Novel regulation and dynamics of myosin II activation during epidermal wound responses

Experimental Cell Research

Volumn 316, Issue 6, 2010, Pages 980-991

  Betapudi, Venkaiah ^a   Rai, Vandana ^a   Beach, Jordan R ^a,b   Egelhoff, Thomas ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell migration; Cytoskeleton; Epidermis; Myosin II; Wound healing

Indexed keywords

CALCIUM; F ACTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN II; MYOSIN IIA; MYOSIN LIGHT CHAIN;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; GENE ACTIVATION; GENETIC REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; POLARIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SKIN INJURY; WOUND HEALING;

EID: 77649191869     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.01.024     Document Type: Article

References (22)

1. Sharma G.D., He J., and Bazan H.E. p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades. J. Biol. Chem. 278 (2003) 21989-21997
2. Baum C.L., and Arpey C.J. Normal cutaneous wound healing: clinical correlation with cellular and molecular events. Dermatol. Surg. 31 (2005) 674-686
3. Singer A.J., and Clark R.A. Cutaneous wound healing. N. Engl. J. Med. 341 (1999) 738-746
4. Ridley A.J., Schwartz M.A., Burridge K., Firtel R.A., Ginsberg M.H., Borisy G., Parsons J.T., and Horwitz A.R. Cell migration: integrating signals from front to back. Science 302 (2003) 1704-1709
5. Webb D.J., Donais K., Whitmore L.A., Thomas S.M., Turner C.E., Parsons J.T., and Horwitz A.F. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat. Cell Biol. 6 (2004) 154-161
6. Conti M.A., and Adelstein R.S. Nonmuscle myosin II moves in new directions. J. Cell Sci. 121 (2008) 11-18
7. Choi C.K., Vicente-Manzanares M., Zareno J., Whitmore L.A., Mogilner A., and Horwitz A.R. Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. Nat. Cell Biol. 10 (2008) 1039-1050
8. Vicente-Manzanares M., Koach M.A., Whitmore L., Lamers M.L., and Horwitz A.F. Segregation and activation of myosin IIB creates a rear in migrating cells. J. Cell Biol. 183 (2008) 543-554
9. Doyle A.D., Wang F.W., Matsumoto K., and Yamada K.M. One-dimensional topography underlies three-dimensional fibrillar cell migration. J. Cell Biol. 184 (2009) 481-490
10. Fuchs E., and Horsley V. More than one way to skin. Genes Dev. 22 (2008) 976-985
11. Welter J.F., Crish J.F., Agarwal C., and Eckert R.L. Fos-related antigen (Fra-1), junB, and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity. J. Biol. Chem. 270 (1995) 12614-12622
12. Betapudi V., Licate L.S., and Egelhoff T.T. Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration. Cancer Res. 66 (2006) 4725-4733
13. Golomb E., Ma X., Jana S.S., Preston Y.A., Kawamoto S., Shoham N.G., Goldin E., Conti M.A., Sellers J.R., and Adelstein R.S. Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol. Chem. 279 (2004) 2800-2808
14. Xu K.P., Ding Y., Ling J., Dong Z., and Yu F.S. Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 45 (2004) 813-820
15. Monslow J., Sato N., Mack J.A., and Maytin E.V. Wounding-induced synthesis of hyaluronic acid in organotypic epidermal cultures requires the release of heparin-binding EGF and activation of the EGFR. J. Invest. Dermatol. 129 (2009) 2046-2058
16. Pastore S., Mascia F., Mariani V., and Girolomoni G. The epidermal growth factor receptor system in skin repair and inflammation. J. Invest. Dermatol. 128 (2008) 1365-1374
17. Dulyaninova N.G., House R.P., Betapudi V., and Bresnick A.R. Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells. Mol. Biol. Cell 18 (2007) 3144-3155
18. Klemke R.L., Cai S., Giannini A.L., Gallagher P.J., de Lanerolle P., and Cheresh D.A. Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol. 137 (1997) 481-492
19. Bement W.M., Mandato C.A., and Kirsch M.N. Wound-induced assembly and closure of an actomyosin purse string in Xenopus oocytes. Curr. Biol. 9 (1999) 579-587
20. Shen S.S., and Steinhardt R.A. The mechanisms of cell membrane resealing in rabbit corneal epithelial cells. Curr. Eye Res. 30 (2005) 543-554
21. Clark A.G., Miller A.L., Vaughan E., Yu H.Y., Penkert R., and Bement W.M. Integration of single and multicellular wound Responses. Curr. Biol. 19 (2009) 1389-1395
22. Goldberg P.L., MacNaughton D.E., Clements R.T., Minnear F.L., and Vincent P.A. p38 MAPK activation by TGF-beta1 increases MLC phosphorylation and endothelial monolayer permeability. Am. J. Physiol. Lung Cell Mol. Physiol. 282 (2002) L146-L154