39049136505 scopus 로고    scopus 로고
    • The role of fascin in the migration and invasiveness of malignant glioma cells
    • Hwang J.H., Smith C.A., Salhia B., and Rutka J.T. The role of fascin in the migration and invasiveness of malignant glioma cells. Neoplasia 10 (2008) 149-159
    • (2008) Neoplasia , vol.10 , pp. 149-159
    • Hwang, J.H.1    Smith, C.A.2    Salhia, B.3    Rutka, J.T.4
  • 31
    • 46249085706 scopus 로고    scopus 로고
    • Does the expression of fascin-1 and tumor subclassification help to assess the risk of recurrence and progression in t1 urothelial urinary bladder carcinoma?
    • Soukup V., Babjuk M., Duskova J., Pesl M., Szakaczova M., Zamecnik L., and Dvoracek J. Does the expression of fascin-1 and tumor subclassification help to assess the risk of recurrence and progression in t1 urothelial urinary bladder carcinoma?. Urol. Int. 80 (2008) 413-418
    • (2008) Urol. Int. , vol.80 , pp. 413-418
    • Soukup, V.1    Babjuk, M.2    Duskova, J.3    Pesl, M.4    Szakaczova, M.5    Zamecnik, L.6    Dvoracek, J.7
  • 34
    • 33746879171 scopus 로고    scopus 로고
    • Fascin immunoreactivity for preoperatively predicting lymph node metastases in peripheral adenocarcinoma of the lung 3 cm or less in diameter
    • Choi P.J., Yang D.K., Son C.H., Lee K.E., Lee J.I., and Roh M.S. Fascin immunoreactivity for preoperatively predicting lymph node metastases in peripheral adenocarcinoma of the lung 3 cm or less in diameter. Eur. J. Cardio - Thorac. Surg. 30 (2006) 538-542
    • (2006) Eur. J. Cardio - Thorac. Surg. , vol.30 , pp. 538-542
    • Choi, P.J.1    Yang, D.K.2    Son, C.H.3    Lee, K.E.4    Lee, J.I.5    Roh, M.S.6
  • 36
    • 34447124462 scopus 로고    scopus 로고
    • FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo
    • Adiseshaiah P., Lindner D.J., Kalvakolanu D.V., and Reddy S.P. FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo. Cancer Res. 67 (2007) 6204-6211
    • (2007) Cancer Res. , vol.67 , pp. 6204-6211
    • Adiseshaiah, P.1    Lindner, D.J.2    Kalvakolanu, D.V.3    Reddy, S.P.4
  • 37
    • 33750627650 scopus 로고    scopus 로고
    • Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas
    • Hashimoto Y., Skacel M., Lavery I.C., Mukherjee A.L., Casey G., and Adams J.C. Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas. BMC Cancer 6 (2006) 241
    • (2006) BMC Cancer , vol.6 , pp. 241
    • Hashimoto, Y.1    Skacel, M.2    Lavery, I.C.3    Mukherjee, A.L.4    Casey, G.5    Adams, J.C.6
  • 43
    • 0034609766 scopus 로고    scopus 로고
    • C-erbB-2/HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines
    • Grothey A., Hashizume R., Ji H., Tubb B.E., Patrick Jr. C.W., Yu D., Mooney E.E., and McCrea P.D. C-erbB-2/HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines. Oncogene 19 (2000) 4864-4875
    • (2000) Oncogene , vol.19 , pp. 4864-4875
    • Grothey, A.1    Hashizume, R.2    Ji, H.3    Tubb, B.E.4    Patrick Jr., C.W.5    Yu, D.6    Mooney, E.E.7    McCrea, P.D.8
  • 44
    • 0036218155 scopus 로고    scopus 로고
    • Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor
    • Guvakova M.A., Boettiger D., and Adams J.C. Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor. Int. J. Biochem. Cell Biol. 34 (2002) 685-698
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 685-698
    • Guvakova, M.A.1    Boettiger, D.2    Adams, J.C.3
  • 45
    • 0038798665 scopus 로고    scopus 로고
    • Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin
    • Shonukan O., Bagayogo I., McCrea P., Chao M., and Hempstead B. Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin. Oncogene 22 (2003) 3616-3623
    • (2003) Oncogene , vol.22 , pp. 3616-3623
    • Shonukan, O.1    Bagayogo, I.2    McCrea, P.3    Chao, M.4    Hempstead, B.5
  • 46
    • 0030949558 scopus 로고    scopus 로고
    • Ki67 labelling index in gastric carcinomas. An immunohistochemical study using double staining for the evaluation of the proliferative activity of diffuse-type carcinomas
    • Ramires M., David L., Leitao D., Seixas M., Sansonetty F., and Sobrinho-Simoes M. Ki67 labelling index in gastric carcinomas. An immunohistochemical study using double staining for the evaluation of the proliferative activity of diffuse-type carcinomas. J. Pathol. 182 (1997) 62-67
    • (1997) J. Pathol. , vol.182 , pp. 62-67
    • Ramires, M.1    David, L.2    Leitao, D.3    Seixas, M.4    Sansonetty, F.5    Sobrinho-Simoes, M.6
  • 47
    • 0035149139 scopus 로고    scopus 로고
    • The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation
    • Jung A., Schrauder M., Oswald U., Knoll C., Sellberg P., Palmqvist R., Niedobitek G., Brabletz T., and Kirchner T. The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation. Am. J. Pathol. 159 (2001) 1613-1617
    • (2001) Am. J. Pathol. , vol.159 , pp. 1613-1617
    • Jung, A.1    Schrauder, M.2    Oswald, U.3    Knoll, C.4    Sellberg, P.5    Palmqvist, R.6    Niedobitek, G.7    Brabletz, T.8    Kirchner, T.9
  • 49
    • 0033605134 scopus 로고    scopus 로고
    • Glucocorticoid down-regulation of fascin protein expression is required for the steroid-induced formation of tight junctions and cell-cell interactions in rat mammary epithelial tumor cells
    • Wong V., Ching D., McCrea P.D., and Firestone G.L. Glucocorticoid down-regulation of fascin protein expression is required for the steroid-induced formation of tight junctions and cell-cell interactions in rat mammary epithelial tumor cells. J. Biol. Chem. 274 (1999) 5443-5453
    • (1999) J. Biol. Chem. , vol.274 , pp. 5443-5453
    • Wong, V.1    Ching, D.2    McCrea, P.D.3    Firestone, G.L.4
  • 50
    • 0036346060 scopus 로고    scopus 로고
    • Transforming growth factor-alpha abrogates the glucocorticoid stimulation of tight junction formation and reverses the steroid-induced down-regulation of fascin in rat mammary epithelial tumor cells by a Ras-dependent pathway
    • Guan Y., Woo P.L., Rubenstein N.M., and Firestone G.L. Transforming growth factor-alpha abrogates the glucocorticoid stimulation of tight junction formation and reverses the steroid-induced down-regulation of fascin in rat mammary epithelial tumor cells by a Ras-dependent pathway. Exp. Cell Res. 273 (2002) 1-11
    • (2002) Exp. Cell Res. , vol.273 , pp. 1-11
    • Guan, Y.1    Woo, P.L.2    Rubenstein, N.M.3    Firestone, G.L.4
  • 51
    • 33646037353 scopus 로고    scopus 로고
    • Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene, BRMS1
    • Zhang S., Lin Q.D., and DI W. Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene, BRMS1. Int. J. Gynecol. Cancer 16 (2006) 522-531
    • (2006) Int. J. Gynecol. Cancer , vol.16 , pp. 522-531
    • Zhang, S.1    Lin, Q.D.2    DI, W.3
  • 52
    • 64549140740 scopus 로고    scopus 로고
    • Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells
    • Hashimoto Y., Loftis D.W., and Adams J.C. Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells. PLoS ONE 4 (2009) e5130
    • (2009) PLoS ONE , vol.4
    • Hashimoto, Y.1    Loftis, D.W.2    Adams, J.C.3
  • 53
    • 0142073731 scopus 로고    scopus 로고
    • Interaction of fascin and protein kinase C alpha: a novel intersection in cell adhesion and motility
    • Anilkumar N., Parsons M., Monk R., Ng T., and Adams J.C. Interaction of fascin and protein kinase C alpha: a novel intersection in cell adhesion and motility. EMBO J. 22 (2003) 5390-5402
    • (2003) EMBO J. , vol.22 , pp. 5390-5402
    • Anilkumar, N.1    Parsons, M.2    Monk, R.3    Ng, T.4    Adams, J.C.5
  • 55
    • 35848950225 scopus 로고    scopus 로고
    • Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis
    • Hashimoto Y., Parsons M., and Adams J.C. Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis. Mol. Biol. Cell 18 (2007) 4591-4602
    • (2007) Mol. Biol. Cell , vol.18 , pp. 4591-4602
    • Hashimoto, Y.1    Parsons, M.2    Adams, J.C.3
  • 56
    • 0034698675 scopus 로고    scopus 로고
    • Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42
    • Adams J.C., and Schwartz M.A. Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42. J. Cell Biol. 150 (2000) 807-822
    • (2000) J. Cell Biol. , vol.150 , pp. 807-822
    • Adams, J.C.1    Schwartz, M.A.2
  • 57
    • 53349097707 scopus 로고    scopus 로고
    • Rac regulates the interaction of fascin with protein kinase C in cell migration
    • Parsons M., and Adams J.C. Rac regulates the interaction of fascin with protein kinase C in cell migration. J. Cell Sci. 121 (2008) 2805-2813
    • (2008) J. Cell Sci. , vol.121 , pp. 2805-2813
    • Parsons, M.1    Adams, J.C.2
  • 59
    • 0032500661 scopus 로고    scopus 로고
    • Regulation of actin binding and actin bundling activities of fascin by caldesmon coupled with tropomyosin
    • Ishikawa R., Yamashiro S., Kohama K., and Matsumura F. Regulation of actin binding and actin bundling activities of fascin by caldesmon coupled with tropomyosin. J. Biol. Chem. 273 (1998) 26991-26997
    • (1998) J. Biol. Chem. , vol.273 , pp. 26991-26997
    • Ishikawa, R.1    Yamashiro, S.2    Kohama, K.3    Matsumura, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.