Identification of RNA linkage isomers by anion exchange purification with electrospray ionization mass spectrometry of automatically desalted phosphodiesterase-II digests

Analytical Biochemistry

Volumn 399, Issue 1, 2010, Pages 110-117

  Thayer, J R ^a   Puri, Nitin ^b   Burnett, Chris ^b   Hail, Mark ^c   Rao, Srinivasa ^a  

^a DIONEX CORPORATION   (United States)

^b Life Technologies Corporation   (United States)

^c Novatia   (United States)

Author keywords

2 5 Linkage identification; Aberrant linkage identification; Anion exchange HPLC; ESI MS; Linkage isomers; Oligonucleotide desalting; Polymer monolith; RNA purification

Indexed keywords

DESALINATION; DRUG PRODUCTS; ELECTRODEPOSITION; ELECTROSPRAY IONIZATION; ESTERS; IONS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OLIGONUCLEOTIDES; PLANTS (BOTANY); PURIFICATION; RNA;

ANION EXCHANGE; ESI-MS; LINKAGE IDENTIFICATION; LINKAGE ISOMERS; POLYMER MONOLITHS;

ISOMERS;

OLIGONUCLEOTIDE; POLYMER; RNA; SODIUM CHLORIDE; SPLEEN EXONUCLEASE;

ANALYTIC METHOD; ANION EXCHANGE; ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; ISOMER; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RNA PURIFICATION;

EID: 77649188794     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.11.009     Document Type: Article

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