Fascins, and their roles in cell structure and function

BioEssays

Volumn 24, Issue 4, 2002, Pages 350-361

  Kureishy, Nina ^a,b   Sapountzi, Vasileia ^a   Prag, Soren ^a   Anilkumar, N ^a   Adams, Josephine Clare ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CARRIER PROTEIN; FASCIN;

ANIMAL; CELL; CELL ADHESION; CELL FUNCTION; CELL MOTION; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; HUMAN; PHYSIOLOGY; PROTEIN CONFORMATION; REVIEW;

ACTINS; ANIMALS; CARRIER PROTEINS; CELL ADHESION; CELL MOVEMENT; CELL PHYSIOLOGY; CELLS; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HUMANS; MICROFILAMENT PROTEINS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 0036010596     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.10070     Document Type: Review

References (91)

1. Separation and interaction of the major components of sea urchin actin gel
2. Formation of filopodia in coelomocytes: Localization of fascin, a 58,000 dalton actin cross-linking protein
3. A protein in starfish sperm head which bundles actin filaments in vitro: Purification and characterization
4. Structure and transcription of the singed locus of Drosophila melanogaster
5. Fascin, an echinoid actin-bundling protein, is a homolog of the Drosophila singed gene product
6. Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein
7. A vertebrate homolog of the actin-bundling protein fascin
8. cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein
9. Cloning and expression of a murine fascin homolog from mouse brain
10. Isolation of a cDNA encoding a photoreceptor cell-specific actin-bundling protein: Retinal fascin
11. Characterization of human retinal fascin gene (FSCN2) at 17q25: Close physical linkage of fascin and cytoplasmic actin genes
12. Retinal fascin: Functional nature, subcellular distribution, and chromosomal localization
13. The genome sequence of Drosophila melanogaster
14. Purification and characterization of an F-actin-bundling 55-kilodalton protein from HeLa cells
15. Identification of distant homologues of fibroblast growth factors suggests a common ancestor for all beta-trefoil proteins
16. Beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors
17. Three-dimensional structure of human basic fibroblast growth factor
18. Structure of interleukin 1 alpha at 2.7-A resolution
19. Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin
20. Cell-matrix adhesions differentially regulate fascin phosphorylation
21. Single amino acid mutations in Drosophila fascin disrupt actin bundling function in vivo
22. Phosphorylation of human fascin inhibits its actin binding and bundling activities
23. Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension
24. Fascins, a family of actin bundling proteins
25. Growth conditions control the size and order of actin bundles in vitro
26. Micromechanics and ultrastructure of actin filament networks crosslinked by human fascin: A comparison with alpha-actinin
27. Actin crosslinking proteins at the leading edge
28. The structure and function of alpha-actinin
29. Structure of the alpha-actinin rod: Molecular basis for cross-linking of actin filaments
30. The three-dimensional structure of alpha-actinin obtained by cryoelectron microscopy suggests a model for Ca(2+)-dependent actin binding
31. Structural and functional aspects of filamins
32. Morphogenesis of liposomes encapsulating actin depends on the type of actin-cross-linking
33. Multiple-particle tracking measurements of heterogeneities in solutions of actin filaments and actin bundles
34. Actin in the photoreceptor connecting cilium: Immunocytochemical localization to the site of outer segment disk formation
35. Formation of stable microspikes containing actin and the 55 kDa actin bundling protein, fascin, is a consequence of cell adhesion to thrombospondin-1: Implications for the anti-adhesive activities of thrombospondin-1
36. Characterization of cell-matrix adhesion requirements for the formation of fascin microspikes
37. A role for syndecan-1 in coupling fascin spike formation by thrombospondin-1
38. Intracellular localization of the 55-kD actin-bundling protein in cultured cells: Spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin
39. Beta-Catenin associates with the actin-bundling protein fascin in a non-cadherin complex
40. Glucocorticoid down-regulation of fascin protein expression is required for the steroid-induced formation of tight junctions and cell-cell interactions in rat mammary epithelial tumor ceils
41. Inhibition by drebrin of the actin-bundling activity of brain fascin, a protein localized in filopodia of growth cones
42. Redistribution of actin and fascin in sea urchin eggs after fertilization
43. Role of the actin bundling protein fascin in growth cone morphogenesis: Localization in filopodia and lamellipodia
44. Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells
45. C-erbB-2/HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines
46. Integrin alpha3beta1 engagement disrupts intercellular adhesion
47. Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42
48. Cell-adhesive responses to tenascin-C splice variants involve formation of fascin microspikes
49. p120 catenin affects cell motility via modulation of activity of Rho-famity GTPases: A link between cell-cell contact formation and regulation of cell locomotion
50. Actin machinery: Pushing the envelope
51. Invited Review: Cross-bridge regulation by thin filament-associated proteins
52. Visualization of caldesmon on smooth muscle thin filaments
53. Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions
54. Regulation of actin binding and actin bundling activities of fascin by caldesmon coupled with tropomyosin
55. Monoclonal antibodies against caldesmon, a Ca++/calmodulin- and actin-binding protein of smooth muscle and nonmuscle cells
56. Cloning of drebrin A and induction of neurite-like processes in drebrin-transfected cells
57. Drebrin, a development-associated brain protein from rat embryo, causes the dissociation of tropomyosin from actin filaments
58. Drebrin is a widespread actin-associating protein enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells
59. F-actin bundles are derivatives of microvilli: What does this tell us about how bundles might form?
60. Comparative aspects of animal oogenesis
61. The villin-like protein encoded by the Drosophila quail gene is required for actin bundle assembly during oogenesis
62. Drosophila fascin mutants are rescued by overexpression of the villin-like protein, quail
63. F-actin bundles in Drosophila bristles are assembled from modules composed of short filaments
64. Forked proteins are components of fiber bundles present in developing bristles of Drosophila melanogaster
65. Changes in the F-actin cytoskeleton during neurosensory bristle development in Drosophila: The role of singed and forked proteins
66. Why are two different cross-linkers necessary for actin bundle formation in vivo and what does each cross-link contribute?
67. Regulation of actin filament cross-linking and bundle shape in Drosophila bristles
68. Perturbations of Drosophila alpha-actinin cause muscle paralysis, weakness, and atrophy but do not confer obvious nonmuscle phenotypes
69. Formation of the Drosophila ovarian ring canal inner rim depends on cheerio
70. Filamin is required for ring canal assembly and actin organization during Drosophila oogenesis
71. Drosophila filamin encoded by the cheerio locus is a component of ovarian ring canals
72. Dendritic cells: Unique leukocyte populations which control the primary immune response
73. Circulating human dendritic cells differentially express high levels of a 55-kd actin-bundling protein
74. The actin-bundling protein fascin is involved in the formation of dendritic processes in maturing epidermal Langerhans cells
75. Expression of the actin-bundling protein fascin in cultured human dendritic cells correlates with dendritic morphology and cell differentiation
76. Global expression analysis of extracellular matrix-integrin interactions in monocytes
77. Dendritic cells as vectors for therapy
78. The role of follicular and interdigitating dendritic cells in HIV-retated lymphoid hyperplasia: Localization of fascin
79. Alterations in fascin-expressing germinal center dendritic cells in neoplastic follicles of B-cell lymphomas
80. Fascin is involved in the antigen presentation activity of mature dendritic cells
81. Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breast cancer
82. Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor
83. Fascin, a sensitive new marker for Reed-Sternberg cells of hodgkin's disease. Evidence for a dendritic or B cell derivation?
84. Interdigitating dendritic cell sarcoma. A report of four cases and review of the literature
85. Mutation of human retinal fascin gene (fscn2) causes autosomal dominant retinitis pigmentosa
86. Hodgkin's disease expressing follicular dendritic cell marker CD21 without any other B-cell marker: A clinicopathologic study of nine cases
87. Alteration of peripheral blood dendritic cells in patients with primary Sjogren's syndrome
88. Detection of Kaposi's sarcoma herpesvirus DNA sequences in multiple myeloma bone marrow stromal cells
89. "Juvenile" xanthogranuloma: An immunophenotypic study with a reappraisal of histogenesis
90. Fascin and the differential diagnosis of childhood histiocytic lesions
91. Increased expression of fascin, motility associated protein, in cell cultures derived from ovarian cancer and in borderline and carcinomatous ovarian tumors