Neuroprotective effects of tempol on retinal ganglion cells in a partial optic nerve crush rat model with and without iron load

Experimental Eye Research

Volumn 90, Issue 2, 2010, Pages 254-260

  Thaler, Sebastian ^a   Fiedorowicz, Michal ^a,b   Rejdak, Robert ^a,b,c   Choragiewicz, Tomasz J ^a,c   Sulejczak, Dorota ^b   Stopa, Piotr ^a,c   Zarnowski, Tomasz ^c   Zrenner, Eberhart ^a   Grieb, Pawel ^b   Schuettauf, Frank ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Neuroprotection; Optic nerve crush; Oxidative stress; Peroxynitrite; Retinal ganglion cells; Superoxide dismutase; Tempol

Indexed keywords

3 NITROTYROSINE; IRON DEXTRAN; TEMPOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BODY WEIGHT; CALIBRATION; CELL COUNT; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; IRON OVERLOAD; NERVE CELL LESION; NERVE CRUSH; NEUROPROTECTION; NONHUMAN; OPTIC NERVE INJURY; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; SURVIVAL RATE;

ANIMALS; ANTIOXIDANTS; CELL COUNT; CELL SURVIVAL; CYCLIC N-OXIDES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMATINICS; IMMUNOENZYME TECHNIQUES; IRON OVERLOAD; IRON-DEXTRAN COMPLEX; NEUROPROTECTIVE AGENTS; OPTIC NERVE INJURIES; OXIDATIVE STRESS; RATS; RATS, INBRED BN; RETINAL DEGENERATION; RETINAL GANGLION CELLS; SPIN LABELS; TYROSINE;

EID: 77649190350     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2009.10.013     Document Type: Article

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